onesource date November 2009 An Intergenic region IGR is a stretch of DNA sequences located between Gene cluster clusters of gene s that contain few or no genes. Occasionally some intergenic DNA acts to control genes nearby, but most of it has no currently known function. It is one of the DNA sequence s collectively referred to as junk DNA , though it is only one phenomenon labeled such and in scientific studies today, the term is less used. In humans, intergenic regions comprise a large percentage of the genome . This could also be where noncoding RNA s are located. Though little is known about them, they are thought to have regulatory functions. Inter genic regions are different from intra genic regions or introns , which are short, non coding regions that are found within genes, especially within the genes of eukaryotic organisms. Scientists have now artificially synthesized proteins from intergenic regions. ref http www.jbioleng.org content 3 1 2 ref Image Intergenic DNA.gif See also Exon Noncoding DNA Promoter biology References reflist citationstyle Category DNA genetics stub zh ... more details
Unreferenced stub auto yes date December 2009 Orphan date February 2009 Eukaryotic intergenic DNA is DNA located between functional genes on the eukaryotic chromosome . See also Eukaryotic chromosome fine structure Junk DNA Non coding DNA DEFAULTSORT Eukaryotic Intergenic Dna Genetics stub Category DNA ... more details
RRNA Ribosomal RNA rRNA intergenic spacer analysis RISA is a method of microbial community analysis that provides a means of comparing differing environments or treatment impacts without the bias imposed by culture dependent approaches. RISA involves PCR amplification of a region of the rRNA gene operon between the small 16S and large 23S subunits called the intergenic spacer region ISR. By using oligonucleotide primers targeted to conserved regions in the 16S and 23S genes, RISA fragments can be generated from most of the dominant bacteria in an environmental sample. While the majority of the rRNA operon serves a structural function, portions of the 16S 23S intergenic region can encode tRNAs depending on the bacterial species. However the taxonomic value of the ISR lies in the significant heterogeneity in both length and nucleotide sequence. In RISA, we attempt to exploit the length heterogeneity of the ISR, which has been shown to range between 150 and 1500 bp with the majority of the ISR lengths being between 150 and 500 bp. The resulting PCR product will be a mixture of fragments contributed by several dominant community members. This product is electrophoresed in a polyacrylamide gel , and the DNA is visualized following staining. The result is a complex banding pattern that provides a community specific profile, with each DNA band corresponding to a bacterial population on the original assemblage. References references Borneman, J. and E.W. Triplett. 1997. Molecular microbial diversity in soils from eastern Amazonia evidence for unusual microorganisms and microbial population shifts associated with deforestation. Appl. Environ. Microbiol. 63 2647 2653. Sigler, W.V. and J. Zeyer. 2002. Microbial diversity and activity along the forefields of two receding glaciers Microb. Ecol. 43 397 407. Sigler, W.V., S. Crivii, and J. Zeyer. 2002. Bacterial succession in glacial forefield soils characterized by community structure, activity and opportunistic growth dynamics. Microb ... more details
Infobox rfam Name iscR stability element image IscRS SS.png width caption Secondary structure of iscR stability element RNA Symbol iscRS AltSymbols Rfam RF01517 miRBase miRBase family RNA type Cis regulatory element Tax domain Enterobacteriales GO SO CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The IscR stability element is a conservation genetics conserved secondary structure found in the intergenic regions of iscRSUA polycistronic mRNA. This secondary structure prevents the degradation of the iscR mRNA . The iscRSUA operon encodes for the protein proteins required in iron sulfur cluster biosynthesis where the gene expression expression of this operon is regulated by RyhB RNA RhyB and iscR, a transcription repressor. ref name pmid12975324 Cite pmid 12975324 ref ref name pmid16199566 Cite pmid 16199566 ref ref name pmid12446632 Cite pmid 12446632 ref Under sufficient iron conditions RhyB binds to iscRSUA mRNA and promotes the degradation of the mRNA located downstream of iscR. Scanning the intergenic regions of this polycistronic mRNA and using Mfold software a secondary structure was predicted within the intergenic region between iscR and iscS and later confirmed by lead acetate probing. ref name pmid19407815 Cite pmid 19407815 ref Mutant Mutations that disrupt this secondary structure resulted in the degradation of iscR mRNA after RhyB binding. 3 Rapid Amplification of cDNA Ends RACE analysis of the iscR mRNA fragment identified the intergenic RNA at the 3 end. These results suggest that this intergenic RNA element acts as a iscR mRNA stability element by protecting iscR from exonuclease degradation. References reflist External links Rfam id RF01517 name iscR stability element Category RNA Category Gene expression Category Non coding RNA ... more details
PBB geneid 100302299 HOTAIRM1 HOX antisense intergenic RNA myeloid 1 is a long non coding RNA gene. In humans, it is located between the HOXA1 and HOXA2 genes. HOTAIRM1 is expressed in cells of a myeloid lineage, and may play a role in myeloid transcriptional regulation . ref name pmid19144990 cite journal author Zhang X, Lian Z, Padden C, et al. title A myelopoiesis associated regulatory intergenic noncoding RNA transcript within the human HOXA cluster journal Blood volume 113 issue 11 pages 2526 34 year 2009 month March pmid 19144990 pmc 2656274 doi 10.1182 blood 2008 06 162164 url ref See also Long noncoding RNA References reflist Category Non coding RNA ... more details
In molecular biology, Yar y ellow a chaete intergenic R NA is a long non coding RNA found in Drosophila . It is located within a neuronal gene cluster between the yellow and achaete genes. ref name pmid18704163 Cite pmid 18704163 ref ref name pmid21775470 Cite pmid 21775470 ref It is found in the cytoplasm of cells and is required for the regulation of sleep . ref name pmid21775470 Cite pmid 21775470 ref See also Long noncoding RNA References reflist 2 Category Non coding RNA ... more details
IGR may refer to Cataratas del Iguaz International Airport Iguassu International Airport serving Puerto Iguaz and the nearby falls IGR Iwate Ginga Railway in Iwate Prefecture, Japan Imperial Japanese Government Railways or, domestically, Imperial Government Railways of early 20th century Japan Indiana Guard Reserve Insect growth regulator , a chemical that disrupts the growth and or development of insects The Interessengemeinschaft f r Rundfunkschutzrechte IGR , a broadcasting IP rights interest group Zweikanalton IGR Stereo , a German standard for analogue TV stereo audio transmission claimed by the above organization. Intergenic region disambig fr IGR it IGR ja IGR ... more details
Orphan date February 2009 Transcripts of unknown function TUFs is the name that has been suggested for known RNA RNA transcripts of DNA whose function is unclear. Most TUFs are probably Non coding RNA ncRNAs , such as RNAi or snoRNA s, but could also represent a whole new class of ncRNA. ref name Gingeras cite journal last Gingeras first Thomas R. year 2007 title Origin of phenotypes Genes and transcripts journal Genome Research volume 17 issue 6 pages 682 690 doi 10.1101 gr.6525007 pmid 17567989 ref The DNA sequences for TUFs reside in the Intergenic region intergenic or intron ic regions of the genome , which is often called junk DNA . This currently makes up much of the human genome , although the percentage of the genome that falls under the TUFs category is likely to go down significantly as more progress is made towards understanding the many roles of RNA. Categories of TUFs Broadly speaking, TUFs can be classified into three categories ref name Gingeras br 1. TUFs that are complementary to Sense molecular biology sense transcripts of gene protein coding genes br 2. TUFs that are novel Protein isoform isoform transcripts of protein coding genes this can include pseudogene expressed pseudogenes br 3. TUFs that reside on the same strand as protein coding genes in the intronic region or entirely in the intergenic region Other information There are very few details known about TUFs, which is why the phrase even exists, but one thing that has been shown several times is that they are not very conserved between mice and humans. This could be due to a number of factors, including more recent evolution in the primate lineage or extensive post transcriptional modification of the RNA. ref name Gingeras References references DEFAULTSORT Transcript Of Unknown Function Category Molecular genetics Category RNA Category Non coding RNA ... more details
Linc may refer to Language Instruction for Newcomers to Canada , Canadian federal government language education programme Lincoln Financial Field , the home stadium of the Philadelphia Eagles of the National Football League Lincoln M. Alexander Parkway Expressway in Hamilton, Ontario , Canada Abraham Lincoln Lincoln, Abraham , 16th President of the United States LINC Laboratory Instrument Computer LINC 4GL Programming Language Linc Hayes, TV character on The Mod Squad played by Clarence Williams III MIT LINC , Learning International Networks Consortium LINC Linc Energy , Australian energy company the American Securitization Forum American Securitization Forum s ASF Loan Identification Number Code ASF LINC LINC Large Intergenic Non coding RNAs, a type of Long non coding RNA See also Library Information Network of Clackamas County LINCC Link disambiguation Linq Disambig ... more details
Risa may refer to Japanese given name nihongo Risa , is a feminine boyish Japanese given name People Risa Coda , a Japanese AV actress Risa Hayamizu , a Japanese voice actress Risa It , a Japanese manga artist Risa Junna , a Japanese actress Risa Kud , a Japanese model and actress Risa Niigaki , a member and leader of the Japanese pop group Morning Musume Risa Ohki , a Japanese vocalist Risa Shimamoto , a Japanese gravure idol Risa Wataya , a Japanese novelist Fictional characters Risa Harada , a character from the anime and manga series D.N.Angel Risa Koizumi, a character from the anime and manga series Lovely Complex Other uses Risa Star Trek , a fictional planet Radioiodinated serum albumin Recording Industry of South Africa Ribosomal Intergenic Spacer analysis Risa Clothing, a Danish clothing label See also lookfrom intitle Rise disambiguation Riza disambiguation disambig surname Category Japanese given names pl Risa ... more details
italic title taxobox name Pleioblastus image Pleioblastus gramineus1.jpg image caption Pleioblastus gramineus in cultivation at the Botanical Gardens Faculty of Science Osaka City University regnum Plantae unranked divisio Angiosperms unranked classis Monocots unranked ordo Commelinids ordo Poales familia Poaceae subfamilia Bambusoideae genus Pleioblastus genus authority Takenoshin Nakai Nakai Pleioblastus is a genus of monopodial bamboo . ref name Ohrnberger cite book last Ohrnberger first D. title The Bamboos of the World publisher Elsevier Science year 1999 pages 596 isbn 978 0444500205 ref Genetic research indicates that this genus may properly be part of the genus Arundinaria . ref name Zhuge Cite journal doi 10.1007 BF02856844 last Zhuge first Qiang coauthors Yu long Ding, Chen Xu, Hui yu Zou, Min ren Huang, and Ming xiu Wang title A preliminary analysis of phylogenetic relationships of Arundinaria and related genera based on nucleotide sequences of nrDNA ITS region and cpDNA trnL F intergenic spacer journal Journal of Forestry Research publisher Springer volume 16 issue 1 pages 5 8 year 2005 accessdate 2009 01 02 postscript None ref References reflist Category Bamboo genera Bamboo stub nl Pleioblastus ... more details
Refimprove date March 2009 A suppressor mutation is a mutation that counteracts the phenotype phenotypic effects of another mutation. There are several classes ref name Brock cite book author Madigan M, Martinko J editors title Brock Biology of Microorganisms edition 11th ed. publisher Prentice Hall year 2006 isbn 0 13 144329 1 ref mutation within the same gene e.g. second frameshift that occurs near the first one mutation within another gene extragenic mutation that restore the function of the original mutated gene that results in the production of a protein that replaces the mutated one intergenic mutation. References reflist External links http en.wikibooks.org wiki General Biology Genetics Mutation Mutation The mutations chapter of the WikiBooks General Biology textbook http www.gate.net rwms EvoMutations.html Examples of Beneficial Mutations http www.q pharm.com home contents drug d order form online services mutagenesis Software for Mutated Proteins Activity Prediction Category Evolutionary biology Category Molecular genetics Category Mutation Category Radiation health effects ja zh ... more details
Infobox rfam Name small Cajal body specific RNA 17 image RF00492.jpg width caption Predicted secondary structure and sequence conservation of SCARNA17 Symbol SCARNA17 AltSymbols snoU12 22 Rfam RF00492 miRBase miRBase family RNA type Gene Small nuclear RNA snRNA Small nucleolar RNA snoRNA Small Cajal body specific RNA scaRNA Tax domain Eukaryota GO GO 0006396 GO 0015030 GO 0005730 SO SO 0000275 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData Small Cajal body specific RNA 17 also known as U12 22 scaRNA is a type of small nuclear RNA which localises to the Cajal body cajal bodies and proposed to guide the modification of RNA polymerase II transcribed spliceosome spliceosomal RNAs U1 spliceosomal RNA U1 , U2 spliceosomal RNA U2 , U4 spliceosomal RNA U4 , U5 spliceosomal RNA U5 and U12 minor spliceosomal RNA U12 . ref name Tycowski2004 Cite pmid 15556860 ref ref name Lestrade2006 Cite pmid 16381836 ref The complete human U12 22 U4 8 scaRNA is composed of two tandem SnoRNA C.2FD box C D box domains termed U12 22 and U4 8 . The Directionality molecular biology 5 and 3 C D domains are predicted to guide the 2 O ribose methylation of residue U22 in U12 and residue C8 in U4 snRNAs respectively. ref name Tycowski2004 This family includes only the 5 C D box domain U12 22 as the 3 C D box is represented by Small Cajal body specific RNA 18 . The 3 C D domain U4 8 was also cloned previously by Darzacq and called U91. ref name Darxacq2002 Cite pmid 12032087 ref Both the doublet U12 22 U4 8 and singlet U4 8 forms of this snRNA have been purified from HeLa cells . ref name Tycowski2004 The doublet form U12 22 U4 8 has been shown to localise to the nucleoplasm and is proposed to reside in the Cajal bodies whereas the U4 8 single domain appears to accumulate in the nucleolus . ref name Tycowski2004 In humans the genomic location of U12 88 U4 8 is Intergenic region intergenic and the purified transcript has been shown to possess a 5 cap methylated ... more details
DISPLAYTITLE Bacillus subtilis BSR sRNAs In a screen of the Bacillus subtilis genome for genes encoding ncRNA ncRNAs , Saito et al. focused on 123 intergenic regions IGRs over 500 bp in length, the authors analyzed expression from these regions. Seven IGRs termed bsrC, bsrD, bsrE, bsrF, bsrG, bsrH and bsrI expressed RNAs smaller than 380 nt. All the bacterial small RNA small RNAs except BsrD RNA were expressed in transformed Escherichia coli cells harboring a plasmid with PCR amplified IGRs of B. subtilis, indicating that their own promoters independently express small RNAs. Under non stressed condition, depletion of the genes for the small RNAs did not affect growth. Although their functions are unknown, gene expression profiles at several time points showed that most of the genes except for bsrD were expressed during the vegetative phase 4 6 h , but undetectable during the stationary phase 8 h . Mapping the 5 ends of the 6 small RNAs revealed that the genes for BsrE, BsrF, BsrG, BsrH, and BsrI RNAs are preceded by a recognition site for Sigma factor RNA polymerase sigma factor &sigma sup A sup . ref name pmid18948176 cite journal author Saito S, Kakeshita H, Nakamura K title Novel small RNA encoding genes in the intergenic regions of Bacillus subtilis. journal Gene volume 428 issue 1 2 pages 2 8 year 2008 pmid 18948176 doi 10.1016 j.gene.2008.09.024 ref See also Bacterial small RNA Mycobacterium tuberculosis sRNA Mycobacterium tuberculosis sRNA C. elegans small RNAs Caenorhabditis elegans small RNAs Escherichia coli sRNA Escherichia coli sRNA Pseudomonas sRNA Pseudomonas sRNA References reflist Navbox name hide the gallery title Gallery of secondary structure images titlestyle background e7dcc3 state autocollapse list1 Gallery lines 5 Image BsrC secondary structure.jpg BsrC Seconday structre taken from the http rfam.sanger.ac.uk Rfam database. Family http rfam.sanger.ac.uk family RF01410 RF01410 Image BsrF secondary structure.jpg BsrF Seconday structre taken from ... more details
Italictitle taxobox name Aphanes image Aphanes arvensis kz1.jpg image caption Aphanes arvensis regnum Plant ae unranked divisio Angiosperms unranked classis Eudicots unranked ordo Rosids ordo Rosales familia Rosaceae subfamilia Rosoideae genus Aphanes genus authority Carolus Linnaeus L. subdivision ranks Species subdivision center 10 20, See text center Aphanes Parsley piert is a genus in the rose family, Rosaceae , native to Europe , Asia and Australia . A study from 2003 see Rosoideae indicates that Aphanes may belong to the genus Alchemilla , commonly called Lady s mantle. ref cite journal doi 10.1007 BF03030787 title Phylogeny of korean rubus rosaceae based on its nrDNA and trnL F intergenic region cpdna year 2006 last1 Yang first1 Ji Young last2 Pak first2 Jae Hong journal Journal of Plant Biology volume 49 pages 44 ref They are slender, annual prostrate herb s, much branched with deeply lobed Leaf leaves , pilose covered with soft hair and on short Petiole botany petiole s. The tiny green to yellow flower s without petal s grow in clusters in the denticulate leaflike stipule s. Selected species Aphanes arvensis Field Parsley piert, Western Lady s mantle, Parsley Breakstone Aphanes australiana Australian Piert Aphanes cotopaxiensis Aphanes australis synonymy syn. A. inexspectata , A. microcarpa Slender Parsley piert Aphanes occidentalis Dew Cup Lady s Mantel References reflist Category Aphanes Category Flora of Asia Category Flora of Europe Category Medicinal plants Category Demulcents ca Aphanes de Ackerfrauenmantel es Aphanes hsb R lny i manc lt Ma uol pl Skrytek pt Aphanes sv Jungfrukamssl ktet ... more details
italic title taxobox name Xylomelum image Xylomelum pyriforme.jpg image caption Xylomelum pyriforme regnum Plantae unranked divisio Angiosperms unranked classis Eudicots ordo Proteales familia Proteaceae genus Xylomelum genus authority James Edward Smith Sm. subdivision ranks Species subdivision Xylomelum angustifolium br Xylomelum benthamii br Xylomelum cunninghamianum br Xylomelum occidentale br Xylomelum pyriforme br Xylomelum scottianum Xylomelum is a genus of six species in the plant family Proteaceae . They are native to Australia , growing in the form of tall shrub s and tree s. The genus includes at least two species with the common name woody pear , Xylomelum pyriforme in the eastern states of Australia , and Xylomelum occidentale in Western Australia . Fruits The fruits of Xylomelum are in the form of woody pears. When dried, these pears split down a central division, resulting in two halves. These pears are thought to have evolved primarily as a defense against seed predation. However, these woody fruits also provide protection of the seeds from fire. It is therefore likely that this characteristic was reselected in evolution as fire became increasingly important. Classification Recent molecular studies have Xylomelum paired as a sister clade with Lambertia . References Hoot, S.B. and Douglas, A.W. Phylogeny of Proteaceae based on atpB and atpB rbcL intergenic spacer region sequences. Austral. Syst. Bot. 11 1998 , 301 320 Wikispecies Xylomelum Category Proteaceae genera Category Proteales of Australia Category Trees of Australia tree stub proteaceae stub Australia eudicot stub az Xylomelum es Xylomelum fr Xylomelum pt Xylomelum ... more details
Rfam box acc RF00120 description C0343 RNA abbreviation C0343 avg length 74.80 avg identity 88.00 type Gene sRNA se Hershberg R ss Predicted PFOLD release 10.0 The C0343 RNA is a bacterial non coding RNA of 74 nucleotides in length that is found between the ydaN and dbpA gene s in the genomes of Escherichia coli and Shigella flexneri , Salmonella enterica and Salmonella typhimurium . This ncRNA was originally identified in E.coli using microarray high density oligonucleotide probe arrays microarray ref name pmid12202758 cite journal author Tjaden B, Saxena RM, Stolyar S, Haynor DR, Kolker E, Rosenow C title Transcriptome analysis of Escherichia coli using high density oligonucleotide probe arrays journal Nucleic Acids Res. volume 30 issue 17 pages 3732 8 year 2002 pmid 12202758 doi 10.1093 nar gkf505 pmc 137427 ref . The function of this ncRNA is unknown. FnrS RNA was later found to be transcription genetics transcribed from the same intergenic region as C0343 RNA. ref cite journal author Durand S, Storz G title Reprogramming of anaerobic metabolism by the FnrS small RNA journal Mol. Microbiol. volume 75 issue 5 pages 1215 31 year 2010 month March pmid 20070527 pmc 2941437 doi 10.1111 j.1365 2958.2010.07044.x url http www3.interscience.wiley.com resolve openurl?genre article&sid nlm pubmed&issn 0950 382X&date 2010&volume 75&issue 5&spage 1215 accessdate 2010 08 04 ref See also C0299 RNA C0465 RNA C0719 RNA References references External links Rfam id RF00120 name C0343 RNA DEFAULTSORT C0343 Rna Category Non coding RNA molecular cell biology stub ... more details
lowercase Infobox rfam Name ctRNA image RF00489.jpg width caption Predicted secondary structure and sequence conservation of ctRNA p42d Symbol ctRNA p42d AltSymbols Rfam RF00489 miRBase miRBase family RNA type Gene Antisense RNA antisense Tax domain Bacteria GO SO SO 0000644 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData In molecular biology ctRNA counter transcribed RNA is a plasmid encoded noncoding RNA that binds to the mRNA of repB and causes translation genetics translational inhibition. ref name Ven03 cite journal last Venkova Canova first T coauthors Patek M, Nesvera J year 2003 title Control of rep gene expression in plasmid pGA1 from Corynebacterium glutamicum journal J Bacteriol volume 185 pages 2402&ndash 2409 pmid 12670963 doi 10.1128 JB.185.8.2402 2409.2003 issue 8 pmc 152619 ref ctRNA is encoded by plasmids and functions in rolling circle replication to maintain a low copy number. In Corynebacterium Corynebacterium glutamicum , it achieves this by antisense pairing with the mRNA of RepB, a self replication replication initiation protein. ref name Ven03 In Enterococcus faecium the plasmid pJB01 contains three open reading frames, copA, repB, and repC. The pJB01 ctRNA is coded on the opposite strand from the copA repB intergenic region and partially overlaps an atypical ribosome binding site for repB. ref name pmid18511887 cite journal author Kim SW, Jeong IS, Jeong EJ, et al. title The terminal and internal hairpin loops of the ctRNA of plasmid pJB01 play critical roles in regulating copy number journal Mol. Cells volume 26 issue 1 pages 26 33 year 2008 month July pmid 18511887 doi url ref See also S element References references External links Rfam id RF00236 name ctRNA pGA1 Rfam id RF00489 name ctRNA p42d Rfam id RF00238 name ctRNA pND324 Rfam id RF00242 name ctRNA pT181 Category Antisense RNA molecular cell biology stub ... more details
Infobox rfam Name SraC RyeA RNA image RF00101.jpg width caption Predicted secondary structure and sequence conservation of SraC RyeA Symbol SraC RyeA AltSymbols Rfam RF00101 miRBase miRBase family RNA type Gene Bacterial small RNA sRNA Tax domain Bacteria GO SO SO 0000655 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The SraC RyeA RNA is a non coding RNA that was discovered in E. coli during two large scale screens for RNAs. ref cite journal last Argaman first L coauthors Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S year 2001 title Novel small RNA encoding genes in the intergenic regions of Escherichia coli journal Curr Biol volume 11 pages 941&ndash 950 pmid 11448770 doi 10.1016 S0960 9822 01 00270 6 issue 12 ref ref cite journal last Wassarman first KM coauthors Repoila F, Rosenow C, Storz G, Gottesman S year 2001 title Identification of novel small RNAs using comparative genomics and microarrays journal Genes Dev volume 15 pages 1637&ndash 1651 pmid 11445539 doi 10.1101 gad.901001 issue 13 pmc 312727 ref The function of this RNA is currently unknown. This RNA overlaps the RyeB RNA on the opposite strand suggesting that the two RNAs may act in a concerted manner. References reflist 1 External links Rfam id RF00101 name SraC RyeA RNA molecular cell biology stub Category Non coding RNA ... more details
Infobox rfam Name SraB RNA image RF00077.jpg width caption Predicted secondary structure and sequence conservation of SraB Symbol SraB AltSymbols sraB Rfam RF00077 miRBase miRBase family RNA type Gene Bacterial small RNA sRNA Tax domain Bacteria GO SO SO 0000655 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The SraB RNA is a small non coding RNA discovered in E. coli during a large scale experimental screen ref name ref1 cite journal last Argaman first L coauthors Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S year 2001 title Novel small RNA encoding genes in the intergenic regions of Escherichia coli journal Curr Biol volume 11 pages 941&ndash 950 pmid 11448770 doi 10.1016 S0960 9822 01 00270 6 issue 12 ref . The 14 novel RNAs discovered were named sra for s mall R N A , examples include SraC RyeA RNA SraC , SraD RNA SraD and SraG RNA SraG . ref name ref1 This ncRNA was found to be expressed only in stationary phase ref name ref1 . The exact function of this RNA is unknown but it has been shown to affect survival of Salmonella enterica to antibiotic administration in egg albumin . ref name pmid21268901 cite journal author Jiang H, Cao M, Cao X, Gu H, Zeng K title sRNA sraB regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen language Chinese journal Wei Sheng Wu Xue Bao volume 50 issue 11 pages 1537 44 year 2010 month November pmid 21268901 doi url ref The authors suggest this may be due to SraB regulating a response to components in albumin. See Also Escherichia coli sRNA References reflist 1 External links Rfam id RF00077 name SraB RNA Category Non coding RNA molecular cell biology stub ... more details
Infobox rfam Name SraG RNA image RF00082.jpg width caption Predicted secondary structure and sequence conservation of SraG Symbol SraG AltSymbols Rfam RF00082 miRBase miRBase family RNA type Gene Bacterial small RNA sRNA Tax domain Bacteria GO SO SO 0000655 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData SraG small RNA G is a is a small non coding RNA ncRNA . It is the functional product of a gene which is not translated into protein . This ncRNA was discovered in the bacteria Escherichia coli during a large scale computational screen for transcription signals and genomic features of known small RNA encoding genes. ref name pmid11448770 cite journal author Argaman L, Hershberg R, Vogel J, et al. title Novel small RNA encoding genes in the intergenic regions of Escherichia coli journal Curr. Biol. volume 11 issue 12 pages 941 50 year 2001 pmid 11448770 doi 10.1016 S0960 9822 01 00270 6 ref During this screen 14 novel ncRNA genes were identified, including GlmZ RNA GlmZ , SraB RNA SraB , SraC RyeA RNA SraC and SraD RNA SraD . ref name pmid11448770 The expression of SraG was experimentally confirmed by Northern blotting which also indicated this RNA undergoes specific cleavage processing. ref name pmid11448770 The function of this RNA is unknown. References references External links Rfam id RF00082 name SraG RNA Category Non coding RNA molecular cell biology stub ... more details
Infobox rfam Name yybP ykoY leader image RF00080.jpg width caption Predicted secondary structure and sequence conservation of yybP ykoY Symbol yybP ykoY AltSymbols SraF Rfam RF00080 miRBase miRBase family RNA type Cis regulatory element Cis reg Tax domain Bacteria GO SO SO 0000233 CAS number EntrezGene HGNCid OMIM PDB RefSeq Chromosome Arm Band LocusSupplementaryData The yybP ykoY leader Cis regulatory element RNA element was originally discovered in E. coli during a large scale screen and was named SraF. ref name Argaman cite journal last Argaman first L coauthors Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S year 2001 title Novel small RNA encoding genes in the intergenic regions of Escherichia coli journal Curr Biol volume 11 pages 941&ndash 950 pmid 11448770 doi 10.1016 S0960 9822 01 00270 6 issue 12 ref This family was later found to exist Upstream molecular biology upstream of related families of protein genes in many bacteria, including the yybP and ykoY genes in B. subtilis . The specific functions of these proteins are unknown, but this structured RNA element may be involved in their genetic regulation as a riboswitch . ref name Barrik cite journal last Barrick first JE coauthors Corbino KA, Winkler WC, Nahvi A, Mandal M, Collins J, Lee M, Roth A, Sudarsan N, Jona I, Wickiser JK, Breaker RR year 2004 title New RNA motifs suggest an expanded scope for riboswitches in bacterial genetic control journal Proc Natl Acad Sci USA volume 101 pages 6421&ndash 6426 pmid 15096624 doi 10.1073 pnas.0308014101 issue 17 pmc 404060 ref References reflist 1 External links Rfam id RF00080 name yybP ykoY leader Category Cis regulatory RNA elements molecular cell biology stub ... more details
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