PBB geneid 553 Vasopressin V1b receptor V1bR also known as vasopressin 3 receptor VPR3 or antidiuretic hormone receptor 1b is a protein that in humans is encoded by the AVPR1B argininevasopressin receptor 1B gene . V1bR acts as Vasopressin receptor receptor for argininevasopressin . AVPR1B belongs ... and the control of water, glucose, and salts in the blood. Argininevasopressin has four receptors ... Duijn C, Deboutte D, Van Broeckhoven C, Claes S title A major SNP haplotype of the argininevasopressin ... region 1q32 and is a member of the vasopressin oxytocin family subfamily. ref name urlanti ArginineVasopressin Receptor 1B AVPR1B antibody ABIN122463 cite web url http www.antibodies online.com antibody 122463 anti ArginineVasopressin Receptor 1B AVPR1B title anti ArginineVasopressin Receptor ... GB, K rteszi M, L szl FA title Evidence that the effects of arginine 8 vasopressin AVP on pituitary ... has several influences and regulatory actions. Argininevasopressin influences several symptoms ... on ACTH release. ref name urlanti ArginineVasopressin Receptor 1B AVPR1B antibody ABIN122463 This interaction takes place as ArginineVasopressin works with corticotropin releasing hormone to stimulate ... argininevasopressin 1b receptor and glucocorticoid receptor gene variants and HPA axis responses ... pmid14624682 cite journal author Holmes CL, Landry DW, Granton JT title Science review Vasopressin and the cardiovascular ... AVPR1B was initially described as a novel vasopressin receptor located in the anterior pituitary , where ..., Schoots O, Lolait SJ, Burbach JP title Immunohistochemical localization of the vasopressin V sub 1b ... effects of vasopressin journal Endocrinology volume 142 issue 4 pages 1659 68 year 2001 pmid 11250948 ... SR, Palkovits M title The Vasopressin 1b Receptor is Prominent in the Hippocampal Area CA2 Where ... SR, Caldwell HK, Christiansen M, Young WS title Disruption of the Vasopressin 1b Receptor Gene Impairs ... is reduced in vasopressin 1b receptor null mice despite normal performance in an olfactory discrimination ... more details
PBB geneid 554 Argininevasopressin receptor 2 officially abbreviated AVPR2 is a protein that acts as Vasopressin receptor receptor for argininevasopressin . ref name pmid1324225 cite journal author van .... In the kidney, AVPR2 s primary property is to respond to argininevasopressin by stimulating ... antidiuretic hormone SIADH and cirrhosis . Interactions Argininevasopressin receptor 2 has been ... LA, van Oost BA title Colocalization of the gene for nephrogenic diabetes insipidus DIR and the vasopressin ... See Vasopressin receptor antagonist Vasopressin receptor antagonist s that are selective for the V2 ... citations cite journal author Birnbaumer M title The V2 vasopressin receptor mutations and fluid ... with mutations of vasopressin V2 receptors and aquaporin 2 journal Nippon Rinsho volume 60 issue ... A, Shoham M title Molecular pharmacology and modeling of vasopressin receptors journal Prog. Brain Res ... author Robben JH, Knoers NV, Deen PM title Cell biological aspects of the vasopressin type 2 receptor ... journal author Pan Y, Metzenberg A, Das S, et al. title Mutations in the V2 vasopressin receptor gene ... JC, Verdijk M, et al. title Mutations in the vasopressin type 2 receptor gene AVPR2 associated .... title Colocalization of the gene for nephrogenic diabetes insipidus DIR and the vasopressin type 2 ... author Lolait SJ, O Carroll AM, McBride OW, et al. title Cloning and characterization of a vasopressin ... of vasopressin type 2 receptor in patients with X linked nephrogenic diabetes insipidus journal ... cite journal author Fa V, Ventruto ML, Loche S, et al. title Mutations in the vasopressin V2 receptor ... insipidus mutation of the vasopressin receptor reduces cell surface expression, affinity for ligand ... A, et al. title Novel mutations in the V2 vasopressin receptor gene of patients with X linked nephrogenic ... novel mutations in the vasopressin V2 receptor gene in patients with congenital nephrogenic diabetes ... Yuasa H, Ito M, Oiso Y, et al. title Novel mutations in the V2 vasopressin receptor gene in two ... more details
PBB geneid 552 Argininevasopressin receptor 1A officially called AVPR1A is one of the three major receptor types for VasopressinargininevasopressinArgininevasopressin receptor 1B AVPR1B and Argininevasopressin receptor 2 AVPR2 being the others , and is present throughout the brain, as well as in the periphery ... url h pmc 2292122 ref Argininevasopressin receptor 1A is also known as V1a vasopressin receptor antidiuretic hormone receptor 1A SCCL vasopressin subtype 1a receptor V1 vascular vasopressin receptor AVPR1A vascular hepatic type argininevasopressin receptor Structure and function Human ... game associated with length of the argininevasopressin 1a receptor RS3 promoter region and correlation ..., Badner JA, Cook EH Jr title Are the argininevasopressin V1a receptor microsatellites related to hypersexuality ... S, Shulman C, Nemanov L, Dina C, Ebstein RP title Association between the argininevasopressin ... genetic studies of the argininevasopressin 1a receptor AVPR1a and the oxytocin receptor OXTR ... of argininevasopressin receptor 1A AVPR1A polymorphisms in autism. journal Mol. Psychiatry volume ... protein box yes update summary no update citations yes DEFAULTSORT ArginineVasopressin Receptor 1a ... HK, Lee HJ, Macbeth AH, Young WS title Vasopressin behavioral roles of an original neuropeptide ... cloning, sequencing, and functional expression of a cDNA encoding the human V1a vasopressin receptor ... at position 54 E54 and the arginine residue at position 46 R46 are critical for binding with AVP ... title The N terminal juxtamembrane segment of the V1a vasopressin receptor provides two independent ... author Terrillon S, Barberis C, Bouvier M title Heterodimerization of V1a and V2 vasopressin receptors ... have long lasting sexually dimorphic effects on vasopressin receptors journal Neuroscience volume ... cite journal author Nair HP, Young LJ title Vasopressin and pair bond formation genes to brain to behavior ... in vasopressin V1a receptor knockout mice journal Neuropsychopharmacology volume 3 issue 3 pages ... more details
Merge from Vasopressin receptor antagonist discuss Talk Vasopressin Merger proposal for Vasopressin receptor antagonist date May 2011 PBB geneid 551 Argininevasopressin AVP , also known as vasopressin ... T title Angiotensin II stimulated secretion of argininevasopressin is inhibited by atrial natriuretic ... wikitable Type Second messenger system Locations Actions Argininevasopressin receptor 1A AVPR1A ... ref Argininevasopressin receptor 1B AVPR1B or AVPR3 Phosphatidylinositol calcium Pituitary ... doi 10.1016 j.yhbeh.2004.07.004 ref Argininevasopressin receptor 2 AVPR2 Adenylate cyclase Cyclic ... structure of the argipressin indicating that this compound is of the vasopressin family with an arginine ... . The amino acid sequence of argininevasopressin is cysteine Cys tyrosine Tyr Phenylalanine Phe glutamine ... forming a sulfur bridge . Lysine vasopressin has a lysine in place of the arginine. The structure ... and Vasopressin Genetics and Behavioral Implications chapterurl http refworks.springer.com mrw fileadmin ... ref Vasopressin increases water permeability of kidney collecting duct by inducing translocation ... MA title Vasopressin increases water permeability of kidney collecting duct by inducing translocation ... issue 4 pages 1013 7 year 1995 month February pmid 7532304 pmc 42627 doi ref Vasopressin is a peptide ... of vasopressin receptor AVPr1a in prairie vole ventral forebrain regions have been shown to facilitate .... ref name Young2004 cite journal author Lim MM, Young LJ title Vasopressin dependent neural ... similar substance, lysine vasopressin LVP or lypressin , has the same function in pig s and is often used in human therapy. Kidney Vasopressin has two effects by which it contributes to increased urine ... of aquaporin 2 water channels by exocytosis of intracellular vesicles, recycling endosomes. Vasopressin ... from intracellular stores. Vasopressin, acting through cAMP, also increases transcription of the aquaporin ... collecting duct . Cardiovascular system Vasopressin increases peripheral vascular resistance vasoconstriction ... more details
Merge from Arginine pyroglutamate date April 2010 chembox Verifiedfields changed verifiedrevid 457140847 Name small L small Arginine ImageFileL1 L Arginin L Arginine.svg ImageSizeL1 200px ImageFileR1 L arginine 3D hztl.png ImageSizeR1 120px IUPACName S 2 Amino 5 guanidinopentanoic acid OtherNames Arginine ... BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition Arginine abbreviated ... that codify for arginine during protein synthesis. In mammals, arginine is classified as a semiessential ... of the individual. ref name tapiero cite journal last Tapiero first H. coauthors et al. title L Arginine ... to synthesize or create arginine internally, making the amino acid nutritionally essential for them. ref cite journal last Wu first G. coauthors et al. title Arginine deficiency in preterm infants ... for the synthesis of small L small arginine, including surgical or other trauma, sepsis and burns. Citation needed date June 2011 Arginine was first isolated from a lupin seedling extract in 1886 by the Swiss chemist Ernst Schultze. In general, most people do not need to take arginine supplements because the body usually produces enough. ref http www.mayoclinic.com health l arginine NS patient arginine Mayo Clinic ref Structure The amino acid side chain of arginine consists of a 3 carbon aliphatic ... Betaine Arginine.png thumb left 250px Delocalization of charge in guanidinium group of L Arginine With a Acid ... properties to arginine. Because of the Conjugated system conjugation between the double bond and the nitrogen ... bond H bonds . Sources Dietary sources Arginine is a conditionally nonessential amino acid, meaning ... through the diet. The biosynthetic pathway however does not produce sufficient arginine, and some ... may be advised to increase their intake of foods containing arginine. Arginine is found in a wide variety of foods, including ref cite web url http www.keysupplements.com articles L Arginine Supplements Nitric Oxide Scientific Studies.htm title L Arginine Supplements Nitric Oxide Scientific Studies ... more details
protein Name argininevasopressin receptor 1A caption image width HGNCid 895 Symbol AVPR1A AltSymbols argininevasopressin receptor 1A AVPR1 EntrezGene 552 OMIM 600821 RefSeq NM 000706 UniProt P37288 PDB ECnumber Chromosome 12 Arm q Band 14 LocusSupplementaryData q15 protein Name argininevasopressin receptor 1B caption image width HGNCid 896 Symbol argininevasopressin receptor 1B AVPR1B AltSymbols ... 32 LocusSupplementaryData protein Name argininevasopressin receptor 2 caption image width HGNCid 897 Symbol argininevasopressin receptor 2 AVPR2 AltSymbols DIR3, DIR EntrezGene 897 OMIM 300538 RefSeq NM 000054 UniProt P30518 PDB ECnumber Chromosome X Arm q Band 28 LocusSupplementaryData A vasopressin receptor is a cell surface Receptor biochemistry receptor which binds vasopressin . ref name ... wikitable Receptor Gene G protein Functions Argininevasopressin receptor 1A AVPR1A Gq alpha subunit G sub q sub Vasoconstriction Argininevasopressin receptor 1B br also called Argininevasopressin receptor 3 AVPR1B G sub q sub Neural Argininevasopressin receptor 2 AVPR2 Gs alpha subunit G sub ..., AVPR2 s primary function is to respond to argininevasopressin by stimulating mechanisms ... M, Barberis C title Molecular neurobiology and pharmacology of the vasopressin oxytocin receptor ... title Vasopressin receptors journal Trends Endocrinol. Metab. volume 11 issue 10 pages 406 10 year 2000 month December pmid 11091117 doi 10.1016 S1043 2760 00 00304 0 url issn ref The three types of vasopressin ... adenylate cyclase . ref name pmid11091117 These three receptors for vasopressin have unique tissue ... Treatment Vasopressin receptor antagonist s are drugs that block the action that occurs at the vasopressin ... failure. Vasopressin receptor antagonists include the new class of vaptan drugs , including lixivaptan ... 1326 title Vasopressin and Oxytocin Receptors accessdate author authorlink coauthors date format ... Pharmacology pages language archiveurl archivedate quote MeshName Vasopressin Receptors biochemistry ... more details
Unreferenced stub auto yes date December 2009 Vasopressin analogues are chemicals similar in function but not necessarily similar in structure to vasopressin ADH , such as desmopressin . Desmopressin is administered as an oral spray to treat diseases where ADH is either not being produced in sufficient amounts, or vasopressin s receptor biochemistry receptor s are not being stimulated by the vasopressin. An example of desmopressin s use is for childhood bed wetting, where it is believed that children s circadian rhythms are not synchronized with normal light dark cycles, and consequentially the ADH surge normal children experience at night is not experienced in these children. Taking a desmopressin dose 30 45 minutes before sleeping results in concentrated urine production, and the urination reflex experienced when the bladder fills above a certain level is not triggered. Pituitary and hypothalamic hormones and analogues DEFAULTSORT Vasopressin Analogue Category Pharmacology systemic hormonal drug stub ... more details
enzyme Name arginine racemase EC number 5.1.1.9 CAS number 37290 94 1 IUBMB EC number 5 1 1 9 GO code 0047679 image width caption In enzymology , an arginine racemase EC number 5.1.1.9 is an enzyme that catalysis catalyzes the chemical reaction L arginine math rightleftharpoons math D arginine Hence, this enzyme has one substrate biochemistry substrate , L arginine , and one product chemistry product , D arginine . This enzyme belongs to the family of isomerase s, specifically those racemase s and epimerase s acting on amino acid s and derivatives. The systematic name of this enzyme class is arginine racemase . This enzyme participates in 3 metabolism metabolic pathways lysine degradation , D glutamine and D glutamate metabolism, and D arginine and D ornithine metabolism. It employs one cofactor biochemistry cofactor , pyridoxal phosphate . References reflist 1 cite journal author Yorifuji T, Ogata K, Soda K date 1969 title Crystalline arginine racemase journal Biochem. Biophys. Res. Commun. volume 34 pages 760&ndash 4 pmid 5779761 doi 10.1016 0006 291X 69 90244 7 issue 6 isomerase stub Category EC 5.1.1 Category Pyridoxal phosphate enzymes Category Enzymes of unknown structure ... more details
enzyme Name arginine kinase EC number 2.7.3.3 CAS number 9026 70 4 IUBMB EC number 2 7 3 3 GO code 0004054 image width caption In enzymology , an arginine kinase EC number 2.7.3.3 is an enzyme that catalysis catalyzes the chemical reaction ATP L arginine math rightleftharpoons math ADP Nomega phospho L arginine Thus, the two substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP and L arginine , whereas its two product chemistry products are adenosine diphosphate ADP and Nomega phospho L arginine . This enzyme belongs to the family of transferase s, specifically those transferring phosphorus containing groups phosphotransferase s with a nitrogenous group as acceptor. The systematic name of this enzyme class is ATP L arginine Nomega phosphotransferase . Other names in common use include arginine phosphokinase , adenosine 5 triphosphate L arginine phosphotransferase , adenosine 5 triphosphate arginine phosphotransferase , ATP L arginine N phosphotransferasel ATP L arginine , and omega N phosphotransferase . This enzyme participates in arginine and proline metabolism . Structural studies As of late 2007, 8 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB2 1BG0 , PDB2 1M15 , PDB2 1M80 , PDB2 1P50 , PDB2 1P52 , PDB2 1RL9 , PDB2 1SD0 , and PDB2 2J1Q . References reflist 1 cite journal author ELODI P, SZORENYI E date 1956 title Properties of crystalline arginine phosphoferase isolated from Crustacean muscle journal Acta. Physiol. Hung. volume 9 pages 367&ndash 79 pmid 13339436 issue 4 cite journal author MORRISON JF, GRIFFITHS DE, ENNOR AH date 1957 title The purification and properties of arginine phosphokinase journal Biochem. J. volume 65 pages 143&ndash 53 pmid 13403885 issue 1 pmc 1199841 cite journal author Z date 2006 title In vitro fertilization at our department. A decade ... 5 triphosphate arginine phosphotransferase from lobster muscle purification and properties journal ... more details
enzyme Name arginine deiminase EC number 3.5.3.6 CAS number 9027 98 9 IUBMB EC number 3 5 3 6 GO code 0016990 image width caption In enzymology , an arginine deiminase EC number 3.5.3.6 is an enzyme that catalysis catalyzes the chemical reaction L arginine H sub 2 sub O math rightleftharpoons math L citrulline NH sub 3 sub Thus, the two substrate biochemistry substrates of this enzyme are L arginine and water H sub 2 sub O , whereas its two product chemistry products are Citrulline L citrulline and ammonia NH sub 3 sub . This enzyme belongs to the family of hydrolase s, those acting on carbon nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is L arginine iminohydrolase . Other names in common use include arginine dihydrolase , citrulline iminase , and L arginine deiminase . This enzyme participates in arginine and proline metabolism . Structural studies As of late 2007, 7 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1LXY , PDB link 1RXX , PDB link 1S9R , PDB link 2A9G , PDB link 2AAF , PDB link 2ABR , and PDB link 2ACI . References reflist 1 cite journal author OGINSKY EL, GEHRIG RF date 1952 title The arginine dihydrolase system of Streptococcus faecalis. II Properties of arginine desimidase journal J. Biol. Chem. volume 198 pages 799 805 pmid 12999797 issue 2 cite journal author Petrack B, Sullivan L and Ratner S date 1957 title Behavior of purified arginine desiminase from S. faecalis journal Arch. Biochem. Biophys. volume 69 pages 186 197 doi 10.1016 0003 9861 57 90485 X pmid 13445192 cite journal author RATNER S date 1954 title Urea synthesis and metabolism of arginine and citrulline journal Adv. Enzymol. Relat. Subj. Biochem. volume 15 pages 319 87 pmid 13158183 hydrolase stub Category EC 3.5.3 Category Enzymes of known structure fr Arginine dihydrolase ... more details
enzyme Name arginine 2 monooxygenase EC number 1.13.12.1 CAS number 9027 36 5 IUBMB EC number 1 13 12 1 GO code 0047678 image width caption In enzymology , an arginine 2 monooxygenase EC number 1.13.12.1 is an enzyme that catalysis catalyzes the chemical reaction L arginine O sub 2 sub math rightleftharpoons math 4 guanidinobutanamide CO sub 2 sub H sub 2 sub O Thus, the two substrate biochemistry substrates of this enzyme are L arginine and oxygen O sub 2 sub , whereas its 3 product chemistry products are 4 guanidinobutanamide , carbon dioxide CO sub 2 sub , and water H sub 2 sub O . This enzyme belongs to the family of oxidoreductase s, specifically those acting on single donors with O sub 2 sub as oxidant and incorporation of two atoms of oxygen into the substrate oxygenases . The oxygen incorporated need not be derived from O with incorporation of one atom of oxygen internal monooxygenases o internal mixed function oxidases . The systematic name of this enzyme class is L arginine oxygen 2 oxidoreductase decarboxylating . Other names in common use include arginine monooxygenase , arginine decarboxylase , arginine oxygenase decarboxylating , and arginine decarboxy oxidase . This enzyme participates in urea cycle and metabolism of amino groups . It has one cofactor biochemistry cofactor the flavin FAD . References reflist 1 cite journal author Olomucki A, Pho DB, Lebar R, Delcambe L, Thoai NV date 1968 title Arginine oxygenase decarboxylating . V. Purification and flavin nature journal Biochim. Biophys. Acta. volume 151 pages 353&ndash 66 pmid 4295160 issue 2 cite journal author Thoai NV and Olomucki A date 1962 title Arginine decarboxy oxydase. I. Caracteres et nature de l enzyme journal Biochim. Biophys. Acta volume 59 pages 533&ndash 544 doi 10.1016 0006 3002 62 90631 5 issue 3 cite journal author Thoai NV and Olomucki A date 1962 title Arginine decarboxy oxydase. II. Oxydation de la canavanine et de l homoarginine en beta guanidopropionamide et en delta guanidovaleramide ... more details
Refimprove date July 2009 Arginine alpha ketoglutarate AAKG is a salt chemistry salt of the amino acid arginine and alpha Ketoglutaric acid alpha ketoglutaric acid . It is marketed as a body building supplement. The components are intermediates in the metabolism of Nitric Oxide nitric oxides , but no reputable scientific evidence shows any benefits from taking AAKG as a dietary supplement . At present, there is no research published in Peer review peer reviewed journals to support the assertion that an increase in nitric oxide levels promotes greater muscle protein synthesis or improves muscle strength. There is also no evidence that the arginine alpha ketoglutarate in nitric oxide supplements have any effect on nitric oxide levels in muscles. ref http baye.com no supplements no way 2 High Intensity Training by Drew Baye NO Supplements? No Way Bot generated title ref Verify credibility date July 2009 A recent study examined the effects of AAKG supplementation on heart rate, blood pressure, blood flow, NOx NO2 levels, and l arginine levels. Minimal observed changes were attributed to resistance exercise used in the experimental design, not to AAKG supplementation, although arginine levels were found to have been elevated. ref cite journal last Willoughby first DS coauthors Boucher T, Reid J, Skelton G, Clark M title Effects of 7 days of arginine alpha ketoglutarate supplementation on blood flow, plasma L arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise journal International Journal of Sport Nutrition and Exercise Metabolism year 2011 month Aug volume 21 issue 4 pages 291 9 pmid 21813912 ref Another recent study found acute AAKG ... should be questioned. ref cite journal last Greer first BK coauthors BT Jones title Acute arginine ... 7 pages 1789 94 pmid 21399536 ref References Reflist DEFAULTSORT Arginine Alphaketoglutarate Category ... on exercise performance of l arginine ketoglutarate in trained adult men. Nutrition, 22 9 , 872 ... more details
Drugbox verifiedrevid 428758397 Combo data type combo component1 Arginine class1 amino acid component2 Glutamic acid class2 amino acid Clinical data tradename Drugs.com drugs.com international arginine glutamate pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X pregnancy category legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V legal status routes of administration Identifiers CAS number 4320 30 3 ATC prefix A05 ATC suffix BA01 PubChem 165268 DrugBank Ref drugbankcite correct drugbank DrugBank Chemical data Arginine glutamate is a mixture of two amino acid s, arginine and glutamic acid , used in liver therapy. Bile and liver therapy Category Amino acids Category Combination drugs gastrointestinal drug stub ... more details
Merge to Tidiacic Discuss Talk Tidiacic arginine date February 2010 Drugbox Combo data type combo component1 Tidiacic class1 hepatoprotective component2 Arginine class2 amino acid Clinical data tradename pregnancy AU A B1 B2 B3 C D X pregnancy US A B C D X legal AU S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled legal CA Schedule I, II, III, IV, V, VI, VII, VIII legal UK GSL, P, POM, CD, or Class A, B, C legal US OTC Rx only Schedule I, II, III, IV, V Identifiers CAS number 30986 62 0 ATC prefix A05 ATC suffix BA07 ChemSpiderID 142008 Chemical data Tidiacic arginine trade name Tiadilon is a drug marketed as a hepatoprotection hepatoprotective . It is a 1 1 combination of the amino acid arginine and tidiacic thiazolidine 2,4 dicarboxylic acid , which acts as a sulfur donor. ref Cite web url http www.biam2.org www Sub2147.html title Arginine Tidiacic date February 2, 1999 language French publisher BIAM Retrieved on January 6, 2009. ref In France, its indications and use have been described as identical to those of silibinin silymarin . ref Cite book last Laure first Patrick coauthors Caroline Bislinger title Les m dicaments d tourn s chapter Les produits d tourn s A05. M dicaments h patobiliaires language French page 169 year 2003 publisher Elsevier Masson isbn 978 2 294 00859 7 url http books.google.com ?id tpxDRkxilvAC&pg PA169 Retrieved on January 6, 2009 through Google Book Search . ref References references Further reading Cite journal author Rizzo S title Clinical trial with arginine tidiacicate in symptomatic chronic persistent hepatitis journal Int J Clin Pharmacol Res volume 6 issue 3 pages 225 30 year 1986 pmid 3527997 Bile and liver therapy Gastrointestinal drug stub Category Drugs acting on the gastrointestinal system and metabolism Category Combination drugs ... more details
enzyme Name arginine decarboxylase EC number 4.1.1.19 CAS number 9024 77 5 IUBMB EC number 4 1 1 19 GO code 0008792 image width caption In enzymology , an arginine decarboxylase EC number 4.1.1.19 is an enzyme that catalysis catalyzes the chemical reaction L arginine math rightleftharpoons math agmatine CO sub 2 sub Hence, this enzyme has one substrate biochemistry substrate , L arginine , and two product chemistry products , agmatine and carbon dioxide CO sub 2 sub . This enzyme belongs to the family of lyase s, specifically the carboxy lyases, which cleave carbon carbon bonds. The systematic name of this enzyme class is L arginine carboxy lyase agmatine forming . Other names in common use include SpeA , and L arginine carboxy lyase . This enzyme participates in urea cycle and metabolism of amino groups and glutamate metabolism . It employs one cofactor biochemistry cofactor , pyridoxal phosphate . Structural studies As of late 2007, 5 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1MT1 , PDB link 1N13 , PDB link 1N2M , PDB link 2NV9 , and PDB link 2NVA . References reflist 1 cite journal author Blethen SL, Boeker EA, Snell EE date 1968 title Argenine sic decarboxylase from Escherichia coli. I. Purification and specificity for substrates and coenzyme journal J. Biol. Chem. volume 243 pages 1671&ndash 7 pmid 4870599 issue 8 cite journal author Ramakrishna S, Adiga PR date 1975 title Arginine decarboxylase from Lathyrus sativus seedlings. Purification and properites journal Eur. J. Biochem. volume 59 pages 377&ndash 86 pmid 1252 doi 10.1111 j.1432 1033.1975.tb02465.x issue 2 cite journal author Taylor ES and Gale EF date 1945 title Studies on bacterial amino acid decarboxylases. 6. Codecarboxylase content and action of inhibitors journal Biochem. J. volume 39 issue 1 pages 52&ndash 58 pmid 16747854 pmc 1258148 4.1 enzyme stub Category EC 4.1.1 Category Pyridoxal phosphate enzymes Category Enzymes ... more details
Soupart first2 A last3 Vassart first3 G title Non peptide argininevasopressin antagonists the vaptans ...A vasopressin receptor antagonist is an agent which interferes with action at the vasopressin receptor s. They can be used in the treatment of hyponatremia , especially in patients with congestive heart failure or liver cirrhosis . ref name pmid16843091 Cite journal author Palm C, Pistrosch F, Herbrig K, Gross P title Vasopressin antagonists as aquaretic agents for the treatment of hyponatremia journal Am. J. Med. volume 119 issue 7 Suppl 1 pages S87 92 year 2006 month July pmid 16843091 doi 10.1016 j.amjmed.2006.05.014 url http linkinghub.elsevier.com retrieve pii S0002 9343 06 00549 3 ref Types Tetracyclines Demeclocycline , a tetracycline antibiotic, is sometimes used to block the action of vasopressin in the kidney in hyponatremia due to inappropriately high secretion of vasopressin Syndrome of inappropriate antidiuretic hormone SIADH , when fluid restriction has failed. ref name pmid103083 Cite journal author Padfield PL, Hodsman GP, Morton JJ title Demeclocycline in the treatment of the syndrome of inappropriate antidiuretic hormone release with measurement of plasma ADH journal Postgrad Med J volume 54 issue 635 pages 623 7 year 1978 month September pmid 103083 pmc 2425217 doi 10.1136 pgmj.54.635.623 url ref Vaptans A As of 2004 alt new class of medication, the vaptan drugs, act by inhibiting the action of vasopressin on its receptor biochemistry receptor s Argininevasopressin receptor 1A V sub 1A sub , Argininevasopressin receptor 1B V sub 1B sub and Argininevasopressin receptor 2 V sub 2 sub . These receptors have a variety of functions, with the V sub 1A sub and V ... Fur first7 G title Nonpeptide vasopressin receptor antagonists development of selective and orally ... ref ref cite journal last1 Lemmens Gruber first1 R last2 Kamyar first2 M title Vasopressin ... and antagonists Category Receptor antagonists de Vasopressin Antagonisten pl Antagoni ci receptora ... more details
Orphan date August 2011 Infobox protein family Symbol Arg repressor C Name Arginine repressor, C terminal domain image PDB 1xxa EBI.jpg width caption c terminal domain of escherichia coli arginine repressor l arginine complex pb derivative Pfam PF02863 Pfam clan InterPro IPR020899 SMART PROSITE MEROPS SCOP 1aoy TCDB OPM family OPM protein CAZy CDD Infobox protein family Symbol Arg repressor Name Arginine repressor, DNA binding domain Pfam PF01316 Pfam clan InterPro SMART PROSITE MEROPS SCOP 1aoy TCDB OPM family OPM protein CAZy CDD In molecular biology, the arginine repressor ArgR is a repressor of prokaryotic arginine deiminase pathways. The arginine dihydrolase AD pathway is found in many prokaryotes and some primitive eukaryotes, an example of the latter being Giardia lamblia Giardia intestinalis ... 0 url ref The three enzyme anaerobic pathway breaks down L arginine to form 1 Mole unit mol of ATP, carbon dioxide and ammonia . In simpler bacteria, the first enzyme, arginine deiminase , can account for up to 10 of total cell biology cell protein . ref name pmid9504342 Most prokaryotic arginine ... journal author Lu CD, Houghton JE, Abdelal AT title Characterization of the arginine repressor from ... regulator, and will only release the arginine deiminase operon for gene expression expression in the presence of arginine. ref name pmid9851988 cite journal author Maghnouj A, de Sousa Cabral TF, Stalon V, Vander Wauven C title The arcABDC gene cluster, encoding the arginine deiminase pathway of Bacillus licheniformis, and its activation by the arginine repressor argR journal J. Bacteriol ... D, Glansdorff N, Van Duyne GD title Structure of the arginine repressor from Bacillus stearothermophilus ... six DNA binding domains, clustered around a central oligomeric core when bound to arginine. It predominantly .... This hexameric protein Molecular binding bind s DNA at its N terminus to repress arginine biosyntheis or activate arginine catabolism . Some species have several ArgR Homology biology Homology of sequences ... more details
enzyme Name arginine N succinyltransferase EC number 2.3.1.109 CAS number 99676 48 9 IUBMB EC number 2 3 1 109 GO code 0008791 image width caption In enzymology , an arginine N succinyltransferase EC number 2.3.1.109 is an enzyme that catalysis catalyzes the chemical reaction succinyl CoA L arginine math rightleftharpoons math CoA N sub 2 sub succinyl L arginine Thus, the two substrate biochemistry substrates of this enzyme are succinyl CoA and L arginine , whereas its two product chemistry products are coenzyme A CoA and N2 succinyl L arginine . This enzyme belongs to the family of transferase s, specifically those acyltransferase s transferring groups other than aminoacyl groups. The systematic name of this enzyme class is succinyl CoA L arginine N2 succinyltransferase . Other names in common use include arginine succinyltransferase , AstA , arginine and ornithine N2 succinyltransferase , AOST , AST , and succinyl CoA L arginine 2 N succinyltransferase . This enzyme participates in arginine and proline metabolism . Structural studies As of late 2007, only one tertiary structure structure has been solved for this class of enzymes, with the Protein Data Bank PDB accession code PDB link 1YLE . References reflist 1 cite journal author Vander Wauven C, Jann A, Haas D, Leisinger T, Stalon V date 1988 title N2 succinylornithine in ornithine catabolism of Pseudomonas aeruginosa journal ... of arginine in Pseudomonas cepacia journal J. Bacteriol. volume 164 pages 882&ndash 6 pmid 2865249 ... specific for both arginine and ornithine journal Eur. J. Biochem. volume 224 pages 853&ndash 61 pmid ... and characterization of the aru genes encoding enzymes of the catabolic arginine succinyltransferase ... Arginine catabolism and the arginine succinyltransferase pathway in Escherichia coli journal J. Bacteriol ..., Glansdorff N, Pierard A, Stalon V date 1986 title Biosynthesis and metabolism of arginine in bacteria ... of arginine in bacteria journal Microbiol. Rev. volume 51 pages 178 pmid 16350242 issue ... more details
enzyme Name N2 2 carboxyethyl arginine synthase EC number 2.5.1.66 CAS number IUBMB EC number 2 5 1 66 GO code image width caption In enzymology , a N2 2 carboxyethyl arginine synthase EC number 2.5.1.66 is an enzyme that catalysis catalyzes the chemical reaction D glyceraldehyde 3 phosphate L arginine math rightleftharpoons math N sub 2 sub 2 carboxyethyl L arginine phosphate Thus, the two substrate biochemistry substrates of this enzyme are D glyceraldehyde 3 phosphate and L arginine , whereas its two product chemistry products are N2 2 carboxyethyl L arginine and phosphate . This enzyme belongs to the family of transferase s, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is glyceraldehyde 3 phosphate L arginine N2 2 hydroxy 3 oxopropyl transferase 2 carboxyethyl forming . Other names in common use include CEAS , N2 2 carboxyethyl arginine synthetase , CEA synthetase , glyceraldehyde 3 phosphate L arginine 2 N 2 hydroxy 3 oxopropyl , and transferase 2 carboxyethyl forming . This enzyme participates in clavulanic acid biosynthesis . Structural studies As of late 2007, two tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 2IHT and PDB link 2IHV . References reflist 1 cite journal author Caines ME, Elkins JM, Hewitson KS, Schofield CJ date 2004 title Crystal structure and mechanistic implications of N2 2 carboxyethyl arginine synthase, the first enzyme in the clavulanic acid biosynthesis pathway journal J. Biol. Chem. volume 279 pages 5685&ndash 92 pmid 14623876 doi 10.1074 jbc.M310803200 issue 7 cite journal author Khaleeli N, Li R and Townsend CA date 1999 title Origin of the beta lactam carbons in clavulanic acid from an unusual thiamine pyrophosphate mediated reaction journal J. Am. Chem. Soc. volume 121 issue 39 pages 9223&ndash 9224 doi 10.1021 ja9923134 transferase stub Category EC 2.5.1 Category Enzymes of known ... more details
enzyme Name tyrosine arginine ligase EC number 6.3.2.24 CAS number 116036 78 3 IUBMB EC number 6 3 2 24 GO code 0050367 image width caption In enzymology , a tyrosine arginine ligase EC number 6.3.2.24 is an enzyme that catalysis catalyzes the chemical reaction ATP L tyrosine L arginine math rightleftharpoons math AMP diphosphate L tyrosyl L arginine The 3 substrate biochemistry substrates of this enzyme are adenosine triphosphate ATP , L tyrosine , and L arginine , whereas its 3 product chemistry products are adenosine monophosphate AMP , diphosphate , and L tyrosyl L arginine . This enzyme belongs to the family of ligase s, specifically those forming carbon nitrogen bonds as acid D amino acid ligases peptide synthases . The systematic name of this enzyme class is L tyrosine L arginine ligase AMP forming . Other names in common use include tyrosyl arginine synthase , kyotorphin synthase , kyotorphin synthesizing enzyme , and kyotorphin synthetase . References reflist 1 cite journal author Ueda H, Yoshihara Y, Fukushima N, Shiomi H, Nakamura A, Takagi H date 1987 title Kyotorphin tyrosine arginine synthetase in rat brain synaptosomes journal J. Biol. Chem. volume 262 pages 8165&ndash 73 pmid 3597366 month Jun first1 H first2 Y first3 N first4 H first5 A first6 H issue 17 issn 0021 9258 url http www.jbc.org cgi pmidlookup?view long&pmid 3597366 format Free full text ligase stub Category EC 6.3.2 Category Enzymes of unknown structure ... more details
enzyme Name Arginine pyruvate transaminase EC number 2.6.1.84 CAS number IUBMB EC number 2 6 1 84 GO code image width caption Orphan date February 2009 In enzymology , an arginine pyruvate transaminase EC number 2.6.1.84 is an enzyme that catalysis catalyzes the chemical reaction L arginine pyruvate math rightleftharpoons math 5 guanidino 2 oxopentanoate L alanine Thus, the two substrate biochemistry substrates of this enzyme are L arginine and pyruvate , whereas its two product chemistry products are 5 guanidino 2 oxopentanoate and L alanine . This enzyme belongs to the family of transferase s, specifically the transaminases , which transfer nitrogenous groups. The systematic name of this enzyme class is L arginine pyruvate aminotransferase . Other names in common use include arginine pyruvate transaminase , and AruH . References reflist 1 cite journal author Yang Z, Lu CD date 2007 title Characterization of an arginine pyruvate transaminase in arginine catabolism of Pseudomonas aeruginosa PAO1 journal J. Bacteriol. volume 189 pages 3954&ndash 9 pmid 17416668 doi 10.1128 JB.00262 07 issue 11 pmc 1913410 cite journal author Yang Z, Lu CD date 2007 title Functional genomics enables identification of genes of the arginine transaminase pathway in Pseudomonas aeruginosa journal J. Bacteriol. volume 189 pages 3945&ndash 53 pmid 17416670 doi 10.1128 JB.00261 07 issue 11 pmc 1913404 transferase stub Category EC 2.6.1 Category Enzymes of unknown structure ... more details
unreferenced date January 2011 DISPLAYTITLE small L small Arginine ethyl ester Chembox Name small L small Arginine ethyl ester ImageFile L arginine ethyl ester.png ImageSize 200px IUPACName S Ethyl 2 amino 5 diaminomethylideneamino pentanoate OtherNames Arginine ethyl ester LAE Section1 Chembox Identifiers CASNo 28696 31 3 PubChem ChemSpiderID 3839984 SMILES O C OCC C H N CCCNC N N Section2 Chembox Properties C 8 H 18 N 4 O 2 Appearance Density MeltingPt BoilingPt Solubility soluble Section3 Chembox Hazards MainHazards FlashPt Autoignition small L small Arginine ethyl ester or LAE is an alternative supplement form of the conditionally essential amino acid arginine bound to an ethyl ester . Ester s are organic compounds formed by esterification the reaction of carboxylic acid and alcohol s. Physical and chemical properties small L small Arginine ethyl ester is a white powder quickly soluble in hot water. It has a characteristically bad and bitter taste, thus before drinking it is recommended to mix the powder with a stronly flavored beverage or citrus juice. Dubious Dihydrochloride or not date April 2010 Uses small L small Arginine ethyl ester is biochemical reagent which can be used as a pharmaceutical intermediate. References Reflist Dietary supplements DEFAULTSORT Arginine ethyl ester, L Category Dietary supplements Category Amino acid derivatives Category Ethyl esters ... more details
DISPLAYTITLE N Propyl small L small arginine chembox verifiedrevid 335844932 Name N Propyl small L small arginine ImageFile N Propyl L arginine.png ImageSize 200px IUPACName 2 S 2 Amino 5 N propylcarbamimidoyl amino pentanoic acid OtherNames NPLA Section1 Chembox Identifiers CASNo 137361 05 8 PubChem 447180 SMILES CCCN C N NCCC C H C O O N Section2 Chembox Properties Formula C sub 9 sub H sub 20 sub N sub 4 sub O sub 2 sub MolarMass 216.28 g mol Appearance Density MeltingPt BoilingPt Solubility Section3 Chembox Hazards MainHazards FlashPt Autoignition N Propyl small L small arginine , or more properly N sup G sup propyl small L small arginine NPA , is a selective inhibitor of neuronal nitric oxide synthase nNOS . DEFAULTSORT Propyl L arginine, N Category Amino acids Category Guanidines organic compound stub ... more details
enzyme Name protein arginine deiminase EC number 3.5.3.15 CAS number 75536 80 0 IUBMB EC number 3 5 3 15 GO code 0004668 image width caption In enzymology , a protein arginine deiminase EC number 3.5.3.15 is an enzyme that catalysis catalyzes a form of post translational modification called arginine de imination or citrullination protein L arginine H sub 2 sub O math rightleftharpoons math protein L citrulline NH sub 3 sub Thus, the two substrate biochemistry substrates of this enzyme are protein L arginine and water H sub 2 sub O , whereas its two product chemistry products are protein L citrulline and ammonia NH sub 3 sub . This enzyme belongs to the family of hydrolase s, those acting on carbon nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is protein L arginine iminohydrolase . This enzyme is also called peptidylarginine deiminase . Structural studies As of late 2007, 7 tertiary structure structures have been solved for this class of enzymes, with Protein Data Bank PDB accession codes PDB link 1WD8 , PDB link 1WD9 , PDB link 1WDA , PDB link 2DEW , PDB link 2DEX , PDB link 2DEY , and PDB link 2DW5 . See also PADI1 PADI2 PADI3 PADI4 References reflist 1 cite journal author Fujisaki M, Sugawara K date Tokyo title Properties of peptidylarginine deiminase from the epidermis of newborn rats journal J. volume Biochem. pages 257&ndash 63 pmid 7217033 issue 1 MeshName protein arginine deiminase hydrolase stub Carbon nitrogen non peptide hydrolases Category EC 3.5.3 Category Enzymes of known structure ... more details
DISPLAYTITLE small L small Arginine small L small pyroglutamate Mergeto arginine date April 2010 Chembox Name small L small Arginine small L small pyroglutamate ImageFileL1 L Arginine L pyroglutamate.png ImageSizeL1 120px ImageNameL1 Arginine Pyroglutamate ImageFileR1 L Arginine L pyroglutamate 3D.png ImageSizeR1 120px ImageNameR1 Arginine Pyroglutamate IUPACName 2 S 2 amino 5 diaminomethylideneamino pentanoic acid 2 S 5 oxopyrrolidine 2 carboxylic acid 1 1 OtherNames Section1 Chembox Identifiers InChI 1 C6H14N4O2.C5H7NO3 c7 4 5 11 12 2 1 3 10 6 8 9 7 4 2 1 3 6 4 5 8 9 h4H,1 3,7H2, H,11,12 H4,8,9,10 3H,1 2H2, H,6,7 H,8,9 t4 m0. s1 InChIKey UYCAGRPOUWSBIQ WCCKRBBIBE CASNo 56265 06 6 PubChem 198346 ... small L small Arginine small L small pyroglutamate , also known as pirglutargine and arginine pidolate , is the L arginine small L small arginine salt of pyroglutamic acid . Arginine pyroglutamate is a delivery ..., fruit, dairy products and meat. Arginine has been widely used because of its role in synthesis ... February title Supplement Looking Ahead in Honoring the Past. Arginine beyond protein journal American ... arginine and related amino acids useful in treating insufficiencies of the urea cycle e.g. ... author Gautam Cherla, and Edgar A. Jaimes year 2004 month October title Role of L Arginine in the Pathogenesis ..., PhD, Linda Cowan, RN, CWS year 2005 month title Arginine Supplementation and Wound Healing journal ... url quote ref ref cite journal author Sidney M Morris, Jr year 2005 month title Arginine metabolism ... in arginine glycine amidinotransference and guanidinoacetate methyltransferase. ref cite journal ... quote ref The ability of arginine to stimulate the pancreatic and pituitary axis has been used to alleviate ... 1987 month title Effects of arginine pyroglutamate Adiuvant on growth hormone in children journal Clin ... C. year 1999 month December title Chronic arginine aspartate supplementation in runners reduces total ... L small Arginine small L small pyroglutamate is a crystalline solid powder with a sour taste. It is easily ... more details
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