orphan date February 2010 Gaspard Terrasson October 1680 &ndash 2 January 1752 was a French Oratorian , teaching humanities and afterwards philosophy, and later a well known preacher. Life Terrasson was born at Lyon . His oratorical talents were revealed at Troyes , 1711, on delivering the funeral oration of the Dauphin of France Dauphin , son of Louis XIV but he did not devote himself to preaching till after the death in 1723 of his brother Andr Terrasson , when he fulfilled several engagements which the latter had made. For five years he preached at Paris, and finally delivered a Lenten course in the Church of Notre Dame. He appealed repeatedly against the papal bull Unigenitus he was the anonymous author of twelve Lettres sur la justice chr tienne Paris, 1733 , in which, to support the Jansenists whom the bishops deprived of the sacraments, he endeavoured to prove the inutility of sacramental confession . This work was condemned by the faculty of theology at Paris 1 Sept., 1734 , and by the Archbishops of Sens and Embrun, as containing erroneous, schismatical and heretical assertions. Terrasson had to leave the Oratory and abandon preaching. He withdrew to the Diocese of Auxerre where the bishop, Charles de Caylus , a well known Jansenist, confided to him the care of Treigni . But he was soon arrested Oct., 1735 by the order of the king for his Jansenistic activities, and was confined during nine years either at Vincennes or with the Minims of Argenteuil . A belated retraction, the authenticity or sincerity of which has never been well established, was attributed to him. He was living in retirement with his family when he died at Paris. Works A volume of his discourses appeared at Utrecht in 1733, but the first real edition was at Paris in 1744 4 vols. . The sermons of the two brothers were reprinted by Migne in his Collection des orateurs sacr s , XXIX Paris, 1849 . References reflist Attribution Catholic wstitle Andr Terrasson The entry cites Cursay, M moires ... more details
Podophyllin is a resinous powder obtained by precipitating an alcoholic tincture of the rhizome of American Mayapple Podophyllum peltatum or Podophyllum emodi by means of water acidified with hydrochloric acid . It varies in color from grayish to bright yellow or greenish brown, the first named being the purest. It was commonly used against HPV induced genital wart s because it contains antiwart lignan s, although podofilox , a purified form of the main active ingredient, has become recommended due to its higher efficacy and safety. ref name PodofiloxAssessment cite journal author Longstaff E, von Krogh G title Condyloma eradication self therapy with 0.15 0.5 podophyllotoxin versus 20 25 podophyllin preparations an integrated safety assessment journal Regul. Toxicol. Pharmacol. volume 33 issue 2 pages 117 37 year 2001 month April pmid 11350195 doi 10.1006 rtph.2000.1446 url ref The powder is soluble in alcohol and strong solutions of alkali s, such as ammonia . Its composition is somewhat complex. There are certainly at least two resin s in the powder which is known officially as Podophylli resina , one of them being soluble and the other insoluble in ether. Each of these contains an active substance, which can be obtained in crystalline form, and is known as podophyllotoxin . It is soluble in alcohol, ether, chloroform and boiling water. Reactivity Alkalis decompose it into picro podophyllic acid and picro podophyllin, minute traces of both of which occur in a free state in the rhizome. The acid is inert, but picro podophyllin is the active agent. It is a crystalline body, soluble only in concentrated alcohol. Hence the inutility of the pharmacopeial tinctura podophylli, which cannot be diluted before administration. The properties of podophyllin resin vary with the reaction of the tissue with which it is in contact where this is acid the drug is inert, the picro podophyllin being precipitated. The resin does not affect the unbroken skin, but may be absorbed from a ... more details
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