For coughing resulting from viral infections Cough Infobox disease Name Pertussis Image Pertussis.jpg Caption A young boy coughing due to pertussis. DiseasesDB 1523 ICD10 ICD10 A 37 a 30 ICD9 ICD9 033 ... MeshID D014917 Pertussis , also known as whooping cough pron en hu p k f or w p k f , is a highly contagious bacterial disease caused by Bordetella pertussis . Symptoms are initially mild, and then develop ... of Bordetella pertussis infection and disease journal Curr Opin Pharmacol volume 7 ... of pertussis are a paroxysmal cough, inspiratory whoop, and vomiting after coughing. ref name ... adolescent or adult patient have pertussis? journal JAMA volume 304 issue 8 pages 890 6 year 2010 month August pmid 20736473 doi 10.1001 jama.2010.1181 ref The cough from pertussis has been ... is pertussis is nearly doubled. On the other hand, the absence of a paroxysmal cough or posttussive ... whether antibody against pertussis toxin or another component of B. pertussis is present at high ... pertussis, are increasingly being encouraged to be vaccinated. Vaccine Pertussis vaccines are highly ... from pertussis. ref name JAMA2010 ref cite journal author Versteegh FGA, Schellekens JFP, Fleer A, Roord JJ. title Pertussis a concise historical review including diagnosis, incidence, clinical manifestations .... The pertussis component of the DPT vaccine accounted for most of the minor local and systemic side ... some vaccines, immunization against pertussis does not confer life long immunity. While adolescents and adults rarely die if they contract pertussis after the effects of their childhood vaccinations ... of discontinuing pertussis vaccination after the age of seven. Even where they are available, most adults have not received booster shots and lack immunity to the disease. Infection with pertussis ... whole cell pertussis vaccine. An acellular vaccine preparation for adults and adolescents ... Pertussis Vaccine Adsorbed, ADACEL, Aventis Pasteur Ltd url http www.fda.gov Cber products tdapave061005.htm ... more details
italic title Taxobox color lightgrey name Bordetella pertussis image Bordetella pertussis.jpg image width ... familia Alcaligenaceae genus Bordetella species B. pertussis binomial Bordetella pertussis binomial authority Bergey et al. 1923 br Moreno L pez 1952 Bordetella pertussis is a Gram negative , Aerobic organism aerobic coccobacillus of the genus Bordetella , and the causative agent of pertussis or whooping cough. Unlike Bordetella bronchiseptica B. bronchiseptica , B. pertussis is non motile . There does not appear to be a zoonotic reservoir for B. pertussis &mdash humans are its only ... is 7 14 days. PertussisPertussis or whooping cough is an infection of the respiratory system and characterized ... than 100 children died from pertussis. Worldwide in 2000, according to the WHO, around 39 million ... of introducing vaccination in England. ref name urlHPA Whooping Cough Pertussis cite web url http ... title HPA Whooping Cough Pertussis format work accessdate 2009 04 12 ref Bordetella pertussis infects its host by colonizing lung epithelial cells. The bacterium contains a surface protein ... hosts. Bordetella pertussis has the ability to inhibit the function of the host s immune system. Two toxins, known as the pertussis toxin or PTx and adenylate cyclase CyaA , are responsible for this inhibition ... coughs, sneezes, or laughs. Pertussis vaccine is part of the DTaP diphtheria , tetanus , acellular pertussis immunization . The paroxysmal cough precedes a crowing inspiratory sound characteristic of pertussis .... This is because Bordetella pertussis inhibits the immune response and therefore very little mucus ... undiagnosed in adults for many months. Bordetella pertussis also produces a lymphocytosis promoting ... pertussis.html title Bordetella pertussis and Whooping Cough author Kenneth Todar ... links http www.who.int immunization topics pertussis en index1.html Pertussis Information from the World ... Bordetella pertussis in ARUP Consult The Physician s Guide to Laboratory Test Selection and Interpretation ... more details
Drugbox type vaccine image target Bordetella pertussis vaccine type varies CAS number ATC prefix J07 ATC suffix AJ01 ATC supplemental ATC J07 AJ02 PubChem DrugBank pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Pertussis vaccine is a vaccine used against Bordetella pertussis . ref name urlMedlinePlus Medical Encyclopedia Pertussis vaccine cite web url http www.nlm.nih.gov medlineplus ency article 001561.htm title MedlinePlus Medical Encyclopedia Pertussis work accessdate 2010 07 02 ref It is a component of the DPT vaccine . Older versions of the vaccine involved inactivated cells. Newer versions are acellular, and are less likely to provoke a febrile state. ref cite journal author Patel SS, Wagstaff AJ title Acellular pertussis vaccine Infanrix DTPa SB 3 . A review of its immunogenicity, protective efficacy and tolerability in the prevention of Bordetella pertussis infection journal Drugs volume 52 month Aug pages 254 275 year 1996 pmid 8841742 issue 2 ref References Reflist Vaccines vaccine stub Category Vaccines ... more details
Pfam box Symbol Pertussis S1 Name Pertussis toxin, subunit 1 ref name pmid8075982 cite journal author Stein PE, Boodhoo A, Armstrong GD, Cockle SA, Klein MH, Read RJ title The crystal structure of pertussis ... family OPM protein Pfam box Symbol Pertussis S2S3 Name Pertussis toxin, subunit 2 and 3 image width ... Symbol Pertus S4 tox Name Pertussis toxin, subunit 4 image width caption Pfam PF09275 InterPro IPR015355 SMART Prosite SCOP 1prt TCDB OPM family OPM protein Pfam box Symbol Pertus S5 tox Name Pertussis ... OPM family OPM protein Pertussis toxin PT is a protein based AB5 toxin AB sub 5 sub type exotoxin produced by the bacterium Bordetella pertussis , ref name Sherris cite book author Ryan KJ Ray CG editors ... ZE title Pertussis toxin plays an early role in respiratory tract colonization by Bordetella pertussis journal Infect. Immun. volume 71 issue 11 pages 6358 66 year 2003 month November pmid 14573656 ..., Jackson E title Pertussis toxin sensitive G proteins and regulation of blood pressure in the spontaneously ... journal author Alfano M, Pushkarsky T, Poli G, Bukrinsky M title The B oligomer of pertussis toxin ... T, Lewis G title Pertussis toxin and the adenylate cyclase toxin from Bordetella pertussis activate ... ref name PUB00007589 cite journal author Locht C, Keith JM title Pertussis toxin gene nucleotide sequence ..., Casagli MC, Borri MG, Antoni G, Almoni M, Neri P, Ratti G title Cloning and sequencing of the pertussis ... role in the pathogenesis of pertussis . However, this was only discovered in the early 80s of the last century. The appearance of pertussis is quite recent, compared with other epidemic infectious diseases. The earliest mention of pertussis, or whooping cough , is of an outbreak in Paris in 1414. This was published in Moulton s The Mirror of Health, in 1640. Another epidemic of pertussis took place in Paris in 1578 and was described by a contemporary observer, Guillaume de Baillou. Pertussis ... cough. They were also the first to cultivate the Bordetella pertussis at the Pasteur Institute ... more details
Unreferenced date August 2009 Pertactin PRN is a highly immunogenic Virulence virulence factor of Bordetella pertussis , a bacterium that causes pertussis . Specifically, it is an outer membrane protein that promotes Cell adhesion adhesion to Vertebrate trachea trachea l epithelial cell s. PRN is purified from Bordetella pertussis and is used for the vaccine production as one of the important components of acellular pertussis vaccine. Citation needed date August 2009 Category Microbiology biochem stub de Pertactin es Pertactina ... more details
File Babyimmunization.jpg thumb 150px This Bangladesh i infant was being immunized, but cocooning would also involve vaccinating the mother and other close family members File HumanNewborn.JPG thumb 250px An infant has very little Immunity medical immunity to virus es Cocooning , also known as the Cocoon Strategy , ref name texas childrens cite web url http www.texaschildrens.org carecenters vaccine programs.aspx title The Cocoon Strategy Preventing Severe and Fatal Pertussis Whooping Cough in Infants Through Family Immunization publisher Texas Children s Hospital date accessdate ref is a vaccination strategy that has been recommended by the Centers for Disease Control and Prevention CDC in the United States since 2006. It aims to protect newborn infants from becoming infected with pertussis by administering DTaP tetanus, diphtheria and acellular pertussis booster vaccine to mothers, family members and any individuals who would come into regular contact with the newborn infant. By vaccinating these individuals with a pertussis booster a pool of persons is established around the newborn who are themselves protected from getting pertussis and passing it on to the young infant, thereby creating a cocoon of protection around the newborn. Young infants have the highest rate of pertussis in 87 100 of all deaths caused by pertussis, the victim is an infant of less than 6 months of age. ref name texas childrens Definition blockquote The concept of cocooning is simple. A Infant newborn baby has little if any Immunity medical immunity to influenza for the first 12 months of life. To ensure protection for the baby, immediate household contacts representing its cocoon are vaccinated against influenza so they won t transmit the virus to the baby. The program began in July 2006 with pertussis vaccination and it now includes seasonal Influenza vaccine influenza vaccinations as well. ref name cdc bulletin cite web url http www.cdc.gov flu professionals bulletin 2006 07 bulletin5 11 ... more details
Octave Gengou 1875 &ndash 1957 was a Belgian bacteriologist . He researched with Jules Bordet the Bordetella Bordetella pertussis bacteria. Biography Gengou worked at the Belgium Pasteur Institute in Brussels . With Jules Bordet in 1906 he isolated Bordetella pertussis in pure culture and declared is as the cause of Pertussis whooping cough . 1912 he developed the first Pertussis whooping cough vaccine . He also worked on various important fundamental research on a now common test for diseases e.G. the Wassermann Test of August von Wassermann See also Immunology Bacteriologist External links http www.bookrags.com biography octave gengou scit 061234 Biography of Octave Gengou Persondata Metadata see Wikipedia Persondata . NAME Gengou, Octave ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1875 PLACE OF BIRTH DATE OF DEATH 1957 PLACE OF DEATH DEFAULTSORT Gengou, Octave Category French microbiologists Category French biologists Category 1875 births Category 1957 deaths de Octave Gengou ... more details
Pentosyltransferases are a type of glycosyltransferase that catalyze the transfer of a pentose . Examples include adenine phosphoribosyltransferase hypoxanthine guanine phosphoribosyltransferase pertussis toxin poly ADP ribose polymerase They are classified under EC number 2.4.2. External links MeshName Pentosyltransferases Glycosyltransferases enzyme stub Category EC 2.4.2 ... more details
Extracellular adenylate cyclase is an adenylate cyclase produced by Bordetella pertussis . ref name pmid2870055 cite journal author Kessin RH, Franke J title Secreted adenylate cyclase of Bordetella pertussis calmodulin requirements and partial purification of two forms journal J. Bacteriol. volume 166 issue 1 pages 290 6 year 1986 month April pmid 2870055 pmc 214590 doi url http jb.asm.org cgi pmidlookup?view long&pmid 2870055 ref ref name pmid2877986 cite journal author Ladant D, Brezin C, Alonso JM, Crenon I, Guiso N title Bordetella pertussis adenylate cyclase. Purification, characterization, and radioimmunoassay journal J. Biol. Chem. volume 261 issue 34 pages 16264 9 year 1986 month December pmid 2877986 doi url http www.jbc.org cgi pmidlookup?view long&pmid 2877986 ref References reflist Phosphorus oxygen lyases Toxins Category EC 4.6.1 enzyme stub ... more details
cyclase toxin of Bordetella pertussis binds to target cells via the alpha M beta 2 integrin CD11b CD18 ... Bordatella pertussis adenylate cyclase a toxin with multiple talents journal Trends Microbiol. volume ... messenger to initiate a change in cell function. ref name pmid16138079 See also pertussis toxin ... more details
Diphtheria vaccine class1 Vaccine component2 Pertussis vaccine class2 Vaccine component3 Tetanus ... diphtheria , pertussis whooping cough and tetanus . The vaccine components include diphtheria and tetanus toxoids, and killed whole cells of the organism that causes pertussis wP . DTaP also known as Tdap , DTPa , and TDaP refers to similar combination vaccines in which the pertussis component is acellular . Also available is the DT or TD vaccine , which lacks the pertussis component. In the Netherlands ... . There, pertussis is known as kinkhoest and DKTP refers to a combination vaccine against diphtheria, pertussis kinkhoest, tetanus, and polio. The usual course of childhood immunization ... the relative concentrations of their components. Combination vaccines with whole cell pertussis While pertussis was thought to have been eradicated entirely from the United States, in recent ... J, Ross E title Pertussis vaccine and whooping cough as risk factors in acute neurological illness ... to whole cell DPT injection are thought to be from the pertussis component. In 1994, the Institute ... pertussis vaccine, the evidence was compatible with the possibility that it could be the cause of permanent ... up to 40 C 105 F , and an unusual, high pitched crying. Since 2002, whole cell pertussis vaccines are no longer used in the US. Combination vaccines with acellular pertussis DTaP DTaP also DTPa and TDaP is a combined vaccine against diphtheria, tetanus, and pertussis, in which the pertussis component ... uses selected antigens of the pertussis pathogen to induce immunity. Because it uses fewer antigens ... in Japan in 1981. Tdap pertussis toxoid? Tdap , sometimes known as dTap , ref Hong Kong ... 24 ref is the acronym for the collective vaccines preventing tetanus , diphtheria , and pertussis ... case d and p , the concentration of diphtheria and pertussis toxoids has been reduced in these adult ... that the pertussis toxoids are acellular . Two Tdap vaccines are available in the U.S. Adacel, manufactured ... more details
E title The O Antigen Enables Bordetella parapertussis To Avoid Bordetella pertussis Induced Immunity ... humans and is responsible for a minority of cases of the disease pertussis also known as whooping cough . ref name Cherry 1996 cite journal author Cherry J title Historical review of pertussis and the classical ... more details
ptx may refer to Ptx Unix ptx , a Unix program producing a permuted index Pertussis toxin , an inhibitor of G protein coupled receptors Picrotoxin , a poisonous crystalline plant alkaloid Pneumothorax , a medical condition Parallel Thread Execution , an intermediary assembler language between high level code and that which is sent to the GPU in Nvidia s CUDA programming model disambig de PTX it PTX pl PTX ... more details
holmesii B. holmesii br Bordetella parapertussis B. parapertussis br Bordetella pertussis B. pertussis .... Three species are human pathogen s Bordetella pertussis B. pertussis , Bordetella parapertussis ... edition 4th publisher McGraw Hill year 2004 isbn 0838585299 ref B. pertussis and occasionally B. parapertussis cause pertussis or whooping cough in humans, and some B. parapertussis strains ... , B. pertussis and B. parapertussis and the pathogenesis of respiratory disease caused by these bacteria has been reviewed. ref name Hewlett 1997 cite journal author Hewlett E title Pertussis current ... of respiratory infections due to Bordetella pertussis and other Bordetella subspecies journal ... filamentous haemaglutinin , pertactin , fimbriae , and pertussis toxin though expression of pertussis toxin is unique to B. pertussis . As well as assisting in adherence to epithelial cells, some of these are also ... cells by Bordetella pertussis journal Mol. Microbiol. volume 53 issue 6 pages 1709 19 year 2004 ... GM, Gray MC title Macrophage cytotoxicity produced by adenylate cyclase toxin from Bordetella pertussis ... is present in B. pertussis , B. parapertussis and B. bronchiseptica and is responsible for phase ... pertussis BvgAS signal transduction cascade journal Proc Natl Acad Sci USA volume 91 issue 3 pages ... activation of virulence regulated genes in Bordetella pertussis journal EMBO J volume 15 issue ... pertussis journal J Bacteriol volume 177 issue 10 pages 2727 36 year 1995 pmid 7751282 pmc 176943 ref ... regulation of the vir repressed genes vrg genes in Bordetella pertussis journal J Bacteriol volume 175 ... more details
and pertussis ref name vaccineplace DAPTACEL DTaP diphtheria, tetanus and pertussis ref name vaccineplace Diphtheria and Tetanus Toxoids Adsorbed USP , diphtheria, tetanus and pertussis ref name vaccineplace Tetanus Toxoid Adsorbed diphtheria, tetanus and pertussis ref name vaccineplace TriHIBit DTaP Hib Booster Use diphtheria, tetanus and pertussis and haemophilus influenzae type b ref name vaccineplace Tripedia DTaP vaccine diphtheria, tetanus, pertussis ref name vaccineplace ActHIB haemophilus ... more details
Bordet Gengou agar is a type of agar plate optimized to isolate Bordetella , containing blood, potato extract, and glycerol, with an antibiotic such as cephalexin or penicillin and sometimes nicotinamide. ref name MM cite book title Medical Microbiology, 4th edition editor Samuel Baron chapter Bordetella author Horst Finger and Carl Heinz Wirsing von Koenig publisher University of Texas Medical Branch at Galveston date 1996 isbn 0 9631172 1 1 http www.ncbi.nlm.nih.gov bookshelf br.fcgi?book mmed&part A1712 ref The potato extract provided nitrogen and vitamins, and potato starch absorbed fatty acids present in nasal secretions or collection swab cotton that inhibited growth glycerol was a carbon source. ref name BD http www.bd.com europe regulatory Assets IFU HB CE PA PA 254400.pdf BD Bordet Gengou Agar with 15 Sheep Blood product insert also describing Bordetella Agar with Charcoal ref Medical Microbiology, 4th edition ref name MM states that Regan Lowe medium ref name BD containing charcoal, blood, and antibiotic has replaced Bordet Gengou medium as the medium of choice for routine Bordetella pertussis incubation. Bordetella bacteria were difficult to culture Jules Bordet and Octave Gengou invented the first version in order to isolate the bacillus, named Bordet Gengou in 1906, that they believed was associated with whooping cough. In 1909 it was not yet established that the bacillus was solely the cause. ref cite journal unused data DUPLICATE DATA title THE BORDET GENGOU BACILLUS OF PERTUSSIS title The Journal of Experimental Medicine author Martha Wollstein date January 9, 1909 http jem.rupress.org content 11 1 41.abstract ref References ref name pmid2906642 cite journal author Kurzynski TA, Boehm DM, Rott Petri JA, Schell RF, Allison PE title Comparison of modified Bordet Gengou and modified Regan Lowe media for the isolation of Bordetella pertussis and Bordetella parapertussis journal J. Clin. Microbiol. volume 26 issue 12 pages 2661 3 year 1988 month December ... more details
DTP is an acronym which can be used to refer to Computing Distributed transaction processing , in computer systems, usually refers to the X Open model of co ordinating transactions between multiple participants Desktop publishing , a technological publishing method Dynamic Trunking Protocol Digital teaching platform , educational series of products designed to operate in a teacher led classroom. Medicine Another name for the DPT vaccine , a triple vaccine used to inoculate against diphtheria, tetanus, and pertussis Developmental Therapeutics Program of the National Cancer Institute Distal Tingling on Percussion medicine see Tinel sign Tinel s sign Other uses Demokratik Toplum Partisi, the Turkish name for the Democratic Society Party D.T.P. , an album by Sadus Devin Townsend Project Disturbing tha Peace , a record label and management company disambig ca DTP da DTP de DTP fr DTP ko DTP it DTP nl DTP tr DTP zh DTP ... more details
The abbreviation DPT can refer to The Democratic Party of Turkmenistan The DPT vaccine Diphtheria Pertussis Tetanus vaccine The Democratic peace theory Democratic Peace Theory Dioptre , most commonly a unit measuring refraction in a lens or curved mirror Dipropyltryptamine , a psychedelic Doctor of Physical Therapy degree Pok mon Diamond and Pearl Pok mon Diamond, Pearl and Pok mon Platinum Platinum DPt , a trilogy of video game s for the Nintendo DS Dirty Pretty Things band , a band founded in 2005 Dirty Pretty Things film , a movie released in 2002 Dynamic Packet Transport Dynamic Preemption Threshold scheduling algorithm Dublin Port Tunnel Dual Port Transceiver , a computer networking device Dumbarton People s Theatre disambig de DPT fa DPT it DPT ... more details
A heterologous vaccine is a type of live vaccine where one virus is introduced to provide protection against another virus. An example is the administration of vaccinia to provide protection against variola . Like all live vaccines, it has the advantage that it replicates in the body, and therefore reduces the need for booster shots. It has the disadvantage that a potential pathogen is introduced into the body. It can be combined with the attenuation strategy in vaccine design. ref name pmid17954727 cite journal author Ho SY, Chua SQ, Foo DG, et al. title Highly attenuated Bordetella pertussis strain BPZE1 as a potential live vehicle for delivery of heterologous vaccine candidates journal Infect. Immun. volume 76 issue 1 pages 111 9 year 2008 month January pmid 17954727 pmc 2223651 doi 10.1128 IAI.00795 07 url http iai.asm.org cgi pmidlookup?view long&pmid 17954727 ref References Reflist Vaccines Category Vaccination Category Virology vaccine stub ... more details
likely to be infected by B. pertussis or Bordetella parapertussis B. parapertussis . B. bronchiseptica does not express pertussis toxin , which is one of the characteristic virulence factors of B. pertussis . But it has the genes to do so, highlighting the close evolutionary relationship between ... LM, Brinig MM, Relman DA, Mooi FR title Bordetella pertussis , the Causative Agent of Whooping Cough ... Projects B pertussis Genetic sequences of the Bordetella bronchiseptica complex Sanger ... more details
Unreferenced date March 2009 Louis Wendlin Sauer 1885 1980 was a pediatrician who became known for perfecting the vaccine used to prevent pertussis Whooping cough , saving countless lives around the world. Sauer was born in Cincinnati, met his wife Mira while he was in Germany as he was a medical student, and established a practice at Evanston Hospital , in Evanston, a suburb of Chicago, Illinois. He earned an MD in Berlin and his PhD at the University of Chicago. He was a founder of The Cradle adoption agency in Evanston. He taught at the Northwestern University Medical School, Chicago. He retired in 1959 to Coral Gables, Florida and died at age 94 of pneumonia and congestive heart failure . written by Robertson Adams, great grandchild of the subject and based on reference from NY Times and obituary appearing in the Miami Herald. Very carefully written to include no copyrighted or copy paste information. Persondata Metadata see Wikipedia Persondata . NAME Sauer, Louis W ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH 1885 PLACE OF BIRTH DATE OF DEATH 1980 PLACE OF DEATH DEFAULTSORT Sauer, Louis W Category 1885 births Category 1980 deaths Category American pediatricians Category Deaths from congestive heart failure Category Deaths from pneumonia Category The Cradle Category People from Cincinnati, Ohio US med bio stub ... more details
Unreferenced date June 2009 Health in Angola is rated among the worst in the world. Angola lies in the yellow fever endemic zone. Cholera incidence is high. Only a small fraction of the population receives even rudimentary medical attention. As of 2004, the ratio of physicians per population was estimated at 7.7 per 100,000 people. In 2005, average life expectancy was estimated at only 38.43 years, one of the lowest in the world. That year infant mortality was estimated at 187.49 per 1,000 live births, the highest in the world. The incidence of tuberculosis in 1999 was 271 per 100,000 people. Immunization rates for one year old children in 1999 were estimated at 22 for diphtheria , pertussis , and tetanus and 46 for measles . Malnutrition affected an estimated 53 of children under five years of age as of 1999. From 1975 to 1992, there were 300,000 civil war related deaths. The overall death rate was estimated at 24 per 1,000 in 2002. The HIV AIDS prevalence was 3.90 per 100 adults in 2003. As of 2004, there were approximately 240,000 people living with HIV AIDS in the country. There were an estimated 21,000 deaths from AIDS in 2003. In 2000, 38 of the population had access to safe drinking water and 44 had adequate sanitation. Africa in topic Health in Category Health in Angola Angola stub fr Sant en Angola ... more details
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