- Basiliximab
products name simulect.jsp Novartis product page for Simulect basiliximab for injection . Retrieved ... an immune response against the transplant. Like the similar drug daclizumab , basiliximab ... treated with Basiliximab as an alternative therapy to Cyclosporine , with a dose of 20mg every 4 ... stub antineoplastic drug stub de Basiliximab es Basiliximab it Basiliximab pl Bazyliksymab ru ... more details
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- ATC code L04
ATC codes lead L 04 Immunosuppressants anchor L04A L04A Immunosuppressants anchor L04AA L04AA Selective immunosuppressants L04AA02 Muromonab CD3 L04AA03 Antilymphocyte immunoglobulin horse L04AA04 Antithymocyte immunoglobulin rabbit L04AA06 Mycophenolic acid L04AA10 Sirolimus L04AA13 Leflunomide L04AA15 Alefacept L04AA18 Everolimus L04AA19 Gusperimus L04AA21 Efalizumab L04AA22 Abetimus L04AA23 Natalizumab L04AA24 Abatacept L04AA25 Eculizumab L04AA26 Belimumab L04AA27 Fingolimod L04AA28 Belatacept anchor L04AB L04AB Tumor necrosis factor alpha TNF inhibitors L04AB01 Etanercept L04AB02 Infliximab L04AB03 Afelimomab L04AB04 Adalimumab L04AB05 Certolizumab pegol L04AB06 Golimumab anchor L04AC L04AC Interleukin inhibitors L04AC01 Daclizumab L04AC02 Basiliximab L04AC03 Anakinra L04AC04 Rilonacept L04AC05 Ustekinumab L04AC06 Mepolizumab L04AC07 Tocilizumab L04AC08 Canakinumab L04AC09 Briakinumab L04AC10 Secukinumab anchor L04AD L04AD Calcineurin inhibitors L04AD01 Ciclosporin L04AD02 Tacrolimus L04AD03 Voclosporin anchor L04AX L04AX Other immunosuppressants L04AX01 Azathioprine L04AX02 Thalidomide L04AX03 Methotrexate L04AX04 Lenalidomide L04AX05 Pirfenidone References Reflist Immunosuppressants Category ATC codes L04 Category Immunosuppressants ca Codi ATC L04 cs ATC k d L04 es Anexo C digo ATC L04 ko ATC L04 hu ATC L04 Immunszuppressz v szerek pl ATC L04 ro Cod ATC L04 sv ATC kod L04 Immunsuppressiva medel th ATC L04 ... more details
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- List of drugs: Si
List of drugs S Si si sia sil siagoside International Nonproprietary Name INN Sibelium sibenadet United States Adopted Name USAN Siblin sibopirdine International Nonproprietary Name INN sibrafiban International Nonproprietary Name INN sibrotuzumab International Nonproprietary Name INN sibutramine International Nonproprietary Name INN siccanin International Nonproprietary Name INN sifalimumab United States Adopted Name USAN , International Nonproprietary Name INN sifaprazine International Nonproprietary Name INN sifilcon A United States Adopted Name USAN siguazodan International Nonproprietary Name INN Silafed Silain silandrone International Nonproprietary Name INN Sildaflo Sildec sildenafil International Nonproprietary Name INN Silexin silibinin International Nonproprietary Name INN silicristin International Nonproprietary Name INN silidianin International Nonproprietary Name INN silmitasertib International Nonproprietary Name INN silperisone International Nonproprietary Name INN Silphen siltenzepine International Nonproprietary Name INN silteplase International Nonproprietary Name INN Siltussin CF siltuximab United States Adopted Name USAN Silvadene sim sit simaldrate International Nonproprietary Name INN simenepag United States Adopted Name USAN , International Nonproprietary Name INN simendan International Nonproprietary Name INN simeprevir International Nonproprietary Name INN simetride International Nonproprietary Name INN simfibrate International Nonproprietary Name INN simoctocog alfa International Nonproprietary Name INN simotaxel United States Adopted Name USAN Golimumab Simponi simtrazene International Nonproprietary Name INN Basiliximab Simulect simvastatin International Nonproprietary Name INN sinapultide International Nonproprietary Name INN sincalide International Nonproprietary Name INN Sine Aid IB sinecatechins United States Adopted Name USAN sinefungin International Nonproprietary Name INN Sinemet Sinequan Singulair sinitrodil International Nonpropr ... more details
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- List of drugs: Ba
Name INN Basaljel Basifungin International Nonproprietary Name INN Basiliximab International ... more details
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- Daclizumab
formation of antibodies against the transplant. Like the similar drug basiliximab , daclizumab reduces ... more details
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- Anti-thymocyte globulin
antibodies such as basiliximab and daclizumab are increasingly being used in place of ATG as an induction ... more details
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- Muromonab-CD3
accessdate 3 January 2010 ref Unlike the monoclonal antibodies basiliximab and daclizumab , it is not approved ... more details
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- TOL101
Orphan date September 2010 Drugbox verifiedrevid 451563029 Monoclonal antibody data type mab mab type mab source o target T cell receptor T Cell Receptor Clinical data tradename legal status Investigational New Drug Renal Transplantation routes of administration Intravenous Chemical data TOL101 , is a murine monoclonal antibody specific for the human T cell receptor . In 2010 it was an Investigational New Drug under development by Tolera Therapeutics , Inc. Clinical progress TOL101 is a clinical stage investigational drug. The safety and efficacy of TOL101 is currently the focus of a phase 2 clinical trial in renal transplant patients. http www.clinicaltrials.gov ct2 results?term tol101 Orphan drug status TOL101 was granted orphan drug status http www.fda.gov ForIndustry DevelopingProductsforRareDiseasesConditions HowtoapplyforOrphanProductDesignation default.htm by the Food and Drug Administration United States U.S. Food and Drug Administration for the treatment of recent onset immune mediated Type 1 diabetes and for prophylaxis of acute rejection of solid organ Organ transplantation transplant ation. Rationale for development There are numerous agents currently under investigation that are capable of modulating T cells. Currently used agents include anti thymocyte globulin ATG and alemtuzumab , which not only affect T cells, but are also capable of modulating many other aspects of the immune system, often resulting in long term broad spectrum immune suppression. ref Cite journal doi 10.1056 NEJMoa060068 author Brennan, DC, Daller JA, Lake KD, Cibrik D, Del Castillo D year 2006 title Rabbit antithymocyte globulin versus basiliximab in renal transplantation journal N Engl J Med volume 355 issue 19 pages 1967 77 pmid 17093248 ref ref Cite journal pmid 17410187 doi 10.1038 sj.leu.2404683 author Mohty M year 2007 title Mechanisms of action of antithymocyte globulin T cell depletion and beyond journal Leukemia journal Leukemia volume 21 issue 7 pages 1387 94 ref A ... more details
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- Monoclonal antibody therapy
4 ref Basiliximab and daclizumab inhibit interleukin 2 IL 2 on activated T cells and thereby help ... auto immune disorders Alemtuzumab Campath 2001 humanized CD52 Chronic lymphocytic leukemia Basiliximab ... more details
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- Monoclonal antibodies
by their ability to bind to and inhibit TNF . ref name Rang Basiliximab and daclizumab inhibit ... infliximab, basiliximab, abciximab, daclizumab, palivusamab, gemtuzumab, alemtuzumab and rituximab ... inhibits TNF human basiliximab ref name Rang Acute organ rejection rejection of kidney transplants ... more details
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- Transplant rejection
patient use only. Antibody drugs Monoclonal anti IL 2R receptor antibodies Basiliximab Daclizumab ... more details
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- Humanized antibody
a xi stem. Examples of chimeric antibodies approved for human therapy include abciximab ReoPro , basiliximab ... more details
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- Tacrolimus
corticosteroids steroids , mycophenolate and IL 2 receptor basiliximab inhibitors . Dosages are titrated ... more details
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- Immunosuppressive drug
, leading to the presentation of two chimeric mouse human anti Tac antibodies in the year 1998 basiliximab ... more details
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- Nomenclature of monoclonal antibodies
not indicate the foreign species used for production. Thus, the human mouse chimeric antibody basiliximab ... more details
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- IL-2 receptor
. Clinical implications Drugs that inhibit IL 2 receptors, such as basiliximab and daclizumab are used ... more details
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- List of monoclonal antibodies
Basiliximab Simulect mab chimeric CD25 chain of interleukin 2 IL 2 receptor prevention of organ ... more details
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- Mohamed Ghonim
A. Sobh and Mohamed A. Ghoneim. Basiliximab induction therapy for live donor kidney transplantation ... more details
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