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  1. Cretinism

    This article is about the medical term. For the Marxist political concept, see Parliamentary cretinism . For the Roman Catholic Bishop, see Joseph Cr tin . File Cretin Child 1 .jpg thumb right 250px Cretin child Infobox Disease Name Congenital iodine deficiency syndrome Image Caption DiseasesDB 6612 ICD10 ICD10 E 00 e 00 ICD9 ICD9 243 ICDO OMIM MedlinePlus eMedicineSubj ped eMedicineTopic 501 MeshName Cretinism MeshNumber C05.116.099.343.347 File Cretin Child 2 .jpg thumb right 200px Cretin child Cretinism is a condition of severely stunted physical and mental growth due to untreated congenital disorder congenital deficiency of thyroid hormone s congenital hypothyroidism due to maternal nutritional deficiency of iodine . Etymology and use of cretin The term cretin is a medical term which describes a person so affected with the condition, but, as with words such as spastic and lunatic , it can ... cretinism due to congenital hypothyroidism Congenital hypothyroidism can be endemic, genetic ... cretinism results from abnormal development or function of the foetal thyroid gland. This type of cretinism has been almost completely eliminated in developed countries by early diagnosis by newborn ... cb0000 more than 800 div Cretinism arises from a diet deficient in iodine . It has affected many ... title Cretinism Revisited journal Clinical Endocrinology and Metabolism volume 24 issue 1 page pages ... cretinism was especially common in areas of southern Europe around the Alps and was described by ancient ... , 2000, Grove Press, p. 179 ref Alpine cretinism was described from a medical perspective ..., where soil is poor in iodine, cases of cretinism were very abundant and even considered genetically ... of the relationships of sporadic cretinism with congenital hypothyroidism, and of endemic cretinism ... cretinism.html Cretinism Research in Mental Handicap Endocrine pathology Category Pejorative ... pt Cretinismo ro Cretinism ru scn Cretinu sl Kretenizem fi Kretinismi sv Kretinism ta ...   more details



  1. Parliamentary cretinism

    Orphan date October 2007 Parliamentary cretinism is a pejorative term originally coined by Karl Marx in chapter five of his Eighteenth Brumaire of Louis Bonaparte ref http www.marxists.org archive marx works 1852 18th brumaire index.htm 18th Brumaire of Louis Bonaparte. Marx 1852 Bot generated title ref , published in 1852 following French coup of 1851 Louis Napoleon s coup d tat in France . It describes the belief that a socialist society can be achieved by peaceful, parliamentary means. Marx and Engels considered this a fatal delusion for the socialist movement, believing it would only waste time and allow reactionary forces to grow stronger. In the words of Friedrich Engels Quote Parliamentary cretinism is an incurable disease, an ailment whose unfortunate victims are permeated by the lofty conviction that the whole world, its history and its future are directed and determined by a majority of votes of just that very representative institution that has the honour of having them in the capacity of its members. ref http www.marxists.org glossary terms p a.htm Glossary of Terms Pa Bot generated title ref References references Category Communist theory Poli term stub hist stub ...   more details



  1. Goldstein's Toe Sign

    Goldstein s Toe Sign is a feature identified by Hyman I. Goldstein Dr. Hyman Isaac Goldstein 1887 1954 , an American physician and medical historian . A greater distance separates the largest two toes of some people exhibiting Down s Syndrome or cretinism . ref http www.whonamedit.com synd.cfm 3805.html Who Named It Website ref References references Wide distance between the great toe and the adjoining toe associated with cretinism and trisomy 21. Category Medical signs med sign stub ...   more details



  1. Kocher-Debre-Semelaigne syndrome

    Unreferenced date December 2009 The Kocher Debr Semelaigne syndrome is a myopathy of hypothyroidism in infancy or childhood characterised by lower extremity or generalized muscular hypertrophy, myxoedema , short stature and cretinism . The absence of painful spasms and pseudomyotonia differentiates this syndrome from Hoffmann syndrome . The syndrome is named after Emil Theodor Kocher , Robert Debr and Georges Semelaigne. Also known as Debre Semelaigne syndrome or cretinism muscular hypertrophy, hypothyroid myopathy, hypothyroidism large muscle syndrome, hypothyreotic muscular hypertrophy in children, infantile myxoedema muscular hypertrophy, myopathy myxoedema syndrome, myxoedema muscular hypertrophy syndrome, myxoedema myotonic dystrophy syndrome. DEFAULTSORT Kocher Debre Semelaigne Syndrome Nervoussystem disease stub Category Syndromes ...   more details



  1. E0

    Letter NumberCombination E1 D0 F0 E0 or E00 can refer to Epsilon naught &epsilon sub 0 sub , in mathematics, the smallest transfinite ordinal number satisfying math varepsilon 0 omega varepsilon 0 math Vacuum permittivity &epsilon sub 0 sub , in physics, the fundamental vacuum permittivity constant E0 cipher , a cipher used in the Bluetooth protocol E0 robot , a 1986 humanoid robot by Honda E sup s o s sup , the standard electrode potential E0, the digital carrier for audio, specified in G.703 Eos Airlines IATA code E00, Cretinism ICD 10 code Letter NumberCombDisambig fr E0 it E0 pl e0 ...   more details



  1. Gibbus deformity

    Orphan date February 2009 A Gibbus Deformity is a form of structural kyphosis . When viewed from behind, the deformity is sharply angled, and the resulting humpback is more easily seen when bending forward. ref http www.spineuniverse.com displayarticle.php article1437.html ref Gibbus deformity can be a sequela of advanced skeletal tuberculosis , and is the result of collapse of vertebra l bodies. ref Kasper D.L. et al., Harrisons principles of internal medicine, 16.ed, 2005 p.958 ref A Gibbus deformity may result from the sail vertebrae associated with cretinism , the childhood form of hypothyroidism . References reflist Category Skeletal disorders medicine stub ...   more details



  1. Rodrigo Fierro

    Rodrigo Fierro Ben tez , M.D., Ph.D., Ambato, 1930 is an Ecuadorean M.D., writer and politician. He was Minister of Public Health of the Republic of Ecuador during the government of Jaime Rold s Aguilera , 1979 1981. He received the The Franklin Institute Awards Bolton S. Corson Medal in 1993. Sources 1. Carlos Emilio Grijalva, Genealog a de la familia Fierro, Hierro y del Hierro , Tulc n, junio de 1937. br 2. Rodrigo Fierro Ben tez, Estoy Haciendo una vida de Perseguido , Revista La Casa , No. 67, CCE, Quito, 2009. br 3. http www.conmemoracionescivicas.gov.ec es publicaciones cc31.pdf br 4. http www.fi.edu winners 1993 fierrobenitez rodrigo.faw?winner id 2790 Bibliography Rodrigo Fierro Ben tez, John B. Stanbury, Andries Querido, Leslie Degroot, Rodrigo Alb n and Jorge C rdova, Endemic Cretinism in the Andean Region of Ecuador , Journal of Clinical Endocrinology & Metabolism Vol. 30, No. 2, 228 236. Rodrigo Fierro Benitez M.D., Ignacio Ramirez M.D., Juan Garc s M.D., Carlos Jaramillo M.D., Fausto Moncayo M.D., and John B. Stanbury M.D., The clinical pattern of cretinism as seen in highland Ecuador , American Journal of Clinical Nutrition, Vol 27, 531 543. Rodrigo Fierro Ben tez, Cap tulos de la biopatolog a andina los des rdenes por deficiencia de yodo , Universidad Andina Sim n Bol var Corporaci n Editora Nacional, 1993. Persondata Metadata see Wikipedia Persondata . NAME ALTERNATIVE NAMES SHORT DESCRIPTION DATE OF BIRTH PLACE OF BIRTH DATE OF DEATH PLACE OF DEATH Category Living people es Rodrigo Fierro ...   more details



  1. Neonatal heel prick

    File Neonatal heel prick Flanders.jpg thumb The neonatal heel prick is a common procedure for taking a blood sample from the heel of newborn infant s. A pinprick puncture is made in the heel of the infant s foot, and blood from the foot is soaked into pre printed collection cards known as Guthrie cards. ref http www.abc.net.au catalyst stories s867619.htm Guthrie Cards , Catalyst TV program Catalyst ABC1 , 29 May 2003. ref The blood samples can be used for a variety of Genetic testing genetic tests , including Thyroid stimulating hormone TSH to detect hypothyroidism and hence prevent cretinism . Trypsin to detect cystic fibrosis . Detection of phenylketonuria , an enzyme deficiency that can impair brain development. Other potential tests include A test for galactosemia It is recommended that the screening test be performed when the infant is between 48 and 72 hours of age. False positives and negatives can sometimes occur when the screening tests are performed before 48 hours. ref http www.health.vic.gov.au genetics nbs.htm Newborn screening guidelines , Government of Victoria , 13 December 2007. ref With genetic tests becoming more common, a wide variety of tests may use the blood drawn by this method. Many neonatal units SCBUs now use this method to carry out the daily blood tests blood count, electrolytes required to check the progress of ill neonates. In the UK, the National Health Service NHS test for Hypothyroidism Cystic fibrosis Phenylketonuria PKU Medium chain acyl coenzyme A dehydrogenase deficiency MCADD Sickle cell disease ref http www.screening.nhs.uk an index.htm ref See also Heel stick wound Newborn screening References reflist External links http www.gpnotebook.co.uk simplepage.cfm?ID x20060628142653816440 Category Midwifery Category Pediatrics ...   more details



  1. Infantilism (physiological disorder)

    wiktionarypar infantilism infantile See Infantilism for other uses of the term In medicine , Infantilism is an obsolete term for various, often unrelated Disease disorder s Human development biology human development , up to developmental disability , which consist of retention of the physical and or psychological characteristics of early developmental stages infant , child into a relatively advanced age. ref name gordon Ronald Grey Gordon a 1999 reprint Personality , Routledge, ISBN 0415210577, http books.google.com books?id FYqpXudW6MYC&printsec toc&dq 22infantilism is 22 PPA77,M1 p.77 ref Various types of infantilism were recognized, lumped together in the above superficial description. With better understanding of the endocrine system and genetic disorder s, various disorders which included the word infantilism received other names. For example, Brissaud s infantilism, described by douard Brissaud in 1907 is now known as myxedema a form of hypothyroidism intestinal infantilism of Christian Archibald Herter is called coeliac disease . The Turner syndrome was described as a syndrome of infantilism by Henry Turner endocrinologist Henry Turner himself. ref Turner HH. 1938 . A syndrome of infantilism, congenital webbed neck, and cubitus valgus. Endocrinology . 23 566 574. ref Terms such as genital infantilism infantilism in development of genitals, hypogenitalism , or sexual infantilism lack of sexual development after expected puberty or delayed puberty may still be seen, and are considered to be synonyms of hypogonadism . Somatic infantilism refers to infantilism of overall bodily development. Speech infantilism is a speech disorder. Similarly to some other medical terms cretinism , Idiot usage idiot ism , infantilism infantile may be used pejoratively synonymous to Maturity psychological immature , retard . ref http dictionary.reference.com browse infantilism Infantilism , a dictionary entry ref References references DEFAULTSORT Infantilism Disorder Category Deve ...   more details



  1. Isidre Nonell

    run by Vallmitjana s family. There, he saw a large number of people suffering from the illness of cretinism ... from the Spanish American War Cuban war , and people suffering from cretinism . Though, his magazine ...   more details



  1. Macroglossia

    Refimprove date March 2009 Infobox Disease Name Macroglossia Image Caption DiseasesDB 7689 ICD10 ICD10 Q 38 2 q 38 ICD9 ICD9 529.8 ICDO OMIM 153630 MedlinePlus eMedicineSubj ent eMedicineTopic 746 MeshID D008260 Macroglossia is the medical term for unusual enlargement Organ hypertrophy hypertrophy of the tongue . Severe enlargement of the tongue can cause cosmetic and functional difficulties including in speaking, eating, swallowing and sleeping. Causes Amyloid Disorders Amyloidosis is an accumulation of insoluble proteins in tissues that impedes normal function. ref Merck Manual 17th Ed. ref 1. Primary amyloidosis 2. Myeloma associated amyloidosis ref http sciencelinks.jp j east article 200318 000020031803A0392321.php ref 3. Lubarsch Pick syndrome ref http en.wikipedia.org wiki Ludwig Pick ref 4. Immunoglobulinemic amyloidosis Hypothyroid Macroglossia Macroglossia is also a clinical feature in Hypothyroid disorders which include 1 . congenital hypothyroidism , ref name pmid1739345 cite journal author Grant DB, Smith I, Fuggle PW, Tokar S, Chapple J title Congenital hypothyroidism detected by neonatal screening relationship between biochemical severity and early clinical features journal Arch. Dis. Child. volume 67 issue 1 pages 87 90 year 1992 month January pmid 1739345 pmc 1793539 doi 10.1136 adc.67.1.87 url ref . 2 . Young Simpson syndrome , ref http sciencelinks.jp j east article 200223 000020022302A0895118.php ref 3 . Zadik Barak Levin syndrome , ref http en.wikipedia.org wiki Zadik Barak Levin syndrome ref 4 . Athyreotic cretinism 5 . Kocher Debre Semelaigne syndrome ref http www.springerlink.com content lh807890491x17h3 ref Overgrowth Disorders 1. Beckwith Wiedemann syndrome ref http www.joms.org article S0278 2391 00 69867 1 abstract ref 2. Simpson Golabi Behmel syndrome ref http www.ncbi.nlm.nih.gov entrez dispomim.cgi?id 312870 ref 3. Acromegaly Chromosomal disorders 1. Triploid Syndrome br 2. Chromosome 4,trisomy 4p Other Miscellaneous 1. Mucopolysacchari ...   more details



  1. Basil Hetzel

    Cleanup date August 2007 Basil Stuart Hetzel , Order of Australia AC born 13 June 1922 is an Australia n medical researcher who has made a major contribution to combating iodine deficiency , a major cause of goitre and cretin ism world wide. Academic career Hetzel graduated in medicine from the University of Adelaide in the 1940s. He was held a Fulbright Program Fulbright Research Scholar in the 1950s. He returned to Adelaide and was employed as Reader and then Michell Professor of Medicine at the Queen Elizabeth Hospital, Adelaide , University of Adelaide before moving to Monash University as the Foundation Professor of Social and Preventive Medicine . He also held the position of first chief of the CSIRO Division of Human Nutrition, Chair of the University of South Australia s Bob Hawke Prime Ministerial Centre, and University of South Australia Chancellor 1992&ndash 1998, Research Hetzel worked in remote areas of Papua New Guinea with the Public Health Department of the then Territory, and his research concluded that the endemic goitre and associated cretinism was attributable to an iodine deficient diet. He also demonstrated that dietary supplementation would entirely prevent these illnesses. In the 1980s Hetzel, supported by the Australian Agency for International Development , became an international advocate for iodine supplementation, which is now taken for granted with iodinated table salt . This was part of the stimulus for the creation of the International Council for Control of Iodine Deficiency Disorders association, which is funded by various government, non government and community organisations including the United Nations , UNICEF , the World Health Organization , and the World Bank . It is claimed that iodine supplementation has been achieved in 70 of households worldwide by 2000. Non medical career Hetzel was Lieutenant Governor of South Australia from April 1992 May 2000. ref http www.governor.sa.gov.au html governor print.html Governor of South ...   more details



  1. Selenium deficiency

    , goitre , cretinism and habitual abortion recurrent miscarriage . ref name tp92 c3 Epidemiology ...   more details



  1. Historic Eight Documents

    Image majumdar.jpg thumb 200px right The Historic Eight Documents were authored by Charu Majumdar , and provided the ideological foundation for the Naxalite communist movement in India . The Historic Eight Documents are a set of eight monograph s authored by the India n Maoist revolutionary Charu Majumdar that outline the ideological principles on which the Naxalite militant communist movement in India was based. ref name hindustantimes2007 cite web url http www.hindustantimes.com StoryPage StoryPage.aspx?id 0b41af48 1ca9 49a1 b064 24843790d6e4&ParentID a5d3fd46 0c94 448a 99c4 c2f774a625ee&&Headline History of Naxalism title History of Naxalism publisher Hindustan Times date 2007 01 03 accessdate 2008 10 26 Snippet Communist leader Charu Majumdar wrote various articles based on Marx Lenin Mao thought during the period, which later came to be known as Historic Eight Documents and formed the basis of Naxalite movement. ref ref name ijps1990 The Indian Journal of Political Science, Volume 51 , Indian Political Science Association, 1990. Snippet ... The basic argument of these Historic Eight Documents may be summed up 1 the Indian revolution must take the path of armed struggle, 2 it should be organized on the pattern of the Chinese revolution and not of the Soviet revolution, and 3 the armed struggle in India should assume the form of Mao Tse Tung s people s war and not of Che Guevara s Guerrilla War ... ref They laid down the idea that the Government of India Indian State was a bourgeoisie bourgeois institution and that the main Indian communist parties had embraced Revisionism Marxism revisionism by agreeing to operate within the framework of the Constitution of India . ref name ijps1990 They urged a Maoism Maoist armed struggle to overthrow the Indian State. ref name damas1991 Marius Damas, Approaching Naxalbari , Radical Impression, 1991, ISBN 8185459010. Snippet ... The documents are historic in the sense that a sharp departure from parliamentary cretinism began t ...   more details



  1. Coarse facial features

    Orphan date February 2009 notability date January 2009 Coarse facial features refer to a similar change in facial features in the advanced stage of certain conditions like Cretinism , Mucopolysaccharidoses etc, where affected individuals look remarkably similar due to the coarsening of their facial features. These typical coarsening changes include short noses, flat faces and large heads. Their heads tend to be longer than normal from front to back, with a bulging forehead. This is because of the earlier than normal or premature fusion of skull bones in an affected individual. Causes Several conditions are associated with coarse facial features. ref cite web url http www.wrongdiagnosis.com symptoms coarse facial features causes.htm title Causes of Coarse facial features publisher WrongDiagnosis.com date 2010 11 18 accessdate 2011 01 03 ref Acromegaly Alpha mannosidosis type II Aspartylglycosaminuria Battaglia Neri syndrome Borjeson Syndrome Chromosome 6q deletion syndrome Coarse face hypotonia constipation Congenital hypothyroidism Dandy Walker malformation with mental retardation basal ganglia disease and seizures Dyggve Melchior Clausen Syndrome Fucosidosis type 1 Fucosidosis type II Gangliosidosis generalized GM1 type 1 Gangliosidosis GM1 type 3 GM1 gangliosidosis Goldberg syndrome Hyde Forster Mccarthy Berry syndrome Hyper IgE Hypomelanosis of Ito I cell disease Immunodeficiency due to defect in MAPBP interacting protein Infantile sialic acid storage disorder Job syndrome Mannosidosis alpha B lysosomal McCune Albright Syndrome Mental retardation X linked epilepsy progressive joint contractures typical face Mental retardation X linked Raynaud type Miescher s syndrome Morquio syndrome Morquio syndrome type A Morquio syndrome type B MPS 3 C MPS 3 D Mucolipidosis III Mucopolysaccharidosis type 2 Hunter syndrome mild form Mucopolysaccharidosis type 2 Hunter syndrome severe form Mucopolysaccharidosis type 3 Mucopolysaccharidosis type 6 Mucopolysaccharidosis type 7 Sly ...   more details



  1. Congenital hypothyroidism

    which temporarily impair thyroid function for several weeks. Citation needed date July 2009 Cretinism ... of cretinism. Persistence of severe, untreated hypothyroidism resulted in severe mental impairment ...   more details



  1. Iodine deficiency

    is permanently damaged. Cretinism main Cretinism Iodine deficiency is one of the leading cause of preventable ... for a further discussion of this controversial issue. Cretinism is a condition associated with iodine ... million suffering from deficiency, 4  million from goiter , and 0.5 million from cretinism ...   more details



  1. Belle Isle (Richmond, Virginia)

    respect, patients laboring under cretinism. They were filthy in the extreme, covered in vermin ...   more details



  1. Myxedema

    Expert subject Medicine date April 2009 Infobox disease Name Myxoedema Image Hyaluronan.png Caption Hyaluronan , an example of a mucopolysaccharide . ICD10 ICD10 E 03 9 e 00 ICD9 ICD9 244.9 DiseasesDB 6558 ICDO OMIM MedlinePlus 000353 eMedicineSubj med eMedicineTopic 1581 eMedicine mult eMedicine2 derm 347 MeshID D009230 Myxedema British English myxoedema describes a specific form of cutaneous and dermal edema secondary to increased deposition of connective tissue components like glycosaminoglycan s, hyaluronic acid , and other mucopolysaccharide s in subcutaneous tissue as seen in various forms of hypothyroidism and Graves disease . ref name Andrews cite book author James, William D. Berger, Timothy G. et al. title Andrews Diseases of the Skin clinical Dermatology publisher Saunders Elsevier location year 2006 pages isbn 0 7216 2921 0 oclc doi accessdate ref rp 535 Terminology The word originates from lang grc , taken from ancient Greek to convey mucus or slimy substance and lang grc for swelling. Hyperthyroid Myxedema typically presents in specific areas pretibial myxedema and exophthalmos and is related to high levels of Thyroid stimulating hormone TSH receptor stimulation and or inflammation mounted against the Thyroid stimulating hormone TSH receptor itself. Myxedema of the lower legs called pretibial myxedema , can occur in one to four percent of patients with Graves disease a condition that causes hyperthyroidism . ref name thedoctorsdoctor pretibial myxedema http www.thedoctorsdoctor.com diseases pretibial myxedema.htm Pretibial Myxedema , Retrieved on 2009 3 27 ref Hypothyroid Myxedema is also used to describe the clinical syndrome secondary to hypothyroidism . Symptoms can include depression, mental slowness, weakness, bradycardia, fatigue, hypothermia , alopecia , and many others see Hypothyroidism Symptoms symptoms of severe hypothyroidism . Used in this way, myxedema can be considered the adult counterpart of cretinism . ref DorlandsDict five ...   more details



  1. Tricyanoaminopropene

    learning ability in their young because of its anti thyroid hormone effects. ref Davenport JW. Cretinism ...   more details



  1. Victor Horsley

    myxedema and cretinism , which are caused by a decreased level of the thyroid hormones hypothyroidism ...   more details



  1. Teratology

    alcoholism , cretinism endemic cretinism , diabetes , folic acid deficiency , iodine deficiency , hyperthermia ...   more details



  1. Homo floresiensis

    Congenital hypothyroidism thyroid , resulting in a type of Cretinism Epidemiology endemic cretinism ...& urlVersion 0& userid 674998&md5 0d85fea5be11332d2ccd3e3eee358f6f ref Endemic cretinism hypothesis ... and LB6 suffered from Myxedema myxoedematous ME cretinism Epidemiology endemic cretinism resulting ... of cretinism. Falk challenged the premise of Oberndorf et al. Studying computer tomography ... had had cretinism, focusing on anatomical features which are typical of the disease. He found no overlap ... article by Oxnard, Obendorf and Kefford rejects Groves argument and revives the cretinism hypothesis ...   more details



  1. Thyroid-stimulating hormone

    hypothyroidism cretinism , hypothyroidism or Hashimoto s thyroiditis A TSH assay is now also the recommended ...   more details



  1. Freak the Mighty

    chases the two with his gang after Freak calls him a Cretinism cretin . With Max s lack of knowledge ...   more details




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