in experimental photodynamic therapy . Chlorin is not to be confused with the chemical element chlorine ... Category Photosynthesis Category Tetrapyrroles de Chlorin fr Chlorine io Klorino id Klorin heterolingkar ... more details
Unreferenced stub auto yes date December 2009 Tetrapyrroles are compounds containing four pyrrole rings. With the exception of corrin , the four pyrrole rings are interconnected through one carbon methine or methylene bridges, in either a linear or a cyclic fashion. Because of their ability to form metal complexes, these compounds are particularly important in biological systems. Linear tetrapyrroles bilane s , using three one carbon bridges, include Heme breakdown products e.g., bilirubin Phycobilin s found in cyanobacteria Cyclic tetrapyrroles, using four one carbon bridges, include Porphyrin s e.g., heme Chlorin s e.g., chlorophyll a Chlorophyll a Corrin s are cyclic tetrapyrroles that have replaced one of the conventional methine bridges with a direct interpyrrole bond. External links http www.chem.qmul.ac.uk iupac tetrapyrrole app1.html Tetrapyrroles Category Tetrapyrroles Biochem stub ca Tetrapirrol de Tetrapyrrole es Tetrapirrol gl Tetrapirrol nl Tetrapyrrool ja sv Tetrapyrrol ug zh ... more details
File Bacteriochlorophyll a.mol.svg thumb Bacteriochlorophyll a . R is phytyl or geranylgeranyl . Bacteriochlorophylls are photosynthetic pigment s that occur in various phototroph ic bacterium bacteria . They were discovered by Von Neil in 1932 . They are related to chlorophyll s, which are the primary pigments in plant s, alga e, and cyanobacteria . Groups that contain bacteriochlorophyll conduct photosynthesis, but do not produce oxygen . They use wavelengths of light not absorbed by plants or Cyanobacteria . Different groups contain different types of bacteriochlorophyll class wikitable width 70 Pigment Bacterial group in vivo infrared absorption maximum nm Bacteriochlorophyll a Purple bacteria Proteobacteria , Chloracidobacterium thermophilum ref Citation last1 Bryant first1 Donald A. title Candidatus Chloracidobacterium thermophilum An Aerobic Phototrophic Acidobacterium journal Science volume 317 issue 5837 pages 523 526 date 2007 07 27 year 2007 url http www.sciencemag.org cgi content abstract 317 5837 523 doi 10.1126 science.1143236 pmid 17656724 last2 Costas first2 AM last3 Maresca first3 JA last4 Chew first4 AG last5 Klatt first5 CG last6 Bateson first6 MM last7 Tallon first7 LJ last8 Hostetler first8 J last9 Nelson first9 WC author separator , display authors 1 ref 805, 830 890 Bacteriochlorophyll b Purple bacteria 835 850, 1020 1040 Bacteriochlorophyll c Green sulfur bacteria , Chloroflexi , C. thermophilum 745 755 Bacteriochlorophyll c sub s sub Chloroflexi 740 Bacteriochlorophyll d Green sulfur bacteria 705 740 Bacteriochlorophyll e Green sulfur bacteria 719 726 Bacteriochlorophyll g Heliobacteria 670, 788 Bacteriochlorophylls a , b , and g are bacteriochlorin s, with two reduced pyrrole rings B and D , and bacteriochlorophylls c , d and e are chlorin s, with one Redox reduced pyrrole ring D . References Reflist Tetrapyrroles photolithotrophic bacteria Category Photosynthetic pigments Category Tetrapyrroles cs Ba ... more details
Drugbox verifiedrevid 447519392 IUPAC name N 2 S ,3 S 7 carboxy 3 2 carboxyethyl 12 ethyl 2,8,13,18 tetramethyl 17 vinyl 2,3 dihydroporphyrin 5 yl acetyl small L small aspartic acid image Talaporfin.png Clinical data tradename Drugs.com drugs.com international talaporfin pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status Rx only routes of administration Intravenous therapy IV Pharmacokinetic data bioavailability protein bound metabolism elimination half life excretion Identifiers CAS number 110230 98 3 CAS supplemental br CAS 220201 34 3 sodium salt ATC prefix none ATC suffix ATC supplemental PubChem 5486799 DrugBank Ref drugbankcite correct drugbank DrugBank UNII Ref fdacite correct FDA UNII P4ROX5ELT2 Chemical data chemical formula C 38 H 41 N 5 O 9 molecular weight 711.76 g mol smiles CCC1 C2C C3C C C N3 C C4 C H C H C N4 C C5C C C CC C1C N2 N5 C C C C CCC O O CC O N C H CC O O C O O C O O C Talaporfin International Nonproprietary Name INN , also known as aspartyl chlorin , mono L aspartyl chlorine e6, NPe6 , or LS11 is a photosensitizer used in photodynamic therapy PDT . It absorbs red light at 664nm normally provided by a laser tuned to this wavelength. ref http journals.lww.com jto Fulltext 2006 06000 Photodynamic Therapy PDT for Lung Cancers.18.aspx Photodynamic Therapy PDT for Lung Cancers 2006 ref It was approved in Japan in 2004 for Photodynamic therapy PDT of lung cancer and marketed as Laserphyrin . ref http meeting.ascopubs.org cgi content abstract 24 18 suppl 7229 Photodynamic therapy using Laserphyrin for centrally located early stage lung cancer 2006 ref It is trademarked as Aptocine by Light Sciences Oncology. ref http www.lsoncology.com aptocine ref References reflist Chemotherapeutic agents Category Photosensitizing agen ... more details
. File Chlorin.svg thumb right This is the structure of a chlorin ring without the central Mg ... a consists of a N ring with a Mg center, side chains , and a hydrocarbon hydrocarbon tail . Chlorin ... as a chlorinchlorin ring . The chlorin ring is a heterocyclic compound derived from a pyrrole that encases ... more details
structural ring unit called chlorin is similarly complexed with magnesium instead of iron when ... a.svg 200px File Cobalamin.svg 200px small Heme group of hemoglobin small small The chlorin ... more details
. Several other heterocycles are related to porphyrins. These include corrin s, chlorin s, bacteriochlorophyll s, and Cofactor F430 corphins . Chlorin s 2,3 dihydroporphyrin are more reduced ... more details
plays a crucial role in photosynthesis . It contains a magnesium enclosed in a chlorin ring ... by other divalent ions with little loss of activity. Rather, the photon is absorbed by the chlorin ... more details
chlorin e6 NPe6 . Several photosensitizers are commercially available for clinical use, such as Allumera ... chlorin in the nuclear envelope journal Photochemistry and Photobiology volume 81 issue 6 pages 1544 ... more details
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