Infobox UK place official name Hinxton country England region East of England os grid reference TL496450 latitude 52.083 longitude 0.183 post town SAFFRON WALDEN postcode area CB postcode district CB10 dial code 01799 shire county Cambridgeshire constituency westminster South Cambridgeshire UK Parliament constituency South Cambridgeshire population 320 hide services Yes static image File Hinxton, SS John & Mary geograph.org.uk 2963.jpg 250px static image caption SS John & Mary Hinxton is a village in South Cambridgeshire , England . It is the home to the Wellcome Trust Genome Campus , which includes the Wellcome Trust Sanger Institute and the European Bioinformatics Institute . The 2001 population was 315. ref cite web url http www.cambridgeshire.gov.uk NR rdonlyres 4C7C20FE CC27 49B5 91D2 B12085093760 0 Hinxton.pdf title Hinxton publisher Census date 2001 ref The River Cam runs through the village ... has no station. Hinxton parish s southern boundaries form the border between Cambridgeshire and Essex ... . History The name Hinxton is a contraction of Hengestestun , the town of Hengest . ref cite ... Society date 1901 ref The village of Hinxton is listed in the Domesday Book of 1086 as Hestitona ...?compid 66725 title Parishes Hinxton, A History of the County of Cambridge and the Isle of Ely ... has been in the possession of Jesus College, Cambridge since 1558. ref name bh Hinxton Hall Hinxton .... ref name bh In 1992 the hall was taken over by the Wellcome Trust. Hinxton Mill Hinxton Mill ... hinxton watermill.shtml title Hinxton Watermill publisher CambridgePPF ref Hinxton Village Hall File ..., a place to meet and keep up with the news and share books. Generations of Hinxton residents have cared ... been in use as a public house since at least 1841, though there are records of an inn in Hinxton in 1744. ref name bh References Reflist External links Commons category inline Hinxton Category Villages in Cambridgeshire Category Civil parishes in Cambridgeshire fr Hinxton nl Hinxton pl Hinxton ... more details
Image EBI and Sanger Center, Genome campus, Cambridgeshire.jpg thumb European Bioinformatics Institute EBI and part of the Sanger Institute on the Genome Campus The Wellcome Trust Genome Campus is a scientific research campus built in the grounds of Hinxton Hall, located in the village of Hinxton , Cambridgeshire . It is owned by the Wellcome Trust , and its largest component is the Wellcome Trust Sanger Institute which employs around 900 people. It also is the site of the European Bioinformatics Institute EBI , the bioinformatics outstation of the European Molecular Biology Laboratory , which currently employs around 400 people. File hinxton hall.jpg thumb The site hosted the Medical Research Council UK MRC Rosalind Franklin Center for Genomics Research until its closure in 2005 . In addition to the research institutions, there are facilities on the campus dedicated to training and conferences these include the former Hinxton Hall buildings. coord 52 05 N 0 11 E region GB type city source GNS enwiki display title External links commonscat Genome campus http www.hinxton.wellcome.ac.uk Official Website http images.businessweek.com ss 06 12 1201 id awards source 8.htm BusinessWeek Architectural Record Awards page Wellcome Trust Category Cambridgeshire Category Wellcome Trust UK org stub biosci stub ... more details
Hanley Grange is the name given to an Eco towns UK eco town planned for land north of Hinxton in South Cambridgeshire . Initial proposals for 8,000 homes rising to 12,800 homes were published. The site proposed to be developed is on Grade 2 agricultural land, owned in part by a development company, Jarrow Investments, which works closely with supermarket giant Tesco . Local opposition through the Stop Hanley Grange Group of Parish Councils, is focussed on lack of infrastructure, overbuilding already in Cambridgeshire, and the proposal that the development of the eco town concept on such a scale is best dealt with through an alternative scheme at Northstowe , north of Cambridge. The petition launched against the Hanley Grange plan was signed by Top Gear current format Top Gear presenters Jeremy Clarkson , James May and Richard Hammond on 18 May 2008 at the Red Lion Pub at Hinxton, Cambs. On Wednesday 16 July 2008, a significant landowner, the Wellcome Trust announced it was not proceeding with the Hanley Grange eco town proposal. ref http www.wellcome.ac.uk News Media office Press releases 2008 WTX049860.htm ref On 24 July 2008, Tesco, through their agent Jarrow Investments, said they intend to continue with an application for an eco town on 264 hectares under their control. Revised plans provide for 6,500 houses. References Reflist added above External links Sources by script assisted edit External links http www.hanleygrange.co.uk Hanley Grange official website http www.stophanleygrange.org.uk Stop Hanley Grange Action Group http www.communities.gov.uk news corporate 904561 Communities and Local Government Eco town credentials coord 52.10 N 0.19 E type landmark region GB display title Category Towns in Cambridgeshire Category Eco towns ... more details
pf.html . The Hinxton Group met recently for the first time, in Cambridge , and published a consensus ... surrounding Hwang Woo Suk , the Hinxton Group has additionally recommended a number of measures ... from the United States National Academies http www.hinxtongroup.org The Hinxton Group An International ... more details
NCN Route 11 is a Sustrans National Cycle Route connecting Harlow in Essex to King s Lynn in Norfolk . Route Harlow to Cambridge Image National Cycle Route 11 at Great Shelford.jpg thumb NCR 11 near Great Shelford, showing a double helix and a small part of the BRCA2 gene. Harlow Bishop Stortford Hinxton Sawston Cambridge Intersects with NCR 51 in Cambridge. A section of path, about two kilometres long, from Great Shelford to Addenbrookes Hospital in Cambridge, is decorated with over 10,000 lines of four colours representing the nucleotide sequence of the BRCA2 gene. This gene, implicated in early onset breast cancer, was discovered in 1994 the discoverers included scientists from nearby Addenbrookes Hospital and The Sanger Centre, Hinxton. This section of path also includes and commemorates the 10,000th mile of the National Cycle Network. Cambridge to King s Lynn Cambridge Burwell, Cambridgeshire Burwell Wicken, Cambridgeshire Wicken Ely, Cambridgeshire Ely Downham Market Watlington, Norfolk Watlington King s Lynn Intersects with National Cycle Route 1 near King s Lynn Expand section date June 2008 Proposed development Wicken Fen Vision Spine Route main Wicken Fen Lodes Way Route 11 between Cambridge and Ely had a gap in the route, due to the difficulties of crossing the many waterways of the Cambridgeshire Fens. In 2011, the new bridge over Swaffham Bulbeck Lode, and surfacing of several sections of cycle path enables complete use of the route. This section of route 11 had been called the the Wicken Fen Vision Spine Route, but in 2011 was named the Lodes Way. The project involves the construction of 18 km of cycleway and of a number of bridges over the man made waterways known as Cambridgeshire Lodes lodes . ref name WFV2 cite web url http www.wicken.org.uk vision lodesway.htm title The Wicken Vision Spine Route publisher National Trust for Places of Historic Interest or Natural Beauty National Trust date accessdate 2011 12 30 ref The Lodes Way still has a fo ... more details
Infobox Institute name European Molecular Biology Laboratory image File EMBL logo.svg 240px established 1974 head label Director General head Iain Mattaj president faculty 95 staff budget endowment debt city flagicon DE Heidelberg br flagicon France Grenoble br flagicon DE Hamburg br flagicon UK Hinxton near Cambridge br flagicon Italy Monterotondo near Rome flagicon Australia Clayton in Melbourne state address website http www.embl.org www.embl.org The European Molecular Biology Laboratory EMBL is a molecular biology research institution supported by 20 European countries and Australia as associate member state. EMBL was created in 1974 and is an intergovernmental organisation funded by public research money from its member states. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of molecular biology. The Laboratory operates from five sites the main Laboratory in Heidelberg, and Outstations in Hinxton the European Bioinformatics Institute EBI , Grenoble, Hamburg, and Monterotondo near Rome. Research at EMBL Image EMBL Heidelberg.jpg 190px right thumbnail EMBL main entrance Each of the sites has a specific research field. The European Bioinformatics Institute EBI is a hub for bioinformatic research and services, developing and maintaining a large number of databases which are free of charge for the scientific community. At Grenoble and Hamburg, research is focused on structural biology. EMBL s dedicated Mouse Biology Unit is located in Monterotondo. At the headquarters in Heidelberg, there are units in Cell Biology and Biophysics, Developmental Biology, Genome Biology and Structural and Computational Biology as well as service groups complementing the aforementioned research fields. Many scientific breakthroughs have been made at EMBL, most notably the first systematic genetic analysis of embryonic development in the fruit fly by Christiane N sslein Volhard and Eric Wieschaus , for which they were awarded the Nobel Prize for ... more details
accessdate 2010 06 28 ref Wellcome Trust Genome Campus File Sanger Institute and Hinxton Hall, Cambridge ... moved into temporary laboratory space at Hinxton Hall ref name sanger1 in Cambridgeshire . This convert ... was the founding Director of the Sanger Institute. Sulston was instrumental in the choice of the Hinxton ... cited publisher Wellcome Trust accessdate 2009 01 22 ref Faculty File Hinxton hall.jpg thumb right ... Institute Hinxton International Cancer Genome Consortium The International Cancer Genome Consortium ... Hinxton Courses and Conferences http nobelprize.org nobel prizes medicine laureates 2002 ... more details
Multiple issues orphan February 2009 notability September 2011 self published September 2011 tense date September 2011 EMBRACE A European Model for Bioinformatics Research and Community Education is a project with the objective of drawing together a wide group of experts throughout European Union Europe who are involved in the use of information technology in the biomolecule biomolecular sciences. The EMBRACE Network of Excellence will optimise informatics and information exploitation by pure and applied biological scientists in both the academic and commercial sectors. ref cite web url http ec.europa.eu research health genomics newsletter issue4 article04 en.htm title EMBRACE European Model for Bioinformatics Research and Community Education work EU Genomics News, Newsletter no 4 July 2005 publisher Europa web portal EUROPA accessdate 2007 11 06 ref ref cite book last Rice first Peter M. coauthors Alan J. Bleasby, Syed A. Haider, Jon C. Ison, Shaun McGlinchey, Mahmut Uludag year 2006 month December title EMBRACE Bioinformatics Data and Analysis Tool Services for e Science journal Proceedings of the Second IEEE International Conference on e Science and Grid Computing pages 146 publisher IEEE location Amsterdam isbn 0 7695 2734 5 doi 10.1109 E SCIENCE.2006.261079 ref The EMBRACE network will work to integrate the major databases and software tools in bioinformatics , using existing methods and emerging Grid service technologies. The integration efforts will be driven by an expanding set of test problems representing key issues for bioinformatics service providers and end user biologists. As a result, groups throughout Europe will be able to use the EMBRACE service interfaces for their own local or proprietary data and tools. EMBRACE makes many ready to go bioinformatics web services freely available to the international research community. The project is run from the European Bioinformatics Institute EBI in Hinxton , England . Fred Marcus is its EU project coordinato ... more details
to Hinxton it hosted two databases, one for nucleotide sequences the EMBL Data Library, now known ... at Hinxton, and the UK Research Councils have also provided funds for EBI s facilities in Hinxton ... more details
Genome Campus at Hinxton , near Cambridge , UK. She is one of the world s leading researchers in structural ... Trust Genome Campus at Hinxton near Cambridge . She was an organiser of the Intelligent Systems ... more details
for the Scottish inventor James Nasmyth James Nasmith 1740 1808 was an English clergyman, academic and antiquary. Life The son of a carrier who came from Scotland, and plied between Norwich and London, he was born at Norwich late in 1740. He was sent by his father to Amsterdam for a year to complete his school education, and entered in 1760 Corpus Christi College, Cambridge , where he graduated B.A. 1764, M.A. 1767, and D.D. 1797. ref Venn NSMT760J Nasmith, James ref In 1765 he was elected to a fellowship in his college, he acted for some time as its sub tutor, and in 1771 he was the junior proctor of the university. Having been ordained in the English church, he served for some years as the minister of the sequestrated benefice of Hinxton , Cambridgeshire . He was nominated by his college in 1773 to the rectory of St Mary Abchurch with St Laurence Pountney , London, but before he could be instituted he exchanged for the rectory of Snailwell , Cambridgeshire. When the headship of his college became vacant in 1778 but he declined the offer of it, and was promoted by Bishop James Yorke bishop James Yorke in 1796 to the rectory of Leverington , in the Isle of Ely . As magistrate for Cambridgeshire and chairman for many years of the sessions at Cambridge and Ely, he studied the Poor Laws and other economic questions affecting his district. He was also for some time chaplain to John Hobart, 2nd Earl of Buckinghamshire . After a long illness he died at Leverington on 16 October 1808, aged 67, and was buried in the church, where his widow erected a monument to his memory on the north side of the chancel. He had married in 1774 Susanna, daughter of John Salmon, rector of Shelton, Norfolk , and sister of Benjamin Salmon, fellow of his college. She died at Norwich on 11 November 1814, aged 75, bequeathing sums to charity. Works Nasmith devoted his leisure to antiquarian research, and he was elected Fellow of the Society of Antiquaries on 30 November 1769. He was occupied in a ... more details
George Hardinge 1743 1816 was an English judge, writer and Member of Parliament. Life He was born on 22 June new style 1743 at Canbury, a manorhouse in Kingston upon Thames . He was the third but eldest surviving son of Nicholas Hardinge , by his wife Jane, daughter of John Pratt judge Sir John Pratt . He was educated by Woodeson, a Kingston schoolmaster, and at Eton College under Edward Barnard provost Edward Barnard . Hardinge succeeded to his father s estate on the death of the latter on 9 April 1758. On 14 January 1761 he was admitted pensioner at Trinity College, Cambridge . He took no B.A. degree, but in 1769 obtained that of M.A. by royal mandate. ref Venn HRDN761G Hardinge, George ref On 9 June 1769 he was called to the bar Middle Temple , and soon had considerable practice at nisi prius. One of his friends at this time was Mark Akenside the poet. In 1776 he visited France and Switzerland. On 20 October 1777 he married Lucy, daughter and heiress of Richard Long of Hinxton, Cambridgeshire, who survived her husband. They had no children, but Hardinge educated and adopted as his son and heir George Nicholas Hardinge , son of his brother, Henry Hardinge. Soon after his marriage Hardinge went to live at Ragman s Castle, a small house at Twickenham . Here he saw much of his neighbour, Horace Walpole , and later wrote about him. In April 1782 he was appointed solicitor general to the Queen, and in March 1794 her attorney general. In 1783 he was counsel in the House of Commons for the defence of Sir Thomas Rumbold, 1st Baronet , and on 16 December of that year was counsel at the bar of the House of Lords for the East India Company , in opposition to Charles James Fox s India Bill. In 1784 he was returned M.P. for Old Sarum UK Parliament constituency Old Sarum , by the favour of his intimate friend, Thomas Pitt, 1st Baron Camelford . He was re chosen in November 1787, in 1790, 1796, and 1801. John Nichols printer John Nichols says he was an eloquent and ingenious spe ... more details
Infobox company name FlexGen B.V. logo File Logo FlexGen normal.jpg 250px type genre foundation 2004 founder location city Leiden location country The Netherlands location locations area served Worldwide key people industry Biotechnology products FlexArrayer, FleXelect custom oligopools services Custom oligopool synthesis revenue operating income net income owner num employees parent divisions subsid slogan FAST FLEXIBLE FOCUSED homepage http www.flexgen.nl footnotes intl FlexGen is a biotech company based in Leiden, the Netherlands. FlexGen is a spin off from Leiden University Medical Centre and Dutch Space part of EADS and has proprietary technologies for laser based in situ synthesis of oligonucleotides and other biomolecules. Products FleXelect http flexgen.nl index.php?cat products&page flexelect FleXelect sup TM sup oligopools consist of custom oligonucleotides in solution and can be used for in solution target enrichment prior to next generation DNA sequencing .Target enrichment or In solution hybrid selection is a method for genomic selection in an increasing amount of applications ref Lira Mamanova et. al., Target enrichment strategies for next generation sequencing, Nature journal Nature methods 2010 Feb 7 2 111 8.The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK. ref ref Tewhey R, Nakano M, Wang X, Pab n Pe a C, Novak B, Giuffre A, Lin E, Happe S, Roberts DN, LeProust EM, Topol EJ, Harismendy O, Frazer KA. Enrichment of sequencing targets from the human genome by solution hybridization. Genome Biol. 2009 10 10 R116. Epub 2009 Oct 16. PMID 19835619 PMC 2784331 ref such as Analysis of custom genomic regions of interest e.g. specific genes, multiple variants and or complete pathways . Analysis of Chromosomal translocation Validation of Single nucleotide polymorphism or SNPs typically after whole genome or whole exome studies Other research and diagnostic applications e.g. Synthetic biology An example of a recent applic ... more details
infobox biodatabase logo Image chembl logo.png description Biological database scope Molecules with drug like properties and biological activity organism center European Molecular Biology Laboratory laboratory flagicon UK European Bioinformatics Institute author John Overington, Team Leader released 2009 standard format url https www.ebi.ac.uk chembldb ChEMBL pmid PMID 21936816 download https www.ebi.ac.uk chembldb index.php downloads Downloads webservice sql sparql http rdf.farmbio.uu.se chembl snorql SNORQL webapp standalone license The ChEMBL data is made available on a Creative Commons Attribution Share Alike 3.0 Unported License versioning Chembl 12 frequency curation ChEMBL or ChEMBLdb is a manually curated chemical database of bioactive molecules with drug like properties. ref name Gaulton Cite journal last Gaulton first A coauthors et al. title ChEMBL a large scale bioactivity database for drug discovery journal Nucleic Acids Research volume issue pages year 2011 url issn doi 10.1093 nar gkr777 accessdate 2010 11 15 ref It is maintained by the European Bioinformatics Institute EBI , based on the Wellcome Trust Genome Campus , Hinxton, UK. The database, originally known as StARlite, was developed by a biotechnology company, Inpharmatica Ltd. latterly acquired by Galapagos NV . The data was acquired for EMBL in 2008 with an award from The Wellcome Trust , resulting in the creation of the ChEMBL chemogenomics group at EBI, led by John Overington. ref name Bender Cite journal last Bender first A coauthors title Databases Compound bioactivities go public journal Nature Chemical Biology volume 309 issue 6 pages year 2010 url http www.nature.com nchembio journal v6 n5 full nchembio.354.html issn doi 10.1038 nchembio.354 accessdate 2010 11 15 ref ref name pmid19194660 cite journal author Overington J title ChEMBL. An interview with John Overington, team leader, chemogenomics at the European Bioinformatics Institute Outstation of the European Molecular Biology Labora ... more details
The use of water power in Britain was at its peak just before the Industrial Revolution . The need for power was great and steam power had not yet become established. It is estimated that at this time there were well in excess of ten thousand water mill watermills in the country. Most of these were wheat corn mills to grind flour , but almost any industrial process needing motive power, beyond that available from the muscles of men or animals, used a water wheel , unless a wind mill was preferred. Today only a fraction of these mills survive. Many are used as private residences, or have been converted into offices or flats. A small number have been preserved or restored as museums where the public can see the mill in operation. This is a list of some of the surviving and demolished watermill s and tide mill s in the United Kingdom . Image Kingsbury Water Mill 20031012 007.jpg thumb Kingsbury Watermill Museum, St Albans England Berkshire Abbey Mill, Reading Abbey Mill , Reading, Berkshire Reading Calcot Mill , Reading, Berkshire Reading Buckinghamshire Ford End Mill , Ivinghoe Hambleden Mill , Mill End Pann Mill , High Wycombe Cambridgeshire Hinxton Mill , Hinxton Houghton Mill , Houghton, Cambridgeshire Houghton Lode Watermill , Lode, Cambridgeshire Lode Sacrewell Mill , Peterborough, Cambridgeshire Soham Mill , Soham Cheshire Bunbury Mill , Bunbury, Cheshire Bunbury Dunham Massey Sawmill , Altrincham Nether Alderley Mill , Macclesfield Quarry Bank Mill , Styal Stretton Watermill , Stretton, Chester Stretton Trafford Mill , Mickle Trafford , Chester Cumbria Acorn Bank Garden & Watermill Acorn Bank Mill , Penrith, Cumbria Penrith Boot Watermill , Eskdale, Cumbria Eskdale http www.eskdalemill.co.uk Official Website Gleaston Watermill , Ulverston http www.watermill.co.uk Official Website Heron Corn Mill , Milnthorpe http heronmill.org Official Website Little Salkeld Watermill , Penrith, Cumbria Penrith http www.organicmill.co.uk Official Website Stott Park Bobbin Mill ... more details
Ruth R. Faden, M.P.H., Ph.D. , is the Philip Franklin Wagley Professor of Biomedical Ethics and Executive Director of The Johns Hopkins Berman Institute of Bioethics at Johns Hopkins University . She is also a Senior Research Scholar at the Kennedy Institute of Ethics, Georgetown University . She has served on several national advisory committees and commissions. She chaired the President s Advisory Committee on Human Radiation Experiments established by Former President Bill Clinton in 1994. Dr. Faden is a notable commentator on bioethics in several media outlets as well a guest speaker at numerous conferences. She is a recipient of the Golden Apple Award at the Johns Hopkins School of Public Health . She holds a B.A from the University of Pennsylvania , a M.A. in General Studies in Humanities from the University of Chicago and a M.P.H. and Ph.D. Program in Attitudes and Behavior from the University of California, Berkeley . Academic work Dr. Faden is the author and editor of numerous books and articles on biomedical ethics, health policy, clinical ethics, and moral philosophy. Some of her notable works including A History and Theory of Informed Consent with Tom L. Beauchamp , AIDS, Women and the Next Generation Ruth Faden, Gail Gellerand Madison Powers, eds. , HIV, AIDS and Childbearing Public Policy, Private Lives Ruth Faden and Nancy Kass, eds. She a frequent commentator on media outlets such as The New York Times and The Baltimore Sun. Her current research interests include bioethics and public policy ethics and cellular engineering neuroethics ethics and bioterrorism genetics and public policy and justice. She is a fellow of the American Psychological Association , The Hastings Center and a member of The Institute of medicine. She is working on the following research projects Bellagio Meeting on Pandemic Influenza ref http www.bioethicsinstitute.org web page 905 sectionid 377 pagelevel 3 interior.asp ref Hinxton Group ref http www.hinxtongroup.org ref Stem Cel ... more details
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