Infobox disease Name Thyroiditis Image Illu thyroid parathyroid.jpg Caption Above shows two parts of the thyroid that could potentially be affected if diagnosed with thyroiditis. DiseasesDB 13095 ICD10 ... Thyroiditis is the inflammation of the thyroid gland . The thyroid gland is located on the front ... Thyroiditis is a group of disorders that all cause thyroidal inflammation. Forms of the disease are Hashimoto s thyroiditis , the most commom cause of hypothyroidism in the US, postpartum thyroiditis , subacute thyroiditis , silent thyroiditis , drug induced thyroiditis , radiation induced thyroiditis , and acute thyroiditis . ref Thyroiditis. www.thyroid.org. 2005. American Thyroid Association ..., conditions and risks. Symptoms There are many different symptoms for thyroiditis, none of which are exclusively limited to this disease. Many of the signs imitate symptoms of other diseases, so thyroiditis ... of thyroiditis, one may start to see puffiness around the eyes, slowing of the heart rate, a drop ... cause both conditions, but thyrotoxicosis is the term used for with thyroiditis since the thyroid gland is not overactive, as in the case of hyperthyroidism. ref Thyroiditis. www.thyroid.org. ... . ref ref name AmerAcad Thyroiditis. Familydoctor.Org. 2007. American Academy of Family Physicians ... Thyroiditis is generally caused by an attack on the thyroid, resulting in inflammation and damage ... that attack the thyroid are what causes most types of thyroiditis. It can also be caused by an infection ... people make thyroid antibodies, and thyroiditis can be considered an autoimmune disease, because .... Medicine.Net. 8 Sept. 2007. 9 Mar. 2008 http www.medicinenet.com hashimotos thyroiditis article.htm . ref Some drugs, such as interferon and amiodarone , can also cause thyroiditis because they have ... thyroiditis is first for a physician to palpate the thyroid gland during a physical examination ... tests also help to determine the kind of thyroiditis and to see how much thyroid stimulating hormone ... more details
Infobox disease Name Subacute thyroiditis Image Caption DiseasesDB ICD10 ICD10 E 06 1 e 00 ICD9 ICD9 245.1 ICDO OMIM MedlinePlus eMedicineSubj article eMedicineTopic 125648 MeshID D013968 Subacute thyroiditis is a form of thyroiditis that can be a cause of both thyrotoxicosis and hypothyroidism . ref name urlSubacute Thyroiditis Overview eMedicine Endocrinology Cite web url http emedicine.medscape.com article 125648 overview title Subacute Thyroiditis Overview eMedicine Endocrinology format work accessdate ref It is uncommon and can affect individuals of both sexes and all ages. It manifests as a sudden and painful enlargement of the thyroid gland accompanied with fever, malaise and muscle aches. Some have suggested that its cause might be viral in origin. Types include De Quervain s thyroiditis Subacute lymphocytic thyroiditis Postpartum thyroiditis Palpation thyroiditis References Reflist Endocrine pathology Endocrine disease stub Category Thyroid disease ru ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB ICD10 ICD10 E 06 3 e 00 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013967 Autoimmune thyroiditis is a form of thyroiditis associated with an autoimmune disease where the body treats the thyroid gland and sometimes the hormones it produces as foreign bodies, therefore rejecting and attacking both. Symptoms Causes Treatment Thyroid hormone supplementation may help with symptoms and prevent further conditions like goitre and thyroid gland failure from happening. Consequences Goiter may result from Autoimmune Thyroiditis as a result of an increase in thyroid gland size. As well, the thyroid s ability to produce hormones for the body becomes impaired. Hypothyroidism can develop from the condition. Types It can refer to Hashimoto s thyroiditis Postpartum thyroiditis endocrine disease stub Endocrine pathology Category Thyroid disease ... more details
Infobox disease Name Ord s disease Image Caption DiseasesDB 34307 ICD10 ICD10 E 06 5 e 00 ICD9 ICD9 245.8 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013967 Ord s thyroiditis is a common form of thyroiditis , an autoimmune disease where the body s own antibody antibodies fight the cell biology cell s of the thyroid . It is named after the physician, William Miller Ord , who first described it in 1877 and again in 1888 . It is more common among women than men. Pathophysiology Physiologically, antibody antibodies to thyroid peroxidase and or thyroglobulin cause gradual destruction of Thyroid follicle follicle s in the thyroid gland. Accordingly, the disease can be detected clinically by looking for these antibodies in the blood. It is also characterised by invasion of the thyroid tissue by leukocytes , chiefly T lymphocytes. Ord s thyroiditis usually results in hypothyroidism . Transient hyperthyroidism hyperthyroid states in the acute phase, a common observation in Hashimoto s thyroiditis, are rare in Ord s disease. Clinical signs Symptoms of Ord s thyroiditis include symptoms of hypothyroidism and atrophy of the thyroid gland. Therapy Treatment is as with hypothyroidism , daily thyroxine T4 and or triiodothyronine T3 . Epidemiology Outside Europe a goitrous form of autoimmune thyroiditis Hashimoto s Thyroiditis is more common than Ord s disease. See also Thyroiditis Hypothyroidism Hashimoto s thyroiditis References Davies, T. F. 2003 , Ord Hashimoto s Disease Renaming a Common Disorder Again. Thyroid 13 4 317. PMID 12820593. Williams D. 2003 , Hashimoto s and Ord s diseases. Thyroid. 13 12 1189. PMID 14751044 DEFAULTSORT Ord s Thyroiditis Category Autoimmune diseases Category Thyroid disease de Ord Thyreoiditis ... more details
Infobox disease Name Riedel& 39 s thyroiditis Image Caption DiseasesDB 11590 ICD10 ICD10 E 06 5 e 00 ICD9 ICD9 245.3 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 2036 MeshID Riedel s thyroiditis , also called Riedel s struma is a chronic form of thyroiditis . It is believed to be a form of autoimmune thyroiditis . ref DorlandsDict eight 000108742 autoimmune thyroiditis ref Pathophysiology Riedel s thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule. Then invades to cerebellum, ventricles, subarachnoid space. This invasion makes whole body look like big collagenous thyroid gland. ref name pmid17603227 Cite journal author Cho MH, Kim CS, Park JS, et al. title Riedel s thyroiditis in a patient with recurrent subacute thyroiditis a case report and review of the literature journal Endocr. J. volume 54 issue 4 pages 559 62 year 2007 month August pmid 17603227 doi 10.1507 endocrj.K06 186 url http joi.jlc.jst.go.jp JST.JSTAGE endocrj K06 186?from PubMed format &ndash sup http scholar.google.co.uk scholar?hl en&lr &q intitle 3ARiedel 27s thyroiditis in a patient with recurrent subacute thyroiditis 3A a case report and review of the literature&as publication Endocr. J.&as ylo 2007&as yhi 2007&btnG Search Scholar search sup Dead link date April 2009 ref This makes the thyroid gland stone hard and fixed to adjacent structures. The inflammatory process infiltrates muscles and causes symptoms of tracheal compression. Surgical treatment is required to relieve tracheal or esophageal obstruction. A shared mechanism with retroperitoneal fibrosis and sclerosing ... s thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis diseases with one pathogenesis ... gut.34.5.714 url http gut.bmj.com cgi pmidlookup?view long&pmid 8504980 ref Prevalence Riedel s thyroiditis ... N, Kusic Z title Riedel s thyroiditis treated with tamoxifen journal Croat. Med. J. volume 44 issue ... more details
. Of those women who experience hypothyroidism associated with postpartum thyroiditis, one in five will develop permanent hypothyroidism requiring life long treatment. Postpartum thyroiditis is believed ... is a subacute lymphocytic thyroiditis . The process is normally self limiting, but when conventional ... thyroiditis is a member of the group of thyroiditis conditions known as resolving thyroiditis ... months postpartum ref name Stagnaro cite journal last Stagnaro Green first A. title Postpartum thyroiditis ... is not considered postpartum thyroiditis ref name Stagnaro . Women who test positive for thyroid ..., F., McMillan, J.M. title Postpartum psychosis and postpartum thyroiditis journal Psychoneuroendocrinology ... . Prevalence Worldwide reporting of postpartum thyroiditis cases is highly varied. This variation may ... Premawardhana, L.D.K.E., Parkes, A.B., & Lazarus, J.H. 2004 . Thyroiditis, postpartum. In Editor ..., L. D. K. E., Parkes, A. B., & Lazarus, J. H. 2004 . Thyroiditis, postpartum. In Editor in Chief ... of postpartum thyroiditis than non diabetic women in the same region ref name Stagnaro ..., A. 2000 . Recognizing, understanding, and treating postpartum thyroiditis. Endocrinology & Metabolism ... s thyroiditis T cell changes increased CD4 CD8 ratio Diagnosis This condition is commonly undiagnosed ... more details
Palpation thyroiditis refers to the development of thyroid inflammation due to mechanical damage to thyroid follicles . This can occur by vigorous repeated palpation as with thyroid examination or surgical manipulation as can occur with radical neck dissection . It is a type of subacute thyroiditis . Pathology shows multifocal granulomatous folliculitis. T cell s predominate compared to B cell s. There may be initial transient hyperthyroidism due to leakage of preformed thyroid hormone in blood. ref cite pmid 1242618 ref ref name Becker2001 citation last Becker first Kenneth L. year 2001 title Principles and practice of endocrinology and metabolism, Page 957 edition 3 publisher Lippincott Williams & Wilkins isbn 9780781717502 page 461 url http books.google.co.uk books?id FVfzRvaucq8C&pg PA461&ved 0CCkQ6AEwAA v onepage&q&f false editor1 Kenneth L. Becker ref References Reflist Endocrine pathology Endocrine disease stub Category Thyroid disease ... more details
Infobox disease Name Hashimoto s thyroiditis Image Hashimoto 4er.jpg Caption Histology DiseasesDB 5649 ... 949 MeshID D050031 Hashimoto s thyroiditis or chronic lymphocytic thyroiditis is an autoimmune disease ... Hakaru in Germany in 1912. Signs and symptoms Hashimoto s thyroiditis very often results in hypothyroidism ... . It is associated with non Hodgkin lymphoma . Symptoms of Hashimoto s thyroiditis include ... loss. The thyroid gland may become firm, large, and lobulated in Hashimoto s thyroiditis, but changes ... infiltration and fibrosis rather than tissue hypertrophy . Diagnosis Hashimoto s thyroiditis is often ... risk of 3 in the UK. In addition Hashimoto s thyroiditis may be associated with CTLA 4 gene since ... may also have these antibodies without developing Hashimoto s thyroiditis. Treatment Hypothyroidism caused by Hashimoto s Thyroiditis is treated with thyroid hormone replacement agents such as levothyroxine .... In the event that hypothyroidism is caused by Hashimoto s Thyroiditis, it is recommended that the TSH ... levels and symptoms. Preliminary studies have suggested a correlation between Hashimoto s Thyroiditis and Celiac s disease ref cite web title Connection Found Between Celiac Disease and Hashimoto s Thyroiditis ... Thyroiditis Page1.html ref . While it has not been rigorously explored, there is anecdotal evidence ... thyroiditis in patients with celiac disease url http www.ncbi.nlm.nih.gov pubmed 22126672 ref . While there was a higher occurrence of thyroiditis found amongst the Celiac group, there was no reduction ... reports. Prognosis If untreated for an extended period, Hashimoto s thyroiditis may lead to muscle failure, including possible heart failure. An extremely rare condition associated with the thyroiditis ... s thyroiditis can disrupt growth in children and adolescents and therefore requires close growth ... for the whole sentence date June 2011 In European countries, an atrophic form of autoimmune thyroiditis Ord s thyroiditis is more common than Hashimoto s thyroiditis. History Image .jpg thumb ... more details
Subacute lymphocytic thyroiditis is a form of thyroiditis that is also known as silent thyroiditis or painless thyroiditis .Subacute lymphocytic thyroiditis may occur at any age and is more common in females. A variant of subacute lymphocytic thyroiditis occurs postpartum postpartum thyroiditis. Both these entities can be considered subtypes of Hashimoto s thyroiditis and have an autoimmune basis. Anti thyroid antibodies are common in all three and the underlying histology is similar. ref name afp http www.aafp.org afp 20000215 1047.html Thyroiditis Differential Diagnosis and Management , American Family Physician,February 15, 2000 ref ref DorlandsDict eight 000108754 Subacute lymphocytic thyroiditis ref Symptoms Subacute lymphocytic thyroiditis features a small Goitre goiter without tenderness. This condition tends to have a phase of hyperthyroidism followed by a return to a euthyroid state, and then a phase of hypothyroidism , followed again by a return to the euthyroid state. The time span of each phase can vary however, each phase usually lasts 2 3 months. ref name afp Diagnosis Subacute lymphocytic thyroiditis can only be diagnosed correctly by taking a radioactive iodine uptake test , or RAIU test. ref name afp ref name raiu http www.webmd.com a to z guides radioactive iodine uptake test Description of Radioactive Iodine Uptake Test, WebMD.com, August 14, 2008 ref During the hyperthyroid phase, iodine uptake is suppressed, while during the hypothyroid phase, uptake is increased. ref name nih http www.nlm.nih.gov MEDLINEPLUS ency article 000388.htm NIH Medline Plus ref This situation contrasts greatly with the elevated iodine uptake found in patients with Graves disease . ref name afp Treatment Treatment is based on symptoms. Beta blockers relieve rapid heart rate and excessive sweating during the hyperthyroid phase. ref name nih References reflist Endocrine pathology Category Thyroid disease it Tiroidite silente ja ru ... more details
Infobox Disease Name PAGENAME Image Caption DiseasesDB 34307 ICD10 ICD10 E 06 0 e 00 ICD9 ICD9 245.0 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D013969 Acute infectious thyroiditis is a rare form of thyroiditis ref name urlThyroiditis Differential Diagnosis and Management February 15, 2000 American Academy of Family Physicians cite web url http www.aafp.org afp 20000215 1047.html title Thyroiditis Differential Diagnosis and Management February 15, 2000 American Academy of Family Physicians format work accessdate ref directly caused by an infection usually bacterial . Although acute infection is rarely present in clinically significant thyroiditis, many other types of thyroiditis have a granulomatous or autoimmune pathophysiology, indicating that there may be a relationship between the condition and a prior infection. References reflist endocrine disease stub Endocrine pathology Category Thyroid disease ru ... more details
Infobox Disease Name De Quervain s thyroiditis Image Caption DiseasesDB 3474 ICD10 ICD10 E 06 1 e 00 ICD9 ICD9 245.1 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 534 MeshID D013968 de Quervain s thyroiditis , can also be known as subacute granulomatous thyroiditis or Giant Cell Thyroiditis . Males and females of all ages are affected. It is a member of the group of thyroiditis conditions known as resolving thyroiditis . Terminology It is sometimes called subacute thyroiditis , ref name pmid9379217 cite journal author Topuzovic N, Smoje J, Karner I title The therapeutic approach in subacute de Quervain s thyroiditis journal J. Nucl. Med. volume 38 issue 10 pages 1665 year 1997 month October pmid 9379217 doi url http jnm.snmjournals.org cgi pmidlookup?view long&pmid 9379217 ref but there is another form of subacute thyroiditis, subacute lymphocytic thyroiditis . It is also sometimes called painful subacute thyroiditis . ref name pmid1404465 cite journal author Peter SA title Painful subacute thyroiditis de Quervain s thyroiditis journal J Natl Med Assoc volume 84 issue 10 pages 877 9 year 1992 month October pmid 1404465 pmc 2571803 doi url ref This is in contrast to subacute lymphocytic thyroiditis, which is also sometimes called painless thyroiditis . Causes Some cases may be virus viral in origin, perhaps preceded by an upper respiratory tract infection . Viral causes include Coxsackie virus , mumps and adenoviruses . Some cases develop postpartum. Presentation Patients will experience a hyperthyroid period as the cellular lining of colloid spaces fails, allowing abundant colloid into the circulation, with neck pain and fever. Patients typically then become hypothyroid ... uptake and scan can be helpful, since subacute thyroiditis will result in decreased isotope uptake ... thyroiditis is usually self limited and is not treated with radioiodine. Treatment Treatment is beta ... Endocrine pathology DEFAULTSORT De Quervain s Thyroiditis Category Thyroid disease endocrine ... more details
Radiation induced thyroiditis is a form of painful, acute thyroiditis resulting from radioactive therapy to treat hyperthyroidism or from radiation to treat head and neck cancer or lymphoma. It affects 1 of those who have received radioactive iodine I 131 therapy for Graves Disease , typically presenting between 5 and 10 days after the procedure. ref http www.aafp.org afp 2006 0515 p1769.html ref Stored Triiodothyronine T sub 3 sub and Thyroxine T sub 4 sub are released as rapid destruction of thyroid tissue occurs, resulting in pain, tenderness, and exacerbation of hyperthyroidism. References references Category Cancer treatments Category Thyroid disease Category Radiation health effects ... more details
De Quervain may refer to DeQuervain s syndrome as a form of tendinosis De Quervain s thyroiditis disambig Long comment to avoid being listed on short pages it De Quervain ... more details
Euthyroid is the state of having normal thyroid gland function. Examples of a nonfunctioning thyroid gland may be hypothyroidism , hyperthyroidism , or thyroiditis . ref name mn http www.medterms.com script main art.asp?articlekey 11352 Definition of Euthyroid , MedicineNet.com, July 7, 2002. ref ref name mw http www.merriam webster.com medical euthyroid Definition of Euthyroid , Merriam Webster Medical Dictionary ref References reflist Category Thyroid disease med stub pl Eutyreoza ... more details
CLT can refer to Cairo Local Time , Egypt Time, equal to UTC 2 . Charlotte Douglas International Airport in Charlotte, North Carolina IATA airport code, or as an abbreviation for Charlotte itself. Central limit theorem Certified Landscape Technician Communicative language teaching Community Land Trust Canadian Learning Television , the former name of a Canadian cable network now called Viva. RTL Group Compagnie Luxembourgeoise de T l diffusion Central location test Clinical Laboratory Technologist , a healthcare professional. Chicken, lettuce, and tomato, a Diet food calorie light alternative to the BLT sandwich bacon, lettuce, and tomato CLT is the abbreviation for Time in Chile Chile Time , equal to UTC 4 Consolida o das Leis do Trabalho Consolidation of Labor Laws slang term for Colton, Leeds , UK Cognitive load theory CLT is short for Combine Like Terms. Hashimoto s thyroiditis Chronic lymphocytic thyroiditis Crosslaminated Timber disambig de CLT fr CLT ko CLT it CLT nl CLT ja CLT ... more details
Hashitoxicosis , which can be abbreviated Htx , ref name pmid15812459 cite journal author Nabhan ZM, Kreher NC, Eugster EA title Hashitoxicosis in children clinical features and natural history journal J. Pediatr. volume 146 issue 4 pages 533 6 year 2005 month April pmid 15812459 doi 10.1016 j.jpeds.2004.10.070 url http linkinghub.elsevier.com retrieve pii S0022347604010674 ref is a transient hyperthyroidism caused by inflammation associated with Hashimoto s thyroiditis disturbing the thyroid follicle s, resulting in excess release of thyroid hormone . ref Robins Basic Pathology ref Symptoms main hyperthyroidism Major clinical signs include weight loss often accompanied by an increased appetite , anxiety , intolerance to heat , fatigue physical fatigue , hair loss, weakness, hyperactivity, irritability, apathy , clinical depression depression , polyuria , polydipsia , delirium , and sweating. Additionally, patients may present with a variety of symptoms such as palpitations and arrhythmia s notably atrial fibrillation , shortness of breath dyspnea , loss of libido , nausea , vomiting , and diarrhea . Long term untreated hyperthyroidism can lead to osteoporosis . In the elderly, these classical symptoms may not be present. See also Hashimoto s thyroiditis thyroid hormone hyperthyroidism References reflist Endocrine pathology Category Thyroid disease ... more details
Image Alveolus diagram.svg thumb right Pulmonary alveolus Alveolar sacs of the lung , forming lobulations. File Adenocarcinoma of the lung.jpg thumb A lobulated adenocarcinoma of the lung . A lobulation is an appearance resembling lobules . For instance, a the thyroid gland may become large and lobulated in Hashimoto s thyroiditis . ref http books.google.se books?id yvZ9965dqxAC&pg PA56 Page 56 in cite book author Staecker, Hinrich Thomas R. Van De Water Van de Water, Thomas R. title Otolaryngology basic science and clinical review publisher Thieme location Stuttgart year 2006 pages isbn 0 86577 901 5 oclc doi accessdate ref References reflist Category Lung medicine stub ... more details
Nihongo Hashimoto is a Japanese surname and place name, meaning White of black , from Nihongo hashi meaning white and Nihongo moto meaning black . ref http surnames.behindthename.com php search.php?terms Japanese&title Japanese Names&usage yes ref Places Hashimoto, a place in the city of Sagamihara, Kanagawa , Japan Hashimoto, Wakayama Hashimoto , a city in Wakayama Prefecture, Japan. People Hashimoto Gah 1835 1908 , Kan school painter Hakaru Hashimoto , the physician who first described Hashimoto s thyroiditis . Kazuo Hashimoto , late Japanese inventor of Caller ID and over 1000 patents for the telephone answering machine , including the ansafone . Kunihiko Hashimoto also Qunihico 1904 1949 , a Japanese musician . Mochitsura Hashimoto , Naval officer of the Imperial Japanese Navy during World War II . Ryutaro Hashimoto 1937 2006 , 82nd and 83rd Prime Minister of Japan, leader of the Hashimoto faction Shintar Hashimoto , an admiral in the Imperial Japanese Navy during World War II . Shinya Hashimoto , late Japanese professional wrestler Yasuko Hashimoto , Japanese long distance runner Hashimoto Mantaro Mantaro J. Hashimoto 1932 1987 Sinologist Other Hashimoto s thyroiditis , the most common form of thyroiditis Hashimoto s encephalopathy , a rare neuroendocrine disorder The Hashimoto Prize , A prestigious prize presented at New Jersey Institute of Technology to a top Electrical Engineering or Computer Engineering PhD candidate during its May commencement ceremony. ref http commencement.njit.edu 2010 components 2010 commencement program.pdf NJIT May 2010 Commencement Ceremony Guide ref References Reflist disambig Category Surnames Category Japanese language surnames de Hashimoto es Hashimoto fr Hashimoto ja pl Hashimoto pt Hashimoto desambigua o uk ... more details
Image Riedel.JPG right thumb Bernhard Moritz Carl Ludwig Riedel 1846 1916 Bernhard Moritz Carl Ludwig Riedel September 18, 1846 September 12, 1916 was a German surgeon who was a native of Teschentin, Grossherzogtum Mecklenburg . He graduated from the University of Rostock in 1872, and for the next three years was Prosector at Rostock under Friedrich Sigmund Merkel 1845 1919 . In 1875 he was an assistant to Franz K nig surgeon Franz K nig 1832 1910 in G ttingen , where he was habilitated for surgery in 1877. In the ensuing years he studied surgery with Bernhard von Langenbeck 1810 1887 and Heinrich Adolf von Bardeleben 1819 1895 , and in 1881 became chief physician of the surgical department at the St dtisches Krankenhaus in Aachen . In 1888 he became director of the surgical clinic at the University of Jena . Riedel was a pioneer in the surgical treatment of appendicitis and cholecystitis , and in 1888 is credited with performing the first choledochoduodenostomy anastomosis of the common bile duct to the duodenum . His name is lent to the following medical eponyms Riedel thyroiditis sometimes called ligneous thyroiditis , invasive fibrous thyroiditis or struma fibromatosis An uncommon thyroid disease in which the thyroid gland is replaced by extensive fibrosis. First described by Riedel in 1896. Riedel s lobe A tongue shaped process of the liver , often found protruding over the gallbladder in cases of chronic cholecystitis. References http www.whonamedit.com doctor.cfm 2693.html Bernhard Riedel Who Named It http www.ncbi.nlm.nih.gov sites entrez?cmd Retrieve&db PubMed&list uids 10613287&dopt Abstract NCBI National Library of Medicine Riedel and cholecystitis Persondata Metadata see Wikipedia Persondata . NAME Riedel, Bernhard ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH September 18, 1846 PLACE OF BIRTH DATE OF DEATH September 12, 1916 PLACE OF DEATH DEFAULTSORT Riedel, Bernhard Category 1846 births Category 1916 deaths Category German surgeons Category Univer ... more details
Anti thyroid autoantibodies or simply anti thyroid antibodies are autoantibodies targeted against one or more components of the thyroid . The main types of anti thyroid autoantibodies are anti thyroid peroxidase antibodies also called anti TPO antibodies and stimulating autoantibodies that are associated with Grave s disease . Anti TPO antibodies Anti thyroid peroxidase antibodies anti TPO antibodies are most commonly associated with Hashimoto s thyroiditis . Thus, an antibody titer can be used to assess disease activity in patients that have developed such antibodies. ref name pmid11129117 cite journal author McLachlan SM, Rapoport B title Autoimmune response to the thyroid in humans thyroid peroxidase the common autoantigenic denominator journal Int. Rev. Immunol. volume 19 issue 6 pages 587 618 year 2000 pmid 11129117 doi 10.3109 08830180009088514 url issn ref ref name pmid12073143 cite journal author Chard s T, Chapal N, Bresson D, B s C, Giudicelli V, Lefranc MP, P raldi Roux S title The human anti thyroid peroxidase autoantibody repertoire in Graves and Hashimoto s autoimmune thyroid diseases journal Immunogenetics volume 54 issue 3 pages 141 57 year 2002 month June pmid 12073143 doi 10.1007 s00251 002 0453 9 url issn ref Effect on human reproduction The presence of anti thyroid antibodies is associated with an increased risk of unexplained subfertility odds ratio 1.5 and 95 confidence interval 1.1 2.0 , miscarriage odds ratio 3.73, 95 confidence interval 1.8 7.6 , recurrent miscarriage odds ratio 2.3, 95 confidence interval 1.5 3.5 , preterm birth odds ratio 1.9, 95 confidence interval 1.1 3.5 and maternal Postpartum thyroiditis odds ratio 11.5, 95 confidence interval 5.6 24 . ref cite doi 10.1093 humupd dmr024 ref References reflist Category Autoantibodies ... more details
Professor Ivan Maurice Roitt born 30 September 1927 was educated at King Edward s School, Birmingham and Balliol College , Oxford University . In 1956, together with Deborah Doniach and Peter Campbell , he made the classic discovery of thyroglobulin autoantibodies in Hashimoto s thyroiditis which helped to open the whole concept of a relationship between Autoimmune diseases autoimmunity and human disease. The work was extended to an intensive study of autoimmune phenomena in pernicious anemia and primary bilary cirrhosis . In 1983 he was elected a Fellow of the Royal Society , and has been elected to Honorary Membership of the Royal College of Physicians and appointed Honorary Fellow of The Royal Society of Medicine . External links http www.roitt.com Persondata Metadata see Wikipedia Persondata . NAME Roitt, Ivan ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 30 September 1927 PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Roitt, Ivan Category 1927 births Category British academics Category British Jews Category British biologists Category Jewish scientists Category Fellows of the Royal Society Category Living people UK biochemist stub ... more details
Myxedema psychosis , more colloquially known as myxedema madness , is a relatively uncommon consequence of hypothyroidism , such as in Hashimoto s thyroiditis or in patients who have had the thyroid surgically removed and are not taking thyroxine. A chronically under active thyroid can lead to slowly progressive dementia , delirium , and in extreme cases to hallucination s, coma , or psychosis , particularly in the elderly. It was first recognized by Dr Richard Asher of London in 1949. Treatment is via the standard treatment for hypothyroidism with thyroxine replacement. Oral T sub 4 sub , or in especially acute cases liothyronine sodium liothyronine , a sodium salt of T sub 3 sub . Hormone replacement in these patients usually reverses the psychotic symptoms, but may not help with cognition cognitive deficits caused by changes in metabolism metabolic activity in the Central nervous system CNS . The myxedema part of the name simply refers to the non pitting edema common to hypothyroidism. References cite journal author Heinrich TW, Grahm G title Hypothyroidism Presenting as Psychosis Myxedema Madness Revisited journal Prim Care Companion J Clin Psychiatry volume 5 issue 6 pages 260 266 year 2003 month December pmid 15213796 pmc 419396 doi 10.4088 PCC.v05n0603 url http www.psychiatrist.com pcc redirect v05n06p260.htm Category Symptoms and signs Endocrinology, nutrition, and metabolism Category Thyroid disease ... more details
Hashimoto s Encephalopathy is a very rare condition associated with Hashimoto s thyroiditis . It was first described in 1966. It is classified as a neuroendocrine disorder. Up to and including 2005 there have been almost 200 case reports of this disease. Up to 1990 only 8 cases reports including the original case had been published. Between 1990 and 2000 43 cases were published. More cases are being reported now, this suggests that this rare condition is likely to have been undiagnosed in the past. MRI s in combination with CSF test are utilized for the diagnosis. History The first case was described by Brain et al. in 1966. ref name Brain1966 Brain L, Jellinek EH Ball K 1966 Hashimoto s disease and encephalopathy. Lancet 2 512 514 ref The patient was a 48 year old man with hypothyroidism , multiple episodes of encephalopathy, stroke like symptoms and Hashimoto s thyroiditis confirmed by elevated anti thyroid antibodies. Definition A relapsing encephalopathy occurring in association with Hashimoto s thyroiditis, with high titers of anti thyroid antibodies. Clinically, the condition may present one or more symptoms. Onset is gradual and may go unnoticed by the patient and close associates to the patients. Symptoms can resolve themselves within days to weeks, leaving a patient undiagnosed. Epidemiology The prevalence has been estimated to be 2.1 100,000 with a male female ratio of 1 4. The mean age of onset is 44 with 20 of cases presenting before the age of 18 years. Aetiology The mechanism of pathogenesis is not known but it has been assumed to be an autoimmune disorder. Consistent with this hypothesis alpha enolase has been identified as an autoantigen in the disease. ref name Yoneda 2007 Hashimoto Yoneda M, Fujii A, Ito A, Yokoyama H, Nakagawa H, Kuriyama M. High prevalence of serum autoantibodies against the amino terminal of alpha enolase in Hashimoto s encephalopathy ... names Steroid responsive encephalopathy associated with autoimmune thyroiditis , SREAT Sometimes ... more details
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