CytochromeC1 is formed in the cytosol and protein targeting targeted to the mitochondrial intermembrane space. It is one of the constituents of Coenzyme Q cytochrome c reductase complex III , which forms the third proton pump in the mitochondrial electron transport chain . Cytochrome c sub 1 sub is a subunit of the electron transport chain protein ubiquinol cytochrome c reductase Ubiquinol Cytochrome c Reductase UQCR, Complex III or Cytochrome bc1 complex , which consists of the products of one mitochondrially encoded gene, MT CYB MTCYTB mitochondrial cytochrome b and ten nuclear genes UQCRC1 , UQCRC2 , Cytochromec1, UQCRFS1 Rieske protein , UQCRB , UQCRQ http www.ncbi.nlm.nih.gov nuccore 98986462 11kDa protein , UQCRH cyt c1 Hinge protein , Rieske Protein presequence, cyt. c1 associated protein , and UQCR http www.ncbi.nlm.nih.gov nucleotide 19923785 Rieske associated protein . External links MeshName Cytochromec1 Category Peripheral membrane proteins membrane protein stub ... more details
Image Cytochrome c.png thumb 250px Cytochrome c with heme c . Cytochromes are, in general, membrane bound hemoprotein s that contain heme groups and carry out electron transport . They are found either as Protein subunit monomeric protein s e.g., cytochrome c or as Protein subunit subunits of bigger enzymatic complexes that catalyze redox reactions. They are found in the mitochondrion mitochondrial inner membrane and endoplasmic reticulum of eukaryote s, in the chloroplast s of plants, in photosynthesis photosynthetic microorganism s, and in bacteria . History Cytochromes were initially described in 1884 by MacMunn as respiratory pigments myohematin or histohematin . ref name MacMunn cite journal ... pyridine ligated state, i.e., the pyridine hemochrome method. Within each class, cytochrome a , b , or c ... across the membrane, and assembly of flagellum flagella . Types Several kinds of cytochrome exist and can ... potential. Three types of cytochrome are distinguished by their prosthetic groups class wikitable Type prosthetic group Cytochrome a heme a Cytochrome b heme b Cytochrome d tetrapyrrolic chelate of iron ref MeshName Cytochrome d ref The definition of cytochrome c is not defined in terms of the heme group. ref MeshName Cytochrome c Group . ref There is no cytochrome e, but there is a cytochrome f , which is often considered a type of cytochrome c. ref eMedicineDictionary Cytochrome ... a and a sub 3 sub Cytochrome c oxidase Complex IV with electrons delivered to complex by soluble cytochrome c hence the name b and CytochromeC1 c sub 1 sub Coenzyme Q cytochrome c reductase Complex III b sub 6 sub and Cytochrome f f Plastoquinol plastocyanin reductase A completely distinct family of cytochromes is known as the cytochrome P450 oxidase s, so named for the characteristic Soret ... Category Cytochromes cs Cytochrom de Cytochrome es Citocromo eo Citokromo eu Zitokromo fr Cytochrome id Sitokrom it Citocromi he mk ja pl Cytochromy pt Citocromo ru ... more details
Letter NumberCombination C0 C2 B1 D1 wiktionary C1 , C01 , C.I or C 1 may refer to Diverse C1, an international ... normally introduced at the start of a parliamentary session in the Canadian House of Commons C1, also ... differentiable functions C1, a note octave in music C1, a level in the Common European Framework of Reference for Languages C1, the code for permission to use specific land or premises for hotels, in town and country planning in the United Kingdom C1, the first of four pure modules taken in the Advanced Level UK Maths syllabus C1, a NRS social grade in the United Kingdom for the lower middle class ... station classes FM class of FM radio broadcasting in North America C1 pylon , a type of high voltage pylon C1 Television , a Mongolian Television Channel Schecter C 1 Hellraiser FR , a guitar model Caldwell 1 NGC 188 , an open cluster in Cepheus Biology C1 domain , an important secondary messenger protein domain C1 inhibitor , a human serine protease inhibitor C1 regulatory sequence for the insulin gene Apolipoprotein C1 , a human lipoprotein CytochromeC1 , a precursor protein to Cytochrome C Proanthocyanidin C1 , a type of polyphenolic compound Prostaglandin C1 , a form of prostaglandins C1 & P1 Neuroscience , a component of the visual evoked potential ATC code C01 , a subgroup of the Anatomical ... C0 and C1 control codes defined in ISO 6429 C1 protocol , a 1984 protocol for file transfer, also known as Punter C One , a single board microcomputer Counter Strike C1 , a slang expression from the video game, used to express agreement TCSEC C1 security class C1 NES TV , a family of Nintendo television set hybrids manufactured by Sharp Corporation in 1983 ATI C1, codename of the Xbox 360 ... locomotives class BMW C1 , a security scooter with a roof Chevrolet Corvette C1 , any model corvette ... Circumferential Road 1, a highway in the Philippines Citro n C1 , a small car DFW C.I , a WWI ... Ford C1 platform , the Ford Motor Company s global compact car automobile platform Friedrichshafen C.I ... more details
AJ, Millett F title Electrostatic interaction of cytochrome c with cytochromec1 and cytochrome ...PBB geneid 54205 The Cytochrome complex , or cyt c is a small heme protein found loosely associated with the inner membrane of the mitochondrion . It belongs to the cytochrome c family of proteins. Cytochrome c is a highly soluble protein, unlike other cytochrome s, with a solubility of about 100 g L ... between Coenzyme Q cytochrome c reductase Complexes III and cytochrome c oxidase IV . In humans, cytochrome c is encoded by the CYCS gene . ref name entrez cite web title Entrez Gene cytochrome ... T, Russo MA, Farber JL title Cytochrome c release upon Fas receptor activation depends on translocation ... jbc.M111350200 url issn ref Function Cytochrome c is a component of the electron transport chain in mitochondria. The heme group of cytochrome c accepts electrons from the b c1 complex and transfers electrons to the cytochrome oxidase complex. Cytochrome c is also involved in initiation of apoptosis . Upon release of cytochrome c to the cytoplasm, the protein binds apoptotic protease activating factor. ref name entrez Cytochrome c can catalyze several reactions such as hydroxylation and aromatic .... Species distribution Cytochrome c is a highly conserved protein across the spectrum of species ... in cytochrome c proteins from different species , adapted from Strahler, Arthur Science and Earth History, 1997. page 348. ref The cytochrome c molecule has been studied for the glimpse it gives ... PA79&dq chimpanzee rhesus cytochrome c&source web&ots wbEgDLqBGU&sig cyVtTiTyAjuMSEIfDzgWjaJCz M&hl ... also share identical cytochrome c molecules. ref name indiana Classes In 1991 R. P. Ambler recognized four classes of cytochrome c ref name pmid1646017 cite journal author Ambler RP title Sequence variability ... soluble cytochrome c of mitochondria and bacteria. It has the heme attachment site towards the N .... Class II includes the highspin cytochrome c . It has the heme attachment site closed to the N terminus ... more details
Orphan date February 2009 The Cytochrome b 245 protein complex is composed of cytochrome b alpha Cytochrome b 245, alpha polypeptide CYBA ref cite web title Entrez Gene CYBA cytochrome b 245, alpha polypeptide url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 1535 accessdate ref and beta CYBB ref cite web title Entrez Gene CYBB cytochrome b 245, beta polypeptide chronic granulomatous disease url http www.ncbi.nlm.nih.gov sites entrez?Db gene&Cmd ShowDetailView&TermToSearch 1536 accessdate ref chain. Gene expression NOV 002 treatment leads to gene expression changes in SKOV3 cells br CYBA 2.1 fold Cytochrome b 245 ref NOV 002 suppresses tumor cell growth by modulating redox sensitive cell signaling Robert Bowers, Danyelle M. Townsend Christopher J. Pazoles and Kenneth D. Tew Depts. Biomedical and Pharmaceutical Sciences Cell and Molecular Pharmacology and Experimental Therapeutics, Medical University of South Carolina 173 Ashley Ave., Charleston, SC 29425 Novelos Therapeutics, Inc., One Gateway Ctr, Newton, MA 024584 ref alpha polypeptide p22 PHOX br 22 KD subunit of NADPH oxidase br produces superoxide anion br References reflist Category Cytochromes protein stub ... more details
morefootnotes date September 2010 Cytochrome f is the largest subunit of cytochrome b6f complex cytochrome b sub 6 sub f complex plastoquinol&mdash plastocyanin reductase EC number 1.10.99.1 . The crystal structures of soluble lumen side domain of cytochrome f reveal two structural domains a small one above a larger one, which, in turn, is on top of the attachment to the membrane domain. The large domain consists of an antiparallel sandwich and a short heme binding peptide , which form a three layer structure. The small domain is inserted between two strands of the large domain and is an all domain. The heme is bound between two short helices at the N terminus of cytochrome f . Within the second helix is the sequence motif for the c type cytochromes, Cys Xaa Xaa Cys His, which is covalently attached to the heme through thioether bonds of the two cysteine Residue chemistry residue s. The fifth heme iron ligand is histidine and the sixth heme iron ligand is the amino group of N terminal tyrosine residue Tyr 1 . Cytochrome f has an internal network of water molecules. It has been hypothesized that this water chain functions as a proton wire. The water chain appears to be a conserved ... of cytochrome f journal Photosynth. Res. year 2004 volume 80 pages 265 276 pmid 16328825 doi 10.1023 ... aspects of the cytochrome b sub 6 sub f complex structure of the lumen side domain of cytochrome f ... The heme redox center of chloroplast cytochrome f is linked to a buried five water chain journal ... cite journal author Prince, R.C. and George, G.N. title Cytochrome f revealed journal Trends ... issue 6 External links PDB 1CTM X ray structure of lumen side domain of cytochrome f from turnip Brassica rapa PDB 1CFM X ray structure of lumen side domain of cytochrome f from Chlamydomonas reinhardtii PDB 1CI3 X ray tructure of soluble domain of cytochrome f from cyanobacterium Phormidium laminosum InterPro IPR002325 InterPro entry for cytochrome f MeshName Cytochrome f Category Photosynthesis ... more details
cytochrome bc1 complex Pfam PF00033 InterPro IPR005797 SMART PROSITE PDOC00171 SCOP 3bcc ... 9 210 Cytochrome b b6 is the main subunit of transmembrane cytochrome bc1 complex cytochrome bc1 and Cytochrome ... conservation of protein regions in the protonmotive cytochrome b and their possible roles in redox ... S, Crimi M, Ghelli A, Patarnello T, Meyer A title Mitochondrial cytochrome b evolution and structure ... and in aerobic prokaryotes, cytochrome b is a component of respiratory chain complex III EC number 1.10.2.2 also known as the bc1 complex or ubiquinol cytochrome c reductase. In plant chloroplasts and cyanobacteria, there is an analogous protein, cytochrome b6, a component of the plastoquinone ... role in the cell. Structure Cytochrome b b6 ref name PUB00003404 cite journal author Howell N title Evolutionary conservation of protein regions in the protonmotive cytochrome b and their possible ... T, Meyer A, De Vries S title Mitochondrial cytochrome b evolution and structure of the protein ... that probably has 8 transmembrane segments. In plants and cyanobacteria, cytochrome b6 consists of two subunits encoded by the petB and petD genes. Cytochrome b b6 non covalently binds two heme ... atoms of these two heme groups. Use in phylogenetics Cytochrome b is commonly used to determine ... studies involving cytochrome b have resulted in new classification schemes and have been ... relationships. ref name 2001Castresana cite journal last1 Castresana first1 J. title Cytochrome b ... 4 ref Clinical significance Mutations in cytochrome b primarily result in exercise intolerance in human ..., Jackson MJ, Turnbull DM, Taylor RW title A mitochondrial cytochrome b mutation causing severe respiratory ... mutations in cytochrome b of Plasdmodium falciparum and P. berghei are associated with resistance to the anti ... in the quinone binding domain 2 Qo 2 of the cytochrome b gene journal Parasitology International ... url issn ref Human genes Human genes encoding cytochrome b proteins include CYB5A cytochrome b5 ... more details
Orphan date September 2008 Pfam box Symbol Cytochrom B561 Name Cytochrome b561 image width caption Pfam PF03188 InterPro IPR004877 SMART Prosite SCOP TCDB 5.A.4 OPM family OPM protein PDB Cytochrome b561 is a secretory vesicle specific integral membrane protein responsible for electron transport , binding two heme groups non covalently. Human proteins containing this domain CYB561 CYB561D1 CYB561D2 CYBASC3 CYBRD1 Category Protein domains Category Protein families Category Integral membrane proteins membrane protein stub ... more details
protein Name Cytochrome b5 caption Rat cytochrome b5 bound to heme image 1jex cyto b5.png width HGNCid 2570 Symbol CYB5A AltSymbols CYB5 EntrezGene 1528 OMIM 250790 RefSeq NM 001914 UniProt P00167 PDB 1JEX ECnumber Chromosome 18 Arm q Band 23 LocusSupplementaryData Pfam box Symbol Cyt B5 Name Cytochrome b5 Pfam PF00173 InterPro IPR001199 PROSITE PDOC00170 PDB PDB2 1aqa , PDB2 1aw3 , PDB2 1awp , PDB2 ... are water soluble. The family of cytochrome b sub 5 sub like proteins includes besides cytochrome b ... cytochrome b sub 2 sub small L small lactate dehydrogenase EC number 1.1.2.3 , sulfite oxidase EC ... 1.7.1.3 , and plant and fungal cytochrome b sub 5 sub acyl lipid desaturase fusion proteins. Structure 3 D structures of a number of cytochrome b sub 5 sub and yeast flavocytochrome b sub 2 sub are known ... crevice. Two isomers of cytochrome b sub 5 sub , referred to as the A major and B minor forms, differ by a 180 rotation of the heme about an axis defined by the and meso carbons. Cytochrome b sub 5 sub in some biochemical reactions EC number 1.6.2.2 cytochrome b5 reductase cytochrome b sub 5 sub ... EC number 1.10.2.1 small L small L ascorbate cytochrome b5 reductase ascorbate&mdash cytochrome b sub ... 2 sub O See also P450 containing systems Cytochrome b5, type A References cite journal author Lederer, F. title The cytochrome b sub 5 sub fold an adaptable module journal Biochimie year 1994 volume 76 ..., J.A., Michaelson, L.V. and Sayanova, O. title The role of cytochrome b sub 5 sub fusion desaturases ... studies of the rat outer mitochondrial membrane cytochrome b sub 5 sub journal Biochemistry year 1992 ... Schenkman, J.B. and Jansson, I. title The many roles of cytochrome b sub 5 sub journal Pharmacol ... 2 External links PDB 1B5A Solution structure of rat cytochrome b sub 5 sub form A PDB 1B5B Solution structure of rat cytochrome b sub 5 sub form B PDB 1CXY X ray structure of cytochrome b sub 558 sub from Ectothiorhodospira vacuolata OMIM 250790 Methemoglobinemia due to deficiency of cytochrome b ... more details
Pfam box Symbol Cytochrom B559 Name Cytochrome b559, alpha gene psbE and beta gene psbF subunits image PDB 2axt EBI.jpg width caption Structure of Photosystem II from Thermosynechococcus elongatus . ref name pmid16355230 cite journal author Loll B, Kern J, Saenger W, Zouni A, Biesiadka J title Towards complete cofactor arrangement in the 3.0 A resolution structure of photosystem II journal Nature volume 438 issue 7070 pages 1040 4 year 2005 month December pmid 16355230 doi 10.1038 nature04224 url ref Pfam PF00283 InterPro IPR013081 SMART PROSITE PDOC00464 SCOP TCDB OPM family 2 OPM protein 2axt PDB PDB2 1izl , PDB2 1w5c , PDB2 2axt Pfam box Symbol Cytochrom B559a Name Lumenal portion of Cytochrome b559, alpha gene psbE subunit image PDB 1izl EBI.jpg width caption Structure of oxygen evolving photosystem II from Thermosynechococcus vulcanus . ref name pmid12518057 cite journal author Kamiya N, Shen JR title Crystal structure of oxygen evolving photosystem II from Thermosynechococcus vulcanus at 3.7 A resolution journal Proc. Natl. Acad. Sci. U.S.A. volume 100 issue 1 pages 98 103 year ... , PDB2 2axt Cytochrome b559 is an important component of Photosystem II . PSII is a multisubunit protein ... issue 2 3 pages 75 96 year 2004 pmid 14871485 doi 10.1016 j.bbabio.2003.12.004 ref . Cytochrome b559 ... the haem. Although cytochrome b559 is a redox active protein, it is unlikely to be involved in the primary .... Instead, cytochrome b559 could participate in a secondary electron transport pathway that helps protect PSII from photo damage. Cytochrome b559 is essential for PSII assembly ref name PUB00015364 ... studies of the non heme iron and cytochrome b559 in a Chlamydomonas reinhardtii PSI mutant ... and beta subunits of cytochrome B559. In the alpha sbunit it occurs together with a lumenal domain InterPro IPR013082 , while in the beta subunit it occurs on its own. Cytochrome b559 can exist ... journal author Mizusawa N, Yamashita T, Miyao M title Restoration of the high potential form of cytochrome ... more details
Pfam box Symbol p450 Name Cytochrome P450 image CytP450Oxidase 1OG2.png width caption Cytochrome P450 ... , PDB2 5cpp , PDB2 6cp4 , PDB2 6cpp , PDB2 7cpp , PDB2 8cpp The cytochrome P450 superfamily officially ... of Cytochrome P450 Proteins Metal Ions in Life Sciences edition language publisher Wiley location New ... cite journal author Danielson PB title The cytochrome P450 superfamily biochemistry, evolution ... title Cytochrome P450 Homepage author Nelson D authorlink coauthors date work publisher ... Cytochrome P450 Homepage and allele names http www.cypalleles.ki.se CYP Allele Nomenclature Committee ... The active site of cytochrome P450 contains a heme iron center. The iron is tethered to the P450 protein ... S title Mechanism of oxidation reactions catalyzed by cytochrome p450 enzymes journal Chem. Rev. volume ... cite journal author Poulos TL, Finzel BC, Howard AJ title High resolution crystal structure of cytochrome .... Paul R. Ortiz de Montellano authorlink editor others title Cytochrome P450 structure, mechanism, and biochemistry ... state of the active site favors the transfer of an electron from NAD P H via cytochrome P450 reductase ... GG, Schenkman JB title Spin state control of the hepatic cytochrome P450 redox potential journal ... is transferred via the electron transport system, from either cytochrome P450 reductase , ferredoxin s, or cytochrome b5 , reducing the dioxygen adduct to a negatively charged peroxo group. This is a short ... CYPs involve the reduction of cytochrome P450 reductase variously CPR, POR, or CYPOR by NADPH , and the transfer of reducing power as electrons to the CYP. Cytochrome b5 cyb5 can also contribute reducing power to this system after being reduced by cytochrome b5 reductase CYB5R . FR Fd P450 ... both electrons required by the CYP come from cytochrome b5 . FMN Fd P450 systems originally found ... of these characteristics account for their central importance in medicine . Cytochrome P450 enzymes ... metabolism. Cytochrome P450 enzymes also function to metabolize potentially toxic compounds, including ... more details
Infobox TV channel name C1 Television C1 logofile C1 Television logo.png logosize 130px logoalt launch 2006 closed date share share as of share source owner slogan country flagcountry Mongolia broadcast area Ulaanbaatar headquarters Ulaanbaatar , Mongolia former names replaced names sister names timeshift names web http www.c1.mn www.c1.mn C1 Television lang mn 1 , or C1 , is a television broadcaster in Mongolia . History C1 was founded in June 2005. According to the station, it is the first in Mongolia to use fully digital video processing. TV Programming C1 Television broadcasts a variety of programming. The following are noteworthy News. C1 gets its foreign news clips from Reuters , and its domestic news from its own crew. Sport. C1 gets its sport news from the ESPN and Eurosport . It is also noteworthy that it broadcasted the UEFA Champions League 2006 2007 , and the 2006 FIFA World Cup live. C1 became the only Mongolian official broadcaster of FIFA World Cup 2010 in South Africa and aired all the matches live. The broadcasting was sponsored by several prominent local corporations that include Khan bank and Skytel among others.It is now broadcasting 2010 2011 UEFA Champions League Entertainment. C1 broadcasts Mongolian Cinema Mongolian Movies , Talk show s, and Movie News. Also C1 broadcasts Bizarre Foods with Andrew Zimmern , Ben 10 and Skins TV series . See also Media of Mongolia Communications in Mongolia External links http www.c1tv.mn Official Site mn icon This site isn t working at the moment Television in Mongolia Category Television in Mongolia Asia tv stub Mongolia stub ... more details
Infobox Motorcycle name BMW C1 image Image BMW C1 FF 200 frontale .jpg 220px BMW C1 Family Friend model alt Black and yellow BMW C1 scooter parked in front of a lake with boats and an amphibian aircraft ... predecessor successor class Scooter motorcycle Scooter The BMW C1 is an enclosed Scooter motorcycle ... 4 BMW C1.JPG thumb right thumb From left to right C1 200 Executive , C1 200 Family Friend , C1 125 base, C1 125 Executive alt Four BMW C1 scooters parked side by side in front of a lake, with mountains ... is acquired. The C1 weighed approximately convert 185 kg lb abbr on with a 40 60 weight distribution towards the back. History Image BMW C1 laterale .jpg thumb right C1 Family Friend with storage box alt A picture from the side through the cockpit areas of several BMW C1 scooters which are parked side by side in perfect alignment Image C1executive1.JPG thumb right upright alt C1 Executive alt Black BMW C1 scooter parked on a pedestrian area in a city street BMW s intention with the C1 was to appeal ... or motorbike but without many of the associated dangers or hassles. The C1 s most innovative design ... c1.htm title BMW C1 A Concept takes Shape work BMW World accessdate 2007 07 13 ref BMW tried ..., the C1 offered a standard of accident protection comparable to a European compact car. That was the prime marketing strategy to convert car buyers the C1 was claimed to be so safe that the rider ... to the helmet law for the C1. However, poor C1 sales in the United Kingdom may in part be attributable to the British government s refusal of BMW s request to change helmet regulations for C1 riders. ref name Telegraph2 Another country that requires C1 riders to wear a helmet is Sweden, although ..., BMW only sold 2,000 units in 2002, and ceased production of the C1 in October 2002. It was never made available in the USA. C1 E electric version In 2009 BMW used the same layout for the C1 E , an electric ... eSUM European Safer Urban Motorcycling . ref cite web url http www.gizmag.com bmw c1 e concept ... more details
Infobox Automobile image Image Citroen C1 front 20080417.jpg 250px Citro n C1 boxcolor name Citro n C1 ... Donato Coco The Citro n C1 is a city car produced by the France French manufacturer Citro n since 2005. The C1 was developed as part of the B Zero project by PSA Peugeot Citro n in a joint venture with Toyota . The Peugeot 107 is identical to the C1 other than the front bumper and front and rear ... convert 3.40 m in 1 in length. The body was designed by Donato Coco . Image Citroen C1 rear 20070511.jpg thumb left Rear view of 5 door Citro n C1 showing tail light clusters A notable feature of the 5 door C1 and 107, though not the Aygo, is the large tail light cluster, which extends from the edge of the rear doors to the rear window, meaning there is no external metal pillar car C pillar . The C1 ..., Der Spiegel , the C1 is the production car with the second best fuel economy both among petrol engines ... Citro n announced that it is recalling under 100,000 units of the C1 and the Peugeot 107, following ... File Citro n C1 front.JPG thumb right 2009 Citro n C1 facelift In January 2009, the C1 was facelifted at the same time as the Peugeot 107 and Toyota Aygo. The New C1 features a new front bumper incorporating ... up. Additional versions Designer Franco Sbarro created an extreme C1, called the C1 GT , a design ... car based on the C1, called the Citro n C1 ev ie since 30 April 2009. Its list price on that date ... title Electric Citro n C1 car is ready, but government grants are not url http business.timesonline.co.uk ... C1 Ev 27ie 30kw 239834 ref ref cite title The Electric Car Corporation Launches the Citro n C1 ev ... statistics reported by the ADAC German Automobile Club in May 2010 placed the Citro n C1 which ... links Commons category Citro n C1 http www.tpca cz.com en Link to Toyota Peugeot Citro n Automobile http www.citroenet.org.uk passenger cars psa c1c1 02.html C1 at Citroenet http crash.citroen1.info C1 Crash Test http world.citroen1.info C1 links Citro n World http www.autoexpress.co.uk carreviews ... more details
Pfam box Symbol C1 Name Phorbol esters diacylglycerol binding domain C1 domain image 1ptr.png width 200 caption C1 domain of PKC delta 1ptr small Middle plane of the lipid bilayer black dots. Boundary of the hydrocarbon core region blue dots cytoplasmic side . Layer of lipid phosphates yellow dots. small Pfam PF00130 InterPro IPR002219 SMART C1 PROSITE PDOC00379 SCOP 2cpk TCDB OPM family 63 OPM protein 1ptr PDB PDB3 1ptr 231 280 PDB3 1ptq 231 280 PDB3 1xa6 A 215 267 PDB3 1y8f A 567 616 PDB3 1far 139 187 PDB3 1faq 139 187 PDB3 1kbf A 334 378 PDB3 1kbe A 334 378 PDB3 1r79 A 236 286 C1 domain also known as phorbol esters diacylglycerol binding domain binds an important secondary messenger diglyceride diacylglycerol DAG , as well as the analogous Phorbol phorbol esters ref name PUB00001427 cite journal author Azzi A, Boscoboinik D, Hensey C title The protein kinase C family journal Eur. J. Biochem. volume 208 issue 3 pages 547 557 year 1992 pmid 1396661 doi 10.1111 j.1432 1033.1992.tb17219.x ref . Phorbol esters can directly stimulate protein kinase C , PKC. The N terminal region of PKC, known as C1, has been shown ref name PUB00004685 cite journal author Kikkawa U, Nishizuka Y, Igarashi K, Fujii T, Ono Y, Kuno T, Tanaka C title Phorbol ester binding to protein kinase C requires a cysteine rich zinc finger like sequence journal Proc. Natl. Acad. Sci. U.S.A. volume 86 issue 13 pages 4868 4871 year 1989 pmid 2500657 doi 10.1073 pnas.86.13.4868 pmc 297516 ref Phorbol Phorbol esters such as 12 ... esters can directly stimulate PKC. The N terminal region of PKC, known as C1, binds PMA and DAG in a phospholipid and zinc dependent fashion. The C1 region contains one or two copies of a cysteine rich ... reflist External links UMichOPM families superfamily 63 Orientations of C1 domains in membranes OPM Protein domains DEFAULTSORT C1 Domain Category Peripheral membrane proteins Category Protein domains es Dominio C1 ... more details
Chembox verifiedrevid 416908601 ImageFile Chlorophyll c1.svg ImageSize IUPACName OtherNames Section1 Chembox Identifiers CASNo PubChem 25245630 SMILES Section2 Chembox Properties Formula C sub 35 sub H sub 30 sub O sub 5 sub N sub 4 sub Mg MolarMass 610.94 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Chlorophyll c1 is a form of chlorophyll . it makes a golden or brownish color and is an accessary pigment. it helps the organsim gather light but is not used in photosynthesis itself. biochem stub Plant pigments Category Tetrapyrroles Category Photosynthetic pigments eu Klorofila c1 ... more details
chembox verifiedrevid 361675148 Name Proanthocyanidin C1 ImageFile Proanthocyanidin C1.PNG ImageSize 200px ImageName Chemical structure of proanthocyanidin C1 ImageAlt Chemical structure of proanthocyanidin C1 IUPACName 2R,3R,4S 2 3,4 dihydroxyphenyl 4 2R,3R 2 3,4 dihydroxyphenyl 3,5,7 trihydroxy 3,4 dihydro 2H chromen 8 yl 8 2R,3R,4R 2 3,4 dihydroxyphenyl 3,5,7 trihydroxy 3,4 dihydro 2H chromen 4 yl 3,4 dihydro 2H chromene 3,5,7 triol OtherNames Procyanidin C1 br Procyanidol C1 br Epicatechin 4.beta. 8 epicatechin 4.beta. 8 epicatechin br Epicatechin 4 8 epicatechin 4 8 epicatechin Section1 Chembox Identifiers CASNo 37064 30 5 CASNo Ref CASOther PubChem 169853 SMILES C1C C OC2 C1C CC C2C3C C OC4 C C CC C34 O O C5C C OC6 CC CC C56 O O C7 CC C C C7 O O O C8 CC C C C8 O O O O O C9 CC C C C9 O O O InChI MeSHName Section2 Chembox Properties Formula C sub 45 sub H sub 38 sub O sub 18 sub MolarMass 866.77 g mol ExactMass 866.205814 u Appearance Density MeltingPt C BoilingPt C Solubility Proanthocyanidin C1 is a B type proanthocyanidin . It is an epicatechin trimer found in grape Vitis vinifera ref http cat.inist.fr ?aModele afficheN&cpsidt 1129642 Proanthocyanidin composition of red Vitis vinifera varieties from the Douro valley during ripening Influence of cultivation altitude. Mateus Nuno, Marques Sara, Goncalves Ana C., Machado Jos M. and De Freitas Victor, American journal of enology and viticulture, 2001, vol. 52, no2, pp. 115 121 ref . References reflist Proanthocyanidin category proanthocyanidins Natural phenol stub ... more details
primarysources date February 2010 Infobox software logo File Composite C1 logo.gif screenshot Image CompositeC1 screenshot.png 300px status Active license Mozilla Public License latest release version 2.1 latest release date release date 2011 03 11 operating system Microsoft Windows Windows Azure programming language C Sharp programming language C JavaScript XSLT genre Web content management system website http www.composite.net Composite C1 is a free open source .NET Framework .NET based web content management system ref Marcello Tonarelli, https community.dynamics.com product crm crmtechnical b marcellotonarelli archive 2010 12 13 composite c1 free open source content management system.aspx Composite C1 free open source content management system , Marcello Tonarelli s Microsoft Dynamics CRM Blog , Dec 13, 2010 ref . History Composite C1 development began mid 2007, it reached 1.0 in January 2009 and until September 2010 is was sold as a commercially licensed product primarily to customers in northern Europe. September 29th 2010 Composite released Composite C1 2.0 as free open source software under the Mozilla Public License, pledging to continue development on the free core and providing paid services ref Barb Mosher, http www.cmswire.com cms web cms composite c1 net web cms has gone open source 008853.php Composite C1 .NET Web CMS Has Gone Open Source , CMSWire , Oct 13, 2010 ref . October 2010 Composite C1 was added to the .NET 4 enabled parts of Microsoft s Web App Gallery Web Platform Installer 3 and WebMatrix . March 2011 Composite C1 2.1 was released making SQL Server support part of the open source project ref Dee Ann LeBlanc, http www.cmswire.com cms web cms alert whats coming for open source cms in april 2011 010704.php Alert What s Coming for Open Source CMS in April ... tracker and forum for Composite C1 is hosted at http CompositeC1.codeplex.com the CodePlex site also contain user ratings and reviews that can not be moderated. Modules C1 Packages Content versioning ... more details
unreferenced date February 2010 Infobox Locomotive name Pennsylvania Railroad C1 powertype Steam image PRR C1 6560.jpg caption PRR C1 locomotive 6560. Photographed at Cincinnati, Ohio , 28 June 1950 by Otto Perry designer builder Pennsylvania Railroad ordernumber serialnumber buildmodel builddate 1925, 1927 totalproduction 90 rebuilder rebuilddate numberrebuilt whytetype 0 8 0 uicclass Dh gauge RailGauge ussg driverdiameter convert 56 in m 3 abbr on minimumcurve wheelbase length width height axleload convert 74000 lb t 1 abbr on weightondrivers locoweight convert 278000 lb t 1 abbr on tenderweight locotenderweight tendertype fueltype fuelcap watercap tendercap sandcap boiler boilerpressure convert 250 psi MPa 2 abbr on feedwaterheater firearea tubearea fluearea tubesandflues fireboxarea totalsurface superheatertype superheaterarea cylindercount Two cylindersize convert 27 x 30 in mm 0 abbr on valvegear valvetype valvetravel valvelap valvelead topspeed poweroutput tractiveeffort convert 78154 lbf kN 1 abbr on factorofadhesion locobrakes locobrakeforce trainbrakes safety railroad railroadclass powerclass numinclass roadnumber 6550 6639 officialname nicknames axleloadclass locale deliverydate firstrundate lastrundate retiredate 1948 1953 preservedunits restoredate scrapdate disposition The PRR C1 was the Pennsylvania Railroad s class of 0 8 0 steam locomotives. They were commonly used in switching services on the system. While most railroads liked the 0 8 0 wheel arrangement, this particular wheel arrangement was not keen on the PRR. When the railroad needed bigger motive power, they preferred the 2 8 0 Consolidation Type. As a railroad the PRR wanted the best motive power to handle the switching chores that the railroad had to complete at yard s and Interchange freight rail interchanges . The engines were retired between 1948 and 1953. PRR locomotives Category Pennsylvania Railroad locomotives C1 Category 0 8 0 locomotives steam loco stub ... more details
Refimprove date January 2009 X 1106 C1 , also known as the Great Comet of 1106 , was a Great Comet that appeared on February 2, 1106, and was observed across the world from the beginning of February through to mid March. It was recorded by astronomers in Wales , England , Japan , Korea , China and Europe . It was observed to split in two, Fact date February 2007 and may have formed the Great Comet of 1882 , Comet Ikeya Seki and SOHO 620 . Fact date January 2009 It is a member of the Kreutz Sungrazers Kreutz Group , as Subfragment I, split from an earlier comet. Fact date January 2009 Observations Britain A brief note in the Welsh manuscript known as the Brut y Tywysogion reads in translation blockquote 1106 . In that year there was seen a star wonderful to behold, throwing out behind it a beam of light of the thickness of a pillar in size and of exceeding brightness, foreboding what would come to pass in the future for Henry IV, Holy Roman Emperor Henry , emperor of Rome, after mighty victories and a most pious life in Christ, went to his rest. And his son, after winning the seat of the empire of Rome, was made emperor. fact blockquote The 1106 annal of the Peterborough Chronicle describes the comet. The Dorothy Whitlock translation reads blockquote In the first week of Lent, on the Friday, 16 February, in the evening, there appeared an unusual star, and for a long time after that it was seen shining a while every evening. This star appeared in the south west it seemed small and dark. The ray that shone from it, however, was very bright, and seemed to be like an immense beam shining north east and one evening it appeared as if this beam were forking into many rays toward the star ... of Wales Press, Cardiff, 1955. Comet X 1106 C1 Publication der Sternwarte in Kiel, No. 6, pp ... Category 12th century in science Category 1106 comet stub de Gro er Komet von 1106 it X 1106 C1 pl X 1106 C1 sl Veliki komet iz leta 1106 zh 1106 ... more details
Infobox Ship Begin Infobox Ship Image Ship image Image HMS C38.jpg 300px HMS C38 Ship caption HMS C38 A typical C class submarine Infobox Ship Career Hide header Ship country UK Ship flag shipboxflag UK naval Ship name HMS C1 Ship ordered Ship awarded Ship builder Vickers , Barrow in Furness Barrow Ship laid down 13 November 1905 Ship launched 10 July 1906 Ship christened Ship acquired Ship commissioned 30 October 1906 Ship decommissioned Ship in service Ship out of service Ship renamed Ship reclassified Ship refit Ship struck Ship reinstated Ship fate Sold, 22 October 1920 Ship status Ship homeport Infobox Ship Characteristics Hide header Header caption Ship class British C class submarine C class submarine Ship type Ship tonnage Ship displacement convert 287 LT t 0 lk on abbr on surfaced br convert 316 LT t 0 abbr on submerged Ship length convert 143 ft 2 in m abbr on Ship beam convert 13 ft 6 in m abbr on Ship height Ship draught Ship depth Ship hold depth Ship decks Ship deck clearance Ship power Ship propulsion 600 hp Vickers petrol engine , 200 hp electric motor, 1 screw Ship speed convert 12 kn lk on surfaced br convert 7 kn submerged Ship range convert 1500 nmi km abbr on at convert 7 kn abbr on surfaced br convert 50 nmi km abbr on at convert 4.5 kn abbr on submerged Ship endurance Ship test depth Ship boats Ship complement 16 Ship time to activate Ship sensors Ship EW Ship armament 2 convert 18 in mm 0 abbr on torpedo tube s 2 torpedo es Ship armour Ship notes HMS C1 was a British C class submarine built by Vickers , Barrow in Furness Barrow . She was laid down on 13 November 1905, launched 10 July 1906 and was commissioned on 30 October 1906. C1 was equipped with wireless telegraphy . She was converted to a surface patrol boat and renamed S8 for Adriatic service. On 23 April 1918 she was packed with dynamite to be Zeebrugge Raid blown up at Zeebrugge Mole . However, this did not happen. C1 was sold 22 October 1920 to Stanlee, and resold 14 November 1921 t ... more details
al. title Genetic association study between senile dementia of Alzheimer s type and APOE C1 C2 gene ... Gene 19 stub Category Apolipoproteins ms APOC1 ru C1 ... more details
enzyme Name cytochrome c methionine S methyltransferase EC number 2.1.1.123 CAS number 93585 98 9 IUBMB EC number 2 1 1 123 GO code 0030783 image width caption Wikify date July 2009 In enzymology , a cytochrome c methionine S methyltransferase EC number 2.1.1.123 is an enzyme that catalysis catalyzes the chemical reaction S adenosyl L methionine cytochrome c methionine math rightleftharpoons math S adenosyl L homocysteine cytochrome c S methyl methionine Thus, the two substrate biochemistry substrates of this enzyme are S Adenosyl methionine S adenosyl methionine and cytochrome c methionine , whereas its two product chemistry products are S adenosylhomocysteine and cytochrome c S methyl methionine . This enzyme belongs to the family of transferase s, specifically those transferring one carbon group methyltransferases. The systematic name of this enzyme class is S adenosyl L methionine cytochrome c methionine S methyltransferase . References reflist 1 cite journal author Farooqui JZ, Tuck M, Paik WK year 1985 title Purification and characterization of enzymes from Euglena gracilis that methylate methionine and arginine residues of cytochrome c journal J. Biol. Chem. volume 260 pages 537&ndash 45 pmid 2981218 issue 1 DEFAULTSORT Cytochrome C Methionine S Methyltransferase Category EC 2.1.1 Category Enzymes of unknown structure transferase stub it citocromo c metionina S metiltransferasi ... more details
Image ETC.PNG thumb 300px Electron transport chain. Complex IV is at the right. Image Cytochrome C Oxidase 1OCC in Membrane 2.png thumb 300px The crystal structure of bovine cytochrome c oxidase in a phospholipid ... dimer in this structure The enzyme cytochrome c oxidase or Complex IV PDB 2OCC , EC number 1.9.3.1 ... or bacterial membrane. It receives an electron from each of four cytochrome c molecules, and transfers ... in the mitochondria. The complex contains two heme s, a cytochrome a and cytochrome a cytochrome ... Cytochrome c Oxidase at 2.8 journal Science volume 269 issue 5227 pages 1069 1074 doi 10.1126 science.7652554 ... 6&VInst PROD&VType PQD&RQT 309&VName PQD&TS 1290023610&clientId 15382 ref In fact, the cytochrome a sub 3 sub and Cu sub B sub form a binuclear center that is the site of oxygen reduction. Cytochrome c reduced by the preceding component of the respiratory chain cytochrome bc1 complex, complex III docks near the Cu sub A sub binuclear center, passing an electron to it and being oxidized back to cytochrome ... on to cytochrome a, which in turn passes an electron on to the cytochrome a sub 3 sub Cu sub B sub ... ion in the fully oxidized state. X ray crystallography Crystallographic studies of cytochrome ... 240 bovine enzyme numbering . It plays a vital role in enabling the cytochrome a sub 3 sub Cu sub B ... Biogenesis of Cytochrome c Oxidase journal Mitochondrion volume 5 issue 6 pages 363 383 url doi 10.1016 ..., A. year 2006 title Assembly of mitochondrial cytochrome c oxidase, a complicated and highly ... cytochrome c 8 H sup sup sub in sub O sub 2 sub 4 Fe sup 3 sup cytochrome c 2 H sub 2 sub O 4 H sup sup sub out sub Two electrons are passed from two cytochrome c s, through the Cu sub A sub and cytochrome a sites to the cytochrome a sub 3 sub Cu sub B sub binuclear center, reducing the metals to the Fe ... electrons coming from the Fe sup 2 sup cytochrome a sub 3 sub , which is converted to the ferryl oxo ... electron arising from another cytochrome c is passed through the first two electron carriers to the cytochrome ... more details
enzyme Name cytochrome b5 reductase EC number 1.6.2.2 CAS number 9032 25 1 IUBMB EC number 1 6 2 2 GO code 0004128 image NADH cytochrome B5 reductase 1UMK.png width caption Ribbon diagram of red blood cell erythrocytic methemoglobin reductase with FAD bound. From PDB 1UMK . Cytochrome b sub 5 sub reductase also known as methemoglobin reductase is a NADH dependent enzyme that converts methemoglobin to hemoglobin . It contains FAD and catalyzes the reaction center NADH H sup sup 2 ferricytochrome b sub 5 sub NAD sup sup 2 ferrocytochrome b sub 5 sub center The following four human genes encode cytochrome b sub 5 sub reductases CYB5R1 CYB5R2 CYB5R3 CYB5R4 See also Cytochrome b5 Methemoglobinemia Reductase External links MeshName Cytochrome B 5 Reductase PDB 1IB0 crystal structure of rat CBR complexed with NAD PDB 1NDH crystal structure of pig liver CBR PDB 1UMK crystal structure of human erythrocyte CBR InterPro IPR001834 InterPro entry for CBR NADH or NADPH oxidoreductases Flavoproteins Category EC 1.6.2 de Cytochrom b5 Reduktasen it Citocromo b5 reduttasi ja b5 ... more details
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