NIH can refer to National Institutes of Health United States National Institute of Health Pakistan National Institute Of Homoeopathy India, WB Norwegian School of Sport Sciences Not Invented Here a term and label developed in the computer industry referring to organizations incapable of using technology from other organizations. Nih town , an ancient town in Sistan modern Iran and Afghanistan disambig da NIH de NIH fr Nih it NIH he NIH ... more details
An NIH shift is a chemical rearrangement where a hydrogen atom on an aromatic ring undergoes an intramolecular migration primarily during a hydroxylation reaction. This process is also known as a 1,2 hydride shift. These shifts are often studied and observed by isotopic labeling . An example of an NIH shift is shown below Image Gen NIH shift.png 400px center Example of NIH shift In this example, a hydrogen atom has been isotopically labeled using deuterium shown in red . As the hydroxylase adds a hydroxyl the OH group , the labeled site shifts one position around the aromatic ring relative to the stationary methyl group CH sub 3 sub . Several hydroxylase enzymes are believed to incorporate an NIH shift in their mechanism, including 4 hydroxyphenylpyruvate dioxygenase and the tetrahydrobiopterin dependent hydroxylase s. The name NIH shift arises from the U.S. National Institutes of Health from where studies first reported observing this transformation. References cite journal author Guroff, G. Daly, J.W. Jerina, D.M. Renson, J. Witkop, B. Udenfriend, S. title Hydroxylation induced migration the NIH shift. Recent experiments reveal an unexpected and general result of enzymatic hydroxylation of aromatic compounds. journal Science year 1967 volume 157 pages 1524&ndash 1530 pmid 6038165 doi 10.1126 science.157.3796.1524 issue 796 . cite journal author Bassan, A. Blomberg, M.R.A. Siegbahn, P.E.M. title Mechanism of Aromatic Hydroxylation by an Activated FeIV O Core in Tetrahydrobiopterin Dependent Hydroxylases journal Chem. Eur. J. year 2003 volume 9 pages 4055&ndash 4067 pmid 12953191 doi 10.1002 chem.200304768 issue 17 . Category Enzymes Category Posttranslational modification Category Reaction mechanisms zh NIH ... more details
Wikify date January 2011 Nih was a town belonging to the ancient state of Sistan , which straddles the modern border of Afghanistan and Iran. blockquote At some distance to the west of the Zarah lake, on the Kuhistan frontier and close to the border of the Great Desert, is the town of Nih, or N h, which is named by earlier Arab geographers as belonging to S st n. Mu addas mentions it as a strongly fortified town, the houses of which were built of clay, water being brought down from the hills by underground channels. Nih is also referred to by Y t and Mustawf , who, however, add no details, except to state that it was founded by King Ardash r B bg n , though at the present day the remains of great fortifications, and the immense ruins found here, would seem to prove that in the middle ages it had been a place of much importance. ref Guy Le Strange. http books.google.com books?id Q 88AAAAIAAJ&pg PA340&lpg PA340&dq 22ram shahristan 22&source bl&ots nRGfvGaMRI&sig 6FrECPAtRIhC73Z6eD62q80WYW8&hl en&ei 8ly3S uJNoK78gaW35ToBw&sa X&oi book result&ct result&resnum 1&ved 0CAYQ6AEwAA v onepage&q 22ram 20shahristan 22&f false The lands of the eastern caliphate Mesopotamia, Persia, and Central Asia, from the Moslem conquest to the time of Timur . Cambridge geographical series. General editor F. H. H. Guillemard. reprint Publisher CUP Archive, 1930. Originally published 1905. ref blockquote References references DEFAULTSORT Nih Town Category Sistan ... more details
Unreferenced date January 2011 Notability Notability date January 2011 NIH Office of Technology Transfer manages all intramural inventions from the United States National Institutes of Health NIH and Food .... Function and mission The Office of Technology Transfer OTT , manages the wide range of NIH and FDA .... The mission of the NIH OTT is to improve public health through the management of inventions made by NIH and FDA scientists and the development of intellectual property policies for NIH s intramural ... of Health and Human Services HHS . HHS has designated NIH as the lead agency for technology transfer policy matters. OTT, through its Division of Policy, has the lead responsibility for NIH ... Transfer Policy Board. This includes NIH CRADA Subcommittee the review of Cooperative Research and Development Agreements CRADAs negotiated by technology transfer staff at the NIH Institutes and Centers ICs . OTT carries out its technology transfer mandate by managing the inventions made in NIH ... use, commercialization, and public availability. Over the last 20 years, NIH has executed thousands of license agreements. These licenses transfer NIH and FDA inventions to the private sector for further ... transfer at the NIH is at once centralized and decentralized. It is decentralized in that each NIH ... of the NIH Office of the Director OD . OTT comprises the Office of the Director, the Division of Technology ... approved vaccines and therapeutics. The sale of these products by NIH licensees has surpassed ... The NIH Office of Technology Transfer was established in 1989 within the NIH Office of the Director ... and policy function for NIH. Gradually other NIH and FDA technology transfer transactional functions were consolidated within this office renamed as the NIH Office of Technology Transfer , including U.S patent prosecution from the Patent Branch of the NIH Office of General Counsel as well as licensing ... Service NTIS of the U.S. Department of Commerce. To date acting or permanent Directors of the NIH Office ... more details
Image wiki ibs grant graph.gif thumb 300px right Number of researchers receiving NIH grants for study related to Irritable Bowel Syndrome, 1974 2007 ref cite web title NIH CRISP Search Tool, search for phrase Irritable Bowel url http crisp.cit.nih.gov crisp crisp query.generate screen accessdate 2007 09 08 ref In the United States, the National Institutes of Health is the largest single entity providing funding for biomedical research. ref name Medical Research Spending Doubled Over Past Decade http www.medpagetoday.com PublicHealthPolicy HealthPolicy tb 1767 Medical Research Spending Doubled Over Past Decade , Neil Osterweil, MedPage Today, September 20, 2005. ref In 2006 the NIH awarded 53,285 grants totalling 21 billion dollars. ref cite web title TAGGS FY 2006 Annual Report url http taggs.hhs.gov AnnualReport fy2006 overview grantawards.cfm accessdate 2007 09 08 ref Irritable bowel syndrome IBS is a bowel disorder of unknown etiology characterized by abdominal pain with diarrhea and or constipation. An estimated 15 of the US population is estimated to exhibit symptoms of IBS, with an annual ... 2004 pmid 15298528 ref Funding of IBS According to the NIH s CRISP database, 1977 was the first year in which the NIH awarded a grant whose description included the phrase, irritable bowel. ref cite web title NIH CRISP Search Tool, search for phrase Irritable Bowel url http crisp.cit.nih.gov crisp ... shows the number of researchers receiving NIH grant awards for grants including the term irritable bowel for years 1974 to 2007. ref cite web title NIH CRISP Search Tool, phrase search for Irritable Bowel ... screen Bot retrieved archive archivedate 2007 08 31 ref Recent funding In 2006, the NIH funded 56 projects ref name NAMES 2006 cite web title NIH CRISP Search Tool, phrase search for Irritable ... , with a total disbursement of 18,787,710. ref name AMOUNTS 2006 cite web title NIH Award Database url ... class wikitable collapsible collapsed width 100 colspan 6 List of NIH Funded Research Projects Referring ... more details
NIH stroke scale abbreviated NIHSS ref name pmid10548669 cite journal author Lyden P, Lu M, Jackson C, et al. title Underlying structure of the National Institutes of Health Stroke Scale results of a factor analysis. NINDS tPA Stroke Trial Investigators journal Stroke volume 30 issue 11 pages 2347 54 year 1999 month November pmid 10548669 doi url http stroke.ahajournals.org cgi pmidlookup?view long&pmid 10548669 ref ref name pmid17709996 cite journal author Glymour MM, Berkman LF, Ertel KA, Fay ME, Glass TA, Furie KL title Lesion characteristics, NIH stroke scale, and functional recovery after stroke journal Am J Phys Med Rehabil volume 86 issue 9 pages 725 33 year 2007 month September pmid 17709996 doi 10.1097 PHM.0b013e31813e0a32 url http meta.wkhealth.com pt pt core template journal lwwgateway media landingpage.htm?issn 0894 9115&volume 86&issue 9&spage 725 ref is a scale developed by NINDS that communicates several different neurological deficits ref name pmid10548670 cite journal author Woo D, Broderick JP, Kothari RU, et al. title Does the National Institutes of Health Stroke Scale favor left hemisphere strokes? NINDS t PA Stroke Study Group journal Stroke volume 30 issue 11 pages 2355 9 year 1999 month November pmid 10548670 doi url http stroke.ahajournals.org cgi pmidlookup?view long&pmid 10548670 ref upon a single axis, represented by a score from 0 to 30. A score of more than approximately 25 indicates a large stroke, and a score of less than 4 may still indicate a small stroke. See also Mini mental state examination References reflist External links http www.ninds.nih.gov doctors NIH Stroke Scale.pdf http strokecenter.stanford.edu scales nihss.html medicine stub Neuro procedures Category Stroke Category Medical scales Stroke Category Psychiatric instruments cognitive impairment and dementia Category Psychiatric instruments geriatric psychiatry ... more details
Refimprove date February 2009 Disputed date February 2009 The NIH classification of headaches consists of brief, relatively vague glossary type definitions of a limited number of headaches. ref cite book title Comprehensive Review of Headache Medicine authors Morris Levin, Steven M. Baskin, Marcelo E. Bigal publisher Oxford University Press US year 2008 isbn 0195366735 page 60 ref It outlines five types of headache vascular, myogenic muscle tension , cervicogenic, traction, and inflammatory. Vascular main vascular headache The most common type of vascular headache is migraine . Migraine headaches are usually characterized by severe pain on one or both sides of the head, an upset stomach, and, for some people, disturbed vision. It is more common in women. While vascular changes are evident during a migraine, the cause of the headache is neurological , not vascular. After migraine, the most common type of vascular headache is the Toxic headache toxic headache produced by fever. Other kinds of vascular headaches include cluster headache s , which are very severe recurrent short lasting headaches, often located through or around either eye and often wake the sufferers up at the same time every night. Unlike migraines, these headaches are more common in men than in women. Muscular myogenic Muscular or myogenic headaches appear to involve the tightening or tensing of facial and neck muscles they may radiate to the forehead. Tension headache is the most common form of myogenic headache. Cervicogenic Cervicogenic headaches originate from disorders of the neck, including the anatomical structures innervated by the cervical roots C1 C3. Cervical headache is often precipitated by neck movement and or sustained awkward head positioning. It is often accompanied by restricted cervical range of motion, ipsilateral neck, shoulder, or arm pain of a rather vague non radicular nature or, occasionally, arm pain of a radicular nature. Traction inflammatory Image PET3.jpg right thumb 150px ... more details
Summary NIH funding for IBS in 2005 from http grants.nih.gov grants award trends AggregateData.cfm Licensing self GFDL cc by sa 2.5,2.0,1.0 migration relicense ... more details
Summary NIH Funding for IBS in 2006 from http grants.nih.gov grants award trends AggregateData.cfm Licensing self GFDL cc by sa 2.5,2.0,1.0 migration relicense ... more details
Summary Image taken with Canon Powershot S3 on Nikon TS100 inverted microscope by the author using phase contrast microscopy. Licensing self GFDL cc by 2.5 migration relicense ... more details
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Summary CFTR cartoon from 1989 Journal of NIH Research, defunct since 1997 but previously an NIH US government publication Licensing PD USGov NIH ... more details