piperidine image Phencyclidine structure.svg width 120 image2 Phencyclidine from xtal 3D balls.png width2 200 Clinical data Drugs.com drugs.com parent phencyclidine legal CA Schedule I legal ... 9,12 15H2 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey JTJMJGYZQZDUJJ UHFFFAOYSA N Phencyclidine ... The Efficacy of Sodium Channel Blockers to Prevent Phencyclidine Induced Cognitive Dysfunction in the Rat ... Acute administration of phencyclidine induces tonic activation of medial prefrontal cortex neurons ... and phencyclidine as NMDA receptor antagonists journal Bioorganic and medicinal chemistry letters volume ... DA, Price WA title Comparison of chlorpromazine, haloperidol and pimozide in the treatment of phencyclidine ... AJ, Adams PM title Effects of naloxone, metenkephalin, and morphine on phencyclidine induced ... in phencyclidine psychosis. Neuroscience Abstracts. 9 33, 1983, ref Pharmacokinetics PCP is metabolized ... from phencyclidine. Journal of Medicinal Chemistry . 1981 24 5 496 499 ref ref Chaudieu I, Vignon ... of phencyclidine binding and dopamine uptake by PCP analogs. Pharmacology Biochemistry and Behaviour ... that, like other NMDA receptor antagonist s, phencyclidine can cause a certain kind of brain damage ... changes induced in cerebrocortical neurons by phencyclidine and related drugs journal Science volume ... Phencyclidine has also been shown to cause schizophrenia like changes in N acetylaspartate and N ... title Chronic phencyclidine administration induces schizophrenia like changes in N acetylaspartate ... schizophrenia. ref cite journal doi 10.1080 00223980209604159 author Murray JB title Phencyclidine .... Citation needed date July 2011 Phencyclidine is known By whom date May 2011 to bind, with relatively ... book year 2005 author Zukin, Stephen R author2 Sloboda, Zili author3 Javitt, Daniel C chapter Phencyclidine PCP chapterurl http books.google.com books?id HtGb2wNsgn4C&pg PA324&dq Phencyclidine history&hl ... Phencyclidine 20history&f false editor Lowinson, Joyce H editor2 Ruiz, Pedro editor3 Millman, Robert ... more details
Unreferenced date December 2009 In chemistry, hydrochlorides are salt chemistry salt s resulting, or regarded as resulting, from the reaction of hydrochloric acid with an organic Base chemistry base mostly amine s . This is also known as muriate , derived from hydrochloric acid s other name muriatic acid. For example, reaction of pyridine C sub 5 sub H sub 5 sub N with hydrochloric acid HCl yields pyridine hydrochloride C sub 5 sub H sub 5 sub N HCl . Even though this style of formula is often used for denoting the hydrochlorides, the dot incorrectly implies that the two molecules are weakly bonded together rather, what is present is the salt C sub 5 sub H sub 5 sub NH sup sup Cl sup sup with the correct chemical name pyridinium pyridinium chloride . Hydrochloric salts are most often referred to by using the name of the base, then simply tagging on hydrochloride or HCl . For example, while crack cocaine is the Free base chemistry freebase of cocaine, the salt form is often referred to as cocaine HCl. Uses Converting insoluble amines into hydrochlorides is a common way to make them Solubility water and acid soluble . This is particularly desirable for substances used in medications. Many pharmaceutical substances are prepared as hydrochlorides so that they may be quickly released in the gastrointestinal tract the body usually absorbs a hydrochloride within fifteen or thirty minutes. Very often hydrochlorides of amines have longer shelf lives than their respective free bases. Hydrochlorides have wide medical applications, ranging from over the counter drug over the counter sinus relief to antidepressants and painkiller painkillers . See also Free base chemistry Quaternary ammonium cation Category Organochlorides Category Salts de Hydrochloride fr Chlorhydrate it Cloridrato nl Hydrochloride pl Chlorowodorki pt Cloridrato sv Hydroklorid ... more details
Polyallylamine hydrochloride CAS No. 71550 12 4 is a cationic polyelectrolyte prepared by the polymerization of allylamine . It can be used in combination with an anionic polyelectrolyte like poly sodium styrene sulfonate to form a layer by layer adsorbed film of negatively and positively charged polymers. ref cite journal last Antipov first A coauthors Dmitry Shchukin, Yuri Fedutik, Alexander I. Petrov, Gleb B. Sukhorukov, Helmuth Moehwald title Carbonate microparticles for hollow polyelectrolyte capsules fabrication journal Colloids and Surfaces A Physicochem. Eng. Aspects year 2003 volume 224 pages 175 183 doi 0.1016 S0927 7757 03 00195 X ref Poly allylamine hydrochloride has many biomedical applications. The most prominent use of this polyelectrolyte is in the field of cell encapsulation. A layer by layer method is used by alternating positively and negatively charged polyelectrolytes to build a barrier between the cell and the harsher outside environment. Upon cell lysis, the capsule of layered polyelectrolytes maintains its structural integrity and can be used for purposes such as drug delivery. ref cite journal last Antipov first A coauthors Gleb B. Sukhorukov, Edwin Donath, and Helmuth Moehwald title Sustained Release Properties of Polyelectrolyte Multilayer Capsules journal J. Phys. Chem. B year 2001 volume 105 pages 2281 2284 doi 10.1021 jp002184 ref References references Category Organic polymers Category Plastics Category Polyelectrolytes de Polyallylamin fr Poly hydrochlorure d allylamine ... more details
OrganicBox complete synthetic yes wiki name Phencyclidine name 1 1 phenylcyclohexyl piperidine ref 1 a GENERAL INFORMATION C 17 H 25 N 1 mass 243.387 ref 1 b abbreviation PCP image Image Phencyclidine structure.svg 150px Chemical structure of phencyclidine synonyms table style width 100 tr td style width 50 Angel dust hair mist br Animal tranquilizer br Aurora borealis br Busy bee br Cadillac br Crystal joints br Cycl ine ones br Dust br Elephant tranquilizer br Elysion br Embalming fluid br Goo d n br Gorilla biscuits br Green tea leaves br Hog Dust br Horse tracks tranquilizer br Kay Jay br Killer weed br Magic mist br Mint dew weed td td style vertical align top Mist br Monkey dust tranquilizer br Peace pill weed br Pits br Rocket fuel br Scuffle br Selma br Sernyl an br Sheets br Sherman br Snorts br Stardust br Super Kool br Super grass joint weed br Surfer br Trank s br Whack y weed br Wobble weed br Zombie dust td tr table DATABASES SMILES C1CCC CC1 C2 CC CC C2 N3CCCCC3 ref 1 c InChI 1 C17H25N c1 4 10 16 11 5 1 17 12 6 2 7 13 17 18 14 8 3 9 15 18 h1,4 5,10 11H,2 3,6 9,12 15H2 ref 1 d ATC prefix ATC suffix ATC supplemental CAS 60124 79 0 DrugBank EINECS PubChem 6468 ref 1 e PHYSICAL PROPERTIES Structure index of refraction abbe number dielectric constant magnetic susceptibility dipole moment U V data lambda max extinction coefficient Infrared data absorption bands NMR data proton NMR carbon NMR other NMR Spectrometry data mass spectrometry Phase behaviour delta f H o delta fus H o delta fus S o triple point K triple point C triple point Pa criticle point K criticle point C criticle point Pa Solid properties S o solid heat capacity solid density solid melting point C 46.5 melting point F melting point K Liquid properties delta vap H o delta vap S o S o liquid heat capacity liquid density liquid viscosity liquid boiling point C boiling point F boiling point K Gas properties S o gas heat capacity gas viscosity gas HAZARD PROPERTIES MSDS main hazards nfpa health nfpa ... more details
Chlorproguanil dapsone artesunate abbreviated CDA is a new antimalarial treatment that entered Phase III clinical trials in 2006. It consists of chlorproguanil hydrochloride , dapsone , and artesunate . It can also be interpreted as Lapdap artesunate . It is being compared against artemether lumefantrine Coartem and against chlorproguanil dapsone Lapdap . This drug is being developed in collaboration between GlaxoSmithKline , UNICEF , the World Bank Group World Bank , Medicines for Malaria Venture and the World Health Organisation WHO Special Programme for Research and Training in Tropical Diseases WHO TDR , the Liverpool School of Tropical Medicine , and the London School of Hygiene and Tropical Medicine . ref cite journal journal Lancet Infect Dis year 2006 volume 6 issue 9 pages 551 author Das P title Promising anti malarial enters phase II studies. doi 10.1016 S1473 3099 06 70571 0 ref References reflist External links http www.who.int tdr index.html Special Programme for Research and Training in Tropical Diseases Category Antimalarial agents antimicrobial stub Antiprotozoal agent ... more details
title Receptor site topographies for phencyclidine like and sigma drugs predictions from quantitative ... R title Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake ... and molecular properties of phencyclidine like compounds by chemometrics journal Arzneimittel ... Arylcyclohexylamine Ketamine Phencyclidine References Reflist Depressants Hallucinogens Glutamatergics ... more details
R title Role of the aromatic group in the inhibition of phencyclidine binding and dopamine uptake ... and molecular properties of phencyclidine like compounds by chemometrics journal Arzneimittel ... isomer it has around the same potency as Phencyclidine PCP . 4 Meo PCP was reportedly first sold ... more details
Drugbox verifiedrevid 267631655 IUPAC name 1 cyclohexyl 1 phenyl 3 pyrrolidin 1 yl propan 1 ol hydrochloride image Procyclidine hydrochloride 2D skeletal.png Clinical data tradename Drugs.com drugs.com monograph procyclidine hydrochloride MedlinePlus a605037 pregnancy category legal status routes of administration oral, intramuscular im , intravenous iv Pharmacokinetic data bioavailability protein bound 100 albumin metabolism elimination half life 12 h excretion Identifiers CASNo Ref cascite CAS number 77 37 2 CAS supplemental br 77 37 2 free base CAS verified ATC prefix N04 ATC suffix AA04 PubChem 207841 DrugBank APRD00383 ChemSpiderID 4750 UNII Ref fdacite correct FDA UNII C6QE1Q1TKR ChEMBL Ref ebicite correct EBI ChEMBL 1761 Chemical data C 19 H 30 Cl 1 N 1 O 1 molecular weight 323.9 g mol confuse Phencyclidine Procyclidine is an anticholinergic medication drug principally used for the treatment of Drug induced parkinsonism , akathisia and acute dystonia Parkinson disease and Idiopathic or secondary dystonia . Uses It is used in patients with parkinsonism and akathisia and to reduce the side effects of antipsychotic treatment given for schizophrenia . Procyclidine is also a second line drug for the treatment of Parkinson s disease . It improves tremor but not rigidity or bradykinesia . Procyclidine is also sometimes used for the treatment of dystonia but not tardive dyskinesia , a rare disorder that causes abnormal muscle contraction, resulting in twisting postures of limbs, trunk, or face. Overdose Signs of procyclidine overdose are those of an anticholinergic and include confusion, agitation and sleeplessness that can last up to or more than 24 hours. Pupils become dilated and unreactive to light. Tachycardia fast heart beat , as well as auditory and visual hallucinations have also been reported. Other known symptoms of overdose are clumsiness or unsteadiness, being severely drowsy, having a severely dry mouth, nose, or throat, having an altered mood or other mental ... more details
Drugbox verifiedrevid 443622743 IUPAC name 2 ethylamino 2 2 thienyl cyclohexanone image Tiletamine.svg Clinical data tradename Drugs.com drugs.com international tiletamine pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US Schedule III legal status routes of administration Intravenous therapy IV , Intramuscular injection IM , Subcutaneous injection SC , Other Pharmacokinetic data bioavailability protein bound metabolism Liver elimination half life excretion Kidneys Identifiers CAS number ATC prefix none ATC suffix PubChem 26533 DrugBank Ref drugbankcite correct drugbank DrugBank ChemSpiderID Ref chemspidercite correct chemspider ChemSpiderID 24714 UNII Ref fdacite correct FDA UNII 2YFC543249 KEGG Ref keggcite correct kegg KEGG D08596 Chemical data C 12 H 17 N 1 O 1 S 1 molecular weight 223.34 g mol smiles O C2C c1sccc1 NCC CCCC2 InChI 1 C12H17NOS c1 2 13 12 11 7 5 9 15 11 8 4 3 6 10 12 14 h5,7,9,13H,2 4,6,8H2,1H3 InChIKey QAXBVGVYDCAVLV UHFFFAOYAJ StdInChI Ref stdinchicite correct chemspider StdInChI 1S C12H17NOS c1 2 13 12 11 7 5 9 15 11 8 4 3 6 10 12 14 h5,7,9,13H,2 4,6,8H2,1H3 StdInChIKey Ref stdinchicite correct chemspider StdInChIKey QAXBVGVYDCAVLV UHFFFAOYSA N Tiletamine is a dissociative anesthetic and pharmacology pharmacologically classified as an NMDA receptor antagonist . It is related chemically and pharmacologically to other anesthetics in this family such as ketamine and phencyclidine . Tiletamine hydrochloride exists as odourless white crystals. It is used in veterinary medicine in the compound product Telazol tiletamine zolazepam , 50 mg ml of each in 5 ml vial as an injectable anesthetic. It is sometimes used in combination with xylazine Rompun to tranquilize large mammal s such as bear s and horse s. Telazol is the only commercially available tiletamine product in the Unit ... more details
Summary Molecular structure of sevelamer hydrochloride. Created with ChemDraw. Licensing GFDL self with disclaimers migration relicense Copy to Wikimedia Commons bot Fbot Orphan image ... more details
Nuzak may refer to Anders Wollbeck , a Swedish musician Fluoxetine hydrochloride , an antidepressant Long comment to avoid being listed on short pages disambig ... more details
9055 Desomorphine 9145 Dihydromorphine 9335 Drotebanol 9056 Etorphine except hydrochloride salt ... s THC 7455 Eticyclidine Ethylamine analog of phencyclidine Eticyclidine PCE 7458 Rolicyclidine Pyrrolidine analog of phencyclidine PCPy 7470 Tenocyclidine Thiophene analog of phencyclidine TCP Depressants ... more details
Monocaine or monocane may refer to Monocaine hydrochloride butethamine hydrochloride , a local anesthetic Monocane, a fictional chemical in the 1933 horror film The Invisible Man film The Invisible Man Monocane, a fictional poison in the List of Matlock episodes Matlock episodes The Nurse and The Hucksters Monocane, a fictional poison in the Perry Mason TV movie A Perry Mason Mystery The Case of the Lethal Lifestyle Monocane, a fictional poison in the McBride TV series McBride TV movie The Doctor is Out ... Really Out Disambig ... more details
Minitran Ltd is a leading UK distributor of Structured Cabling Systems www.minitran.co.uk Minitran is a commercial psychiatric medication psychiatric drug tranquilliser and antidepressant manufactured in Greece by Adelco S.A. and sold in form of yellow coloured sugar coated tablets. It contains Amitriptyline hydrochloride and Perphenazine . It is sold in the following forms Minitran 2 10 2 mg Perphenazine and 10 mg Amitriptyline hydrochloride in each tablet. Minitran 2 25 2 mg Perphenazine and 25 mg Amitriptyline hydrochloride in each tablet. Minitran 4 10 4 mg Perphenazine and 10 mg Amitriptyline hydrochloride in each tablet. Minitran 4 25 4 mg Perphenazine and 25 mg Amitriptyline hydrochloride in each tablet. Minitran is also a pharmaceutical drug for the treatment of Angina pectoris Angina , manufacturered by 3M . It contains glyceryl trinitrate and is sold in patch form. It is sold in the following strengths Minitran 5 contains 18 mg of glyceryl trinitrate and delivers 5 mg in 24 hours Minitran 10 contains 36 mg of glyceryl trinitrate and delivers 10 mg in 24 hours Minitran 15 contains 54 mg of glyceryl trinitrate and delivers 15 mg in 24 hours It is also marketed as Discotrine in some countries. See also List of psychiatric drugs Psychiatry Category Antidepressants Category Sedatives ... more details
Papaveretum British Approved Name BAN is a preparation containing a mixture of hydrochloride salts of opium alkaloid s. Since 1993, papaveretum has been defined in the British Pharmacopoeia BP as a mixture of 253 parts morphine morphine hydrochloride , 23 parts papaverine papaverine hydrochloride , and 20 parts codeine codeine hydrochloride Sweetman, 2004 . It is commonly marketed to medical agencies under the trade name Omnopon . Although the use of papaveretum is now relatively uncommon following the wide availability of single component opiate s and synthetic opioid s e.g. pethidine it is still used to relieve moderate to severe pain and for pre operative sedation. In clinical settings, papaveretum is usually administered to patients via subcutaneous , intramuscular or intravenous routes. Additionally, the morphine syrette s found in combat medical kits issued to military personnel actually contain omnopon. Prior to 1993, papaveretum also contained noscapine , though this component was removed from the BP formulation due to the genotoxic potential of noscapine. See also Morphine Papaverine Codeine External links ATC N02 AA10 References cite book editor Edited by Sean C. Sweetman title Martindale The complete drug reference edition 34th edition date November 30, 2004 publisher Pharmaceutical Press location London isbn 0 85369 550 4 Opioids Category Opiates ru ... more details
Summary Information Description a microscopic view of a grain of cocaine hydrochloride in a dollar bill Source http thesho.com Drugs stimulant pictures.htm Date Author Permission this was a free image circulating the news groups other versions Licensing PD USGov Copy to Wikimedia Commons bot Svenbot priority true ... more details
An ataractive is a type of drug which diminishes hallucination s in patients exhibiting them. ref name pmid13368052 cite journal author BRAUN DL, BROWN BB, FELDMAN RG title The pharmacologic activity of alpha 4 piperidyl benzhydrol hydrochloride azacyclonol hydrochloride an ataractive agent journal The Journal of Pharmacology and Experimental Therapeutics volume 118 issue 2 pages 153 61 year 1956 month October pmid 13368052 doi url http jpet.aspetjournals.org cgi pmidlookup?view long&pmid 13368052 ref Examples include azacyclonol ref name pmid13368052 cite journal author BRAUN DL, BROWN BB, FELDMAN RG title The pharmacologic activity of alpha 4 piperidyl benzhydrol hydrochloride azacyclonol hydrochloride an ataractive agent journal The Journal of Pharmacology and Experimental Therapeutics volume 118 issue 2 pages 153 61 year 1956 month October pmid 13368052 doi url http jpet.aspetjournals.org cgi pmidlookup?view long&pmid 13368052 ref and atypical antipsychotic s. See also Antipsychotic Tranquilizer References Reflist Category Antipsychotics nervous system drug stub ... more details
Zombie dust can refer to Zombie dust narcotic , a mixture of Triazolam and Cocaine Phencyclidine , commonly known as PCP Zombie Dust, an American Pale Ale by Three Floyds Brewing Company disambig Short pages monitor This long comment was added to the page to prevent it being listed on Special Shortpages. It and the accompanying monitoring template were generated via Template Longcomment. Please do not remove the monitor template without removing the comment as well. ... more details
Oleptro is a pharmaceutical brand name of Trazodone hydrochloride , a triazolopyridine antidepressant drug, manufactured and marketed by Labopharm Europe Limited, Dublin, Ireland. It was approved by the FDA in February 2010 for use in the form of extended release tablets Initial U.S. Approval 1981 ref cite web url http www.theodora.com drugs oleptro trazodone hydrochloride extended release tablets labopharm europe ltd.html title Oleptro Full Prescribing Information in Drug Reference Encyclopedia format work accessdate 2010 02 16 . ref References reflist 1 External links http www.labopharm.com Labopharm Europe Ltd. corporate website Category Antidepressants ... more details
name AHFS cite web title Amitriptyline Hydrochloride url http www.drugs.com monograph amitriptyline ... binding site as phencyclidine . ref name pmid2568580 Cite pmid 2568580 ref Amitriptyline inhibits ... profs Datasheet a Amitriptab.htm AMITRIP Amitriptyline hydrochloride 10 mg, 25 mg and 50 mg ... more details
Macmillan isbn 0312252434 ref Parke Davis also was the original manufacturer and patent holder of phencyclidine ... Ketalar ketamine hydrochloride , a general anesthetic and dissociative drug, in 1962. Due to the severe ... more details
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