Context date October 2009 Infobox disease Name Mediastinaltumor Image Primitive neuroepithelium intermed ... and cyst. Many signs and symptoms of a mediastinaltumor do not distinguish between these two principal classes of mediastinaltumor. However, on a radiograph usually the former class will have an irregular ... anterior mediastinaltumor 20 in adults but rarely seen in children. It can be classified as lymphocytic ... can include thymoma , lymphoma , pheochromocytoma and germ cell tumor s including teratoma ... mediastinal compartment, also known as anterosuperior compartment , is anterior to the pericardium . Masses ... author Macchiarini P, Ostertag H title Uncommon primary mediastinal tumours journal Lancet Oncol ... concerning mediastinal tumors the author writes According to Christian sup 1 sup the mediastinal ... with a mediastinal teratoma including dermoid cyst will cough up hair. ref name Cabot1919 ... gravis symptoms 5,6 . Lymphoma Main lymphoma Image Primary mediastinal large B cell lymphoma very high mag.jpg thumb right Micrograph of a primary mediastinal large B cell lymphoma , a rare type of lymphoma that arises in the mediastinum . H&E stain . Second most common primary anterior mediastinal ... lymphoma non Hodgkin s in all age groups. Can also be primary mediastinal B cell lymphoma with exceptionally ... diagnosis of primary mediastinal B cell lymphoma identifies a clinically favorable subgroup ... journal author Rodr guez J, Guti rrez A, Piris M title Primary mediastinal B cell lymphoma treatment ... mediastinal large B cell lymphoma journal Oncologist volume 11 issue 5 pages 488 95 year 2006 month ... . FNA biopsy is usually not adequate. 12,13,14 Treatment of mediastinal Hodgkin s involves chemotherapy ... better prognosis. Surgery is generally not performed because of invasive nature of tumor. Of all lymphoproliferative disorders cancers involving the same class of blood cell , 2 of cases are mediastinal ... Book on Tumour of Hematopoietic and Lymphoid Tissues. 2001, p. 2001. page 283 ref See also Mediastinal ... more details
s syndrome Hematologic Neoplasia Evaluation and Staging The diagnosis of a mediastinal germ cell tumor should be considered in all young males with a mediastinal mass. In addition to physical ...No footnotes date April 2010 Cleanup date May 2007 Malignant mediastinal germ cell tumors of various histologies were first described as a clinical entity approximately 50 years ago. When date April 2010 mediastinum Mediastinal and other extragonadal germ cell tumors were initially thought to represent isolated metastasis metastases from an inapparent gonads gonadal primary site. Etiology Some investigators suggest that this distribution arises as a consequence of abnormal migration of germ cells during embryogenesis . Others hypothesize a widespread distribution of germ cells to multiple sites during normal embryogenesis, with these cells conveying genetic information or providing regulatory functions at somatic sites. Epidemiology Malignant germ cell tumors of the mediastinum are uncommon, representing only 3 to 10 of tumors originating in the mediastinum. They are much less common than germ cell tumors arising in the testes , and account for only 1 to 5 of all germ cell neoplasm s. Clinical Characteristics Unlike benign germ cell tumors of the mediastinum, malignant mediastinal tumors are usually symptomatic at the time of diagnosis. Most mediastinal malignant tumors are large and cause ..., and determination of serum levels of HCG and alpha fetoprotein. Treatment Pure mediastinal ..., the cardiotoxicity of mediastinal radaition is substantial and the standard treatment of mediastinal ... resection followed by chemotherapy. should this be removed as medical advice? The treatment for mediastinal ... of the Thorax http www.health.am cr malignant germ cell tumors Malignant Mediastinal Germ Cell Tumors .... VAB 3 combination chemotherapy in primary mediastinal germ cell tumors. Cancer Treat Rep 1982 66 1405 ... staging. Cancer 1997 80 681 90. See also Mediastinitis Mediastinal fibrosis Mediastinum Respiratory ... more details
Image Primary mediastinal large B cell lymphoma very high mag.jpg thumb right Micrograph of a primary mediastinal large B cell lymphoma , a cause of mediastinal lymphadenopathy. H&E stain . Mediastinal lymphadenopathy or mediastinal adenopathy is an enlargement of the mediastinal lymph nodes . Causes Tuberculosis Sarcoidosis Cystic fibrosis Histoplasmosis Acute lymphoblastic leukemia Coccidioidomycosis Lymphoma ref http emedicine.medscape.com article 956340 overview ref See also Mediastinum Mediastinal mass Neoplasia References reflist Category Medical signs medical stub ... more details
Image Hidradenoma.jpg thumb 200px Neoplasm Neoplastic tumor of the cheek skin, here a benign neoplasm of the sweat glands called Hidradenoma , which is not solid but is fluid filled. Deleted image removed Image Tumor after operation.jpg thumb 200px Tumor after operation A tumor or tumour is commonly ... eight 000112106 Tumor ref Tumor is not synonymous with cancer . While cancer is by definition malignant, a tumor can be Benign neoplasm benign , pre malignant , or malignant , or can represent a lesion without any cancerous potential whatsoever. Etymology The term tumour tumor is derived from the Latin word for swelling tumor . It is similar to the Old French tumour contemporary French tumeur . In the Commonwealth the spelling tumour is commonly used, whereas in the U.S. it is usually spelled tumor ... of acute inflammation as tumor , Pain dolor , calor , and rubor swelling, pain, increased heat, and redness ... of the movable type printing press . In contemporary English, the word tumor is often used as a synonym for a cystic liquid filled growth or solid neoplasm cancerous or non cancerous , ref Tumor ... present as a tumor. Examples are arteriovenous fistulae or aneurysms with or without thrombosis , biliary ... of types of tumor in which the leakage of their contents would potentially be catastrophic. When ... excision in an attempt to avoid such severe complications. The nature of a tumor is determined ... Swelling medical References references External links wiktionary tumor tumour http www.skintumor.info ... Anatomical pathology Category Medical signs Category Oncology ar bs Tumor bg ca Tumor ceb Tumor cs Tumor da Tumor de Tumor es Tumor eo Tumoro eu Tumore fa fr Tumeur gl Tumor ko hi hr Novotvorina io Tumoro id Tumor it Tumore he kk ku T mor la Tumor lt Auglys hu Daganat ms Tumor nl Tumor ja no Svulst ps pl Guz medycyna pt Tumor ro Tumoare qu Q umpuyasqa ru sco Clyre scn Tumuri simple Tumour sk N dor sl Tumor sh Tumor fi Kasvain sv Tum r ta ... more details
Expert subject Medicine date November 2008 Infobox disease Name Mediastinal fibrosis Image Caption DiseasesDB 30764 ICD10 ICD9 ICD9 519.3 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Mediastinal fibrosis is a rare late complication of histoplasmosis . It is characterized by invasive, calcified fibrosis centered on lymph nodes that block major vessels and airways. ref cite journal author Davis AM, Pierson RN, Loyd JE title Mediastinal fibrosis journal Seminars in respiratory infections volume 16 issue 2 pages 119 30 year 2001 pmid 11521244 doi 10.1053 srin.2001.24242 ref See also Mediastinum Mediastinitis References references External links Chorus 00762 Category Respiratory diseases Category Lymphatic system disease stub ... more details
Infobox Anatomy Name Mediastinal pleura Latin p. mediastinalis GraySubject 238 GrayPage 1088 Image Gray968.png Caption A transverse section of the thorax , showing the contents of the middle and the posterior mediastinum . The pleural cavity pleural and pericardial cavity pericardial cavities are exaggerated since normally there is no space between parietal and visceral pleura and between pericardium and heart . Image2 Caption2 System Precursor MeshName MeshNumber DorlandsPre p 24 DorlandsSuf 12646763 Different portions of the parietal pleura have received special names which indicate their position thus, that portion which lines the inner surfaces of the ribs and Intercostales is the costal pleura that clothing the convex surface of the diaphragm is the diaphragmatic pleura that which rises into the neck, over the summit of the lung, is the cupula of the pleura cervical pleura and that which is applied to the other thoracic viscera is the mediastinal pleura . External links SUNYAnatomyFigs 19 02 03 GPnotebook 1657798715 NormanAnatomy thoraxlesson2 UMichAtlas lung pleura LoyolaMedEd Grossanatomy thorax0 thor lec thor6.html Gray s Thoracic cavity Category Pleura respiratory stub ... more details
Infobox Anatomy Name Mediastinal surface of lung Latin facies mediastinalis pulmonis GraySubject 250 GrayPage 1095 Image Illu quiz lung02.jpg Caption 1. Anterior border of lung Anterior border BR 2. Mediastinal part BR 3. Medial surface BR 4. Inferior lobe BR 5. Base of lung Image2 Caption2 System MeshName MeshNumber DorlandsPre f 01 DorlandsSuf 12352254 The mediastinal surface of the lung is in contact with the mediastinal pleura . It presents a deep concavity, the cardiac impression on lung cardiac impression , which accommodates the pericardium this is larger and deeper on the left lung than on the right lung , on account of the heart projecting farther to the left than to the right side of the median plane. External links GPnotebook 1678114875 SUNYAnatomyFigs 19 05 00 Mediastinal surface of the right lung. Gray s Lung Category Lung anatomy respiratory stub ... more details
Infobox Disease Name Pancoast tumor Image Pancoast Tumor 1.jpg Caption Chest radiograph showing a Pancoast tumor labeled as P, non small cell lung carcinoma, right lung , from a 47 year old female smoker. DiseasesDB 31266 ICD10 ICD10 C 34 1 c 30 ICD9 ICD9 162.3 ICDO OMIM MedlinePlus eMedicineSubj med eMedicineTopic 3418 MeshID D010178 A Pancoast tumor , also called a pulmonary sulcus tumor or superior sulcus tumor , is a lung cancer tumor of the lung pulmonary apex. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung . It typically ... cancers. The growing tumor can cause compression of a brachiocephalic vein , subclavian artery , phrenic ..., fever, weight loss and fatigue, Pancoast tumor can include a complete Horner s syndrome in severe ... pain and weakness in the muscles of the arm and hand . The tumor can also compress the left recurrent ... syndrome , obstruction of the superior vena cava by a tumor mass effect causes facial swelling, cyanosis and dilatation of the veins of the head and neck. A Pancoast tumor is an apical tumor that is typically ..., rapid onset of clinical signs and symptoms, and pleuritic pain can suggest an apical tumor. A Pancoast tumor can give rise to both Pancoast syndrome and Horner s syndrome. When the brachial plexus ... of the brachial plexus , ribs and vertebral bodies , as well as mediastinal lymphadenectomy . Surgical ... watch?v x67dV8n7asI gallery Image Pancoast Tumor 2.jpg CT scan showing a Pancoast tumor labeled ... references External links eMedicine radio 515 Pancoast Tumor http meded.ucsd.edu isp 1994 im quiz pancoast.htm Pancoast Tumor UCSD Xray http www.cancer.gov Templates db alpha.aspx?CdrID 44446 Pulmonary sulcus tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Respiratory tract neoplasia Category Lung cancer ca Tumor de Pancoast de Pancoast Tumor es S ndrome de Pancoast ... pt Tumor de Pancoast ru ... more details
Tumor initiation is a process in which normal cells are changed so that they are able to form tumor s. It is the first phase in tumor development. Substances that cause cancer can be tumor initiators. See also Tumor promotion Tumor progression External links http www.cancer.gov Templates db alpha.aspx?CdrID 390314 Tumor initiation entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Carcinogenesis Oncology stub ... more details
A primary tumor is a tumor growing at the anatomical site where tumor progression began and proceeded to yield a cancerous mass. References Weinberg, Robert. The Biology of Cancer, 2007. Category Types of neoplasia disease stub de Prim rtumor ... more details
Vascular tumor may mean tumor of vascular origin , a growth Benign tumor benign or malignant formed from blood vessel s for example, hemangioma , Lymphangioma , hemangioendothelioma , Kaposi sarcoma , angiosarcoma , etc. a highly vascularized tumor or poorly vascularized tumor , referring to the degree of adequate or inadequate ischemic blood supply to a tumor formed from any biological tissue disambig ... more details
Tumor promotion is a process in which existing tumors are stimulated to grow. It is the second phase in tumor development. Tumor promoters are not able to cause tumors to form. See also Tumor initiation Tumor progression External links http www.cancer.gov Templates db alpha.aspx?CdrID 390316 Tumor promotion entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Carcinogenesis Oncology stub ... more details
A stromal tumor is a tumor that arises in the supporting connective tissue of an organ. External links http www.cancer.gov Templates db alpha.aspx?CdrID 44929 Stromal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia Oncology stub ... more details
unreferenced date October 2011 Tumor progression is the third and last phase in tumor development. This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur. Together with the progression, more and more aneuploidy occurs. This leads to expression in cell and nuclear polymorphism. See also Tumor initiation Tumor promotion External links http www.cancer.gov Templates db alpha.aspx?CdrID 390316 Tumor progression entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Carcinogenesis Oncology stub ... more details
Tumor antigen is an antigen ic substance produced in tumor Cell biology cells , i.e., it triggers an immune response in the Host biology host . Tumor antigens are useful in identifying tumor cells and are potential candidates for use in cancer therapy . Mechanism of tumor antigenesis Normal protein s in the body ... of tumor antigens Initially they were broadly classified into two categories based on their pattern of expression Tumor Specific Antigens TSA , which are present only on tumor cells and not on any other cell and Tumor Associated Antigens TAA , which are present on some tumor cells and also some normal cells. This classification, however,is imperfect because many antigens thought to be tumor specific turned out to be expressed on some normal cells as well. The modern classification of tumor ... needed date June 2010 Products of Mutated Oncogenes and Tumor Suppressor Genes Products of Other Mutated Genes Overexpressed or Aberrantly Expressed Cellular Proteins Tumor Antigens Produced ... Specific Differentiation Antigens Types Any protein produced in a tumor cell that has an abnormal structure due to mutation can act as a tumor antigen. Such abnormal proteins are produced due to mutation of the concerned gene . Mutation of protooncogene s and tumor suppressor s which lead to abnormal protein production are the cause of the tumor and thus such abnormal proteins are called tumor specific antigens . Examples of tumor specific antigens include the abnormal products of ras and p53 genes. In contrast, mutation of other genes unrelated to the tumor formation may lead to synthesis of abnormal proteins which are called tumor associated antigens . Proteins that are normally produced in very low quantities but whose production is dramatically increased in tumor cells, trigger an immune ... in melanoma cells. Oncofetal antigen s are another important class of tumor antigens. Examples are alphafetoprotein ... s may also have an abnormal structure in tumor cells and could thus be targets of the immune system ... more details
Glial tumor is a general term for numerous tumors of the central nervous system , including astrocytomas , ependymal tumor s, glioblastoma multiforme , and primitive neuroectodermal tumor s. External links http www.cancer.gov Templates db alpha.aspx?CdrID 45697 Glial tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Nervous system neoplasia oncology stub ... more details
Infobox Disease Name Neuroectodermal tumor Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D018358 A neuroectodermal tumor is a tumor of the central nervous system central or peripheral nervous system . See also Neuroendocrine tumors Neuroectoderm Primitive neuroectodermal tumor PNET Medulloblastoma External links http www.cancer.gov Templates db alpha.aspx?CdrID 45952 Neuroectodermal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Central nervous system tumors Category Anatomical pathology Category Nervous system neoplasia oncology stub ... more details
Micrograph of a neuroendocrine tumor. H&E stain . DiseasesDB ICD10 ICD9 ICD9 209 ICDO M8013 3 ... goblet cell cancer , a rare gastrointestinal tract tumor . ref name vanEeden2007 cite doi 10.1111 j.1365 2559.2007.02883.x ref Placing a given tumor into one of categories depends on well defined ... for pulmonary carcinoid tumor and small cell carcinoma journal Mod Pathol. volume 14 issue 9 pages ... Ramage2005 Within the broad category of neuroendocrine tumors there are many different tumor types ref ... a very small proportion of the tumors or cancers at these locations. Pituitary neuroendocrine tumor ... Parathyroid tumors Thymus and mediastinal carcinoid tumors ref name Soga1999 cite pmid 10550713 ref ... urinary tract carcinoid tumor and neuroendocrine carcinoma ref name Murali2006 cite pmid 17076534 ref ref name Mikuz1993 cite pmid 7511278 ref ovary neuroendocrine tumor of the cervix ref name Soga2001Cerv ... by the European Neuroendocrine Tumor Society. ref name Tan2011 Histopathology Image Small intestine ... tumor at bottom third of image, showing the typical intramural within the wall location, and overlying ... . Some neuroendocrine tumor cells possess especially strong hormone receptor biochemistry receptor ... and upper neck. ref Tebbi CK. Carcinoid Tumor. http emedicine.medscape.com article 986050 overview ... autopsy cases, ... incidence of tumor was 10 6 60 in individuals having histological studies of all .... ref name Pommier 10 ref name HC Health Communities. Carcinoid Tumor Overview. http www.healthcommunities.com ... Cushing s syndrome . Occasionally, haemorrhage or the effects of tumor bulk are the presenting symptoms ... ref name Pommier with an intense desmoplastic reaction at the tumor site, or of the mesentery ... or PNETs not to be confused with the Primitive neuroectodermal tumor primitive neuroectodermal PNET ... hormone related peptide tumor In these functional tumors, the frequency of malignancy and the survival ... facial tumor disease in Tasmanian Devil s. ref name Bostanci Bostanci A. Wildlife biology. A devil ... more details
An ependymal tumor is a type of brain tumor that begins in cells lining the spinal cord central canal fluid filled space down the center or the Ventricular system ventricles fluid filled spaces of the brain . Ependymal tumors may also form in the choroid plexus tissue in the ventricles that makes cerebrospinal fluid . Also called ependymoma . External links http www.cancer.gov Templates db alpha.aspx?CdrID 45679 Ependymal tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Central nervous system tumors Category Brain tumor oncology stub ... more details
Infobox disease Name Warthin s tumor ICD10 ICD10 D 11 d 10 ICD9 ICD9 210.2 ICDO 8561 0 Image Warthin s tumor.jpg Caption This Warthin s tumor presented as a parotid mass in a middle aged male, who underwent superficial parotidectomy. The tumor, at the right of the image, is well demarcated from the adjacent ... Warthin s tumor or Warthin tumour , also known as wiktionary Papillary papillary cystadenoma lymphomatosum or adenolymphoma, is a type of benign tumor of the salivary glands . Etiology Its etiology ... times greater risk of developing Warthin s tumor than the general population. ref name robbins ... than pleomorphic adenoma , Warthin s tumor is the second most common benign parotid tumor. Characteristic ... tumor arising from the parotid gland. Warthin s tumor primarily affects older individuals age 60&ndash ... been associated with a strong male predilection. This change is possibly due to the tumor s association with cigarette smoking and the growing use of cigarettes by women. The tumor is slow growing ... mandible . In 5&ndash 14 of cases, Warthin s tumor is bilateral, but the two masses usually are at different times. Warthin s tumor is highly unlikely to become malignant . Histology The appearance of this tumor under the microscope is unique. There are cystic spaces surrounded by two uniform rows ... removal . It is non recurrent . Additional images gallery Image Warthin tumor 1 .jpg Histopathology of Warthin tumor in the parotid gland. H&E stain. Image Warthin tumor 2 .jpg Histopathology of Warthin tumor in the parotid gland. Another view of a file Warthin tumor 1 .jpg . H&E stain. Image Warthin tumor 3 .jpg Histopathology of Warthin tumor in the parotid gland. Higher magnification of a file Warthin tumor 1 .jpg . H&E stain. Image Papillary cystadenoma lymphomatosum2.jpg Intermediate magnification micrograph of a Warthin tumor . Image Papillary cystadenoma lymphomatosum3.jpg High magnification micrograph of a Warthin tumor showing the characteristic bilayered epithelium. gallery See ... more details
Orphan date February 2009 A functioning tumor is a tumor that is found in endocrine tissue and makes hormones chemicals that travel in the bloodstream and control the actions of other cells or organs . External links http www.cancer.gov Templates db alpha.aspx?CdrID 458094 Functioning tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia oncology stub ... more details
A papillary tumor is a tumor shaped like a small mushroom , with its stem attached to the epithelial layer inner lining of an organ. External links http www.cancer.gov Templates db alpha.aspx?CdrID 46240 Papillary tumor entry in the public domain NCI Dictionary of Cancer Terms NCI cancer dict Category Types of neoplasia oncology stub ... more details
A Mixed tumor is a tumor that derives from multiple tissue types. ref http medical dictionary.thefreedictionary.com mixed tumor ref For example, a Chondroid syringoma is a cutaneous condition characterized histology histologically by nests of cuboidal or polygonal epithelial Cell biology cells in the dermis . ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 667 and it s of two types 1 derived from a single germ cell layer that differentiates into more than one cell type 2 derived from more than one germ cell layer totipotent cells See also Malignant mixed tumor Cylindroma Complex and mixed tumor List of cutaneous conditions References reflist Epidermal growth stub Category Epidermal nevi, neoplasms, cysts ... more details
Infobox Disease Name Adenomatoid tumor Image Adenomatoid tumour b very high mag.jpg Caption High magnification micrograph of an adenomatoid tumor. H&E stain . DiseasesDB ICD10 ICD9 ICDO 9054 0 OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D018254 Adenomatoid tumor is a benign mesothelial tumor . It generally presents in the genital tract, in regions such as the testis ref cite journal author Williams SB, Han M, Jones R, Andrawis R title Adenomatoid tumor of the testes journal Urology volume 63 issue 4 pages 779 81 year 2004 pmid 15072910 doi 10.1016 j.urology.2003.11.035 ref and epididymis . ref name titleAdenomatoid tumor of the epididymis cite web url http www.gfmer.ch selected images v2 detail list.php?cat1 6&cat3 139&stype d title Adenomatoid tumor of the epididymis accessdate 2007 12 15 format work ref However, it also has been found in the pancreas . ref name titleModern Pathology Adenomatoid Tumor of the Pancreas A Case Report with Comparison of Histology and Aspiration Cytology cite journal author Overstreet K, Wixom C, Shabaik A, Bouvet M, Herndier B title Adenomatoid tumor of the pancreas a case report with comparison of histology and aspiration cytology journal Mod Pathol. volume 16 issue 6 pages 613 7 year 2003 month Jun pmid 12808068 doi 10.1097 01.MP.0000072803.37527.C8 url http www.nature.com modpathol journal v16 n6 full 3880812a.html ref In the female, it has been found in the body of the uterus and the fallopian tube . ref cite journal author Huang CC, Chang DY, Chen CK, Chou YY, Huang SC title Adenomatoid tumor of the female genital tract journal Int J Gynaecol Obstet volume 50 issue 3 pages 275 80 year 1995 month Sep pmid 8543111 doi 10.1016 0020 7292 95 02453 J url http linkinghub.elsevier.com retrieve pii 002072929502453J ref References reflist Soft tissue tumors and sarcomas Category Benign neoplasms neoplasm stub ... more details
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