methyl br tetrahydrofuran 3 carbaldehyde image Streptomycin3.svg image2 Streptomycin 1ntb xtal 3D balls.png ... and intramuscular streptomycin in patients with tuberculosis journal Pharmacotherapy journal ... streptomycin author year 2006 title Taking Streptomycin during pregnancy and breastfeeding ... injection Intramuscular , Intravenous therapy intravenous legal US Rx only legal UK POM width 208 Streptomycin ... Streptomyces griseus . Streptomycin is a bactericidal antibiotic. ref name Singh1954 cite journal author Singh B, Mitchison DA date 16 January 1954 title Bactericidal activity of streptomycin ... 130 132 pmc 2084433 pmid 13106497 doi 10.1136 bmj.1.4854.130 ref Streptomycin cannot be given orally ... is ototoxicity , which can cause ear damage. Mechanism of action Streptomycin is a protein synthesis .... However at low concentrations Streptomycin only inhibits growth of the bacteria by inducing ... Biochemistry edition 3rd publisher John Wiley & Sons page 1341 year 2004 isbn 0 471 19250 X ref Streptomycin ... antibiotic. History Streptomycin was first isolated on October 19, 1943 by Albert Schatz scientist ... . ref cite journal author Comroe JH Jr title Pay dirt the story of streptomycin. Part I from ... , clavacin , streptothricin , streptomycin, grisein , neomycin , fradicin , candicidin and candidin . Of these, streptomycin and neomycin found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first antibiotic that could be used to cure the disease ... randomized trial of streptomycin against pulmonary tuberculosis was carried out in 1946 1947 by the MRC ... medicine , streptomycin is the first line antibiotic for use against gram negative bacteria ... injection. While streptomycin is traditionally given intramuscular injection intramuscular ... be administered intravenous injection intravenous ly. ref name Zhu2001 Pesticide Streptomycin is also used as a pesticide, to combat the growth of bacteria, fungi, and algae. Streptomycin controls ... more details
enzyme Name streptomycin 6 kinase EC number 2.7.1.72 CAS number 37278 11 8 IUBMB EC number 2 7 1 72 GO code 0050300 image width caption In enzymology , a streptomycin 6 kinase EC number 2.7.1.72 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math ADP streptomycin 6 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are adenosine diphosphate ADP and streptomycin 6 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP streptomycin 6 phosphotransferase . Other names in common use include streptidine kinase , SM 6 kinase , streptomycin 6 kinase phosphorylating , streptidine kinase phosphorylating , streptomycin 6 O phosphotransferase , and streptomycin 6 phosphotransferase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 cite journal author Walker JB, Walker MS date 1967 title Streptomycin biosynthesis. Enzymatic synthesis of O phosphorylstreptidine from streptidine and adenosinetriphosphate journal Biochim. Biophys. Acta. volume 148 pages 335&ndash 41 pmid 6075410 issue 2 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
enzyme Name streptomycin 3 adenylyltransferase EC number 2.7.7.47 CAS number 52660 23 8 IUBMB EC number 2 7 7 47 GO code 0009012 image width caption In enzymology , a streptomycin 3 adenylyltransferase EC number 2.7.7.47 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math diphosphate 3 adenylylstreptomycin Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are diphosphate and 3 adenylylstreptomycin . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing nucleotide groups nucleotidyltransferase s . The systematic name of this enzyme class is ATP streptomycin 3 adenylyltransferase . Other names in common use include streptomycin adenylate synthetase , streptomycin adenyltransferase , streptomycin adenylylase , streptomycin adenylyltransferase , streptomycin spectinomycin adenylyltransferase , AAD 3 , and aminoglycoside 3 adenylyltransferase . References reflist 1 cite journal author Harwood JH, Smith DH date 1969 title Resistance factor mediated streptomycin resistance journal J. Bacteriol. volume 97 pages 1262&ndash 71 pmid 4887506 issue 3 pmc 249843 enzyme stub Category EC 2.7.7 Category Enzymes of unknown structure ... more details
enzyme Name streptomycin 3 kinase EC number 2.7.1.87 CAS number 39391 15 6 IUBMB EC number 2 7 1 87 GO code 0050299 image width caption In enzymology , a streptomycin 3 kinase EC number 2.7.1.87 is an enzyme that catalysis catalyzes the chemical reaction ATP streptomycin math rightleftharpoons math ADP streptomycin 3 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and streptomycin , whereas its two product chemistry products are adenosine diphosphate ADP and streptomycin 3 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP streptomycin 3 phosphotransferase . Other names in common use include streptomycin 3 kinase phosphorylating , and streptomycin 3 phosphotransferase . References reflist 1 cite journal author Walker JB, Skorvaga M year 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 Category EC 2.7.1 Category Enzymes of unknown structure enzyme stub ... more details
enzyme Name streptomycin 6 phosphatase EC number 3.1.3.39 CAS number 9055 33 8 IUBMB EC number 3 1 3 39 GO code 0050301 image width caption In enzymology , a streptomycin 6 phosphatase EC number 3.1.3.39 is an enzyme that catalysis catalyzes the chemical reaction streptomycin 6 phosphate H sub 2 sub O math rightleftharpoons math streptomycin phosphate Thus, the two substrate biochemistry substrates of this enzyme are streptomycin 6 phosphate and water H sub 2 sub O , whereas its two product chemistry products are streptomycin and phosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on phosphoric ester monoester bonds. The systematic name of this enzyme class is streptomycin 6 phosphate phosphohydrolase . Other names in common use include streptomycin 6 phosphate phosphatase , streptomycin 6 phosphate phosphohydrolase , and streptomycin 6 P phosphohydrolase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Streptomycin biosynthesis and metabolism. Phosphate transfer from dihydrostreptomycin 6 phosphate to inosamines, streptamine, and 2 deoxystreptamine journal J. Biol. Chem. volume 248 pages 2441&ndash 6 pmid 4121457 issue 7 cite journal author Walker MS, Walker JB date 1971 title Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy scyllo inositol phosphate and streptomycin streptidino phosphate journal J. Biol. Chem. volume 246 pages 7034&ndash 40 pmid 4331203 issue 22 hydrolase stub Category EC 3.1.3 Category Enzymes of unknown structure ... more details
Image Streptomycin structure.png thumb 120px right Streptomycin , an important antibiotic drug produced by Streptomyces bacteria Secondary metabolism also called special metabolism is a term for pathways and small molecule products of metabolism that are not absolutely required for the survival of the organism . Examples of the products include antibiotics and pigment s. To distinguish non secondary ordinary metabolism, the term basic metabolism is sometimes used. Secondary metabolite s are produced by microbe s, plants, fungi and animals, but not by all of them. Important secondary metabolites main Secondary metabolite Antibiotic s, such as streptomycin and penicillin Pigment s, such as delphinidin References Unreferenced date June 2008 External links http www.biologie.uni hamburg.de b online e20 20.htm Secondary metabolism in plants Category Metabolism biochemistry stub fi Sekundaarimetabolia es Metabolito secundario ... more details
Unreferenced type bacteria auto yes date December 2009 Taxobox image Streptomyces sp 01.png image width 240px image caption Slide culture of a Streptomyces species regnum Bacteria phylum Actinobacteria classis Actinobacteria ordo Actinomycetales subordo Streptomycineae subordo authority Rainey et al. 1997 familia Streptomycetaceae familia authority Waksman & Henrici 1943 subdivision ranks Genera Verify source date July 2010 only these two? Streptoverticillium here included in Streptomyces subdivision Kitasatospora br Streptomyces br Streptomycetaceae is a family biology family of Actinobacteria , making up to the monotypic suborder Streptomycineae . It includes the important genus Streptomyces . This was the original source of many antibiotics , namely streptomycin . Streptomycin was the first antibiotic against tuberculosis . Category Actinomycetales Bacteria stub es Streptomycetaceae nl Streptomycetaceae ... more details
Image Waksman sign.jpg thumb right 300px Sign at the side entrance of the Waksman Institute The Waksman Institute of Microbiology is a research facility on the Busch Campus Rutgers University Busch Campus of Rutgers University . It is named after Selman Waksman , who was a faculty member who won the Nobel Prize for Medicine in 1952 for research which led to the discovery of streptomycin . 18 antibiotics were isolated in Waksman s laboratory. Streptomycin and neomycin , and actinomycin , were commercialized. The current director of the Institute is Professor Joachim Messing . References New York Times Thursday, May 23, 1974 Waksman Institute Marks Two Decades of Research Royalties Running Out. A group of scientists who hope to help solve some of the world s biggest problems through control of its smallest living organisms celebrated the 20th anniversary of their combined effort this week. Rutgers Category Rutgers University ... more details
Albert Schatz may refer to Albert Schatz law 1879 ? , law professor and historian Albert Gerard Schatz 1921 1985 , U.S. federal judge Albert Schatz music 1839 1910 , musicologist, composer, and librettist Albert Schatz scientist 1922 2005 , microbiologist, co discoverer of streptomycin hndis name Schatz, Albert bg fr Albert Schatz ... more details
Albert Schatz 2 February 1922 &ndash 17 January 2005 was the co discoverer of streptomycin , the first ... of streptomycin was credited only to Schatz s supervisor, Selman Waksman . ref name young Early ... from Rutgers. Streptomycin Discovery and War over Nobel Prize With a meager stipend, Schatz lived ... University. Dr Waksman was at the last stages of purifying streptomycin, testing it at an external ... issued his doctorate thesis on the discovery of streptomycin. Career Originally, the discovery of streptomycin was credited only to Schatz s supervisor, Selman Waksman , who would later receive ... brought litigation against Waksman, requesting recognition as streptomycin s co discoverer and a portion of streptomycin royalties. Schatz s requests were eventually granted in an out of court settlement ... on developing streptomycin. Schatz was a socialist, an active environmentalist and was involved in local ... schatz 485352.html Albert Schatz Co discoverer of streptomycin . The Independent. ref which was criticized ... books.htm Finding 20Dr. 20Schatz Finding Dr. Schatz The Discovery of Streptomycin and a Life It Saved with Schatz. The book chronicled his discovery of streptomycin and meeting Auerbacher ... of streptomycin, dies at 84 1504 Rutgers Focus obituary http muse.jhu.edu journals journal of the history of medicine and allied sciences v059 59.3kingston.html Streptomycin, Schatz v. Waksman ... containing scanned newspaper clippings from the time of the discovery of Streptomycin References ... more details
Unreferenced date June 2008 The term broad spectrum antibiotic refers to an antibiotic with activity against a wide range of disease causing bacteria . It also means that it acts against both Gram positive and Gram negative bacteria. This is in contrast to a narrow spectrum antibiotic which is effective against only specific families of bacteria . A good example of a commonly used broad spectrum antibiotic is levofloxacin . Fact date June 2008 Uses Broad spectrum antibiotics are properly used in the following medicine medical situations Empirically prior to identifying the causative bacteria when there is a wide differential and potentially serious illness would result in delay of treatment. This occurs, for example, in meningitis , where the patient can become so ill that he she could die within hours if broad spectrum antibiotics are not initiated. For drug resistant bacteria that do not respond to other, more narrow spectrum antibiotic s. In super infections where there are multiple types of bacteria causing illness, thus warranting either a broad spectrum antibiotic or combination antibiotic therapy. Examples In medicine amoxicillin levofloxacin , gatifloxacin , moxifloxacin In veterinary medicine , Co amoxiclav , in small animals penicillin & streptomycin and oxytetracycline in farm animals penicillin and sulfonamide medicine potentiated sulfonamides in horses . Others streptomycin tetracycline chloramphenicol Slightly Broad ampicillin See also Empiric therapy Category Antibiotics Category Microbiology ... more details
enzyme Name guanidinodeoxy scyllo inositol 4 phosphatase EC number 3.1.3.40 CAS number 9055 28 1 IUBMB EC number 3 1 3 40 GO code 0047383 image width caption In enzymology , a guanidinodeoxy scyllo inositol 4 phosphatase EC number 3.1.3.40 is an enzyme that catalysis catalyzes the chemical reaction 1 guanidino 1 deoxy scyllo inositol 4 phosphate H sub 2 sub O math rightleftharpoons math 1 guanidino 1 deoxy scyllo inositol phosphate Thus, the two substrate biochemistry substrates of this enzyme are 1 guanidino 1 deoxy scyllo inositol 4 phosphate and water H sub 2 sub O , whereas its two product chemistry products are 1 guanidino 1 deoxy scyllo inositol and phosphate . This enzyme belongs to the family of hydrolase s, specifically those acting on phosphoric ester monoester bonds. The systematic name of this enzyme class is 1 guanidino 1 deoxy scyllo inositol 4 phosphate 4 phosphohydrolase . Other names in common use include 1 guanidino scyllo inositol 4 phosphatase , and 1 guanidino 1 deoxy scyllo inositol 4 P phosphohydrolase . References reflist 1 cite journal author Walker MS, Walker JB date 1971 title Streptomycin biosynthesis. Separation and substrate specificities of phosphatases acting on guanidinodeoxy scyllo inositol phosphate and streptomycin streptidino phosphate journal J. Biol. Chem. volume 246 pages 7034&ndash 40 pmid 4331203 issue 22 Category EC 3.1.3 Category Enzymes of unknown structure hydrolase stub ... more details
Drugbox type combo component1 Streptomycin class1 Aminoglycoside antibiotic component2 Dihydrostreptomycin class2 Aminoglycoside antibiotic CAS number ATC prefix J01 ATC suffix GA02 PubChem 202223 DrugBank pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Streptoduocin is an aminoglycoside antibiotic . It is a mixture of streptomycin and dihydrostreptomycin . ref name pmid13261867 cite journal author SHUBIN H, HEIKEN CA, GLASKIN A, PENNES E, CHAKRAVARTY S, RUTBERG F title A study of the neurotoxicity of streptoduocin on tuberculous patients journal Dis Chest volume 28 issue 4 pages 447 50 year 1955 pmid 13261867 doi url http www.chestjournal.org cgi content abstract 28 4 447 ref References reflist AminoglycosideAntiBiotics Category Aminoglycoside antibiotics Category Combination antibiotics antibiotic stub ... more details
in soil &mdash and their decomposition promoted the discovery of Streptomycin , and several other ... of streptomycin the first antibiotic active against tuberculosis. In 2005 Selman Waksman was designated ... streptomycin, which was the first effective treatment for tuberculosis. ref cite web title Selman Waksman ... actinomycin , clavacin , streptothricin , streptomycin , grisein , neomycin , fradicin , candicidin , candidin , and others. Two of these, streptomycin and neomycin , have found extensive application in the treatment of numerous infectious diseases. Streptomycin was the first antibiotic that could ... created it. ref Streptomycin main streptomycin Waksman had been studying the Streptomyces family ... griseus . Streptomycin was isolated from S. griseus and found effective against tuberculosis by one ... and credit for the discovery of streptomycin and its usefulness as an antibiotic were strongly contested ... to legal and scientific credit as co discoverer of streptomycin. ref name young cite news first ... weekend story 0,3605,823114,00.html quote The story of streptomycin of scientific triumphs, all ... in 1952 for for his discovery of streptomycin, the first antibiotic effective against tuberculosis though it is understood that the Nobel Prize was awarded not only for the discovery of streptomycin ... journals journal of the history of medicine and allied sciences v059 59.3kingston.html Streptomycin ..., microbiologist who discovered Streptomycin and many antibiotics. DATE OF BIRTH 22 July 1888 ... more details
enzyme Name scyllo inosamine 4 phosphate amidinotransferase EC number 2.1.4.2 CAS number 52227 63 1 IUBMB EC number 2 1 4 2 GO code 0015069 image width caption Orphan date February 2009 In enzymology , a scyllo inosamine 4 phosphate amidinotransferase EC number 2.1.4.2 is an enzyme that catalysis catalyzes the chemical reaction L arginine 1 amino 1 deoxy scyllo inositol 4 phosphate math rightleftharpoons math L ornithine 1 guanidino 1 deoxy scyllo inositol 4 phosphate Thus, the two substrate biochemistry substrates of this enzyme are L arginine and 1 amino 1 deoxy scyllo inositol 4 phosphate , whereas its two product chemistry products are L ornithine and 1 guanidino 1 deoxy scyllo inositol 4 phosphate . This enzyme belongs to the family of transferase s that transfer one carbon groups, specifically the amidinotransferases. The systematic name of this enzyme class is L arginine 1 amino 1 deoxy scyllo inositol 4 phosphate amidinotransferase . Other names in common use include L arginine inosamine P amidinotransferase , inosamine P amidinotransferase , L arginine inosamine phosphate amidinotransferase , and inosamine phosphate amidinotransferase . This enzyme participates in streptomycin biosynthesis . Structural studies As of late 2007, only one tertiary structure structure has been solved for this class of enzymes, with the Protein Data Bank PDB accession code PDB link 1BWD . References reflist 1 cite journal author Walker MS and Walker JB date 1966 title Enzymic studies on the biosynthesis of streptomycin, transamidation of inosamine and streptamine derivatives journal J. Biol. Chem. volume 241 pages 1262&ndash 1269 transferase stub Category EC 2.1.4 Category Enzymes of known structure it Scillo inosammina 4 fosfato amidinotransferasi ... more details
enzyme Name 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol transaminase EC number 2.6.1.56 CAS number 57127 19 2 IUBMB EC number 2 6 1 56 GO code 0047311 image width caption In enzymology , a 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol transaminase EC number 2.6.1.56 is an enzyme that catalysis catalyzes the chemical reaction 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol pyruvate math rightleftharpoons math 1D 1 guanidino 1 deoxy 3 dehydro scyllo inositol L alanine Thus, the two substrate biochemistry substrates of this enzyme are 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol and pyruvate , whereas its two product chemistry products are 1D 1 guanidino 1 deoxy 3 dehydro scyllo inositol and L alanine . This enzyme belongs to the family of transferase s, specifically the transaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is 1D 1 guanidino 3 amino 1,3 dideoxy scyllo inositol pyruvate aminotransferase . Other names in common use include guanidinoaminodideoxy scyllo inositol pyruvate aminotransferase , and L alanine N amidino 3 or 5 keto scyllo inosamine transaminase . References reflist 1 cite journal author Walker JB date 1971 title Enzymatic reactions involved in streptomycin biosynthesis and metabolism journal Lloydia. volume 34 pages 363&ndash 71 pmid 4376579 issue 4 cite journal author Walker JB, Walker MS date 1969 title Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines journal Biochemistry. volume 8 pages 763&ndash 70 pmid 5781017 doi 10.1021 bi00831a003 issue 3 transferase stub Category EC 2.6.1 Category Enzymes of unknown structure ... more details
enzyme Name scyllo inosamine 4 kinase EC number 2.7.1.65 CAS number 37278 08 3 IUBMB EC number 2 7 1 65 GO code 0050276 image width caption In enzymology , a scyllo inosamine 4 kinase EC number 2.7.1.65 is an enzyme that catalysis catalyzes the chemical reaction ATP 1 amino 1 deoxy scyllo inositol math rightleftharpoons math ADP 1 amino 1 deoxy scyllo inositol 4 phosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and 1 amino 1 deoxy scyllo inositol , whereas its two product chemistry products are adenosine diphosphate ADP and 1 amino 1 deoxy scyllo inositol 4 phosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP 1 amino 1 deoxy scyllo inositol 4 phosphotransferase . Other names in common use include scyllo inosamine kinase phosphorylating , scyllo inosamine kinase , and ATP inosamine phosphotransferase . This enzyme participates in streptomycin biosynthesis . References reflist 1 cite journal author Walker JB date 1971 title Enzymatic reactions involved in streptomycin biosynthesis and metabolism journal Lloydia. volume 34 pages 363&ndash 71 pmid 4376579 issue 4 cite journal author Walker JB, Walker MS date 1967 title Enzymatic synthesis of streptidine from scyllo inosamine journal Biochemistry. volume 6 pages 3821&ndash 9 pmid 6076630 doi 10.1021 bi00864a028 issue 12 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
Philip Montagu D Arcy Hart , CBE , June 25, 1900 July 30, 2006 was a British medical researcher and pioneer in tuberculosis treatment. Grandson of Samuel Montagu, 1st Baron Swaythling , he became a consultant physician at University College Hospital at the age of 34. Three years later, he joined the Medical Research Council and became involved with much of the MRC s early research into dust diseases in coal miners. He was a member of the Medical Research Council Streptomycin in Tuberculosis Trials Committee their study evaluating the use of streptomycin in treating tuberculosis is generally accepted as the first randomized clinical trial. At the age of 71 Hart published a seminal paper in the Journal of Experimental Medicine , showing that the intracellular pathogen Mycobacterium tuberculosis avoids destruction in the cell s lysosomes by circumventing these organelles altogether a trick now known to be used by many other intracellular pathogens. In 1941, Hart married Ruth Meyer, later a medical gynaecologist. They had a son, Oliver Hart economist Oliver Hart . Philip D Arcy Hart died at the age of 106 in 2006. ref cite web url http www.genarians.com In 20Memoriam 202006.html title Noted Nonagenarians & Centenarians In Memoriam 2006 publisher generians.com ref References Reflist Persondata Metadata see Wikipedia Persondata . NAME Darcy Hart, Philip ALTERNATIVE NAMES SHORT DESCRIPTION PLACE OF BIRTH PLACE OF DEATH date of birth 1900 date of death 2006 DATE OF BIRTH June 25, 1900 DATE OF DEATH July 30, 2006 DEFAULTSORT Hart, Philip Darcy Category Epidemiologists Category English medical doctors Category English centenarians Category English Jews Category Old Cliftonians Category Tuberculosis Category 1900 births Category 2006 deaths UK med bio stub ... more details
STR , StR , Str or str may stand for Short tandem repeat , in DNA testing Special Theory of Relativity , Einstein s theory S. T. Rajendar , a South Indian actor. String computer science , in computing Steps To Reproduce , in computing, used in bug filing and testing R Tree Sort Tile Recursive an efficient and particularly effective method of bulk loading an R Tree United States Trade Representative , formerly known as a Special Trade Representative Stuttgart Airport , Germany Scuderia Toro Rosso , a Formula 1 racing team Suspicious Transaction Report, see Currency Transaction Report S minaire Saint Joseph de Trois Rivi res , a school in Quebec Specialized Technology Resources , an American corporation Suspend to RAM , in computing Sociedade da Terra Redonda , a Brazilian atheist and skeptic organization Super Trucks Racing , a video game for the PlayStation 2 An accepted abbreviation for Streptomycin , an antibiotic, in bacterial molecular biology Specialty Registrar StR , a medical specialty title in the UK intended to replace SpR disambig cs STR de STR eo STR fr STR ko STR id STR it STR ja STR pl STR pt STR ... more details
italic title Taxobox name Mycobacterium kubicae regnum Bacteria phylum Actinobacteria ordo Actinomycetales subordo Corynebacterineae familia Mycobacterium Mycobacteriaceae genus Mycobacterium species M. kubicae binomial Mycobacterium kubicae binomial authority Floyd et al. 2000, ATCC 700732 Mycobacterium kubicae Description Gram positive , nonmotile and acid fast rods. Cells are typically rod shaped, with some coccoid forms. Colony characteristics Smooth and domed, with a yellow scotochromogenic pigment on Middlebrook 7H11 agar, film like on L wenstein Jensen media. Physiology Mature growth in 21 days between 33 C and 37 C. Isolates are resistant to amikacin and rifampin Partially resistant to ciprofloxacin , cycloserine , ethambutol , isoniazid , rifabutin and streptomycin , Susceptible to clarithromycin , clofazimine and ethionamide . Pathogenicity. Distribution. Pathogenesis Not known to be associated with disease. Biosafety level unknown Type strain The type strain was isolated from human sputum . Strain ATCC 700732 CDC 941078 CIP 106428 DSM 44627 JCM 13573. References reflist Floyd et al. 2000. Mycobacterium kubicae sp. nov., a slowly growing, scotochromogenic Mycobacterium. Int. J. Syst. Evol. Microbiol., 50, 1811 1816. Mycobacteria DEFAULTSORT Mycobacterium Kubicae Category Acid fast bacilli Category Corynebacterineae Category Nontuberculous mycobacteria Mycobacterium stub ... more details
enzyme Name glutamine scyllo inositol transaminase EC number 2.6.1.50 CAS number 9033 03 8 IUBMB EC number 2 6 1 50 GO code 0047310 image width caption In enzymology , a glutamine scyllo inositol transaminase EC number 2.6.1.50 is an enzyme that catalysis catalyzes the chemical reaction L glutamine 2,4,6 3,5 pentahydroxycyclohexanone math rightleftharpoons math 2 oxoglutaramate 1 amino 1 deoxy scyllo inositol Thus, the two substrate biochemistry substrates of this enzyme are L glutamine and 2,4,6 3,5 pentahydroxycyclohexanone , whereas its two product chemistry products are 2 oxoglutaramate and 1 amino 1 deoxy scyllo inositol . This enzyme belongs to the family of transferase s, specifically the transaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is L glutamine 2,4,6 3,5 pentahydroxycyclohexanone aminotransferase . Other names in common use include glutamine scyllo inosose aminotransferase , L glutamine keto scyllo inositol aminotransferase , glutamine scyllo inosose transaminase , and L glutamine scyllo inosose transaminase . It employs one cofactor biochemistry cofactor , pyridoxal phosphate . References reflist 1 cite journal author Walker JB, Walker MS date 1969 title Streptomycin biosynthesis. Transamination reactions involving inosamines and inosadiamines journal Biochemistry. volume 8 pages 763&ndash 70 pmid 5781017 doi 10.1021 bi00831a003 issue 3 transferase stub Category EC 2.6.1 Category Pyridoxal phosphate enzymes Category Enzymes of unknown structure ... more details
enzyme Name dihydrostreptomycin 6 phosphate 3 alpha kinase EC number 2.7.1.88 CAS number 39391 14 5 IUBMB EC number 2 7 1 88 GO code 0047333 image width caption In enzymology , a dihydrostreptomycin 6 phosphate 3 alpha kinase EC number 2.7.1.88 is an enzyme that catalysis catalyzes the chemical reaction ATP dihydrostreptomycin 6 phosphate math rightleftharpoons math ADP dihydrostreptomycin 3 alpha,6 bisphosphate Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and dihydrostreptomycin 6 phosphate , whereas its two product chemistry products are adenosine diphosphate ADP and dihydrostreptomycin 3 alpha,6 bisphosphate . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with an alcohol group as acceptor. The systematic name of this enzyme class is ATP dihydrostreptomycin 6 phosphate 3 alpha phosphotransferase . Other names in common use include dihydrostreptomycin 6 phosphate kinase phosphorylating , and ATP dihydrostreptomycin 6 P 3 alpha phosphotransferase . References reflist 1 cite journal author Walker JB, Skorvaga M date 1973 title Phosphorylation of streptomycin and dihydrostreptomycin by Streptomyces. Enzymatic synthesis of different diphosphorylated derivatives journal J. Biol. Chem. volume 248 pages 2435&ndash 40 pmid 4121456 issue 7 enzyme stub Category EC 2.7.1 Category Enzymes of unknown structure ... more details
Robert Kilpatrick, Lord Kilpatrick of Kincraig July 29, 1926 is a British politician. Life He is a member of the House of Lords since 1996. There he sits as a crossbencher. Having suffered from tuberculosis when younger and been one of the first patients to be treated with the antibiotic streptomycin , Lord Kilpatrick is now a patron of the charity TB Alert . ref http www.tbalert.org about people.php TB Alert website ref References http biographies.parliament.uk parliament default.asp?id 27003 Parliament.uk references Sources http hansard.millbanksystems.com people mr robert kilpatrick http www.eurosource.eu.com engine.asp?lev1 4&lev2 38&menu 73&biog y&id 27003&group 5&Page Lord 20Kilpatrick 20of 20Kincraig 20 20Political 20Biography http www.burkes peerage.net familyhomepage.aspx?FID 0&FN KILPATRICKOFKINCRAIG Persondata Metadata see Wikipedia Persondata . NAME Kilpatrick ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH July 29, 1926 PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH DEFAULTSORT Kilpatrick Category Cross bench life peers Category Living people Category 1926 births ... more details
Research Council Streptomycin in Tuberculosis Trials Committee and their study evaluating the use of streptomycin in treating tuberculosis, is generally accepted as the first randomised clinical ... 1937 London The Lancet , 1937. Medical Research Council 1948 Streptomycin in Tuberculosis Trials Committee. Streptomycin treatment of pulmonary tuberculosis. British Medical Journal , 2 769 83 ... in the Medical Research Council s clinical trial of streptomycin in pulmonary tuberculosis ... more details
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