Infobox Non profit Non profit name CysticFibrosisFoundation Non profit logo Image CysticFibrosisFoundation ... of cysticfibrosis organizations Canadian CysticFibrosisFoundationCysticFibrosis Trust Association Gr gory Lemarchal NACFC References Reflist External links http www.cff.org CysticFibrosisFoundation http www.medicalnewstoday.com medicalnews.php?newsid 19241 CysticFibrosisFoundation Marks 50 Years in the Fight Against CysticFibrosis Category Charities based in the United States US philanthropy org stub fr CysticFibrosisFoundation tr Kistik Fibrozis Kurumu .... Beall, Ph.D., President and CEO area served USA focus Cysticfibrosis method revenue United States ... index.cfm bay search.summary orgid 9142.htm title Charity Navigator Rating CysticFibrosisFoundation publisher Charity Navigator accessdate 2007 10 02 ref endowment num employees owner Non profit slogan homepage http www.cff.org cff.org The CysticFibrosisFoundation CFF is a non profit organization in the United States established to provide the means to cure and control cysticfibrosis CF . The Foundation provides information about cysticfibrosis and finances CF research that aims to improve the quality of life for people with the disease. The Foundation also engages in legislative lobbying for cysticfibrosis. ref name about cite web url http www.cff.org aboutCFFoundation title About the CysticFibrosisFoundation publisher CysticFibrosisFoundation accessdate 2007 10 02 ref History The Foundation was established in 1955 by a group of volunteers in Philadelphia, Pennsylvania . In addition to providing Grant money grants for research into cysticfibrosis and supporting clinical trials, the foundation promotes and accredits 115 specialized centers for treatment of individuals with cysticfibrosis. The Foundation has over 80 chapters and offices across the US. In 1989, scientists working for the Foundation discovered the gene that causes cysticfibrosis, considered ... more details
Primary sources date January 2010 The CysticFibrosisFoundation from Slovenia Slovene Dru tvo za cisti no fibrozo Slovenije is a non profit organization in Slovenia , Europe. The foundation is a member of the European CysticFibrosis Society ECFS and CysticFibrosis Europe CFE , a section of international CF organization CysticFibrosis Worldwide CFW . History The foundation was established on 3 November 2009. Before it was a part of http www.dpbs.si Association of pulmonary and allergic patients in Slovenia Slovene Dru tvo plju nih in alergijskih bolnikov Slovenije Goals The purpose of association is organized to assist all patients affected with cysticfibrosis and their families to achieve the highest possible quality of life that contribute to a better and longer life of patients affected with cysticfibrosis. The society is intended to address and alleviate social distress and difficulties of people, providing assistance to people whose health or life is threatened, and the strengthening ... a delegation of the CysticFibrosisFoundation in Slovenia , 2009 http www.primorski.eu stories ... in CF External links http www.drustvocf.com Official webpage of CysticfibrosisFoundation from Slovenia http www.dpbs.si Dru tvo plju nih in alergijskih bolnikov Slovenije http www.cfww.org CysticFibrosis Worldwide CFW http www.ecfs.eu European CysticFibrosis Society ECFS http www.cff.org CysticFibrosisFoundation Category Charities Category Slovenian associations hr Dru tvo za cisti ku fibrozu ... to highlight the problems of patients with cysticfibrosis , newspaper Primorski dnevnik, 2009 http www.dnevnik.si novice zdravje 1042313407 The first European Week of awareness of the cysticfibrosis ... about the CF and various aspects of life of patients affected with it. See also List of cysticfibrosis organizations References http www.jana.si aktualno ljudje Njen boj za zivljenje.html Her fight ... The foundation s publications All publications are in pdf format and they are in Slovene language ... more details
logo fur Article CysticFibrosisFoundation Use Infobox ADDITIONAL INFORMATION Used for Owner Website http www.cff.org Common Images SevaCM images top CFFlogo.gif History Commentary OVERRIDE FIELDS Description Source Portion Low resolution Purpose Must be specified if Use is not Infobox Org Brand Product Replaceability other information Licensing Non free logo History of File Cff.gif 2007 10 03T04 45 43Z User Ani1 Ani1 User talk Ani1 Talk Special Contributions Ani1 contribs 599 bytes 2007 10 03T04 24 17Z User STBotI STBotI User talk STBotI Talk Special Contributions STBotI contribs 204 bytes nowiki This image has no rationale nowiki 2007 10 03T04 22 20Z User Ani1 Ani1 User talk Ani1 Talk Special Contributions Ani1 contribs 154 bytes nowiki CysticFibrosisFoundation USA logo from http www.cff.org Common Images SevaCM images top CFFlogo.gif nowiki 2007 10 03T04 22 20Z User Ani1 Ani1 User talk Ani1 Talk Special Contributions Ani1 contribs 190x74 4088 bytes ... more details
Infobox disease Name Cysticfibrosis Image CFtreatmentvest2.JPG Alt Caption A breathing treatment for cystic ... GeneReviewsID GeneReviewsName Cysticfibrosis also known as CF or mucoviscidosis is a recessive genetic ..., viscous secretions. ref name yankas cite journal title Cysticfibrosis adult care consensus conference ... doi 10.1378 chest.125.1 suppl.1S ref The name cysticfibrosis refers to the characteristic scar ... Andersen DH. Cysticfibrosis of the pancreas and its relation to celiac disease a clinical and pathological .... CF is caused by a mutation in the gene for the protein cysticfibrosis transmembrane conductance ... is needed to prevent cysticfibrosis. CF develops when neither gene works normally and therefore has ... F, Doring G Cysticfibrosis. Lancet. 2003 Feb 22 361 9358 681 9. ref ref http www.patient.co.uk doctor Cystic Fibrosis.htm Patient UK website CysticFibrosis ref The World Health Organization states that In the European ... genomics public geneticdiseases en index2.html ref Individuals with cysticfibrosis can be diagnosed ... is often necessary as CF worsens. Signs and symptoms File Cysticfibrosis manifestations.png 400px thumb right A diagram showing clinical manifestations of cysticfibrosis ref name isbn0 8089 ... fibrosis are salty tasting skin , ref name pmid17557942 cite journal author Quinton PM title Cystic ... in children with cysticfibrosis a review of published studies journal Eur. J. Endocrinol. volume ... in cysticfibrosis cohorting, cross contamination, and the respiratory therapist journal Respir Care ... in cysticfibrosis journal Gastroenterology volume 131 issue 4 pages 1030 9 year 2006 month October .... ref name pmid19393104 cite journal author Ratjen FA title Cysticfibrosis pathogenesis ... cases, cysticfibrosis can manifest itself as a coagulation disorder. A double recessive allele is needed for cysticfibrosis to be apparent. Young children are especially sensitive to vitamin K malabsorptive .... 2010 9 201 202. ref Lung and sinus Image CysticFibrosis Respiratory Infections by Age.svg ... more details
life into the future former name homepage URL cysticfibrosis.ca dissolved footnotes CysticFibrosis Canada , formerly the Canadian CysticFibrosisFoundation, is a Canada wide health Charitable organization ... ref See also Shinerama List of cysticfibrosis organizations CysticFibrosisFoundationCysticFibrosis ...Infobox non profit name CysticFibrosis Canada image File CysticFibrosis Canada 2011.png 160px The new logo and name CysticFibrosis Canada , 2011 onward. type Health Charity founded date start date 1960 ... 2009 Keeping a Promise accessdate 2010 12 21 date 2009 publisher CysticFibrosis Canada ref endowment ..., CysticFibrosis Canada celebrated its 50th Anniversary. CysticFibrosis Canada s mandate is to help individuals with cysticfibrosis , principally by funding cysticfibrosis research and care. The organization also provides educational materials for the cysticfibrosis community and the general public undertakes advocacy initiatives with, and on behalf of Canadians with cysticfibrosis, and raises funds to supports its programs. CysticFibrosis Canada is one of the world s largest non governmental granting agencies in the field of cysticfibrosis research. ref cite web url http www.cysticfibrosis.ca en research index.php title CysticFibrosis Canada Research accessdate 2011 01 31 date 2010 05 19 publisher CysticFibrosis Canada ref Mission CysticFibrosis Canada raises funds in order to promote public awareness and support research and high quality cysticfibrosis care. ref cite web url http www.cysticfibrosis.ca en aboutUs mission.php title CysticFibrosis Canada About us What we do Mission accessdate 2011 01 31 date 2009 08 06 publisher CysticFibrosis Canada ref Research and Care CysticFibrosis Canada s primary objective is to fund CF research and care the organization annually ... undertaking CF investigations. Each year, CysticFibrosis Canada awards more than 6 million in grants ... title CysticFibrosis Canada Research accessdate 2011 01 31 date 2010 05 19 publisher CysticFibrosis ... more details
Wikify date December 2011 For general diabetes discussion Diabetes Infobox disease Name Cysticfibrosis related diabetes Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic eMedicine mult MeshID Cysticfibrosis related diabetes CFRD is diabetes specifically caused by cysticfibrosis , a genetic condition. Cysticfibrosis related diabetes mellitus CFRD develops with age, and the median age at diagnosis is 21 years. ref name pmid20034372 cite journal author Lek N, Acerini CL title Cysticfibrosis related diabetes mellitus diagnostic and management challenges. journal Curr Diabetes Rev year 2010 volume 6 issue 1 pages 9 16 pmid 20034372 doi pmc url http www.ncbi.nlm.nih.gov entrez eutils elink.fcgi?dbfrom pubmed&tool sumsearch.org cite&retmode ref&cmd prlinks&id 20034372 ref See also Diabetes Diabetes mellitus Cysticfibrosis References references External links http www.cff.org LivingWithCF StayingHealthy Diet Diabetes CysticFibrosisFoundation, Guide to CysticFibrosis Related Diabetes Category Diabetes Category Pulmonology Category Endocrinology ... more details
Fund ref a U.K based foundation to help support families and their children with cysticfibrosis. CysticFibrosisFoundation Slovenia , a Slovenian association providing information and care for CF patiens ..., spouses, siblings, friends and significant others. Canadian CysticFibrosisFoundation http www.cysticfibrosis.ca CCFF , a Canada wide health charity, which funds cysticfibrosis research and care. As of February 2011, the Canadian CysticFibrosisFoundation will be known as CysticFibrosis Canada . CysticFibrosisFoundation CFF , a US non profit providing the means to cure and control cysticfibrosisCysticFibrosis Lifestyle Foundation ref http www.cflf.org index.php CysticFibrosis Lifestyle ... stronger and longer lives for themselves. Founded by Brian Callanan. CysticFibrosis Reaching Out Foundation ref http www.reachingoutfoundation.org CysticFibrosis Reaching Out Foundation ref , a US ... public CF awareness through an annual national CysticFibrosis Awareness observance Rock CF Foundation ... based foundation dedicated to raising money for fight against CysticFibrosis. Liam Foundation ref ... and enhancing the lives of those with CysticFibrosis. Mauli ola Foundation www.mauliola.org Based out ...The following organizations assist people with or do research into cysticfibrosis , a hereditary disease .... Australia CysticFibrosis Australia ref http www.cysticfibrosis.org.au CysticFibrosis Australia ref CFA , an Australian national organization aimed at raising awareness and education of cysticfibrosis ... others and search members. It is created by the CF community for the CF community. CysticFibrosis ... fibrosis European CysticFibrosis Society ref http www.ecfsoc.org European CysticFibrosis ... to information outreach and research for cysticfibrosis, named after the French singer and Star Academy France Star Academy winner Gr gory Lemarchal http www.ncfs.nl Nederlandse CysticFibrosis ... and support specific to cysticfibrosis. Operating since 1994, Cystic L serves people with CF ... more details
See also List of cysticfibrosis organizations CysticFibrosisFoundation Canadian CysticFibrosisFoundation References Reflist External links http www.cftrust.org.uk The CysticFibrosis Trust http cfgenetherapy.org.uk UK CysticFibrosis Gene Therapy Consortium Category Health charities in the United ...The CysticFibrosis Trust , founded in 1964, is the United Kingdom s only national charity dedicated to all aspects of cysticfibrosis CF . It funds research to treat and cure CF and aims to ensure appropriate clinical care and support for people with cysticfibrosis. Objectives Its objectives are To fund medical and scientific research provide effective treatments and develop a cure for cysticfibrosis To ensure appropriate clinical care for those with cysticfibrosis To provide information, advice, support and, where appropriate, financial assistance to anyone affected by cysticfibrosis Research The aim of the CysticFibrosis Trust research is to understand, treat and cure cysticfibrosis. The CysticFibrosis Trust is the major funder of medical and scientific CF research in the UK. The Trust ... future. Gene therapy aims to add a healthy copy of the faulty CF gene to the lung. The CysticFibrosis ... through the UK CysticFibrosis Gene Therapy Consortium . ref http cfgenetherapy.org.uk UK Cystic ... with cysticfibrosis. Clinical care Cysticfibrosis is a complex disease requiring considerable specialist ... CF treatment centres throughout the UK. Since 1997, the CysticFibrosis Trust has invested over 10 ... of tomorrow. The CysticFibrosis Trust sets national standard on clinical care, provides and funds ... of those with CF across the UK. Information, advice and support The CysticFibrosis Trust provides a confidential ..., schools and employers and anyone interested in cysticfibrosis. The Trust also advise families on benefits ... sales will go to the CysticFibrosis Trust while the exhibition describes the recessive gene inheritance pattern that causes ginger, or red, hair the same inheritance pattern that causes cysticfibrosis ... more details
Summary logo fur Article CysticFibrosis Canada Use Infobox ADDITIONAL INFORMATION Used for Owner CysticFibrosis Canada Website http www.cysticfibrosis.ca en aboutUs CysticFibrosisCanada.php CysticFibrosis Canada History Commentary OVERRIDE FIELDS Description Source Portion Low resolution Purpose Must be specified if Use is not Infobox Org Brand Product Replaceability Other information Licensing Non free logo ... more details
Children s Book Author, Actor, CysticFibrosis advocate, CEO President Travis Flores Children s Foundation www.tfcf.org valign top Boomer Esiason The Fight Against CysticFibrosis Gunnar Esiason 1991 ...The following notable people have or had cysticfibrosis . Note Please cite sources when adding entries to this list, non sourced entries will be removed class wikitable width 17 Name width 10 Life width 68 Comments width 5 Reference valign top Frankie Abernathy 1981 2007 Former cast member of MTVs The Real World San Diego appeared in 22 of the 25 episodes. ref cite web date June 12, 2007 url http www.mtv.com news articles 1562302 20070612 id 0.jhtml title Real World San Diego Alum Frankie Abernathy Dead At 25 publisher MTV accessdate 2007 06 12 ref valign top Dean Barnett 1967 2008 American conservative columnist and blogger. ref cite web date October 27, 2008 url http www.boston.com bostonglobe regional editions globe west west 2008 10 dean barnett a.html title Dean Barnett, conservative blogger, dead at 41 publisher Boston Globe accessdate 2008 10 27 ref valign top Lisa Bentley 1968 Canadian Ironman triathlete. ref cite web date July 7, 2004 url http www.cysticfibrosis.ca page.asp?id 237 title Lisa Bentley Triumphs Over CF publisher Canadian CysticFibrosisFoundation accessdate 2007 01 26 ref valign top Fraser Brown 2006 Son of former UK Prime Minister Gordon Brown . ref cite news ... s baby son diagnosed with cysticfibrosis publisher Times Online accessdate 2007 01 26 location ... scientists have suggested that his symptoms were more consistent with cysticfibrosis, unknown at the time ... reflist Category Lists of people by medical condition Cysticfibrosis ... Director for Grants and Scholarships at the Boomer Esiason Foundation BEF and the founder of Team ... 2F03 2F08 2Fnalice08.xml first Becky last Barrow title Pop singer dies after valiant battle with cysticfibrosis work Telegraph date 2003 07 03 accessdate 2007 02 23 location London ref valign top ... more details
PBB geneid 1080 Cysticfibrosis transmembrane conductance regulator CFTR is a protein ref name pmid16554808 ... whose failure causes cysticfibrosis journal Nature volume 440 issue 7083 pages 477 83 year 2006 ... Identification of the cysticfibrosis gene chromosome walking and jumping journal Science volume 245 ... J title A new model of cysticfibrosis pathology lack of transport of glutathione and its thiocyanate ... affect functioning of the chloride ion channels in these cell membranes, leading to cysticfibrosis ... widely known disorder cysticfibrosis . Both disorders arise from the blockage of the movement ... numbers. ref name pmid15888700 cite journal author Rowe SM, Miller S, Sorscher EJ title Cysticfibrosis ..., G551D, G542X, and R553X mutations among cysticfibrosis patients in the North of Brazil journal ..., Milgram SL title An apical PDZ protein anchors the cysticfibrosis transmembrane conductance regulator ... cysticfibrosis Cite pmid 16554808 ref Single CFTR channels open and close stochastically in an Adenosine ... in cysticfibrosis journal Am. J. Respir. Crit. Care Med. volume 175 issue 2 pages 174 83 year ... in the pathogenesis of cysticfibrosis and other inflammation related diseases journal ... duct and saltier sweat. This was the basis of a clinically important sweat test for cysticfibrosis ... Cysticfibrosis transmembrane conductance regulator has been shown to Protein protein interaction ... the maturation of the cysticfibrosis transmembrane conductance regulator journal J. Biol. Chem. volume ... cysticfibrosis transmembrane regulator plasma membrane expression journal J. Biol. Chem. volume ... chloride channel ClC 3B localizes to the Golgi and associates with cysticfibrosis transmembrane ... R C, Stutts M J, Milgram S L year 1998 month Jul. title An apical PDZ protein anchors the cysticfibrosis ... Shmuel, Kurtz Ira year 2002 month Dec. title The cysticfibrosis transmembrane conductance regulator ... binding consensus of the NHE RF PDZ1 domain matches the C terminal sequence of cysticfibrosis ... more details
ref improve date October 2011 cleanup date November 2009 Infobox Disease Name Fibrosis Image Cardiac amyloidosis very high mag movat.jpg Caption Micrograph of a heart showing fibrosis yellow left of image and amyloid deposition brown right of image . Movat s stain . DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID D005355 Fibrosis is the formation of excess fibrous connective tissue in an organ or tissue in a reparative or reactive process. This is as opposed to formation of fibrous tissue as a normal constituent of an organ or tissue. Scar ring is confluent fibrosis that obliterates the architecture of the underlying organ or tissue. The term is also sometimes used to describe a normal healing process, ref http dermnetnz.org pathology pathology glossary.html Glossary of dermatopathological terms. DermNet NZ Bot generated title ref but this usage is less common. Examples of fibrosis Image Cirrhosis high mag.jpg right thumb Micrograph showing cirrhosis of the liver. The tissue in this example is stained with a trichrome stain, in which fibrosis is colored blue. The red areas are the nodular liver tissue Pulmonary fibrosis lungs Idiopathic pulmonary fibrosis where the cause is unknown Cysticfibrosis Cirrhosis liver Endomyocardial fibrosis heart Mediastinal fibrosis soft tissue of the mediastinum Myelofibrosis bone marrow Retroperitoneal fibrosis soft tissue of the retroperitoneum Progressive massive fibrosis lungs a complication of coal workers pneumoconiosis Nephrogenic systemic fibrosis skin Crohn s Disease intestine Keloid skin Old myocardial infarction heart Scleroderma systemic sclerosis skin, lungs Arthrofibrosis knee, shoulder, other joints .... ref References reflist External links DorlandsDict three 000040106 Fibrosis http web.me.com nmsprs ... Diseases and disorders disease stub ... bg ca Fibrosi de Fibrose es Fibrosis fr Fibrose id Fibrosis it Fibrosi pt Fibrose ru sv Fibros ta uk zh ... more details
Pulmonary FibrosisFoundation What is Pulmonary Fibrosis? Last updated October 19, 2009 ref Symptoms Symptoms of pulmonary fibrosis are mainly Shortness of breath , particularly with exertion ...Image IPF amiodarone.JPG thumb A chest X ray demonstrating pulmonary fibrosis due to amiodarone . Pulmonary fibrosis is the formation or development of excess fibrous connective tissue fibrosis in the lung ... ref name pff Loss of appetite and rapid weight loss ref name pff Pulmonary fibrosis is suggested .... ref name medicinenet Cause See Interstitial lung disease Pulmonary fibrosis may be a secondary ... pff However, pulmonary fibrosis can also appear without any known cause. In this case, it is termed idiopathic . ref name nlm Most idiopathic cases are diagnosed as idiopathic pulmonary fibrosis . This is a diagnosis ... C has been found to exist in some families with a history of pulmonary fibrosis. ref name pff Diseases and conditions that may cause pulmonary fibrosis as a secondary effect include Inhalation of environmental ... pulmonaryfibrosis.html MedlinePlus Pulmonary Fibrosis Date last updated 09 February 2010 ref Hypersensitivity ... http www.medicinenet.com pulmonary fibrosis article.htm MedicineNet.com Pulmonary Fibrosis Retrieved ... pulmonary fibrosis a case report journal J Med Case Reports volume 2 issue pages 169 year 2008 pmid ... ref Radiation therapy to the chest ref name pff ref name medicinenet Pathogenesis See Fibrosis Pulmonary fibrosis involves gradual exchange of normal lung parenchyma with fibrotic tissue. The replacement ... name pff In addition, decreased compliance makes pulmonary fibrosis a restrictive lung disease . It is the main ... involve pulmonary fibrosis. Diagnosis The diagnosis can be confirmed by lung biopsy . ref ... to confirm the presence and pattern of fibrosis as well as presence of other features that may ... a pattern of so called non specific interstitial fibrosis. ref name medicinenet Misdiagnosis is common because, while overall pulmonary fibrosis is not rare, each individual type of pulmonary fibrosis ... more details
Expert subject Medicine date November 2008 Infobox disease Name Mediastinal fibrosis Image Caption DiseasesDB 30764 ICD10 ICD9 ICD9 519.3 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Mediastinal fibrosis is a rare late complication of histoplasmosis . It is characterized by invasive, calcified fibrosis centered on lymph nodes that block major vessels and airways. ref cite journal author Davis AM, Pierson RN, Loyd JE title Mediastinal fibrosis journal Seminars in respiratory infections volume 16 issue 2 pages 119 30 year 2001 pmid 11521244 doi 10.1053 srin.2001.24242 ref See also Mediastinum Mediastinitis References references External links Chorus 00762 Category Respiratory diseases Category Lymphatic system disease stub ... more details
Injection fibrosis is a complication of intramuscular injection , occurring especially often in infants and children. Injections are often delivered to the quadriceps , triceps , and gluteal muscles , and thus the complication often manifests itself in those muscles. Patients are unable to fully flexion flex the affected muscle. The condition is painless but progressively worsens over time. Orthopedic surgery is the typical treatment. ref cite journal author Mukherjee PK, Das AK. title Injection fibrosis in the quadriceps femoris muscle in children journal J Bone Joint Surg Am volume 62 issue 3 pages 453 6 year 1980 pmid 7364817 doi ref See also Fibrosis References references External links http injectionfibrosis.org Site that hosts many academic papers about injection fibrosis Category Musculoskeletal disorders disease stub ... more details
Infobox disease Name Bauxite fibrosis ICD10 ICD10 J 63 1 j 60 ICD9 ICD9 503 ICDO Image Bauxite with unweathered rock core. C 021.jpg Caption Bauxite with unweathered rock core OMIM MedlinePlus eMedicineSubj eMedicineTopic DiseasesDB Bauxite pneumoconiosis , also known as Shaver s disease , corundum smelter s lung , bauxite lung or bauxite smelters disease , is a progressive form of pneumoconiosis caused by exposure to bauxite fumes which contain aluminium and silica particulates. It is typically seen in workers involved in the smelting of bauxite to produce corundum . Presentation Initially, the disease appears as alveolitis , and then progresses to emphysema . Patients may develop pneumothorax collapsed lung . Respiratory pathology DEFAULTSORT Bauxite Fibrosis Category Lung diseases due to external agents disease stub ... more details
Infobox Disease Name Retroperitoneal fibrosis Image Caption DiseasesDB 11445 ICD10 ICD10 N 13 5 n 10 ICD9 ICD9 593.4 ICDO OMIM MedlinePlus eMedicineSubj radio eMedicineTopic 605 eMedicine mult eMedicine2 med 3664 MeshID D012185 Retroperitoneal fibrosis or Ormond s disease is a disease featuring the proliferation of fibrous tissue in the retroperitoneum , the compartment of the body containing the kidney s, aorta , renal tract and various other structures. It may present with lower back pain , renal failure , hypertension , deep vein thrombosis and other obstructive symptoms. It is named after John Kelso Ormond , who rediscovered the condition in 1948. ref WhoNamedIt synd 1712 Albarran Ormond syndrome ref ref cite journal author Ormond JK title Bilateral ureteral obstruction due to envelopment and compression by an inflammatory retroperitoneal process journal J Urol. volume 59 issue 6 pages 1072 9 year 1948 month pmid 18858051 ref ref cite journal author Ormond JK title Idiopathic retroperitoneal fibrosis a discussion of the etiology journal J Urol. volume 94 issue 4 pages 385 90 year 1965 month October pmid 5839568 doi url ref Causes Its association with various immune related conditions and response to immunosuppression have led to speculations as to the autoimmune disorder autoimmune etiology of idiopathic RPF. ref name pmid16427494 cite journal author Vaglio A, Salvarani C, Buzio C title Retroperitoneal fibrosis journal Lancet volume 367 issue 9506 pages 241 51 year 2006 month January pmid 16427494 doi 10.1016 S0140 6736 06 68035 5 url http linkinghub.elsevier.com retrieve pii S0140 6736 06 68035 5 ref One third of the cases are secondary to malignancy , medication methysergide ... of retroperitoneal fibrosis cannot be made on the basis of results of laboratory studies. CT is the best ... should also be done if the location of fibrosis is atypical or if there is an inadequate response .... ref name pmid12365466 cite journal author van Bommel EF title Retroperitoneal fibrosis journal ... more details
Cardiac fibrosis refers to an abnormal thickening of the heart valves due to inappropriate proliferation of cardiac fibroblasts. Fibrocyte cells normally secrete collagen , and function to provide structural support for the heart. When over activated this process causes thickening and fibrosis of the valve, with white tissue building up primarily on the tricuspid valve , but also occurring on the pulmonary valve . The thickening and loss of flexibility eventually may lead to valvular dysfunction ... of mostly right sided cardiac fibrosis which can be identified at autopsy. This pathology has also ... of serotonin. Connection with direct serotonergic agonist drugs Elevated prevalence of cardiac fibrosis ... , chlorphentermine , and aminorex induce a similar pattern of cardiac fibrosis and also pulmonary ... effects , as well as retroperitoneal fibrosis a fibrotic cell fibrocyte proliferation effect, thought to be similar to cardiac valve fibrosis . These include ergotamine and methysergide . Both drugs can also cause cardiac fibrosis. ref http books.google.com books?id AW7M6jBixj4C&pg PA626&lpg PA626 ... 5 HT sub 2B sub receptors as well, and have been reported to cause cardiac fibrosis. An example is pergolide . The drug was in decreasing use since reported in 2003 to be associated with cardiac fibrosis ... supports the concept of a crucial role for 5 HT2B receptor agonism in cardiac valvular fibrosis journal ... found that they did have heart valve changes suggestive of early cardiac fibrosis, which were not present ... yet to be reported to be associated with valve disease or other fibrosis, but for the previous ... carbidopa. Possible treatments The most obvious treatment for cardiac valve fibrosis or fibrosis ... fibrosis. ref Cite pmid 15498824 ref ref Cite pmid 18356487 ref ref Cite pmid 19049292 ref More sophisticated approaches of countering cardiac fibrosis like microRNA inhibition MIRN21 miR 21 , for example are being tested in animal models. References Reflist 2 Heart diseases DEFAULTSORT Cardiac Fibrosis ... more details
Infobox Artery Name Cystic artery Latin arteria cystica GraySubject 154 GrayPage 605 Image Gray532.png Caption The cystic artery branches from the hepatic artery proper . Image2 Bilebladder.png Caption2 ... hepatic artery BranchTo Superior branch BR Deep branch Vein Cystic vein Supplies Gall bladder and cystic duct MeshName MeshNumber DorlandsPre a 61 DorlandsSuf 12154087 The cystic artery supplies oxygenated blood to the gallbladder and cystic duct . Most common arrangement In the classic arrangement, occurring with a frequency of approximately 70 , a singular cystic artery originates from the geniculate ... name Balija Balija M, Huis M, Nikolic V, Stulhofer M. Laparoscopic visualization of the cystic artery ... from the right hepatic artery, the cystic artery travels superiorly to the cystic duct and produces 2 to 4 minor branches, known as Calot s arteries , that supply part of the cystic duct and cervix ... Double cystic artery When superficial and deep branches of the cystic artery do not share a common origin it is defined as a double cystic artery occurring with a frequency of 15 . The deep branch ... or retroduodenal artery . Approximately half of superficial cystic arteries have been shown to enter through the hepatobiliary triangle, while deep cystic arteries are often quite small in length and diameter. Tripling of the cystic artery is very rare, occurring in between 0 0.3 of cases. Aberrant ... and form of the cystic artery, with the most frequent variation resulting from an aberrant origin ... posterior and parallel to the cystic duct. ref Mlakar Bostjan, Gadzijev Eldar M, Ravnik Dean, Hribernik Marija. Anatomical Variations of the Cystic Artery. Eur J Morph. 2003 41 31 34. PMID 15121546 ... or Moynihan s hump may form and this artery generally produces multiple short cystic branches rather than a single cystic artery. ref name Hugh Hugh Thomas B, Kelly Michael D, Li Bei. Laparoscopic Anatomy of the Cystic Artery. Am J Surg. 1992 163 393 395. PMID 1534464 ref Left hepatic artery ... more details
Infobox Disease Name Cystic nephroma Image Cystic nephroma low mag.jpg Caption Micrograph of a cystic nephroma left of image . Normal kidney is seen on the right. H&E stain . DiseasesDB ICD10 ICD10 D 30 0 d 10 ICD9 ICD9 223.0 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID A cystic nephroma , also known as multilocular cystic nephroma , mixed epithelial stromal tumour MEST and renal epithelial stromal tumour REST , ref name pmid17414095 cite journal author Turbiner J, Amin MB, Humphrey PA, et al. title Cystic nephroma and mixed epithelial and stromal tumor of kidney a detailed clinicopathologic analysis of 34 cases and proposal for renal epithelial and stromal tumor REST as a unifying term journal Am. J. Surg. Pathol. volume 31 issue 4 pages 489 500 year 2007 month April pmid 17414095 doi 10.1097 PAS.0b013e31802bdd56 url ref is a type of rare benign kidney tumour . Symptoms Cystic nephromas are often asymptomatic. They are typically discovered on medical imaging incidentally i.e. an incidentaloma . Diagnosis Cystic nephromas are diagnosed by biopsy or excision. It is important to correctly diagnose them as, radiologically, they may mimic the appearance of a renal cell carcinoma that is cystic. ref Small JE et al. Cystic Nephroma. BrighamRAD Teaching Case Database. URL http brighamrad.harvard.edu Cases bwh hcache 385 full.html http brighamrad.harvard.edu Cases bwh hcache 385 full.html . Accessed July 25, 2009. ref Pathologic diagnosis Image Cystic nephroma high mag.jpg thumb right 250px High magnification micrograph of a cystic nephroma showing the characteristic simple ... . The characteristics of cystic nephromas are Cyst s lined by a simple epithelium with a hobnail ... w cytoplasm cytoplasm . Cystic nephromas have an immunostaining pattern like ovarian stroma they are positive ... PR and w CD10 CD10 . Additional images gallery Image Cystic nephroma intermed mag.jpg Micrograph of a cystic nephroma . H&E stain . gallery References reflist Urologic neoplasia Category Benign ... more details
Infobox Vein Name PAGENAME Latin vena cystica GraySubject 174 GrayPage 682 Image Gray591.png Caption The portal vein and its tributaries. Image2 Caption2 DrainsFrom gallbladder Source DrainsTo hepatic portal vein Artery cystic artery MeshName MeshNumber DorlandsPre v 05 DorlandsSuf 12850070 The cystic vein drains the blood from the gall bladder , and, accompanying the cystic duct , usually ends in the right branch of the Hepatic portal vein portal vein . External links cite journal author Fine A title The cystic vein the significance of a forgotten anatomic landmark journal JSLS volume 1 issue 3 pages 263 6 year 1997 pmid 9876684 pmc 3016730 Gray s circulatory stub Veins of the torso Category Veins of the torso es Vena c stica pt Veia c stica ... more details
Infobox Anatomy Name Cystic duct Latin ductus cysticus GraySubject 250 GrayPage 1198 Image illu liver gallbladder.jpg Caption 1 Right lobe of liver BR 2 Left lobe of liver BR 3 Quadrate lobe of liver BR 4 Round ligament of liver BR 5 Falciform ligament BR 6 Caudate lobe of liver BR 7 Inferior vena cava BR 8 Common bile duct BR 9 Hepatic artery BR 10 Portal vein BR 11 Cystic duct BR 12 Hepatic duct BR 13 Gallbladder BR Precursor System Artery cystic artery Vein Nerve Lymph MeshName MeshNumber DorlandsPre d 29 DorlandsSuf 12314797 Bile ducts and pancreas The cystic duct is the short Duct anatomy duct that joins the gall bladder to the common bile duct . It usually lies next to the cystic artery . It is of variable length. It contains a Spiral valves of Heister spiral valve , which does not provide much resistance to the flow of bile. Function Bile can flow in both directions between the gallbladder and the common hepatic duct and the common bile duct. In this way, bile is stored in the gallbladder in between meal times. The hormone cholecystokinin , when stimulated by a fatty meal, promotes bile secretion by increased production of hepatic bile, contraction of the gall bladder, and relaxation of the Sphincter of Oddi . Clinical significance Gallstones can enter and obstruct the cystic duct, preventing the flow of bile. The increased pressure in the gallbladder leads to swelling and pain. This pain is sometimes referred to as a gallbladder attack because of its sudden onset. During a cholecystectomy , the cystic duct is clipped two or three times and a cut is made between the clips, freeing the gallbladder to be taken out. See also Accessory bile duct Additional images gallery Image Digestive system showing bile duct.png Digestive system diagram showing the cystic duct Image Gray1095 gall bladder.png The gall bladder and bile ducts laid open. Image Bilebladder.png The portal vein and its tributaries. gallery External links eMedicineDictionary cystic duct SUNYAnatomyFigs ... more details
Infobox disease Name Cystic eyeball Image Alt Caption DiseasesDB ICD10 ICD10 Q 11 0 q 10 ICD9 ICD9 743.03 ICDO OMIM MedlinePlus eMedicineSubj eMedicineTopic MeshID Congenital cystic eye also known as CCE or cystic eyeball is an extremely rare Human eye ocular malformation where the eye fails to develop correctly in utero and is replaced by benign , fluid filled Tissue biology tissue . ref http www.biomedcentral.com 1471 2415 3 7 BioMed Central Full text Congenital cystic eye with multiple dermal appendages a case report Bot generated title ref Its incidence epidemiology incidence is unknown, due to the very small number of cases reported. An audit by Duke Elder of the medical literature in English language English from 1880 to 1963 discovered only 28 cases. The term was coined in 1937 by the renowned ophthalmologist Ida Mann . ref http www.ijo.in article.asp?issn 0301 4738 year 1987 volume 35 issue 2 spage 88 epage 91 aulast Pillai Congenital cystic eye A case report with CT scan Pillai AM, R, Sambasivan M, Indian J Ophthalmol Bot generated title ref Embryology Embryologically , the Congenital disorder defect is thought to occur around day 35 of gestation , when the Optic vesicles vesicle fails to invaginate . Dysgenesis of the vesicle later in development may result in coloboma , a separate and less severe malformation of the ocular structures. CCE is almost always unilateral , but at least 2 cases of wikt bilateral bilateral involvement have been described. Patients may also present with cutaneous appendages attached to the skin surrounding the eyes. Therapy Treatment of CCE is usually by enucleation of the eye enucleation , followed by insertion of an ocular implant medicine implant and prosthesis . References reflist Congenital malformations and deformations of eye DEFAULTSORT Congenital Cystic Eye Category Congenital disorders of eyes eye stub ... more details
Infobox disease Name Cystic hygroma Image Lymphangioma.jpg Caption Santhi Vardhan Kothapalli. This picture was taken in 1989. He has undergone four major surgeries in Apollo Hospital, Chennai. ICD10 D18.1, Q87.8 ILDS D18.140 ICD9 ICD9 228.1 ICDO M9173 0 OMIM 257350 MedlinePlus 000148 DiseasesDB 3374 eMedicineSubj ped eMedicineTopic 536 MeshID D018191 Image Posterior triangle of the neck.PNG right thumb 250px Cystic hygromas are classically found in the posterior triangle of the neck purple . A cystic hygroma is a congenital multiloculated lymphatic lesion that can arise anywhere, but is classically found in the left posterior triangle of the neck . This is the most common form of lymphangioma . It contains large cyst like cavities containing watery fluid. Microscopically cystic hygroma consists of multiple locules filled with lymph. In the depth the locules are quite big but they decrease in size towards the surface. Cystic hygromas are benign , but can be Disfigurement disfiguring . It is a condition which affects children very rarely it can present in adulthood ref cite journal author Gow L, Gulati R, Khan A, Mihaimeed F title Adult onset cystic hygroma a case report and review of management journal Grand Rounds volume 11 pages 5 11 year 2011 doi 10.1102 1470 5206.2011.0002 url http www.grandrounds e med.com articles gr110002.htm ref . It can be associated with a nuchal lymphangioma or a fetal hydrops ref Schwartz s principles of surgery self assessment and board review, 8th edition, chapter 38, page 257 textbook p.1476 ref It can be associated with Turner syndrome . ref name pmid19202339 cite journal author Alpman A, Cogulu O, Akgul M, et al. title Prenatally Diagnosed Turner Syndrome and Cystic Hygroma Incidence and Reasons for Referrals journal Fetal. Diagn. Ther. volume ... Wapner Kurtz syndrome that in addition to cystic hygroma, includes lymphedema and cleft palate. ref ... HP.3105 at http www.humpath.com humpath.com DEFAULTSORT Cystic Hygroma Category Congenital disorders ... more details
Infobox Disease Name Congenital hepatic fibrosis Image Caption DiseasesDB ICD10 ICD9 ICDO OMIM MedlinePlus eMedicineSubj ped eMedicineTopic 459 MeshID Congenital hepatic fibrosis is an heredity inherited fibrocystic liver disease associated with proliferation of interlobular bile ducts within the portal areas and fibrosis that do not alter hepatic lobule hepatic lobular architecture. The fibrosis would affect resistance in portal veins leading to portal hypertension . Overview The condition is usually congenital, but sporadic cases have also been reported. It may be associated with other congenital defects, commonly with autosomal recessive polycystic kidney disease , the most severe form of PKD. Some suggest that these two conditions are one disorder with different presentation. ref cite web url http www.emedicine.com ped topic459.htm title eMedicine Congenital Hepatic Fibrosis Article by Hisham Nazer, MBBCh, FRCP accessdate 2007 06 30 work ref Image autorecessive.svg thumb right Congenital hepatic fibrosis has an Recessive gene autosomal recessive pattern of inheritance. Embryogenesis Embryogenically , CHF is due to malformation of the duct plate , a round structure appearing in the eighth week of gestation that is formed by primitive hepatocytes , which differentiate into cholangiocytes . ref cite journal author Jorge OA, Jorge AD title Congenital hepatic fibrosis associated with von Recklinghausen s disease journal Revista espa ola de enfermedades digestivas organo oficial de la Sociedad Espa ola de Patolog a Digestiva volume 98 issue 9 pages 693 7 year 2006 pmid 17092201 doi ref CHF usually presents in adolescent or young adulthood, but onset of signs and symptoms can ... www.ncbi.nlm.nih.gov bookshelf br.fcgi?book gene&part hepatic fibrosis GeneReviews NCBI NIH UW entry on Congenital Hepatic Fibrosis Overview References reflist Cystic diseases DEFAULTSORT Congenital Hepatic Fibrosis Category Autosomal recessive disorders Category Diseases of liver med stub de Kongenitale ... more details