The northernblot is a technique used in molecular biology research to study gene expression by detection ... Protocol. Biochem. and Biophys. Research Comm. 238 277 279. ref Image NorthernBlot Scheme.PNG thumb ... 2008 title BlotBase A northernblot database url journal Gene volume 427 issue 1 2 pages 47 50 doi 10.1016 ... target sequence. The term northernblot actually refers specifically to the capillary transfer .... Nutrition Soc. 55 583 589. ref The northernblot technique was developed in 1977 by James Alwine ... synthase Cloning and sequencing of the cDNA and Northernblot analysis url journal Eur. J. Biochem ... C. W. last3 Erkan first3 M. last4 Kleef first4 J. last5 Friess first5 H. year 2009 title Northernblot ... for comparison in a northernblot, samples not displaying the gene product of interest can be used ... and specific detection of microRNAs by northernblot analysis using LNA modified oligonucleotide probes ... Weising first4 K. year 1996 title Northernblot analysis of simple repetitive sequence transcription ... sequence of interest to act as the probe in the northernblot. ref name Liang1995 Liang, P. Pardee ... Problems in Nonradioactive Northern and Southern Blot Analysis Enables Higher Sensitivity ... ref If an upregulated gene is observed by an abundance of mRNA on the northernblot the sample ... different tissue types. ref name Schlamp2008 Northern blots can be searched by a blot ID, paper reference ... Quantitative Assessment of DNA Microarrays Comparison with NorthernBlot Analysis url journal Genomics ... name Streit2009 Reverse northernblot A variant of the procedure known as the reverse northernblot ... Differential display References Reflist 2 External links http openwetware.org wiki Northernblot ... Blot es Northernblot eo RNA trimoo fr Northernblot ko it Northernblot he RNA hu Northernblot ja no Northernblot pl Hybrydyzacja northern pt Northernblot sv Northernblot tr Northernblot ... more details
The reverse northernblot is a variant of a northernblot in which the nucleic acid immobilized on a membrane is a collection of isolated DNA fragments rather than RNA , and the molecular probe probe is RNA extracted from a tissue and radioactively labelled. DNA microarrays use methods akin to the reverse procedure, in that they involve the use of isolated immobilized DNA fragments, and hybridization with a probe made from cellular RNA. Thus the reverse northernblot, though originally uncommon, enabled northern analysis to evolve into gene expression profiling , in which many possibly all of the genes in an organism may have their expression monitored. Category Molecular biology techniques Genetics stub ... more details
wiktionary Blot may refer to Blot biology , method of transferring proteins, DNA, RNA or a protein onto a carrier. In Germanic paganism and Germanic neopaganism, a bl t is a sacrifice to the gods or other beings Blot album , an album by Einherjer, referring to the Germanic practice Another name of a trick taking card game Belot Blot Transformers , a character from the Transformers franchise disambiguation de Blot fr Blot ... more details
Infobox Film name The Blot image The Blot dvd cover.jpg image size caption director Phillips Smalley br Lois Weber producer Lois Weber writer Phillips Smalley br Lois Weber br Marion Orth narrator starring Phillip Hubbard br Margaret McWade br Claire Windsor br Louis Calhern br Marie Walcamp music cinematography Gordon Jennings editing distributor F.B. Warren Corporation studio Lois Weber Productions released runtime 91 minutes country USA language Silent film br English language English intertitles budget preceded by followed by The Blot is an American silent film silent drama film directed by Lois Weber with her husband Phillips Smalley in 1921 in film 1921 . The film tackles the social problem of genteel poverty , focusing on a starving family. It stars Claire Windsor , Louis Calhern and Marie Walcamp . Weber filmed in real locations, using as much natural lighting as possible. Many supporting roles were given to non professionals. Along with its bleak and unglamorous settings, the film ends on an ambiguous note, in which unrequited love , convenience, and even the characters desperation are all factors. If this is a universe where people live in real, cramped houses with thread bare carpets, then their need for security and desire for comfort supersedes their want for true love. The film also suggests that something greater than charity is needed to aid the impoverished. Scenes were filmed on location around Los Angeles, particularly at the old University of Los Angeles campus, now Los Angeles City College . The Blot was restored by Kevin Brownlow and David Gill film historian ... Behind the Mask of Innocence 1990 . The Blot , which is currently available on DVD and VHS , was exhibited ... imdb title id 0011979 Amg movie 6210 The Blot commonscat DEFAULTSORT Blot, The Category 1921 films ... Black and white films Category 1920s drama films Category Films directed by Lois Weber ca The Blot es The Blot it The Blot ... more details
image DotBlotDemo.jpg right thumb 350px Schematic of the use of two Allele specific oligonucleotide ASO probes on duplicate Dot blot filters. A Dot blot or Slot blot is a technique in molecular biology used to detect biomolecule s. It represents a simplification of the northern blot , Southern blot , or western blot methods. In a dot blot the biomolecule s to be detected are not first separated by chromatography . Instead, a mixture containing the molecule to be detected is applied directly on a membrane as a dot. This is then followed by detection by either nucleotide Hybridization probe probes for a northern blot and Southern blot or antibody antibodies for a western blot . The technique offers significant savings in time, as chromatography or gel electrophoresis , and the complex blotting procedures for the gel are not required. However, it offers no information on the size of the target biomolecule . Furthermore, if two molecule s of different sizes are detected, they will still appear as a single dot. Dot blots therefore can only confirm the presence or absence of a biomolecule or biomolecule s which can be detected by the DNA Hybridization probe probes or the antibody . A radioactive sample can be Nucleic acid hybridisation hybridized to allow for the detection of variation between samples. The DNA is quantified and equal amounts are aliquoted into tubes in excess of the number of its targets in the samples, such as 10 g for a plasmid and 1 g for a PCR amplicon. These are denatured NaOH and 95 C and added to the wells where a vacuum sucks the water with NaOH and NH sub 4 sub OAc from underneath the membrane nylon or nitrocellulose . See also Southern blot Northern blot Western blot Southwestern blot External links http www.bio rad.com cmc upload Literature 12484 M1706542C.pdf A protocol for the BioRad Dot Blot Apparatus biology stub Category Molecular biology es Dot Blot fr Dot blot it Dot blot tr Dot blot ... more details
In molecular biology and genetics , a blot is a method of transferring protein s, DNA or RNA , onto a carrier for example, a nitrocellulose PVDF or nylon membrane . In many instances, this is done after a gel electrophoresis , transferring the molecules from the gel onto the blotting membrane, and other times adding the samples directly onto the membrane. After the blotting, the transferred proteins, DNA or RNA are then visualized by one or more different methods colorant staining for example, silver staining of proteins autoradiography autoradiographic visualization of radioactive labelled molecules performed before the blot specific labelling of some proteins or nucleic acid s. It is done with antibody antibodies or hybridization probe s that bind only to some molecules of the blot and have an enzyme joined to them. After proper washing, this enzymatic activity and so, the molecules we search in the blot is visualized by incubation with proper reactive, rendering either a colored deposit on the blot or a chemiluminiscence chemiluminiscent reaction which is registered by photographic film . Common blot methods are Southern blot for DNA Southwestern blot for Protein DNA Northernblot for RNA Reverse Northernblot for RNA Western blot for protein s Far Western blot for Protein Protein Eastern blotting for posttranslational modification Far Eastern blot for Lipids , Drugs and Hormones Dot blot Slot blot See also Immunoscreening External links http www.westernblotting.org Western Blot Protocols and Troubleshooting Category Molecular biology Category Laboratory techniques de Blotting fa fr Transfert biologie mol culaire pl Blotting DNA ru ... more details
Infobox French commune name Blot l glise region Auvergne region Auvergne department Puy de D me arrondissement Arrondissement of Riom canton Canton of Menat INSEE 63043 postal code 63440 mayor Jean Luc Blanc term 2008&ndash 2014 intercommunality Communaut de communes du Pays de Menat longitude 2.95555555556 latitude 46.0383333333 elevation m 630 elevation min m 365 elevation max m 748 area km2 25.29 population 386 population date 2006 Blot l glise is a Communes of France commune in the Puy de D me Departments of France department in Auvergne region Auvergne in central France . See also Communes of the Puy de D me department References http www.insee.fr en home home page.asp INSEE Reflist Puy de D me communes DEFAULTSORT Blot L eglise Category Communes of Puy de D me Blotleglise PuyD me geo stub ca Blot l glise ceb Blot l glise es Blot l glise eu Blot l glise fr Blot l glise it Blot l glise ms Blot l glise nl Blot l glise pms Blot l glise pl Blot l glise pt Blot l glise sr uk vi Blot l glise vo Blot l glise war Blot l glise ... more details
A Southern blot is a method routinely used in molecular biology for detection of a specific DNA sequence in DNA samples. Southern blotting combines transfer of agarose gel electrophoresis electrophoresis separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization . The method is named after its inventor, the United Kingdom British biologist Edwin Southern . ref cite journal last Southern first Edwin Mellor authorlink Edwin Southern date 5 November 1975 title Detection of specific sequences among DNA fragments separated by gel electrophoresis journal Journal of Molecular Biology volume 98 issue 3 pages 503 517 issn 0022 2836 doi 10.1016 S0022 2836 75 80083 0 pmid 1195397 ref Other Blot biology blot ting methods i.e., Western blot , ref Towbin et al. Staehelin, T Gordon, J 1979 . Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets procedure and some applications . PNAS 76 9 4350. doi 10.1073 pnas.76.9.4350. PMID 388439. ref Northernblot , Eastern blotting Eastern blot , Southwestern blot that employ similar principles, but using RNA or protein, have later been named in reference to Edwin Southern s name. As the technique was eponym ously named, Southern blot is capitalized as is conventional for proper noun s. The names for other blotting methods may follow this convention, by analogy. ref cite journal last ... enzyme will produce a single band on a Southern blot, whereas multiple bands will likely ... Southern blot OpenWetWare Molecular probes Category Molecular biology techniques ca Transfer ncia Southern cs Southern v p enos de Southern Blot es Southern blot eo DNA trimoo fr Southern blot id Blot Southern it Southern blot he hu Southern blot ja no Southern blot pl Hybrydyzacja Southerna pt Southern blot ru sv Southern blot ta tr Southern blot uk vi Southern blot zh ko ... more details
Western blot was given to the technique by W. Neal Burnette and Sushant Bhat ref name Burnette1981 and is a play on the name Southern blot , a technique for DNA detection developed earlier by Edwin Southern . Detection of RNA is termed Northernblot . Steps in a western blot Tissue preparation Samples ...Image Immunoblot.png thumb right Immunoblot Western blot analysis of proteins separated by SDS PAGE gradientgel ... 1987 pmid 3553936 doi 10.1016 0166 6851 87 90182 4 ref The western blot sometimes called the protein ... Western blot transfer.png center The uniformity and overall effectiveness of transfer of protein ... sites of the specific target protein. This reduces noise in the final product of the western blot ... bound to the blot. A cheaper but less sensitive approach utilizes a 4 chloronaphthol stain ... stain that can be photographed without using specialized photographic film. image Western Blot binding.png ... in signal produced by labeled antibodies bound to proteins on a western blot. Proteins can ... for direct detection after a series of wash steps. Image Blotautoradiogram.png frame Western blot ... blot is ready for detection of the probes that are labeled and bound to the protein of interest. In practical ... detection method depends on incubation of the western blot with a substrate that reacts with the reporter ... stains the membrane. Development of the blot is then stopped by washing away the soluble dye. Protein ... blot with a substrate that will luminesce when exposed to the reporter on the secondary antibody ... a digital image of the western blot. The image is analysed by densitometry, which evaluates the relative .... image Western blot chemiluminescent detection.png center Radioactive detection Radioactive labels ... against the western blot which develops as it is exposed to the label and creates dark regions which ... emission filters which captures a digital image of the western blot and allows further data analysis such as molecular weight analysis and a quantitative western blot analysis. Fluorescence ... more details
Infobox cyclist name Guillaume Blot image Guillaume Blot 2.jpg caption fullname Guillaume Blot nickname birth date birth date and age 1985 25 03 birth place Saint Malo , France height weight currentteam Bretagne Schuller discipline Road role Rider ridertype amateurteams amateuryears proyears 2008&ndash 2010 br 2011&ndash proteams ct COF 2008 br Bretagne Schuller majorwins updated Guillaume Blot born March 28, 1985 in Saint Malo is a French racing cyclist, member of the Bretagne Schuller team. Career Highlights 2011 1st Stage 3, Tour de Normandie 1st GP de Fourmies External links http uk.eurosport.yahoo.com cy teams 5.html COFIDIS cyclists Persondata Metadata see Wikipedia Persondata . NAME Blot, Guillaume ALTERNATIVE NAMES SHORT DESCRIPTION French racing cyclist DATE OF BIRTH 1985 25 03 PLACE OF BIRTH Saint Malo, France DATE OF DEATH PLACE OF DEATH DEFAULTSORT Blot, Guillaume Category French cyclists Category 1985 births Category Living people France cycling bio stub de Guillaume Blot fr Guillaume Blot nl Guillaume Blot ... more details
Unreferenced date December 2009 Infobox Album See Wikipedia WikiProject Albums Name Blot Type studio Artist Einherjer Cover Blot cover.jpg Released 2003 Recorded Genre Viking metal Length 60 09 Label Tabu Recordings Producer Language Norwegian language Norwegian br English language English Reviews Last album Demo Recordings demo Demo br 2002 This album Blot br 2003 Next album Norr n br 2011 Blot is the fourth full length album by the Norway Norwegian black Viking metal band Einherjer . It was released on November 21, 2003, by Tabu Recordings . Track listing Einherjermarsjen 1 38 Ironbound 3 41 Dead Knight s Rite 5 34 Wolf Age 4 44 The Eternally Damned 3 01 Ware Her Venom 5 57 Hammar Haus 8 02 Starkad 4 19 Ride the Gallows 6 48 Ingen Grid 4 06 Berserkergang 5 55 Venomtongue 6 25 Credits Frode Glesnes Singing vocals , guitar , and Keyboard instrument keyboard arrangements Aksel Herl e guitar, bass guitar Gerhard Storesund Drum kit drums Einherjer DEFAULTSORT Blot Album Category Einherjer albums Category 2003 albums 2000s metal album stub no Blot Einherjer album ... more details
Infobox film name The Blot on the Shield image caption director B. Reeves Eason producer writer starring Dick La Reno music cinematography editing distributor Mutual Film released film date 1915 10 18 runtime country Film US language Silent film Silent br English intertitles budget The Blot on the Shield is a 1915 short film directed by B. Reeves Eason . Cast Dick La Reno Vivian Rich Walter Spencer External links imdb title id 0418552 title The Blot on the Shield DEFAULTSORT Blot on the Shield, The Category 1915 films Category 1910s short films Category Films directed by B. Reeves Eason Category American films Category American silent short films Category Mutual Film films Category Black and white films short silent film stub ... more details
Unreferenced date October 2009 A zoo blot or garden blot is a type of Southern blot that demonstrates the similarity between specific, usually protein coding, DNA sequence s of different species. A zoo blot compares animal species while a garden blot compares plant species. In order to understand the degree to which a particular gene is similar from species to species, DNA preparations from a set of species is isolated and spread over a surface. The sequence of interest is labeled and allowed to hybridize to the prepared DNA. Usually, the labeled DNA is marked with a phosphorus Isotopes radioactive isotope of phosphorus . The hybridization is a process that happens spontaneously DNA pairs with complementary strands. The hybridization, however, is not perfect. The hybridization of two strands will happen even when the strands are similar but not identical. This procedure is used to detect similar or exact relationships between the DNA in question and other organisms, so the technique takes advantage of non exact hybridization. It also allows you judge the locations of introns and exons as the latter will be far more conserved than the former. See also Southern blot Fluorescent in situ hybridization Category Genetics Category Laboratory techniques Category Molecular biology molecular biology stub This relies on the conservation of DNA exon sequences between species, hence the name. The theory is that sequences conserved between species are more likely to represent expressed genes or coding sequences. The technique used here is similar to cDNA selection except the cDNA probe is replaced with genomic DNA isolated from different species, lions and unicorns and bears from the city zoo, perhaps. ... more details
In universe date February 2010 Infobox character colour 4B89E6 name The Phantom Blot image File PhantomBlot.gif ... Blot , 1939 creator Floyd Gottfredson with Merrill De Maris , dn Bill Wright date June 2011 and Ted Thwaites lbl1 Voiced by data1 Frank Welker , John O Hurley alias noinfo yes The Phantom Blot is a fictional ... . He first appeared in the Mickey Mouse comic strip adventure Mickey Mouse Outwits The Phantom Blot ... Don Markstein s Toonopedia work Don Markstein accessdate 26 November 2010 ref History The Phantom Blot, or simply The Blot , made his first appearance in Mickey Mouse Outwits The Phantom Blot . In this story ... himself The Blot. According to O Hara, he is the smartest thief they ve ever met. Detective Casey ... Blot date 2003 01 25 work Scoop Where the Magic of Collecting Comes Alive accessdate 20 November ... of the Six Napoleons . In the end, Blot is captured and unmasked. Most later stories featuring ... and writers have furthered the Phantom Blot throughout the years. The first re appearance was in the Italy ... of The Phantom Blot drawn by Paul Murry that ran in issues 284 287 May August 1964 of Walt Disney ... to the Blot and his crimes. He next turned up in the mid 1970s in two issues of Super Goof written ... Blot was unmasked at the end of Mickey Mouse Outwits The Phantom Blot . The Phantom Blot s gaunt face and thin mustaches, as revealed at the end of Mickey Mouse Outwits The Phantom Blot , were ... himself to act as a criminal in order to frame him. He has quite a talent in acting. The Blot often ... watchman, is patrolling the businesses when the Blot realizes he must abort his plans and says I always ..., adding to his reputation. The Blot is, himself, very vain and his desire for money and power ... , and Chief O Hara Disney Comics Chief O Hara have all encountered the Blot, and thus successfully tried to stop him. The Blot sometimes teams up with other bad guys like the Beagle Boys and Mad Madam ... s popularity, he was given his own comic book, The New Adventures of the Phantom Blot , which lasted ... more details
Yvan Blot born 29 June 1948 in Saint Mand is a France French conservative political figure who has been a member of Groupement de recherche et d tudes pour la civilisation europ enne GRECE and the founder and president of the Club de l Horloge . ref cite news url http www.time.com time magazine article 0,9171,948544 1,00.html title Time accessdate 2007 05 09 date August 13, 1979 ref A former Gaullism Gaullist parliamentarian for Rally for the Republic , Blot also served as a leading civil servant under both Minister of the Interior France Interior Minister Michel Poniatowski and Alain Devaquet . ref J.G. Shields, The Extreme Right in France , Abingdon Routlegde, 2007, p. 157 ref He joined the Front National France Front National in 1989 and was elected to the European Parliament for them in the European Parliament election, 1989 1989 election . ref Shields, op cit, p. 242 ref A prominent Eurosceptic he played a leading role in establishing a committee to support the Bruges Group in France. ref G Harris, The Dark Side of Europe The Extreme Right Today, Edinburgh Edinburgh University Press, 1994, p. 224 ref He also played a leading role in FN policy making, joining other Club de l Horloge alumni such as Bruno M gret and Jean Yves Le Gallou in driving the party away from corporatism and towards Neoliberalism neo liberal economics. ref Shields, op cit, pp. 245 6 ref He has also written for Nation Europa magazine. He is now member of the UMP He has two websites and is the founder of the association Agir pour la d mocratie directe in Paris. The mission statement of this assopciation is to change the French constitution on the Swiss model. References Reflist External links http ...?language EN&id 1211 European Parliament Persondata Metadata see Wikipedia Persondata . NAME Blot ... Saint mand Val de Marne France DATE OF DEATH PLACE OF DEATH DEFAULTSORT Blot, Yvan Category 1948 ... MEP stub fr Yvan Blot ... more details
Eskil s death to c. 1016, several generations before Blot Sweyn. ref name Eskil How Sweyn was killed ... is mentioned in other sources as being the son of Blot Sweyn, ref name Nordisk2 cite web url http ... of Sweden ISBN 91 87064 35 9 p. 13 ref s start s hou 1087 name Blot Sven s reg s bef before Inge I ... Monarchs of Sweden Notes references DEFAULTSORT Blot Sweyn Category Swedish monarchs Category Pagan restorations cs Blot Sven de Sven Schweden es Blot Sven fr Sven de Su de it Blot Sven di Svezia lv Blotsvens hu Svend sv d kir ly nl Sven van Zweden no Blot Svein pt Blot Sven da Su cia sv Blot Sven ... more details
Infobox French commune name Saint R my de Blot region Auvergne region Auvergne department Puy de D me arrondissement Arrondissement of Riom canton Canton of Menat INSEE 63391 postal code 63440 mayor Fran ois Roguet term 2008&ndash 2014 intercommunality Communaut de communes du Pays de Menat longitude 2.93138888889 latitude 46.0780555556 elevation m 532 elevation min m 346 elevation max m 665 area km2 15.22 population 209 population date 2006 Saint R my de Blot is a Communes of France commune in the Puy de D me Departments of France department in Auvergne region Auvergne in central France . See also Communes of the Puy de D me department References http www.insee.fr en home home page.asp INSEE Reflist Puy de D me communes DEFAULTSORT Saint Remy De Blot Category Communes of Puy de D me Saintremydeblot PuyD me geo stub ca Saint R my de Blot ceb Saint R my de Blot es Saint R my de Blot eu Saint R my de Blot fr Saint R my de Blot it Saint R my de Blot ms Saint R my de Blot nl Saint R my de Blot pms Saint R my de Blot pl Saint R my de Blot pt Saint R my de Blot uk vi Saint R my de Blot vo Saint R my de Blot war Saint R my de Blot ... more details
Summary album cover fur Article Blot album Use Infobox ADDITIONAL INFORMATION Name Blot Artist Einherjer Label Tabu Recordings Graphic Artist Item Type album Website Owner Commentary OVERRIDE FIELDS Description Album cover of Einherjer s Blot Source Portion Low resolution Purpose Must be specified if Use is not Infobox Header Section Artist Replaceability other information Licensing Non free album cover ... more details
Summary Non free media rationale Article The Blot Description Low resolution image of DVD cover for the 1921 film The Blot Source http www.amazon.com dp B0000E68WC Portion Whole portion of DVD cover, reduced quality Low resolution yes Purpose Solely to illustrate the above film in the article The Blot , enhancing the article by providing an immediate relevance to the reader. Replaceability No known free images of the film other information This image does not limit the copyright holder s ability to profit from the original source. non free video cover ... more details
Diagnostic infobox Name Ink blot test Image Caption ICD10 ICD9 MeshID D007282 OPS301 OtherCodes An Ink blot test is a personality test which involves the evaluation of a subjects response to ambiguous ink blots. Types include Rorschach test Holtzman Inkblot Test Psychologic and psychiatric evaluation and testing Category Personality tests medicine stub ... more details
Wiktionary Northern may refer to the following Geography Northern country subdivision disambiguation Northern country subdivision , various regions, states, territories, etc. Northern Range , a range of hills in Trinidad Northern Highland , a region of Wisconsin, United States Education Northern University disambiguation , various institutions Northern Collegiate Institute and Vocational School NCIVS , a school in Sarnia, Canada Northern Secondary School , a high school in Canada Companies Northern Bank , commercial bank in Northern Ireland Northern Foods , based in Leeds, England Northern Rail , a train operating company in northern England Northern Railway of Canada , a defunct railway in Ontario Northern Records , a Southern California independent record label Northern Store , a food and general merchandise store owned and operated by The North West Company Northern Tool and Equipment Northern Trust , an international financial services company based in Chicago, Illinois Other The Northern pike , fish often called a northernNorthern automobile , an early American automobile Northern genre A genre of Western films set in Canada or Alaska Northern locomotive , a type of 4 8 4 steam locomotive Northern AFC , a soccer club based in Dunedin, New Zealand Bradford Bulls Bradford Northern , former name of the Bradford Bulls, a British rugby league football club See also Special PrefixIndex Northern List of all pages beginning with Northern Eastern disambiguation Southern disambiguation Western disambiguation Severny disambiguation Disambig de Northern fr Northern nl Northern pl Northern pt Northern sv Northern ... more details
Summary Non free use rationale Article Phantom Blot Description The Phantom Blot as depicted in Epic Mickey Source Game opening Portion Whole Screen Low resolution Lower than the original screenshot. Purpose To show how the character is depicted in the game Replaceability There is no free equivalent of this image. Licensing Non free game screenshot Wii ... more details
Northern Railway is the name of North railway Austria Northern Railway California , predecessor of the Southern Pacific Company Northern Railway of Canada Northern Railway Zone India Northern Railway Namibia Nevada Northern Railway Northern Railway Russia Northern Railway Western Australia See also Northern Rail , a train operating company in Northern England Great Northern Railway disambiguation Northern Railroad disambiguation disambig ... more details
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