Biocompatibility is related to the behavior of biomaterials in various contexts. The term may refer to specific ... be sufficient to talk about the biocompatibility of a specific material. ref http www.mddionline.com article considerations biocompatibility evaluation medical devices Considerations for the Biocompatibility ... it is not adequate to describe the biocompatibility of a single material in relation to a single cell type or tissue. Sometimes one hears of biocompatibility testing that is a large battery of in vitro test ref http www.emdt.co.uk article vitro biocompatibility testing biomaterials and medical devices In Vitro Biocompatibility Testing of Biomaterials and Medical Devices , U. Muller, Medical Device ... the biocompatibility of a material, ref http www.mddionline.com article biocompatibility ... step towards the animal testing and finally clinical trial s that will determine the biocompatibility ... s or drug delivery device s. Image Annualpublbiocompatibility19702007.jpg right The word biocompatibility ..., 2008 . Five definitions of biocompatibility The ability of a material to perform with an appropriate ... http dx.doi.org 10.1016 j.biomaterials.2008.04.023 On the mechanisms of biocompatibility , David ... mdt Materials Revisiting the Definition of Biocompatibility ArticleStandard Article detail 76185 Revisiting the definition of biocompatibility , D Williams, Medical Device Technology 14 8 October 2003 ref Biocompatibility is the capability of a prosthesis implanted in the body to exist in harmony ... according to Williams Dictionary since it only defines biocompatibility as the absence of host response ..., geometry and surface treatment etc. of the device will also affect its biocompatibility. Biocompatible ... to Williams definition, this does not make any sense because biocompatibility is contextual, i.e. ... supgroups and their definitions were Biocompatibility of long term Implant medicine implanted devices The biocompatibility of a long term implantable medical device refers to the ability of the device ... more details
. Surface, corrosion and biocompatibility aspects of nitinol as an implant material. Bio Med Mater .... Layers composed of polyurethane have been used to improve biocompatibility, but have seen limited ... 1571. ref Influence of surface passivation on biocompatibility Surface passivation techniques can ... s tendency to induce clot formation, is an important factor that determines the biocompatibility ... in medical devices, due to its exceptional biocompatibility, especially in the areas of corrosion resistance ... layer are beneficial. The use of coatings has also been shown to greatly improve biocompatibility. Because ... in research aimed at enhancing biocompatibility, and in the development of new biomaterials. The development ... other biomaterials. ref Brassack, I. Bottcher, H. Hempel, U. Biocompatibility of Modified Silica Protein ... for evaluationg and determining biocompatibility. http www.devicelink.com mddi archive 00 01 017.html ... more details
Move to Commons Summary Information Description Biodegradation of melanin films in vivo. Source Biomaterials,Vol 30, Biocompatibility of biodegradable semiconducting melanin films for nerve tissue engineering , pages 3050 7 Date 2009 Author Bettinger CJ, Bruggeman JP, Misra A, Borenstein JT, Langer R Permission Elsevier other versions Licensing GFDL ... more details
Orphan date February 2009 In chemical biology , a bioorthogonal chemical reporter is a tool for tagging and visualizing biomolecule s. Prescher & Bertozzi defined bioorthogonal chemical reporters as non native, non perturbing chemical handles that can be modified in living systems through highly selective reactions with exogenously delivered probes. It has been used to enrich protein s and to conduct Proteomics proteomic analysis. In the early development of the technique, chemical motif s have to fulfill criteria of biocompatibility and selective Chemical reaction reactivity in order to qualify as bioorthogonal chemical reporters. Some combinations of proteinogenic amino acid side chains meet the criteria, as do ketone s and aldehyde s which can tag proteins and some metabolite s . Azide s and alkyne s are other examples of chemical reporters. A bioorthogonal chemical reporter must be incorporated into a biomolecule. This occurs via metabolism . The chemical reporter is linked to a substrate, which a cell biology cell can metabolize. References cite journal author Prescher, J. A. Carolyn R. Bertozzi Bertozzi, C. R. year 2005 title Chemistry in living systems journal Nature Chemical Biology volume 1 issue 1 pages 13 21 doi 10.1038 nchembio0605 13 pmid 16407987 Category Biochemistry methods biochem stub ... more details
Mergefrom biomaterial date July 2008 In surgery , a biocompatible material sometimes shortened to biomaterial is a synthetic or natural material used to replace part of a living system or to function in intimate contact with living biological tissue tissue . Biocompatible materials are intended to interface with biological systems to evaluate, treat, augment or replace any tissue, organ anatomy organ or function of the body. Biomaterials are usually viability non viable , but may also be viable. A biocompatible material is different from a biological material such as bone that is produced by a biological system . Artificial hip s, vascular stent s, artificial pacemaker s, and catheter s are all made from different biomaterials and comprise different medical devices . Biomimetic materials are not made by living organisms but have compositions and properties similar to those made by living organisms. The calcium hydroxylapatite coating found on many artificial hips is used as a bone replacement that allows for easier attachment of the Implant medicine implant to the living bone . Surface functionalization may provide a way to transform a bio inert material into a biomimetic or even bioactive material by coupling of protein layers to the surface , or coating the surface with self assembling peptide scaffolds to lend bioactivity and or cell attachment 3 D matrix. Different approaches to functionalization of biomaterials exist. Plasma processing has been successfully applied to chemically inert materials like polymer s or silicon to graft various functional group s to the surface of the implant. Polyanhydrides are polymers successfully used as a drug delivery materials. Care should be exercised in defining a biomaterial as biocompatible, since it is application specific. A biomaterial that is biocompatible or suitable for one application may not be biocompatible in another. See also Biocompatibility Biocompatible Bioengineering Biomaterial http www.biomaterials.org Socie ... more details
Infobox Company company name Micromy company logo Image Micromy.png Micromy Logo company type Private foundation location T by , Sweden key people industry Hard surface coating, Physical vapor deposition PVD products micronite subsid Production facilities also in Germany homepage http www.micromy.com www.micromy.com footnotes Micromy is a hard surface coating company based in T by , Sweden . The company specializes in applying hard coating to a wide range of substrate materials using a PVD process Physical vapor deposition . Depending on the application, different coating film materials can be produced, such as TiN Titanium nitride , TiC, TiNC grey, antracite, black , AlTiN violet, black or DLC Diamond Like Carbon . The coating is mainly used for industrial applications based on the different properties of the materials. However, the PVD process results in a finish such that many coatings are equally suitable for decorative purposes. In addition to their production, Micromy also conducts research in the T by facility. One of the applications of their research results is a new surface layer called micronite . Compared to conventional PVD coatings, micronite has outstanding tribological and corrosive properties. The coatings offered by Micromy include coatings approved for medical use under the guidelines of the United States Food and Drug Administration FDA . As such, they are suitable for sensitive applications like implants or drug manufacturing parts where biocompatibility is a requirement or where abrasive residue must be strictly controlled. Micromy offers a low temperature variant of the PVD process that makes it applicable for metal objects prone to heat deformation, or even polymer materials. Although most of the revenue is generated from contract work on customer objects or substrates, Micromy also offers a small portfolio of their own articles. Most noted are their ultra sharp scissors both surgical scissors and haircutting barber scissors . They also produ ... more details
Cleanup date May 2007 Unreferenced date October 2009 Image T rinnenverkleidung Hanf PP nova.jpg thumb upright 1.4 Interior carpeting of a cars door made by a biocomposite of hemp fibres and polyethylen A biocomposite is a material formed by a Extracellular matrix matrix resin and a reinforcement of natural fibers usually derived from plants or cellulose . With wide ranging uses from Natural environment environment friendly biodegradable composites to biomedical composites for drug gene delivery, tissue engineering applications and cosmetic orthodontics . They often mimic the structures of the living materials involved in the process in addition to the strengthening properties of the matrix that was used but still providing biocompatibility, e.g. in creating scaffolds in bone tissue engineering. Those markets are significantly rising, mainly because of the increase in oil price, and recycling and environment necessities. Biocomposites are characterised by the fact that the petrochemical resin is replaced by a vegetable or animal resin, and or the bolsters fiberglass , carbon fibre or talc are replaced by natural fibre wood fibres, hemp , flax , sisal , jute ... In biomaterials, it is important that each constituent of the composite be biocompatible. Moreover, the interface between constituents should not be degraded by the body environment. Normally, Bio composite material can be classify in to three groups Particulate Composites Fibrous Composites Porous Materials External links http www.composite agency.com messages 3958.html Discussion on physical chemical properties of biocomposites http daifa.fr index.php?Page 71 Example and photo of a sandwich biocomposite manufactured with a wood fabric hemp matrix and 20 PU resin The resulting material combines high resistance and low weight, with bending modulus of 9000MPa and a density 0,5 T m3. http www.kareline.com www.kareline.com thermoplastic injection moulded biocomposites Category Composite materials material stub de ... more details
Onesource date December 2007 Biotextiles are structures composed of textile fibers designed for use in specific biological environments where their performance depends on biocompatibility and biostability with cell biology cell s and biological fluids . Biotextiles include implantible devices such as surgical suture s, hernia repair fabrics, artery arterial Medical grafting grafts , artificial skin and parts of artificial heart s. They were first created 30 years ago by Dr. Martin W. King, a professor in North Carolina State University s College of Textiles http www.tx.ncsu.edu faculty center directory detail.cfm?id 63 . Medical textiles are a broader group which also includes bandages, wound dressings, hospital linen, preventive clothing etc. Antiseptic biotextiles are textiles used in fighting against cutaneous bacteria l proliferation. Zeolite and triclosan are at the present time the most used molecules. This original property allows to fightinhibits the development of odours or bacterial proliferation in the diabetic foot. New developments In the new paradigm of tissue engineering , professionals are trying to develop new textiles so that the body can form new tissue around these devices so it s not relying solely on synthetic foreign implanted material. Graduate student Jessica Gluck has demonstrated that viable and functioning liver cells can be grown on textile scaffolds http www.physorg.com news96302396.html . See also Technical textiles External links http www.ncsu.edu research results vol5 6.html website NC State s College of Textiles on biotextiles Category Bioengineering Category Textiles ... more details
profession and the public. Projects include material characterization and properties, biocompatibility ... materials. Participation in standardization work for dental products and for biocompatibility in general ... ISO TC 194 Biocompatibility of medical devices CEN TC 55 Dentistry, and CEN TC 206 Biocompatibility ... more details
Orphan date January 2011 Italic title Infobox journal title Journal of Materials Science Materials in Medicine cover File Msmed cover.jpg editor Serena M. Best, Josep A. Planell discipline Materials science abbreviation J. Mater. Sci. Mater. Med. publisher Springer Science Business Media country frequency Monthly history 1990 present openaccess impact 1.955 impact year 2009 website http www.springer.com journal 10856 link1 http www.springerlink.com content 0957 4530 link1 name Online access link2 link2 name JSTOR OCLC 21929562 LCCN 91642022 CODEN JSMMEL ISSN 0957 4530 eISSN 1573 4838 The Journal of Materials Science Materials in Medicine is a peer review peer reviewed scientific journal published by Springer Science Business Media . It is a companion to the Journal of Materials Science focusing specifically on materials in medicine and dentistry. The journal is an offshoot of the Journal of Materials Science . It is the official journal of the European Society for Biomaterials . The founding editor in chief was William Bonfield the current editors are Serena M. Best Cambridge Centre for Medical Materials and Josep A. Planell Polytechnic University of Catalonia . According to the Journal Citation Reports , the Journal of Materials Science Materials in Medicine has a 2009 impact factor of 1.955. ref Citation title Journal Citation Reports year 2010 accessdate 2010 10 13 ref Scope The journal s content focusses on the development of synthetic and natural materials for orthopaedic, maxillofacial, cardiovascular, neurological, ophthalmic and dental applications. Further, biocompatibility studies, nanomedicine , studies on regenerative medicine , computer modelling , and other advanced experimental methodologies are included. ref cite web url http www.springer.com materials structural 26 biomaterials journal 10856?detailsPage description title Journal of Materials Science Materials in Medicine About this journal accessdate 2009 10 09 ref References reflist External links ... more details
Medical grade silicones are silicone s tested for biocompatibility and are appropriate to be used for medical applications. In the United States, the Food and Drug Administration FDA regulates materials Implant medicine implant ed into the body. ref http www.fda.gov MedicalDevices DeviceRegulationandGuidance Overview ClassifyYourDevice default.htm FDA Device Regulation and Guidance ref Medical grade silicones are generally grouped into three categories non implantable, short term implantable, and long term implantable. Materials approved as USP ref http www.usp.org referenceStandards USP Reference Standards ref Class V and VI can be considered medical grade. Most medical grade silicones are at least Class VI certified. Silicone suppliers and some silicone prototyping companies provide guidelines for material use ref http www.albright1.com silicone design manual.php Silicone Design Manual ref . History In 1954, McDougall reported that various tissue cultures taken from warm blooded animals known to be extraordinarily sensitive to foreign influences showed no deviation from usual growth patterns. Uses Tubing Drains Feeding tubes Catheters Implants for long and short term use Seals and gaskets Scar Treatment Silicone Sheets FDA Class 1 Medical Device and gels. Condoms Menstrual cups http www.mooncup.co.uk Sex toys See also silicone United States Pharmacopeia U.S. Food and Drug Administration Silicone rubber Polymers Plastics engineering References references Category Silicones Category Medical technology Category Elastomers Category Biomaterials Category Silicone rubber medical equipment stub ... more details
X Robert A. Freitas Jr. , Nanomedicine, Vol. IIA Biocompatibility Landes Bioscience, 2003 ISBN 1 57059 ... Bioscience, 2004 ISBN 1 57059 690 5 Robert A. Freitas Jr. , Nanomedicine Biocompatibility S Karger ... more details
by improving the biocompatibility of the electrode itself, thus reducing the tissue s perception ... response is focused on improved biocompatibility . It is difficult to effectively evaluate progress towards improved electrode biocompatibility because of the variety of research in this field. Improving biocompatibility of recording electrodes This section loosely categorizes different approaches to improving biocompatibility seen in the literature. Descriptions of the research are limited ... ludwig Protein functionalization Another body of research dedicated to improving the biocompatibility ... Neurophysiology, 2005. 116 9 p. 2240 2250. note vince Vince, V., et al., Biocompatibility of platinum ... modification of ceramic based microelectrodes to enhance biocompatibility for a direct brain machine ... more details
research in the area of Biocompatibility the ability of a material to interface within ... for biocompatibility. In 1984, Professor Chapman founded Biocompatibles, which patented PC Technology ... more details
peacock date October 2010 Introduction Traditional pursuits in organic electronics have demonstrated tremendous versatility in a wide range of applications including consumer electronics, photovoltaics, and biotechnology. However, the interface of biomolecules and organic semiconductors has recently explored the potential use of natural and synthetic polymers as structural components of electronic devices. The fabrication of electronically active system using biomaterials based components has the potential to realize a large set of unique devices including environmentally biodegradable systems and bioresorbable temporary medical devices ref cite journal journal Appl. Phys. Lett. volume 95, 133701 date 2009 title Silicon electronics on silk as a path to bioresorbable, implantable devices author Kim DH, Kim YS, Amsden J, Panilaitis B, Kaplan DL, Omenetto FG, Zakin MR, and Rogers JA ref Natural organic semiconductors There are abundant opportunities in the convergence of biodegradable materials and organic semiconductors to produce electronic systems with unique overall material profiles. Melanins are a unique class of organic material that bridges organic semiconductors and biomaterials. Melanins have demonstrated unique switching properties ref name source1 cite journal author McGinness J, Corry P, Proctor P title Amorphous Semiconductor Switching in Melanins journal Science year 1974 volume 183 issue 4127 pages 853 5 ref as well as biocompatibility File Figure1 Melanin.jpg thumb alt Biodegradation of melanin films in vivo. Courtesy of Christopher Bettinger. Figure 1. Biodegradation of melanin films in vivo. Reprinted from Biomaterials,Vol 30, Bettinger CJ, Bruggeman JP, Misra A, Borenstein JT, Langer R. Biocompatibility of biodegradable semiconducting melanin films for nerve tissue engineering , pages 3050 7, copyright 2009, with permission from Elsevier. . ref name source2 cite journal author Bettinger CJ, Bruggeman JP, Isra A, Borenstein JT, Langer R title Biocomp ... more details
is composed of slice of parallel circuits. Essential Requirements Biocompatibility Since the prosthesis will be permanently implanted inside the brain, long term biocompatibility is required. Also we ... are implanted inside the brain, long term biocompatibility aside, the power supply will require ... more details
This page is about types of dental restorative materials. For dental fillings see dental restorations Dental restorative materials are specially fabricated materials, designed for use as dental restorations fillings , which are used to restore tooth structure loss, usually resulting from but not limited to dental caries dental cavities . There are many challenges for the physical properties of the ideal dental restorative material. Restorative material development The goal of research and development is to develop the ideal restorative material. The ideal restorative material would be identical to natural tooth structure, in strength adherence and appearance. The properties of an ideal filling material can be divided into four categories physical properties, biocompatibility , aesthetics and application. Physical properties Requisite physical properties include low thermal conductivity and expansion, resistance to different categories of forces and wear like attrition and abrasion and resistance to chemical erosion. There must also be good bonding strength to the tooth. Everyday masticatory forces and conditions must be withstood without fatiguing. Biocompatibility Biocompatibility refers to how well the material coexists with the biological equilibrium of the tooth and body systems. Since fillings are in close contact with mucosa, tooth, and pulp, biocompatibility is very important. Common problems with some of the current dental materials include chemical leakage from the material, pulpal irritation and less commonly allergy. Some of the byproducts of the chemical reactions during different stages of material hardening need to be considered. Aesthetics Filling materials ideally would match the surrounding tooth structure in shade, translucency, and texture. Application Dental operators require materials that are easy to manipulate and shape, where the chemistry of any reactions that need to occur are predictable or controllable. Direct restorative materials The ch ... more details
Unreferenced date December 2009 Pre clinical development is a stage of research that begins before clinical trial s testing in humans can begin, and during which important feasibility, iterative testing and safety also known as Good Laboratory Practice or GLP data is collected. The main goals of pre clinical studies also named preclinical studies and nonclinical studies are to determine a product s ultimate safety profile. Products may include new or iterated or like kind medical devices, drugs, gene therapy solutions, etc. Each class of product may undergo different types of preclinical research. For instance, drugs may undergo pharmacodynamics PD , pharmacokinetics PK , ADME , and toxicity testing through in vivo animal testing . This data allows researchers to Allometry allometrically estimate a safe starting dose of the drug for clinical trial s in humans. Medical devices that do not have drug attached will not undergo these additional tests and may go directly to GLP testing for safety of the device and its components. Some medical devices will also undergo biocompatibility testing which helps to show whether a component of the device or all components are sustainable in a living model. Most pre clinical studies must adhere to Good Laboratory Practice s GLP in International Conference on Harmonisation of Technical Requirements for Registration of Pharmaceuticals for Human Use ICH Guidelines to be acceptable for submission to regulatory agencies such as the Food & Drug Administration in the United States. Typically, both in vitro and in vivo tests will be performed. Studies of a drug s toxicity include which organs are targeted by that drug, as well as if there are any long term carcinogenic effects or toxic effects on mammalian reproduction . The information collected from these studies is vital so that safe human testing can begin. Typically, in drug development studies animal testing involves two species. The most commonly used models are Murinae murine and B ... more details
Unreferenced stub auto yes date December 2009 The ISO 10993 set entails a series of standards for evaluating the biocompatibility of a medical device prior to a clinical study Citation needed date June 2009 . These documents were preceded by the Tripartite agreement and is a part of the harmonisation of the safe use evaluation of medical devices Citation needed date June 2009 . List of the standards in the 10993 series ISO 10993 1 2009 Biological evaluation of medical devices Part 1 Evaluation and testing ISO 10993 2 2006 Biological evaluation of medical devices Part 2 Animal welfare requirements ISO 10993 3 2003 Biological evaluation of medical devices Part 3 Tests for genotoxicity, carcinogenicity and reproductive toxicity ISO 10993 4 2002 Amd 1 2006 Biological evaluation of medical devices Part 4 Selection of tests for interactions with blood ISO 10993 5 2009 Biological evaluation of medical devices Part 5 Tests for in vitro cytotoxicity ISO 10993 6 2007 Biological evaluation of medical devices Part 6 Tests for local effects after implantation ISO 10993 7 2008 Biological evaluation of medical devices Part 7 Ethylene oxide sterilization residuals ISO 10993 8 2001 Biological evaluation of medical devices Part 8 Selection of reference materials ISO 10993 9 1999 Biological evaluation of medical devices Part 9 Framework for identification and quantification of potential degradation products ISO 10993 10 2010 Biological evaluation of medical devices Part 10 Tests for irritation and delayed type hypersensitivity ISO 10993 11 2006 Biological evaluation of medical devices Part 11 Tests for systemic toxicity ISO 10993 12 2007 Biological evaluation of medical devices Part 12 Sample preparation and reference materials available in English only ISO 10993 13 1998 Biological evaluation of medical devices Part 13 Identification and quantification of degradation products from polymeric medical devices ISO 10993 14 2001 Biological evaluation of medical devices Part 14 Identificati ... more details
Image PLGA.svg thumb Structure of poly lactic co glycolic acid . x number of units of lactic acid y number of units of glycolic acid . For the tumour see polymorphous low grade adenocarcinoma PLGA or poly lactic co glycolic acid is a copolymer which is used in a host of Food and Drug Administration FDA approved therapeutic devices, owing to its Biodegradation biodegradability and biocompatibility . PLGA is synthesized by means of random ring opening co polymerization of two different monomer s, the cyclic dimers 1,4 dioxane 2,5 diones of glycolic acid and lactic acid . Common catalysts used in the preparation of this polymer include tin II 2 Ethylhexanoic acid 2 ethylhexanoate , tin II alkoxide s, or aluminum isopropoxide . During polymerization, successive monomeric units of glycolic or lactic acid are linked together in PLGA by ester linkages, thus yielding a linear, aliphatic polyester as a product. ref cite journal author Astete, C. E. and Sabliov, C. M. title Synthesis and characterization of PLGA nanoparticles year 2006 journal Journal of Biomaterials Science Polymer Edition volume 17 issue 3 pages 247 289 doi 10.1163 156856206775997322 pmid 16689015 ref Depending on the ratio of lactide to glycolide used for the polymerization, different forms of PLGA can be obtained these are usually identified in regard to the monomers ratio used e.g. PLGA 75 25 identifies a copolymer whose composition is 75 lactic acid and 25 glycolic acid . All PLGAs are Amorphous solid amorphous rather than crystallinity crystalline and show a glass transition temperature in the range of 40 60 C. Unlike the homopolymer s of lactic acid polylactide and glycolic acid polyglycolide which show poor solubilities, PLGA can be dissolved by a wide range of common solvent s, including chlorine chlorinated solvents, tetrahydrofuran , acetone or ethyl acetate . PLGA degrades by hydrolysis of its ester linkages in the presence of water molecule water . It has been shown that the time required for de ... more details
Su 8 redirects here. For the Soviet ground attack aircraft, see Sukhoi Su 8 Image SU 8 photoresist.png right thumb 250px SU 8 molecule SMILES structure CC C c8ccc OCC 13OC 13 cc8 c1cc Cc2cc C C c9ccc OCC 14OC 14 cc9 C cc Cc4cc C C c 10ccc OCC 15OC 15 cc 10 C cc Cc6cc C C c 11ccc OCC 16OC 16 cc 11 C ccc6OCC7OC7 c4OCC5OC5 c2OCC3OC3 c OCC 12OC 12 cc1 Can anybody find its corresponding CAS number? SU 8 is a commonly used epoxy based negative photoresist . It is a very viscous polymer that can be spin coating spun or spread over a thickness ranging from 0.1 Micrometre micrometer Ref? up to 2 millimeters and still be processed with standard contact lithography . It can be used to pattern high aspect ratio 20 structures. ref name aspect ratio Liu, J. Cai, B. Zhu, J. Ding, G. Zhao, X. Yang, C. Chen, D. http dx.doi.org 10.1007 s00542 002 0242 2 Process research of high aspect ratio microstructure using SU 8 resist Microsystem Technologies 2004, V10, 4 , 265. ref Its maximum absorption electromagnetic radiation absorption is for ultraviolet light with a wavelength of 365 nm. When exposed, SU 8 s long molecular chains cross link causing the solidification of the material. SU 8 was originally developed as a photoresist for microelectronics industry, to provide a high resolution mask for fabrication of semiconductor devices. It is now mainly used in the fabrication of microfluidics mainly via soft lithography , but also with other imprinting techniques such as nanoimprint lithography ref name imprint lithography Jesse Greener, Wei Li, Judy Ren, Dan Voicu, Viktoriya Pakharenko, Tian Tang and Eugenia Kumacheva http www.rsc.org Publishing Journals LC article.asp?doi b918834g Rapid, cost efficient fabrication of microfluidic reactors in thermoplastic polymers by combining photolithography and hot embossing Lab Chip, 2010, DOI 10.1039 b918834g. ref and microelectromechanical systems parts. It is also one of the most Biocompatibility biocompatible materials known and is often used in ... more details
Leigh Canham is a British scientist who has pioneered the optoelectronic and biomedical applications of porous silicon . Leigh Canham graduated from University College London in 1979 with a BSc in Physics and completed his PhD at King s College London in 1983. His early work in this area took place at the Royal Signals and Radar Establishment in Malvern, Worcestershire . Canham and his colleagues showed that electrochemically etched silicon could be made porous. This porous material could emit visible light when a current was passed through it electroluminescence . Later the group demonstrated the biocompatibility of porous silicon. Canham now works as Chief Scientific Officer of psiMedica part of psivida pSiVida . According to the pSiVida web site, Canham is the most cited author on porous silicon. In a study of most cited physicists up to 1997 Canham ranked at 771. Bibliography Selected papers Porous silicon based scaffolds for tissue engineering and other biomedical applications, Jeffery L. Coffer, Melanie A. Whitehead, Dattatri K. Nagesha, Priyabrata Mukherjee, Giridhar Akkaraju, Mihaela Totolici, Roghieh S. Saffie, Leigh T. Canham, physica status solidi a Vol. 202, Issue 8 , Pages 1451 1455 Gaining light from silicon, Leigh Canham, Nature vol. 408, pp. 411 412 2000 doi 10.1038 35044156 Progress towards silicon optoelectronics using porous silicon technology, L. T. Canham, T. I. Cox, A. Loni and A. J. Simons, Applied Surface Science, Volume 102, Pages 436 441 1996 Porous silicon multilayer optical waveguides, A. Loni, L. T. Canham, M. G. Berger, R. Arens Fischer, H. Munder, H. Luth, H. F. Arrand and T. M. Benson, Thin Solid Films, Vol. 276, Issues 1 2, pages 143 146 1996 The origin of efficient luminescence in highly porous silicon, K. J. Nash, P. D. J. Calcott, L. T. Canham, M. J. Kane and D. Brumhead, J. of Luminescence, Volumes 60 61, Pages 297 301 1994 Electronic quality of vapour phase epitaxial Si grown at reduced temperature, W. Y. Leong, L. T. Canha ... more details
Breast implants Biomaterials must be compatible with the body, and there are often issues of biocompatibility ... Textbook Compatibility Biocompatibility is related to the behavior of biomaterials in various environments ... be sufficient to talk about the biocompatibility of a specific material. ref http www.devicelink.com mddi archive 01 05 008.html Considerations for the Biocompatibility Evaluation of Medical Devices ... more details
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