Neuron map Myelin sheath Myelin is a dielectric Insulator electrical electrically insulating material that forms a layer, the myelin sheath , usually around only the axon of a neuron . It is essential for the proper functioning of the nervous system . Myelin is an outgrowth of a type of glial cell . The production of the myelin sheath is called myelination. In humans, the production of myelin begins in the fourteenth week of fetal development, although little myelin exists in the brain at the time .... Schwann cell s supply the myelin for peripheral neurons, whereas oligodendrocyte s, specifically of the interfascicular type, myelinate the axons of the central nervous system . Myelin is considered a defining characteristic of the gnathostome gnathostome vertebrates , but myelin like sheaths ... vertebrate myelin at the molecular level. ref cite journal author Hartline DK, Colman DR title Rapid ... issue 1 pages R29 35 year 2007 month January pmid 17208176 doi 10.1016 j.cub.2006.11.042 ref Myelin .... Pathol. Anat. volume 6 pages 562 72 year 1854 ref Composition of myelinMyelin may be made by different ... function. Myelinated axons are white in appearance, hence the white matter of the brain. Myelin is about 40 water the dry mass of myelin is about 70 85 lipids and about 15 30 proteins . http www.ncbi.nlm.nih.gov books NBK28221 Some of the proteins that make up myelin are myelin basic protein MBP , myelin oligodendrocyte glycoprotein MOG , and proteolipid protein PLP . The primary lipid of myelin ... serve to strengthen the myelin sheath. Function of myelin layer Image Myelinated neuron.jpg thumb ... at Trinity College, Hartford, CT. The main purpose of a myelin layer or sheath is to increase the speed ... conduction saltation . Myelin increases electrical resistance across the cell membrane by a factor ..., the myelin sheath provides a track along which regrowth can occur. Unfortunately, the myelin layer ... without re growth. Damage to the myelin sheath and nerve fiber is often associated with increased ... more details
Myelin Media is a privately held video game publisher owned by the hedge fund Icahn Associates Corporation located in New York, NY. Myelin specializes in working with Video game developer Independent developers independent video game developers to promote creative titles. It provides unusual marketing venues such as linking titles with National Geographic and MTV . Games published Children of the Nile City building game City building game Stacked with Daniel Negreanu Poker game External links http www.myelinmedia.com Myelin Media web site Category Video game companies of the United States Category Companies based in New York City es Myelin Media sv Myelin Media ... more details
Context date October 2009 Infobox Anatomy Name Myelin incisure Latin GraySubject 183 GrayPage 727 Image Gray631.png Caption Diagram of longitudinal sections of medullated nerve fiber s. Incisure labeled at upper left. Image2 Caption2 System MeshName MeshNumber DorlandsPre i 05 DorlandsSuf 12447772 Code TerminologiaHistologica 2 00 06.2.03015 In the peripheral nervous system PNS axons can be either myelinated or unmyelinated. Myelination means that the axon is insulated by surrounding layers of fatty membrane myelin produced by Schwann cells . These layers are continuous like rolling up rope , but, due to the way they are formed, they often include small amounts of Schwann cell cytoplasm not displaced to the periphery during Schwann cell formation of the myelin. These are the so called Myelin incisures or Schmidt Lanterman clefts a.k.a. Schmidt Lanterman incisures,clefts of Schmidt Lanterman, segments of Lanterman, medullary segments , which subdivide the myelinated axon into irregular portions. They are histology histological evidence of the small amount of cytoplasm that remains in the inner layer of the myelin sheath created by Schwann cell s wrapping tightly around a nerve . External links eMedicineDictionary Schmidt Lanterman incisures BUHistology 22801loa Gray s Nervous tissue Category Nervous system neuroscience stub fr Incisures de Schmidt Lanterman it Incisure di Schmidt Lanterman es Cisuras de Schmidt Lanterman ... more details
The Myelin Project is an international scientific research organization aimed at accelerating clinical and translational research focused on myelin repair and to regenerate the nerve nerve s myelinmyelin sheath , &ndash a process called remyelination &ndash destroyed in a host of diseases such as multiple sclerosis and the leukodystrophy leukodystrophies . The Myelin Project was established in 1989 with the aim of funding accelerated research on the demyelinating diseases, such as the leukodystrophies and multiple sclerosis. The organization was founded by Augusto Odone and his late wife, Michaela. Their son, Lorenzo, suffered from X linked adrenoleukodystrophy X ALD , the most common of the leukodystrophies. The story of the Odones struggle was dramatized in the film Lorenzo s Oil , starring Nick Nolte and Susan Sarandon , released by Universal Studios in 1992. The project s aims The Myelin Project aims to accelerate research on myelin repair. Myelin can be destroyed by hereditary neurodegenerative disorders such as the leukodystrophies, and by other diseases such as multiple sclerosis. All together, demyelinating diseases affect more than two million people worldwide. The Myelin Project headquarters has recently moved from Amarillo, Texas where it was housed on the Texas Tech University Health Sciences Center campus in the Laura W. Bush Institute for Women s Research to Pacific ... for the Myelin Project, with son Greg as her Executive Assistant. Patti had two brothers ... are also volunteers. Using a motivated, time conscious approach to attain specific goals, The Myelin Project has set up a Work Group from among the top international laboratories specializing in myelin .... The Myelin Project targets its funds toward clinically oriented experiments on the cutting edge ... sign language. It is also related that the Odones have founded The Myelin Project which focuses on researching ... The Myelin Project s home page DEFAULTSORT Myelin Project Category Research organizations it Progetto ... more details
enzyme Name myelin proteolipid O palmitoyltransferase EC number 2.3.1.100 CAS number 82657 98 5 IUBMB EC number 2 3 1 100 GO code 0047157 image width caption In enzymology , a myelin proteolipid O palmitoyltransferase EC number 2.3.1.100 is an enzyme that catalysis catalyzes the chemical reaction palmitoyl CoA myelin proteolipid math rightleftharpoons math CoA O palmitoyl myelin proteolipid Thus, the two substrate biochemistry substrates of this enzyme are palmitoyl CoA and myelin proteolipid , whereas its two product chemistry products are coenzyme A CoA and O palmitoyl myelin proteolipid . This enzyme belongs to the family of transferase s, specifically those acyltransferase s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is palmitoyl CoA myelin proteolipid O palmitoyltransferase . Other names in common use include myelin PLP acyltransferase , acyl protein synthetase , and myelin proteolipid O palmitoyltransferase . References reflist 1 cite journal author Bizzozero OA, McGarry JF, Lees MB date 1987 title Acylation of endogenous myelin proteolipid protein with different acyl CoAs journal J. Biol. Chem. volume 262 pages 2138&ndash 45 pmid 3818589 issue 5 DEFAULTSORT Myelin proteolipid O palmitoyltransferase Category EC 2.3.1 Category Enzymes of unknown structure transferase stub ... more details
protein Name myelin associated glycoprotein caption image width HGNCid 6783 Symbol MAG AltSymbols GMA EntrezGene 4099 OMIM 159460 RefSeq NM 080600 UniProt P20916 PDB ECnumber Chromosome 19 Arm q Band 13.1 LocusSupplementaryData Myelin associated glycoprotein MAG, Siglec 4 is a cell membrane glycoprotein that is a member of the SIGLEC family of proteins and is a functional ligand of the NOGO 66 receptor, NgR . ref cite journal author Quarles RH title Myelin associated glycoprotein MAG past, present and beyond journal Journal of Neurochemistry volume 100 issue 6 pages 1431 48 year 2007 pmid 17241126 doi 10.1111 j.1471 4159.2006.04319.x ref MAG is believed to be involved in myelination during nerve regeneration. ref cite journal author Barton D, Arquint M, Roder J, Dunn R, Francke U title The myelin associated glycoprotein gene mapping to human chromosome 19 and mouse chromosome 7 and expression in quivering mice journal Genomics volume 1 issue 2 pages 107 12 year 1987 pmid 2447011 doi 10.1016 0888 7543 87 90002 4 ref See also Myelin External links MeshName Myelin associated glycoprotein References references Category Lectins Category SIGLEC lectins Cell membrane proteins gene 19 stub nl Myeline gebonden glycoprote ne ... more details
Pfam box Symbol Myelin PLP Name Myelin proteolipid protein PLP or lipophilin image width caption Pfam PF01275 InterPro IPR001614 SMART SM00002 Prosite PDOC00497 SCOP TCDB OPM family OPM protein PDB Myelin proteolipid protein PLP or lipophilin ref name PUB00003190 cite journal doi 10.1007 BF01868534 author Dautigny A, Popot JL, Pham Dinh D title Major Myelin proteolipid the 4 alpha helix topology journal J. Membr. Biol. volume 120 issue 3 pages 233 246 year 1991 pmid 1711121 ref is the major myelin protein from the central nervous system CNS . It plays an important role in the formation or maintenance of the multilamellar structure of myelin . The myelin sheath is a multi layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. ref name PUB00002447 cite journal author Kitamura K, Sakamoto Y, Yoshimura K, Nishijima T, Uyemura K title Complete amino acid sequence of PO protein in bovine peripheral nerve myelin journal J. Biol. Chem. volume 262 issue 9 pages 4208 4214 year 1987 pmid 2435734 ref In man point mutations in PLP are the cause of Pelizaeus Merzbacher disease PMD , a neurologic disorder of myelin metabolism. In animals dismyelinating diseases such as mouse jimpy or dog shaking pup are also caused by mutations in PLP. PLP is a highly conserved ref name PUB00000749 cite journal author Stoffel W, Schliess F title Evolution of the myelin integral membrane proteins of the central nervous system journal Biol. Chem. Hoppe Seyler volume 372 issue 9 pages 865 874 year 1991 pmid 1722981 doi 10.1515 bchm3.1991.372.2.865 ref hydrophobic protein of 276 to 280 amino acids which seems to contain four transmembrane segments, two disulfide bond s and which covalently binds lipids at least six palmitate groups in mammals . ref name PUB00000360 cite journal doi 10.1021 bi00164a002 author Weimbs T, Sto ffel W title Proteolipid protein PLP of CNS myelin positions of free, disulfide bonded, and fatty ... more details
PBB geneid 4359 Myelin protein zero P0 is a glycoprotein associated with Charcot Marie Tooth disease .... See Template PBB Controls to Stop updates. PBB Summary section title summary text Myelin protein zero is the major structural protein of peripheral myelin. supplied by OMIM ref cite web title Entrez Gene MPZ myelin protein zero Charcot Marie Tooth neuropathy 1B url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 4359 accessdate ref Interactions Myelin protein zero has been shown to Protein protein interaction interact with Peripheral myelin protein 22 . ref name ... month May. title Peripheral myelin protein 22 and protein zero a novel association in peripheral nervous system myelin journal J. Neurosci. volume 19 issue 9 pages 3396 403 publisher location UNITED ... laydate quote ref See also myelin References reflist Further reading refbegin 2 PBB Further reading ... in the peripheral myelin genes and associated genes in inherited peripheral neuropathies. journal ... responsive asymmetric neuropathy with a myelin protein zero gene mutation. journal Neurology ... of myelin related proteins PMP22, MPZ and Cx32 a clinicopathological study of 205 Japanese ... awg012 cite journal author Shy ME title Peripheral neuropathies caused by mutations in the myelin ... and sequence determination of cDNA encoding the major structural protein of human peripheral myelin ... and chromosomal localization of the gene encoding the human myelin protein zero MPZ . journal ... author Su Y, Brooks DG, Li L, et al. title Myelin protein zero gene mutated in Charcot Marie tooth ... T, et al. title New mutation of the myelin P0 gene in a pedigree of Charcot Marie Tooth neuropathy ... journal author Hayasaka K, Himoro M, Sawaishi Y, et al. title De novo mutation of the myelin P0 gene ... Dinh D, Fourbil Y, Blanquet F, et al. title The major peripheral myelin protein zero gene structure ... Rapid screening of myelin genes in CMT1 patients by SSCP analysis identification of new mutations and polymorphisms ... more details
The Myelin Repair Foundation MRF is a 501 c 3 not for profit organization based in Saratoga, California . The organization applies a collaborative business model to the process of medical research with the aim of accelerating the identification and development of new patient treatments. MRF s goal is to license its first drug target for commercial drug development by July 1, 2009, five years after the organization began funding research. ref http myelinrepair.org about vision mission.shtml Myelin Repair Foundation, Vision and Mission. ref The MRF was created by entrepreneur Scott Johnson in 2002, and began funding research in 2004. Background The Myelin Repair Foundation was founded in 2002 by Scott Johnson, a California entrepreneur. Johnson had been diagnosed with multiple sclerosis at the age of 20. When given his prognosis, he was told that an effective therapy would probably not be on the market for another 30 to 50 years. If someone is diagnosed now they d probably hear the same thing, Johnson says. And that s pretty frustrating. ref http myelinrepair.org myelinvid index.shtml Myelin ... the Myelin Repair Foundation, a not for profit with a business inspired research model. The ARC Model ... process where new treatments are produced. ref Myelin Repair Foundation, Accelerated Research Collaboration ... Myelin Repair Foundation , Myelin Repair Foundation Launches First of a Kind Drug Discovery Advisory ... about board and advisors.shtml Myelin Repair Foundation, Board and Advisors. ref Funding The MRF .... ref Myelin Repair Foundation , FAQ Who supports the Myelin Repair Foundation? http myelinrepair.org ... Radicals , by Julia Moulden . ref http myelinrepair.org news Myelin Repair Foundation, MRF Newsroom ... External links http www.myelinrepair.org Myelin Repair Foundation Begley, Sharon. Wall Street ... 28 080128fa fact groopman?currentPage all Hagel, John, and John Seely Brown. Myelin Repair Foundation ... documents SFGate MRF reprint 2008 03 29.pdf Forbes . Opexa Therapeutics and the Myelin Repair Foundation ... more details
PBB geneid 5376 Peripheral myelin protein 22 , also known as PMP22 , is a protein which in humans is encoded by the PMP22 gene . Alternative splicing of this gene results in three transcript variants that encode the same protein. ref cite web title Entrez Gene PMP22 peripheral myelin protein 22 url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 5376 accessdate ref Function The integral membrane protein encoded by this gene is a hydrophobic, tetraspan glycoprotein expressed mainly in Schwann cell s and is a major component of compact myelin in the peripheral nervous system . ref name pmid1556154 cite journal author Snipes GJ, Suter U, Welcher AA, Shooter EM title Characterization of a novel peripheral nervous system myelin protein PMP 22 SR13 journal The Journal of Cell Biology volume 117 issue 1 pages 225 38 year 1992 month April pmid 1556154 pmc 2289391 doi 10.1083 jcb.117.1.225 url issn ref Clinical significance Various mutations of the gene are causes of Charcot Marie Tooth disease type IA, Dejerine Sottas disease , and hereditary neuropathy with liability to pressure palsies HNPP . Interactions Peripheral myelin protein 22 has been shown to Protein protein interaction interact with Myelin protein zero . ref name pmid10212299 cite journal last D Urso first D authorlink coauthors Ehrhardt P, M ller H W year 1999 month May. title Peripheral myelin protein 22 and protein zero a novel association in peripheral nervous system myelin journal J. Neurosci. volume 19 issue 9 pages 3396 403 publisher location UNITED STATES issn 0270 6474 pmid 10212299 bibcode oclc id url language format accessdate laysummary laysource laydate quote ref References reflist Further reading refbegin 2 PBB Further reading citations cite journal author Patel PI, Lupski ... Nelis E, Haites N, Van Broeckhoven C title Mutations in the peripheral myelin genes and associated ... AM, Suter U title The peripheral myelin protein 22 and epithelial membrane protein family. journal ... more details
PBB geneid 4155 Myelin basic protein MBP is a protein believed to be important in the process of myelin ... after isolation from myelin cell membrane membrane s. ref name pmid5096093 Since that time, knockout ... encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocyte ... the well characterized myelin basic proteins. This complex gene structure is conserved among species ... cite web title Entrez Gene myelin basic protein url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ... an increase in mortality rate between 0 and 40 . ref name pmid17507463 Interactions Myelin basic protein ... EH, Brostoff S, Hashim G, Caccam J, Burnett P title Basic A1 protein of the myelin membrane. The complete ... N, Hood L, Simon MI title Localization of the human myelin basic protein gene MBP to region 18q22 qter ... Wood DD, Vella GJ, Moscarello MA title Interaction between human myelin basic protein and lipophilin ... JB, Braun PE title Interaction of myelin basic protein and proteolipid protein journal J. Neurosci. Res ... TM, Popko B, et al. title Repetitive DNA TGGA n 5 to the human myelin basic protein gene a new ... A, Nishiyama K, Nakanishi H, et al. title Studies on the phosphorylation of myelin basic protein ... N, Hood L, Simon MI title Localization of the human myelin basic protein gene MBP to region 18q22 ... R title Identification of three forms of human myelin basic protein by cDNA cloning. journal Proc ... sequence of human myelin basic protein peptides 1 44 and 90 170 by fast atom bombardment mass spectrometry ... and characterization of a cDNA coding for a novel human 17.3K myelin basic protein MBP variant ... cite journal author Popko B, Puckett C, Lai E, et al. title Myelin deficient mice expression of myelin basic protein and generation of mice with varying levels of myelin. journal Cell volume 48 ... J, Spielman R, Gogolin K, et al. title The human myelin basic protein gene chromosomal localization ... for the expression of four myelin basic protein variants in the developing human spinal cord ... more details
PBB geneid 4340 Myelin Oligodendrocyte Glycoprotein MOG is a glycoprotein believed to be important in the process of myelin ization of nerve s in the central nervous system CNS . In humans this protein ..., Kerlero de Rosbo N, Dautigny A title Structure of the human myelin oligodendrocyte glycoprotein gene ... N, Pontarotti P, Coppin H title The human myelin oligodendrocyte glycoprotein MOG gene complete nucleotide ... adhesion molecule to provide structural integrity to the myelin sheath and is known to develop ... of MOG is not yet known, its likely role with the myelin sheath is either in sheath completion ... molecule on the myelin sheath of the CNS to provide the structural integrity of the myelin sheath ... JL, Dautigny A title Characterization and expression of the cDNA coding for the human myelin oligodendrocyte ..., Artzt K, Lindahl KF, Dautigny A title Myelin oligodendrocyte glycoprotein is a member of a subset ... surface of myelin sheath s. MOG is a quantitatively minor type I transmembrane protein ..., G et Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects ... structure of myelin oligodendrocyte glycoprotein was determined by x ray diffraction at a resolution ... A, Zander H, et al. title Structural insights into the antigenicity of myelin oligodendrocyte ... a role as an adhesin in the completion and or compaction of the myelin sheath. There is a significant ... journal author Clements CS, Reid HH, Beddoe T, et al. title The crystal structure of myelin oligodendrocyte ... pnas.1833158100 url ref Synthesis Developmentally, MOG is formed very late on oligodendrocytes and the myelin ... Anti myelin antibodies predict the clinical outcome after a first episode suggestive of MS journal ... among a large number of various antigens in some of the studies that will be mentioned. One is myelin ... MS. ref name Berger1 The other is myelin oligodendrocyte glycoproteins MOG . Both have been identified ... J, Lauterburg T, Walker U, R sler KM, Mattle HP title Anti myelin antibodies in clinically isolated ... more details
Lymph MeshName MeshNumber Code TerminologiaHistologica 2 00 06.2.03015 Myelin sheath gaps or nodes of Ranvier are the gaps approximately 1 micrometre micrometer in length formed between the myelin sheath s generated by different cells. A myelin sheath is a many layered coating, largely composed of a fatty substance called myelin, that wraps around the axon of a neuron and very efficiently insulates ... electrical activity. Overview Neuron map Node of Ranvier Many vertebrate axons are surrounded by a myelin ... glial membranes are fused to form compact myelin , whereas the cytoplasm filled paranodal loops ... Image Louis Antoine Ranvier.jpg thumb left Louis Antoine Ranvier 1835 1922 The myelin sheath of long ... later discovered the nodes, or gaps, in the myelin sheath that now bear his name. Born in Lyon ... examination of myelin sheaths and Schwann cells. ref cite journal author Barbara J.G. year ... myelin segments that are referred to as internodes. The size and the spacing of the internodes vary ... paranodal regions are distinct from the internodes under the compact myelin sheath, but are very ... myelin sheath, and inner collar of cytoplasm, and the axolemma. At the paranodal regions, the paranodal ... of the extension of the myelin sheath in its cross sectional diameter is easily ascertained ... in length of the myelin sheath can be accounted solely by the increase in length of axon covered ... along an axon, the directions of the directions of the lamellar overhang of the myelin endings ..., Caldwell JH, Mandel G, Trimmer JS et al. year 2001 title Compact myelin dictates the differential ... directly with the formation of compact myelin . In mature nodal regions, interactions with the intracellular ... that the accumulation of OMgp in the nodes might depend on myelin integrity and sub cellular ..., as they do in axons that lack a myelin sheath. The clustering of voltage gated sodium and potassium ... over conduction that occurs along an axon without myelin sheaths. First, it saves energy by decreasing ... more details
enzyme Name myelin basic protein arginine N methyltransferase EC number 2.1.1.126 CAS number 9055 07 6 IUBMB EC number 2 1 1 126 GO code 0016277 image width caption In enzymology , a myelin basic protein arginine N methyltransferase EC number 2.1.1.126 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine myelin basic protein arginine math rightleftharpoons math S adenosyl L homocysteine myelin basic protein Nomega methyl arginine Thus, the two substrate biochemistry substrates of this enzyme are S Adenosyl methionine S adenosyl methionine and myelin basic protein arginine , whereas its two product chemistry products are S adenosylhomocysteine and myelin basic protein Nomega methyl arginine . This enzyme belongs to the family of transferase s, specifically those transferring one carbon group methyltransferases. The systematic name of this enzyme class is S adenosyl L methionine myelin basic protein arginine Nomega methyltransferase . Other names in common use include myelin basic protein methylase I , protein methylase I , S adenosyl L methionine myelin basic protein arginine , and omega N methyltransferase . References reflist 1 cite journal author Ghosh SK, Paik WK, Kim S date 1988 title Purification and molecular identification of two protein methylases I from calf brain. Myelin basic protein and histone specific enzyme journal J. Biol. Chem. volume 263 pages 19024&ndash 33 pmid 2461933 issue 35 DEFAULTSORT Myelin Basic Protein Arginine N Methyltransferase Category EC 2.1.1 Category Enzymes of unknown structure it proteina basica della mielina arginina N metiltransferasi transferase stub ... more details
Unreferenced date January 2007 The Redlich Obersteiner s zone is a boundary between the central nervous system CNS , the peripheral nervous system PNS . The Redlich Obersteiner s zone is located at the point of entry of either between cranial nerves and the brain or spinal nerves and the spinal cord . This narrow zone identified visually where there is a transition regarding myelin production. As stated above, the Redlich Obersteiner s zone separates the CNS and PNS. Thus at this point, there is a transition from Schwann cell myelin meet to oligodendrocyte myelin. Of note, in cranial nerves this is often the place of neuro vascular compression syndromes such as trigeminal neuralgia. Category Nervous system de Redlich Obersteiner Zone ... more details
Multiple issues orphan October 2010 context December 2010 unreferenced October 2010 Caspr is a contactin associated protein . Caspr is part of the neurexin family of proteins. It lies in the paranodal section of the myelin sheath , between the Nodes of Ranvier containing Na channels, and K channels in the juxtaparanodal region. Its role is for myelin sheath attachment along with contactin laterally in a cis complex. In staining, it shows up as green with immunohistochemical steps, and along with VNa red shows a red green contrast to stain for defects in myelin sheath, and size of Nodes of Ranvier. In Western Blotting it has a predicted Molecular Weight around 156 kDa but due to a number of potential glycosylation sites, is 180kDa. Category Human proteins ... more details
Remyelination is a term for the re generation of the nerve nerve s myelin sheath , damaged in many diseases such as multiple sclerosis MS and the leukodystrophy leukodystrophies . Remyelination is a subject of active medical research . See also The Myelin Project External links http www.mssociety.org.uk research ms frontiers 2005 04 remyelination.html MS Society page on remyelination http discoverysedge.mayo.edu de07 4 neuro lucchinetti Mayo Clinic Repairing the Nervous System Multiple Sclerosis and Remyelination neuroanatomy stub Category Neuroanatomy cs Remyelinizace ... more details
Infobox neuron neuron name Oligodendrocyte precursor cell image neuron caption neuron location function neurotransmitter morphology afferents efferents NeuroLex Oligodendrocyte precursor cell NeuroLexID nifext 169 Code TerminologiaHistologica 2 00 06.2.01007 Latin cellula oligodendrocytoprogenetrix Oligodendrocyte precursor cell s in nervous tissue cells precede oligodendrocytes , and may also be able to generate neuron neurons and astrocyte astrocytes . The principal function of oligodendrocytes is to provide support to axon axons and to produce the Myelin sheath , which insulates and lowers the effective capacitance of axons. Myelin is 80 lipid and 20 protein and speeds the conduction of action potential s down the axon. Oligodendrocytes, unlike Schwann cell s of the PNS , form segments of myelin sheaths of numerous neuron s at once. The processes of a given oligodendrocyte wrap themselves around portions of the surrounding axons. As each process wraps itself around, it forms layers of myelin. Each process thus becomes a segment of the axon s myelin sheath. External links http www.neuinfo.org nif nifgwt.html?query 22Oligodendrocyte 20Precursor 20Cell 22 NIF Search Oligodendrocyte Precursor Cell via the Neuroscience Information Framework Human cell types derived primarily from ectoderm Category Nervous tissue cells Category Glial cells kr zh ... more details
Image Pons very high mag.jpg thumb right Micrograph of the pons using a H&E stain hematoxylin & eosin luxol fast blue stain. Luxol fast blue stain , abbreviated LFB stain and simply LFB , is a commonly used staining stain to observe myelin under light microscopy . It is the alcohol soluble counterpart of the water soluble alcian blue . The stain works via an acid base reaction with the base of the lipoprotein in myelin replacing the base of the dye and causing a colour change. Under the stain, myelin fibers appear blue, neuropil appears pink, and nerve cells appear purple. It is often combined with hematoxylin and eosin , which is abbreviated H E LFB , H&E LFB . See also H&E stain Bielschowsky stain References Sheehan D, Hrapchak B, Theory and practice of Histotechnology, 2nd ed,1980, pp. 262 264, Battelle Press, Ohio. Category Staining biology stub ... more details
Image Galactoceramide.png thumb 300px A galactocerebroside A galactocerebroside or galactosylceramide is a type of cerebroside consisting of a ceramide with a galactose residue at the 1 hydroxyl moiety. The galactose is cleaved by galactosylceramidase . Galactocerebroside is a marker for oligodendrocytes in the brain, whether or not they form myelin ref name http www.nature.com nature journal v274 n5673 abs 274813a0.html ref name http jcb.rupress.org content 101 3 1135.abstract . Additional Images gallery Image Sphingolipid.png Sphingolipid Image Glucose.png glucose gallery See also Globoid cell leukodystrophy Myelin References Reflist External links MeshName Galactocerebrosides https www.ebi.ac.uk chembldb index.php compound inspect CHEMBL110111 CHEMBL110111 http web.indstate.edu thcme mwking galactocerebroside.jpg image Sphingolipids Category Glycolipids biochemistry stub ca Galactosilceramida ... more details
saved book title Neuroscience subtitle An overview cover image Putamen.jpg cover color black bug Several articles contain tl Neuron map and similar templates. These do not have the elements dendrite, saxon, ... displayed at the correct place see http en.wikipedia.org w index.php?title Special Book&bookcmd render article&arttitle Brain&oldid 360540812&writer rl brain , for example . See http code.pediapress.com wiki ticket 759 bug 759 . Note that this only affects the downloadable PDF, the printed books do not have this problem. Neuroscience Societies American Society for Neurochemistry General Neuroscience Central nervous system Neurochemistry Neurotransmitter Dopamine Astrocytes Glial cell Oligodendrocytes Oligodendrocyte Myelin Myelin basic protein Demyelinating disease Neurons Axon Neuron Action potential Diseases Multiple sclerosis Anatomy Spinal cord Cerebellum Brain Category Wikipedia books on natural sciences Category Wikipedia books on biology Category Wikipedia books on medicine ... more details
A nerve tissue protein is a biological molecule related to the function and maintenance of normal nervous tissue . ref MeshName Nerve tissue proteins ref An example would include, for example, the generation of myelin which insulates and protects nerves. These are typically calcium binding proteins . References reflist Category Neurology biochem stub neuroscience stub Nerve tissue protein ... more details
Summary Non free use rationale Article Immortal Cities Children of the Nile Description Immortal Cities Children of the Nile cover art. Source From http www.metmuseum.org store images Z.cd.M8040.L.jpg Metmuseum . Portion Image shown in its entirety. Low resolution It is a low resolution image. Purpose Illustrates the entire subject of the article. Replaceability It s the official cover. No free alternative could possibly exist. other information Copyright owned by Tilted Mill Entertainment and Myelin Media . Licensing Non free game cover windows ... more details
orphan date September 2010 Status marmoratus is the presence in full term infants of basal nucleus lesion s resulting from acute total asphyxia . The lesions have a marbled appearance caused by neuron al loss and an overgrowth of myelin in the putamen , Caudate nucleus caudate , and thalamus . References http medical dictionary.thefreedictionary.com status marmoratus med stub Category Pediatrics pl Stan marmurkowaty ... more details
Nuclei colliculi superioris are groups of large cells in the middle gray layer of the superior colliculus and more laterally near the midbrain tegmentum. ref citebook author Riley HA year 1943 title An Atlas Of The Basal Ganglia, Brain Stem And Spinal Cord Based On Myelin Stained Material publisher Williams and Wilkins Co location Baltimore oclc 2830004645158 ref References Reflist External links More information at http braininfo.rprc.washington.edu centraldirectory.aspx?ID 1457 BrainInfo Categories Category Neuroanatomy neuroanatomy stub ... more details
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